Apollo
logo

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Not for online sale
Product icon
Check at a nearby store
Trailing icon
compositionComposition:ETHAMBUTOL-800MG+ISONIAZID-300MG
prescription
Prescription Medicine
info
image icons

ISOKOXI 800MG is used to treat tuberculosis (TB). It contains Isoniazid and Ethambutol which work by inhibiting the growth of tuberculosis-causing bacteria. In some cases, this medicine may cause side effects such as weakness, general discomfort, fatigue, loss of appetite, nausea or vomiting, dark urine, and vision problems. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

Read more
Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

ETHAMBUTOL-800MG+ISONIAZID-300MG

Manufacturer/Marketer :

Shreya Life Sciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About ISOKOXI 800MG

ISOKOXI 800MG is a prescription medication used to treat tuberculosis, a serious bacterial infection that mainly affects the lungs. This medicine works by targeting and stopping the growth of the bacteria responsible for the infection. It is prescribed as part of a multi-drug regimen to completely clear the infection from your body.

This medication is taken daily, and it is crucial to take it consistently at the same time every day to prevent the bacteria from becoming resistant. You should ideally take it on an empty stomach, either 1 hour before or 2 hours after a meal, for the best absorption. Making healthy lifestyle choices, such as eating a nutrient-rich diet and avoiding tobacco use, can support your body's immune system during recovery.

While taking ISOKOXI 800MG, you may experience mild side effects like a temporary upset stomach or mild joint pain. However, you must contact your doctor immediately if you experience serious symptoms such as vision changes, severe abdominal pain, or yellowing of your eyes and skin. Your healthcare provider will monitor you closely throughout your treatment.

Do not take this if you have severe liver damage, a history of nerve damage in your eyes, or if you have had an allergic reaction to this medication in the past. Talk to your doctor before starting this medicine if you have kidney disease, gout, or diabetes, as these conditions may require special care.

This medicine can interact with alcohol, which greatly increases your risk of severe liver damage, so it is important to avoid drinking alcohol during treatment. You should also consult your doctor before using this medicine if you are pregnant, breastfeeding, or are an elderly individual, as your treatment plan may need special monitoring.

Uses of ISOKOXI 800MG

ISOKOXI 800MG is used to treat tuberculosis. The detailed uses of ISOKOXI 800MG are as follows:

  • Tuberculosis (TB) treatment: ISOKOXI 800MG is used to treat active tuberculosis infections. It works in combination with other medicines to eliminate the bacteria from your organs and prevent the disease from spreading to other people.

Key Benefits

ISOKOXI 800MG provides effective, combination therapy to help treat tuberculosis (TB) by eliminating the bacteria responsible for the infection and reducing the risk of disease progression. When used as prescribed alongside other anti-tuberculosis medicines, it offers several important health benefits:

  • Effective Clearance of Tuberculosis Infection: ISOKOXI 800MG provides a highly effective way to eliminate tuberculosis bacteria from your body, allowing your lungs and other affected tissues to heal. By clearing the infection, it helps relieve symptoms such as persistent cough, night sweats, unexplained weight loss, and severe fatigue.
  • Simplified Treatment Regimen: Because it combines two critical anti-tuberculosis medicines into a single tablet, ISOKOXI 800MG simplifies your daily treatment plan. This makes it easier to keep track of your doses, improves treatment adherence, and supports completion of the full course of therapy.
  • Helps Prevent Drug Resistance and Recurrence: When taken as prescribed as part of combination anti-tuberculosis therapy, ISOKOXI 800MG helps prevent tuberculosis bacteria from developing resistance to treatment. This improves the likelihood of complete cure and significantly reduces the risk of the infection returning in the future.

Directions for Use

  • Take ISOKOXI 800MG on an empty stomach, preferably at least one hour before breakfast or a snack, or two hours after a meal, or as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow ISOKOXI 800MG as a whole with a glass of water.
  • Do not crush, break, or chew it.

