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Ivtrim Inj 5Ml is a combination medicine used in the treatment of bacterial infections of the urinary tract, respiratory tract, ear, lungs, skin, brain and toxoplasmosis. It contains trimethoprim and sulfamethoxazole which stops the production of tetrahydrofolic acid and dihydrofolic acid and thereby stops the growth of the infection-causing bacteria. Sometimes, your may experience common side effects like headache, nausea, diarrhoea, and skin rashes.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Converge Biotech Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Ivtrim Inj 5Ml

Ivtrim Inj 5Ml belongs to the group of medicines called ‘antibiotics’ used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Ivtrim Inj 5Ml does not work against infections caused by the virus, including cold and flu. 

Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim and Sulfamethoxazole. Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Ivtrim Inj 5Ml stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Ivtrim Inj 5Ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Ivtrim Inj 5Ml, please inform your doctor if you have any allergy (against any antibiotic), severe kidney or liver problems, porphyria (blood disorder), or blood problems which may cause bleeding or bruising. Inform your doctor if you are pregnant or breastfeeding before receiving this injection. Ivtrim Inj 5Ml is not recommended for infants below 6 weeks. Keep your doctor informed about your medical history and your ongoing medications to rule out any side effects/interactions.

Uses of Ivtrim Inj 5Ml

Ivtrim Inj 5Ml is used to treat a variety of bacterial infections. The detailed uses of Ivtrim Inj 5Ml are as follows:

  • Urinary tract infections (UTIs): Ivtrim Inj 5Ml effectively treats UTIs by targeting and killing bacteria in the urinary tract.
  • Respiratory tract infections: It is used to manage conditions like bronchitis and pneumonia by eliminating the responsible bacterial pathogens.
  • Ear infections (Otitis media): Ivtrim Inj 5Ml helps relieve bacterial ear infections, especially in children.
  • Skin and soft tissue infections: It is effective in treating bacterial infections of the skin caused by susceptible organisms.
  • Toxoplasmosis: Ivtrim Inj 5Ml is also prescribed in the treatment and prevention of toxoplasmosis, a parasitic infection caused by Toxoplasma gondii:Broad-spectrum antibacterial action: As a combination of Trimethoprim and Sulfamethoxazole, Ivtrim Inj 5Ml works synergistically to inhibit the bacterial synthesis of folic acid, which is essential for their growth and survival.

Key Benefits

Ivtrim Inj 5Ml belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Ivtrim Inj 5Ml kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. Ivtrim Inj 5Ml is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Ivtrim Inj 5Ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Ivtrim Inj 5Ml Works

Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim and Sulfamethoxazole. Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Ivtrim Inj 5Ml stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.
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Alcohol

Caution

Avoid alcohol consumption while taking Ivtrim Inj 5Ml to prevent unpleasant side effects.

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Pregnancy

Caution

Please inform your doctor before taking Ivtrim Inj 5Ml if you are pregnant. Ivtrim Inj 5Ml may cause fetal harm. Your doctor will prescribe Ivtrim Inj 5Ml only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Ivtrim Inj 5Ml as it may cause bilirubin displacement and kernicterus (brain damage resulting from high levels of bilirubin in the blood). Please consult your doctor if you have any concerns.

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Driving

Caution

It is unknown whether Ivtrim Inj 5Ml affects your ability to drive and operate machinery. Drive only if you are physically stable and mentally focused.

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Liver

Caution

Please inform your doctor before taking Ivtrim Inj 5Ml if you have liver impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative if necessary based on your condition.

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Kidney

Caution

Please inform your doctor before taking Ivtrim Inj 5Ml if you have kidney impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative if necessary based on your condition.

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Children

Caution

Ivtrim Inj 5Ml is not recommended for infants below 6 weeks.

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Heart

Caution

Ivtrim Inj 5Ml can be used in heart patients, but with caution due to potential drug interactions. It may increase levels of medications like digoxin or procainamide, so close monitoring is essential.

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Geriatrics

Caution

Geriatric patients can receive Ivtrim Inj 5Ml, but it may be more prone to side effects like kidney impairment or electrolyte imbalances. Dose adjustments and regular monitoring help ensure safe use.

What if I have taken an overdose of Ivtrim Inj 5Ml

Ivtrim Inj 5Ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Overdose of Ivtrim Inj 5Ml may cause nausea/vomiting, headache, mental depression, confusion, thrombocytopenia, uremia, and loss of appetite. Your doctor will initiate necessary measures when an overdose is suspected.

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

 

Have a query?

How Soon It Starts Working

The time required for Ivtrim Inj 5Ml to start to work: The onset time of Ivtrim Inj 5Ml has not been clinically established. The time for which the effects of Ivtrim Inj 5Ml last: The duration of Ivtrim Inj 5Ml’s effect is clinically not established.

What if you forget to take Ivtrim Inj 5Ml

As this medicine is administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight. • Keep Ivtrim Inj 5Ml out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Do not take Ivtrim Inj 5Ml if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (a rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Ivtrim Inj 5Ml if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. 

Drug-Drug Interactions

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Drug-Drug Interactions: Ivtrim Inj 5Ml may have interaction with a blood thinner (warfarin), anticonvulsants (phenytoin), digitalis glycoside (digoxin), oral hypoglycemic agents, anti-HIV (zidovudine), anti-arrhythmic (procainamide).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), hematologic (blood) toxicity, hypersensitivity reactions, porphyria (rare blood problem that affects the skin or nervous system), folate deficiency, crystalluria (cloudy urine), dialysis, urinary obstruction, kidney and liver dysfunction.

Severe

Drug-Drug Interactions

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How does the drug interact with Ivtrim Inj 5Ml:
Using trimethoprim and sulfamethoxazole with BCG vaccine can reduce the effect of BCG vaccine

How to manage the interaction:
Taking Trimethoprim and sulfamethoxazole with BCG vaccine may lead to an interaction, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Ivtrim Inj 5Ml:
Taking Potassium iodide with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Potassium iodide with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Taking Ramipril with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Ramipril with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Taking Ropivacaine with Trimethoprim and sulfamethoxazole can lead to increased risk of side effects.

How to manage the interaction:
Although taking Ropivacaine with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience gray coloured skin, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, difficulty in breathing, increased heartrate, anxiety or confusion . Do not stop using any medications without talking to a doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Taking Azilsartan medoxomil with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Azilsartan medoxomil with sulfamethoxazole and trimethoprim may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Taking Potassium chloride with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Potassium chloride with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Ivtrim Inj 5Ml:
Taking Potassium gluconate with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Potassium gluconate with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Taking Quinapril with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Quinapril with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Taking Benazepril with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Benazepril with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Taking Losartan with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Losartan with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTIC COMBINATION]

FAQs

Ivtrim Inj 5Ml belongs to the group of medicines called antibiotics used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma).

Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Ivtrim Inj 5Ml kills the bacteria and stops their growth. Thus, it helps to treat bacterial infections.

Ivtrim Inj 5Ml causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Diarrhoea might be a side-effect of Ivtrim Inj 5Ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, inform your doctor. Do not take anti-diarrheal medicine on your own.

Ivtrim Inj 5Ml may affect certain laboratory test results. Inform the lab technician that you are taking Ivtrim Inj 5Ml.

Ivtrim Inj 5Ml may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Ivtrim Inj 5Ml.

Disclaimer

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Author Details

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Country of origin

INDIA

Manufacturer/Marketer address

7-2-1813,/5/A/1, Vasavi'S Central Court, Unit-Ii , 3Rd Floor, Czech Colony, Sanath Nagar, Hyderabad - 500018., Telangana State, India.
Other Info - IVT0001
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