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compositionComposition:INDINAVIR-400MG
prescription
Prescription Medicine
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Inbec 400 Capsule is used for the treatment of HIV infection. It contains Indinavir, which works by decreasing the amount of HIV in the blood. It also increases the count of CD4 (T) cells, a type of white blood cell that helps the body fight infection. Common side effects of this medication may include nausea, headache, loss of appetite, and weakness. Inform the doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding whilst on treatment with this medication.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

INDINAVIR-400MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Inbec 400 Capsule

Inbec 400 Capsule is a prescription medicine used to treat human immunodeficiency virus (HIV) infection. It belongs to a class of medicines known as protease inhibitors, which work by managing the amount of virus in the body. When taken alongside other antiretroviral medications, it helps keep the infection under control and protects your immune system from further damage.

To get the best results, you must take Inbec 400 Capsule consistently and at the exact times prescribed by your doctor. It is typically taken on an empty stomach with a full glass of water, although your doctor may adjust these instructions if you take it with other boosting medicines. Maintaining a balanced diet, staying physically active, and avoiding smoking are key lifestyle habits that support your overall immune health while on this treatment.

Some people taking this medicine may experience mild side effects, such as an upset stomach, changes in taste, or dry skin. However, you must contact your doctor immediately if you face serious side effects, such as sharp pain in your back or side, blood in your urine, or yellowing of your skin and eyes.

Before starting this medicine, talk to your doctor if you have a history of liver damage, kidney disease, high blood sugar, or bleeding disorders. Do not take this if you are allergic to any of its ingredients or if you are currently taking certain medicines that interact poorly with it.

This medicine can interact strongly with several other prescription drugs, herbal remedies, and alcohol, which can increase your risk of liver damage or make your treatment less effective. If you are pregnant, breastfeeding, or planning a family, talk to your doctor to understand the risks and benefits of using this medicine.

Uses of Inbec 400 Capsule

Your doctor may prescribe it for the following condition:

  • HIV-1 Infection: Inbec 400 Capsule helps control the virus by preventing it from multiplying in your body, which helps keep your immune system strong and reduces the risk of developing advanced stages of the infection.

Key Benefits

Using Inbec 400 Capsule as prescribed helps control HIV-1 infection and supports long-term immune health. Here are the key benefits you can expect:

  • Supports immune system health: By keeping the virus from multiplying, this medicine helps maintain your body's natural defense cells. This makes you less likely to get sick from other infections.
  • Reduces viral load: It helps lower the amount of the virus in your blood to very low levels, which is a key goal of managing your health over the long term.
  • Promotes daily wellness: When taken consistently as part of a combination plan, it helps you maintain your daily routine, energy levels, and overall physical well-being.
Side effects of Inbec 400 Capsule
  • Stay hydrated by drinking at least 8 glasses of water daily.
  • Limit sodium intake by reducing salty foods.
  • Moderate animal protein by limiting red meat, poultry, and fish.
  • Incorporate calcium-rich plant-based foods like leafy greens and fortified foods.
  • Limit oxalate-rich foods like spinach, rhubarb, beets, chocolate, nuts, and certain berries.
  • Eat citrus fruits like lemons and oranges for citric acid benefits.
  • Exercise regularly with moderate physical activity.
  • Maintain a healthy weight to reduce stone risk.
  • Monitor urine output by tracking volume and color.
  • Keep a food diary to track kidney stone-friendly diet.
  • Consult a healthcare professional to discuss kidney stone type and management plan.
  • High levels of bilirubin in blood leads to yellow discolouration of skin and eyes which is a significant liver issue that needs immediate medical attention.
  • Eating a balanced diet can help manage such side effects and must be taken as a dietician suggests.
  • Exercise regularly to maintain a good metabolism in your body.
  • Avoid alcohol consumption as it can affect liver functioning and worsen if there is a yellow discolouration of the skin and eyes.
  • Prevent toxins from chemicals that can be touched and inhaled. Ensure to manage your medications carefully.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

Directions for Use

  • Inbec 400 Capsule can be taken 1 hour before or 2 hours after a meal, with water, juice, milk, coffee, or tea.
  • It is usually taken every 8 hours; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow the capsule as a whole with a glass of water.
  • Do not crush, open or break Inbec 400 Capsule.

How Inbec 400 Capsule Works

Inbec 400 Capsule contains indinavir, a protease inhibitor that helps treat HIV-1 infection. It works by blocking the HIV protease enzyme, which the virus needs to produce mature, infectious virus particles. As a result, the virus produces defective particles that cannot infect healthy cells. This reduces the amount of HIV in the body, helps protect the immune system, and slows the progression of HIV infection when used as part of combination antiretroviral therapy.
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Alcohol

Consult your doctor

It is not known whether Inbec 400 Capsule interacts with alcohol. Please consult your doctor for more information.

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Pregnancy

Caution

Inbec 400 Capsule belongs to pregnancy category C. It should be used during pregnancy only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Inbec 400 Capsule. HIV-positive women must not breastfeed as HIV infection can be passed to the baby in breast milk.