How ISOKOXI 800MG Works

ISOKOXI 800MG combines two distinct active ingredients that work together in different ways to destroy tuberculosis bacteria. The first active component, isoniazid, stops the bacteria from building their outer protective walls. It does this by blocking the production of mycolic acids, which are essential building blocks for the bacterial cell wall. Without a strong wall, the bacteria cannot survive and eventually die. The second active component, ethambutol, inhibits arabinosyl transferase, an enzyme needed to produce arabinogalactan, an essential component of the mycobacterial cell wall. Without this structural component, the bacterial cell wall becomes weakened, making it difficult for the bacteria to grow and survive.
bannner image

Alcohol

Caution

Consumption of alcohol may increase the risk of side-effects and worsen the condition.

bannner image

Pregnancy

Caution

ISOKOXI 800MG should be used with caution in pregnant women. It is given to pregnant women only if clinically needed when the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

ISOKOXI 800MG should be used with caution in breastfeeding mothers. It is given to breastfeeding mothers only when the benefits outweigh the risks.

bannner image

Driving

Caution

ISOKOXI 800MG may cause dizziness in some people. So, do not drive or operate heavy machinery if you are not fully alert.

bannner image

Liver

Caution

ISOKOXI 800MG is not recommended for patients with severe liver problems. In mild to moderate liver diseases, the dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

ISOKOXI 800MG should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

bannner image

Children

Caution

ISOKOXI 800MG should be used with caution in children. The dose may have to be adjusted based on age, body weight and healthy history of the child.

bannner image

Heart

Caution

ISOKOXI 800MG can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

bannner image

Geriatrics

Consult your doctor

ISOKOXI 800MG should be given to elderly patients only if recommended by a doctor. Please consult your doctor before using ISOKOXI 800MG.

What if I have taken an overdose of ISOKOXI 800MG

If you take too much of this medication, seek immediate emergency medical care or contact a poison control centre right away. Symptoms of an overdose may include severe dizziness, slurred speech, blurred vision, seizures, loss of consciousness, and severe metabolic acidosis. An overdose of isoniazid is a medical emergency and requires immediate hospital treatment.

Diet & Lifestyle Advise

  • Avoid alcohol completely: Alcohol significantly increases the risk of severe liver damage when combined with this medication.
  • Incorporate Vitamin B6 (pyridoxine): Ask your doctor about taking a Vitamin B6 supplement, which is frequently recommended to help prevent nerve pain and tingling in your hands and feet during treatment.
  • Avoid certain foods: Limit foods high in tyramine and histamine, such as aged cheeses, red wine, soy sauce, yeast extracts, and certain fish like tuna. Combining these foods with this medicine can cause a rapid heartbeat, skin flushing, and a sudden rise in blood pressure.
  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys filter and clear the medication safely from your system.
health query

Have a query?

How Soon It Starts Working

The time required for ISOKOXI 800MG to start to work: ISOKOXI 800MG starts to show its action within 1 to 2 hour of administration. The time for which the effects of ISOKOXI 800MG last: ISOKOXI 800MG effect lasts for 24 hours.

What if you forget to take ISOKOXI 800MG

Take the missed dose as soon as you remember. If you miss a dose of ISOKOXI 800MG, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss doses frequently, inform your doctor, as poor adherence may reduce treatment effectiveness and increase the risk of treatment failure or the development of drug-resistant tuberculosis.

Storage

• Store ISOKOXI 800MG at room temperature, strictly between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Get Regular Eye Examinations: Get your vision tested before starting this medicine and have regular eye exams during your treatment, as one of the active ingredients can cause optic nerve irritation.
  • Monitor Your Liver Health: Keep all appointments for regular blood tests, especially liver function tests, so your doctor can monitor your liver health.
  • Avoid Certain Antacids: Do not take antacids containing aluminium within 2 hours of taking your dose, as they can prevent your body from absorbing this medicine properly.
  • Complete the Full Treatment Course: Finish the entire course prescribed to you, even if your symptoms disappear. Stopping early can make the tuberculosis bacteria resistant to antibiotics, making future infections much harder to treat.

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with ISOKOXI 800MG and affect its safety or effectiveness.

  • Antacids: Medications containing aluminium hydroxide can decrease the absorption of ISOKOXI 800MG. Take these medicines at least 2 hours apart.
  • Anticonvulsants: This medicine can increase blood levels of seizure medications like phenytoin or carbamazepine, which may raise the risk of side effects.
  • Hepatotoxic medicines: Taking other medications that can strain the liver (such as high doses of acetaminophen) increases the risk of serious liver damage.

