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Composition :
IBRUTINIB-140MG
Manufacturer/Marketer :
Johnson & Johnson Pvt Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Imbruvica 140Mg 120 Capsule:
Taking Carbamazepine and Imbruvica 140Mg 120 Capsule may significantly reduce the blood levels of Imbruvica 140Mg 120 Capsule, which may decrease its effectiveness in treating your condition.
How to manage the interaction:
Although taking Carbamazepine and Imbruvica 140Mg 120 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Carbamazepine and Imbruvica 140Mg 120 Capsule may significantly reduce the blood levels of Imbruvica 140Mg 120 Capsule, which may decrease its effectiveness in treating your condition.
How to manage the interaction:
Although taking Carbamazepine and Imbruvica 140Mg 120 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Imbruvica 140Mg 120 Capsule:
Taking Ticagrelor with Imbruvica 140Mg 120 Capsule can increase the risk or severity of bleeding.
How to manage the interaction:
Taking Imbruvica 140Mg 120 Capsule with Ticagrelor together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Taking Ticagrelor with Imbruvica 140Mg 120 Capsule can increase the risk or severity of bleeding.
How to manage the interaction:
Taking Imbruvica 140Mg 120 Capsule with Ticagrelor together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without consulting a doctor.
IbrutinibLepirudin
Severe
How does the drug interact with Imbruvica 140Mg 120 Capsule:
Co-administration of Imbruvica 140Mg 120 Capsule with Lepirudin can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Imbruvica 140Mg 120 Capsule with Lepirudin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Imbruvica 140Mg 120 Capsule with Lepirudin can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Imbruvica 140Mg 120 Capsule with Lepirudin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Imbruvica 140Mg 120 Capsule:
Co-administration of Deferasirox together with Imbruvica 140Mg 120 Capsule may increase the risk of gastrointestinal ulcers and bleeding.
How to manage the interaction:
Although taking Imbruvica 140Mg 120 Capsule and Deferasirox together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have any of these symptoms, like abdominal pain, bloating, dizziness, lightheadedness, loss of appetite, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools, consult a doctor. Do not discontinue any medications without a doctor's advice.
Co-administration of Deferasirox together with Imbruvica 140Mg 120 Capsule may increase the risk of gastrointestinal ulcers and bleeding.
How to manage the interaction:
Although taking Imbruvica 140Mg 120 Capsule and Deferasirox together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have any of these symptoms, like abdominal pain, bloating, dizziness, lightheadedness, loss of appetite, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools, consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Imbruvica 140Mg 120 Capsule:
Co-administration of Phenobarbital can significantly lower Imbruvica 140Mg 120 Capsule levels in the blood, making the medicine less effective in treating the illness.
How to manage the interaction:
Although taking phenobarbital with Imbruvica 140Mg 120 Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
Co-administration of Phenobarbital can significantly lower Imbruvica 140Mg 120 Capsule levels in the blood, making the medicine less effective in treating the illness.
How to manage the interaction:
Although taking phenobarbital with Imbruvica 140Mg 120 Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Imbruvica 140Mg 120 Capsule:
Co-administration of Mefenamic acid with Imbruvica 140Mg 120 Capsule can increase the risk or severity of bleeding, leading to serious blood loss.
How to manage the interaction:
Taking Mefenamic acid with Imbruvica 140Mg 120 Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Co-administration of Mefenamic acid with Imbruvica 140Mg 120 Capsule can increase the risk or severity of bleeding, leading to serious blood loss.
How to manage the interaction:
Taking Mefenamic acid with Imbruvica 140Mg 120 Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Imbruvica 140Mg 120 Capsule:
Taking Imbruvica 140Mg 120 Capsule with Voriconazole may increase the levels of Imbruvica 140Mg 120 Capsule.
How to manage the interaction:
Although taking Voriconazole and Imbruvica 140Mg 120 Capsule together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fever, shortness of breath, and pain or burning during urination, vomiting, and irregular heart rhythm, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Taking Imbruvica 140Mg 120 Capsule with Voriconazole may increase the levels of Imbruvica 140Mg 120 Capsule.
How to manage the interaction:
Although taking Voriconazole and Imbruvica 140Mg 120 Capsule together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fever, shortness of breath, and pain or burning during urination, vomiting, and irregular heart rhythm, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
IbrutinibOxaprozin
Severe
How does the drug interact with Imbruvica 140Mg 120 Capsule:
Co-administration of Imbruvica 140Mg 120 Capsule with Oxaprozin can increase the risk of bleeding.
How to manage the interaction:
Taking Imbruvica 140Mg 120 Capsule with Oxaprozin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Imbruvica 140Mg 120 Capsule with Oxaprozin can increase the risk of bleeding.
How to manage the interaction:
Taking Imbruvica 140Mg 120 Capsule with Oxaprozin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Imbruvica 140Mg 120 Capsule:
Co-administration of Imbruvica 140Mg 120 Capsule and Rivaroxaban can increase the risk of bleeding problems.
How to manage the interaction:
Co-administration of Imbruvica 140Mg 120 Capsule and Rivaroxaban can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Imbruvica 140Mg 120 Capsule and Rivaroxaban can increase the risk of bleeding problems.
How to manage the interaction:
Co-administration of Imbruvica 140Mg 120 Capsule and Rivaroxaban can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IbrutinibGolimumab
Severe
How does the drug interact with Imbruvica 140Mg 120 Capsule:
Co-administration of Imbruvica 140Mg 120 Capsule and Golimumab can increase the risk of developing serious infections.
How to manage the interaction:
Although there is an interaction, Imbruvica 140Mg 120 Capsule can be taken with Golimumab, if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
Co-administration of Imbruvica 140Mg 120 Capsule and Golimumab can increase the risk of developing serious infections.
How to manage the interaction:
Although there is an interaction, Imbruvica 140Mg 120 Capsule can be taken with Golimumab, if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
Drug-Food Interactions
IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines
Drug-Food Interactions
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IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines
Common Foods to Avoid:
Grapefruit Juice, Grapefruit, St. John’S Wort
How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Imbruvica 140Mg 120 Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Imbruvica 140Mg 120 Capsule.
Grapefruit Juice, Grapefruit, St. John’S Wort
How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Imbruvica 140Mg 120 Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Imbruvica 140Mg 120 Capsule.
Product Substitutes
Alcohol
Consult your doctor
It is not known if alcohol affects Imbruvica 140Mg 120 Capsule. However, avoid consumption of alcohol while on treatment with Imbruvica 140Mg 120 Capsule as it may worsen your condition.
Pregnancy
Unsafe
Ibrutinib belongs to pregnancy category D. Imbruvica 140Mg 120 Capsule should not be used during pregnancy. Use effective contraception and avoid pregnancy during treatment with Imbruvica 140Mg 120 Capsule.
Breast Feeding
Unsafe
Avoid breastfeeding while taking Imbruvica 140Mg 120 Capsule.
Driving
Caution
Imbruvica 140Mg 120 Capsule may cause dizziness and tiredness. Do not drive or operate machinery if you experience any side effects that might lessen your ability to do so.
Liver
Caution
Avoid taking Imbruvica 140Mg 120 Capsule if you have moderate or severe baseline liver impairment. Dose adjustment may be needed in patients with mild liver impairment. If you have a history of liver disease, inform the doctor.
Kidney
Consult your doctor
If you have a history of kidney disease, inform your doctor before taking Imbruvica 140Mg 120 Capsule.
Children
Unsafe
Imbruvica 140Mg 120 Capsule is not recommended for children as safety and effectiveness have not been established.
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