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Driving

Consult your doctor

It is not known if Inbec 400 Capsule affects your ability to drive. Drive or operate machinery only if you are feeling well.

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Liver

Caution

Please consult your doctor if you have liver problems, particularly if you have mild or moderate liver disease caused by cirrhosis.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Please consult the doctor. Your doctor may prescribe a suitable dose based on your child's age and condition.

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Heart

Caution

Inbec 400 Capsule should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Inbec 400 Capsule.

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Geriatrics

Consult your doctor

Limited information available about the use of Inbec 400 Capsule in geriatric patients. Please consult your physician.

What if I have taken an overdose of Inbec 400 Capsule

If you think you have taken more than the prescribed dose of Inbec 400 Capsule, seek immediate medical attention straight away, even if you do not have any symptoms. Take the medicine pack with you so healthcare professionals know exactly what was taken.

Diet & Lifestyle Advise

  • Drink abundant water: Aim to drink at least 1.5 to 2 liters of water throughout the day to lower your risk of developing painful kidney stones.
  • Watch your fat intake: If your doctor advises taking this medicine with a light meal, ensure it is low in fat, as high-fat meals can make it harder for your body to absorb the medicine properly.
  • Maintain physical activity: Regular exercise can help manage changes in body fat and blood sugar levels, which are sometimes associated with long-term antiviral use.
  • Eat regular, balanced meals: Keep a food diary to track how your stomach reacts to the medicine and to ensure you are getting enough nutrients to support your immune system.
health query

Have a query?

How Soon It Starts Working

The time required for Inbec 400 Capsule to start to work: Inbec 400 Capsule starts to show its action in 2 hours of administration. The time for which the effects of Inbec 400 Capsule last: The effect of Inbec 400 Capsule lasts for 8 hours.

What if you forget to take Inbec 400 Capsule

If you miss a dose, take it as soon as you remember. However, if your next dose is due within a few hours, skip the missed dose and return to your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Inbec 400 Capsule at room temperature, ideally between 68°F and 77°F (20°C and 25°C).

Drug Warnings

  • Check before use: Ensure the capsules are not damp or sticking together before taking them.
  • Keep the drying agent in the bottle: Do not remove the drying agent, as it helps protect the capsules from moisture.
  • Do not stop treatment suddenly: Continue taking Inbec 400 Capsule as prescribed, even if you feel well, unless your doctor tells you to stop.
  • Inform your healthcare provider: Tell your doctor, dentist, or surgeon that you are taking Inbec 400 Capsule before any medical or dental procedure.
  • Separate from antacids: If you take antacids, take them at least 1 hour apart from Inbec 400 Capsule to ensure proper absorption.
  • Maintain physical activity and follow a heart-healthy diet: Regular exercise and a balanced diet may help reduce the risk of body fat redistribution (lipodystrophy), elevated cholesterol, triglycerides, and high blood sugar associated with long-term treatment. Your doctor may monitor these changes with periodic blood tests.

Drug-Drug Interactions

verifiedApollotooltip

  • Cholesterol-lowering medicines: Medicines such as simvastatin and lovastatin may increase the risk of serious muscle damage.
  • Rifampicin: May reduce the effectiveness of Inbec 400 Capsule, making it less effective at controlling HIV.
  • Sedatives: Medicines such as midazolam and triazolam may increase the risk of excessive drowsiness or breathing problems.
  • St John's wort: May lower the levels of Inbec 400 Capsule in the body, reducing its effectiveness.
IndinavirSildenafil
Critical
IndinavirTicagrelor
Critical

Drug-Drug Interactions

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IndinavirSildenafil
Critical
How does the drug interact with Inbec 400 Capsule:
Coadministration of Inbec 400 Capsule and Sildenafil can increase the blood levels and side effects of sildenafil.

How to manage the interaction:
Taking Inbec 400 Capsule and Sildenafil together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
IndinavirTicagrelor
Critical
How does the drug interact with Inbec 400 Capsule:
Using ticagrelor together with Inbec 400 Capsule can cause risk of bleeding.

How to manage the interaction:
Taking Ticagrelor with Inbec 400 Capsule is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
IndinavirAlprazolam
Critical
How does the drug interact with Inbec 400 Capsule:
The combination of Alprazolam and Inbec 400 Capsule may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Alprazolam and Inbec 400 Capsule, it can be used if prescribed by a doctor. Consult a doctor if you have drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
IndinavirSimvastatin
Critical
How does the drug interact with Inbec 400 Capsule:
Combining Inbec 400 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Inbec 400 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
IndinavirAmiodarone
Critical
How does the drug interact with Inbec 400 Capsule:
The combination of Amiodarone and Inbec 400 Capsule may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Inbec 400 Capsule interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
IndinavirLurasidone
Critical
How does the drug interact with Inbec 400 Capsule:
Using Lurasidone together with Inbec 400 Capsule may result in significantly higher Lurasidone blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Lurasidone and Inbec 400 Capsule may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
IndinavirRifampicin
Critical
How does the drug interact with Inbec 400 Capsule:
When Inbec 400 Capsule is taken with Rifampicin, it can reduce the blood levels and effects of Inbec 400 Capsule.