Login/Sign Up

verifiedApollotooltip
  • Tyramine and Histamine-rich foods: Consuming aged cheeses, cured meats, red wine, or skipjack tuna while taking this medicine can lead to flushing, sweating, headaches, or high blood pressure.

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

FAQs

ISOKOXI 800MG is used in the treatment of tuberculosis (TB).
ISOKOXI 800MG contains Isoniazid and Ethambutol. They are bacteriostatic agents (stop the growth of bacteria) and have a similar mode of action. They work by preventing mycolic acid production (an enzyme produced by bacteria) essential for cell wall formation (protective coating, which is necessary for bacteria's survival).
You are recommended to avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, fish such as tuna, salmon and mackerel, wine and beer as they may interact with ISOKOXI 800MG and cause adverse effects such as sweating, headache, dizziness, flushing (reddening of the skin) and uneven heartbeat.
ISOKOXI 800MG may cause side-effects such as weakness, malaise (general discomfort), fatigue (feeling tired), loss of appetite, nausea or vomiting, dark urine, pale stools, jaundice (yellowing of the skin or whites of the eyes) and vision problems. Inform your doctor immediately if any of these side-effects persist or get worse.
ISOKOXI 800MG may affect liver function, so it is not prescribed in patients with severe liver problems and alcohol abuse unless clinically needed. Also, do not consume excessive amounts of alcohol while using ISOKOXI 800MG as it may increase the risk of liver damage.
Yes, ISOKOXI 800MG can affect the action of birth control pills. ISOKOXI 800MG contains isoniazid and ethambutol, which can increase the breakdown of hormones in birth control pills, making them less effective. This could potentially result in an unwanted pregnancy. Please discuss with your doctor if you have any concerns.
Yes, ISOKOXI 800MG can cause urine discolouration. As ISOKOXI 800MG contains isoniazid and ethambutol, which can lead to dark-coloured urine as a common but non-harmful side effect. If the discolouration persists, please consult your doctor.
No, you must completely avoid alcohol while taking ISOKOXI 800MG. Both alcohol and this medication place stress on your liver, and combining them significantly increases your risk of severe, life-threatening liver damage. Talk to your doctor if you have concerns about avoiding alcohol.
One of the components in ISOKOXI 800MG can lower the level of active Vitamin B6 in your body, which can lead to nerve damage causing numbness or tingling in your extremities. Taking a daily Vitamin B6 (pyridoxine) supplement prevents this issue. Talk to your doctor to find out the correct supplement dose for you.
Contact your doctor immediately. Do not stop taking the medicine without medical advice, as unplanned interruptions can contribute to drug resistance.
It is best to take ISOKOXI 800MG on an empty stomach (1 hour before or 2 hours after a meal) for the best absorption. However, if you experience significant stomach discomfort, talk to your doctor, who may suggest taking it with a small, light, non-fatty meal.
Tuberculosis treatment is a long-term process that typically lasts several months. You must take ISOKOXI 800MG for the exact duration prescribed by your doctor, even if you feel completely cured after a few weeks. Talk to your doctor before making any changes to your therapy.
Avoid taking antacids that contain aluminum within 2 hours of taking ISOKOXI 800MG, as aluminum binds to the medication and prevents your body from absorbing it. Talk to your doctor or pharmacist to find safe ways to manage indigestion during your treatment.
If you are pregnant, planning to become pregnant, or breastfeeding, you must consult your doctor before starting ISOKOXI 800MG. Your doctor will carefully weigh the critical benefits of treating tuberculosis against any potential risks to your baby to determine the safest treatment plan.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.9139 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.5310 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Ethambutol Ethambutol. 2007. [Accessed on 09 Apr. 2019]Check here
  4. Isoniazid Isoniazid. 2015. [Accessed on 09 Apr. 2019]Check here
  5. Lee N, Nguyen H. Ethambutol. StatPearls [Internet]. NIH National Library of Medicine. National Center for Biotechnology Information. [Revised in October 2022] [Accessed on 04th March 2023]Check here
  6. Tuberculosis. National Health Service. [Accessed on 04th March 2023]Check here
  7. Chaves RG, Lamounier JA Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98Check here

Country of origin

India

Manufacturer/Marketer address

SHREYA HOUSE, 301/A, Pereira Hill Road, Andheri East, Mumbai - 400 099, India
Other Info - ISO0002
whatsapp Floating Button