How to manage the interaction:
Although there is an interaction between Inbec 400 Capsule and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
IndinavirNimodipine
Critical
How does the drug interact with Inbec 400 Capsule:
When Nimodipine is taken with Inbec 400 Capsule, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimodipine with Inbec 400 Capsule is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience irregular heart rhythm, swelling. Do not discontinue any medications without a doctor's advice.
IndinavirSilodosin
Critical
How does the drug interact with Inbec 400 Capsule:
Coadministration of Silodosin with Inbec 400 Capsule may significantly increase the blood levels and effects of Silodosin, this may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.

How to manage the interaction:
Taking Silodosin with Inbec 400 Capsule together is not recommended s it can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not discontinue any medications without consulting a doctor.
IndinavirMidazolam
Critical
How does the drug interact with Inbec 400 Capsule:
Inbec 400 Capsule and Midazolam co-administration may considerably enhance Midazolam blood levels and effects.

How to manage the interaction:
Although taking Inbec 400 Capsule and Midazolam together may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • High-fat meals: May reduce the absorption of Inbec 400 Capsule, making it less effective.
  • Grapefruit juice: May increase the levels of Inbec 400 Capsule in the body, raising the risk of side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

Inbec 400 Capsule is used to treat HIV infection.
Inbec 400 Capsule works by decreasing the amount of HIV in the blood. Thereby, Inbec 400 Capsule helps treat HIV infection.
Taking Inbec 400 Capsule with cholesterol-lowering medicines called statins may cause severe muscle pain and weakness. Consult the doctor if you experience severe muscle pain or weakness.
Inbec 400 Capsule may cause kidney stones. Therefore, drink plenty of fluids while on treatment with Inbec 400 Capsule as it helps reduce the chances of forming a kidney stone. Consult the doctor if you develop kidney pain (middle to the lower stomach or back pain) or blood in the urine.
Inbec 400 Capsule does not reduce the risk of passing HIV to others through blood contamination or sexual contact. Therefore, practice safe sex to prevent the risk of transmission.
Consult the doctor before taking sildenafil, tadalafil, or vardenafil with Inbec 400 Capsule as taking them together might increase the risk of side effects like low blood pressure, penile erection lasting more than 4 hours, or visual changes associated with sildenafil, tadalafil, and vardenafil. Seek immediate medical assistance if you have an erection lasting longer than 4 hours.
Didanosine can be taken with Inbec 400 Capsule if prescribed by the doctor. However, maintain a gap of 1 hour between didanosine and Inbec 400 Capsule.
Inbec 400 Capsule may cause hyperglycaemia (high blood sugar) even though you do not have diabetes. Consult the doctor immediately if you notice symptoms of high blood sugar, like frequent urination, extreme thirst, blurred vision, extreme hunger, or weakness. High blood sugar can lead to a serious condition called ketoacidosis if not treated. Symptoms of ketoacidosis include nausea, vomiting, dry mouth, shortness of breath, and decreased consciousness.
It is best to take Inbec 400 Capsule on an empty stomach with water. If you must take it with food, choose a light, low-fat meal, as high-fat foods can prevent your body from absorbing the medicine properly. Talk to your doctor or pharmacist for specific dietary advice.
If you experience sharp side or back pain, or see blood in your urine, contact your doctor immediately. They may need to temporarily pause your treatment or suggest ways to manage the condition. Talk to your doctor before making any changes.
No, Inbec 400 Capsule does not cure HIV, but it helps keep the virus under control so your immune system can stay strong. It is vital to take it daily as part of your overall treatment plan. Talk to your doctor about your long-term health management.
Yes, this medicine can affect how hormonal contraceptives work, making them less reliable at preventing pregnancy. You may need to use an alternative barrier method, such as condoms. Talk to your doctor about the safest birth control options for you.
It is best to avoid or limit alcohol while taking this medicine. Alcohol can increase stress on your liver, which already works hard to process Inbec 400 Capsule, potentially raising the risk of liver damage. Talk to your doctor about safe alcohol consumption.
Keep the capsules in their original bottle with the drying packet inside to protect them from moisture. Avoid leaving them in a hot car or damp luggage. Talk to your pharmacist if you need tips for carrying your medication safely during travel.
Signs of a severe allergic reaction include skin rashes, hives, swelling of the face, lips, or tongue, and difficulty breathing. If you notice any of these symptoms, seek emergency medical care immediately. Talk to your doctor if you have a history of allergies.
If you are pregnant or planning to become pregnant, your doctor will carefully weigh the benefits of controlling HIV infection against any potential risks to your baby before recommending Inbec 400 Capsule. Do not start or stop this medicine during pregnancy without medical advice. Breastfeeding is generally not recommended for people with HIV, as the virus can be passed to the baby through breast milk, even when receiving treatment. Always follow your doctor's recommendations regarding pregnancy and infant feeding.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

A €“ 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
Other Info - INB0001
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