apollo
0
  1. Home
  2. Medicine
  3. Bdbrut Capsule 30's

Offers on medicine orders
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Bdbrut Capsule is used to treat Mantle cell lymphoma, chronic lymphocytic leukaemia, and Waldenstr's macroglobulinaemia. It contains Ibrutinib, which works by blocking Bruton's tyrosine kinase, a protein in the body that helps cancer cells grow and survive. Thereby, it kills and reduces the number of cancer cells. It also slows down the worsening of cancer. Sometimes, Bdbrut Capsule may cause side effects such as nausea, vomiting, diarrhoea, constipation, indigestion, and fatigue.

Read more
rxMedicinePrescription drug

Whats That

tooltip

Composition :

IBRUTINIB-140MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bdbrut Capsule

Bdbrut Capsule belongs to the group of anti-cancer medicines called protein kinase inhibitors used to treat the following blood cancers in adults- mantle cell lymphoma (cancer affecting the lymph nodes), chronic lymphocytic leukaemia (cancer affecting white blood cells and lymph nodes), and waldenström's macroglobulinaemia (cancer affecting white blood cells).

Bdbrut Capsule contains Ibrutinib, which works by blocking Bruton's tyrosine kinase, a protein in the body that helps cancer cells grow and survive. Thereby, it kills and reduces the number of cancer cells. It also slows down the worsening of cancer.

In some cases, Bdbrut Capsule may cause side effects such as nausea, vomiting, diarrhoea, constipation, indigestion, and fatigue. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not take Bdbrut Capsule if you are pregnant or breastfeeding. Consult the doctor immediately if you become pregnant during treatment with Bdbrut Capsule . This medicine is not recommended for children as safety and effectiveness have not been established. Inform the doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Bdbrut Capsule

Bdbrut Capsule is used in the treatment of Mantle cell lymphoma, chronic lymphocytic leukaemia, and Waldenstr's macroglobulinaemia. The detailed uses of Bdbrut Capsule are as follows:<br/>• Mantle cell lymphoma (MCL): Bdbrut Capsule is used in adults who have received at least one prior therapy. It helps slow the progression of this aggressive form of non-Hodgkin lymphoma.<br/>• Chronic lymphocytic leukemia (CLL): Bdbrut Capsule is used for patients with CLL, including those with the 17p deletion, a genetic mutation associated with poor prognosis.<br/>• Waldenstrom’s macroglobulinemia (WM): Bdbrut Capsule is also used to treat this rare type of non-Hodgkin lymphoma that affects B cells and leads to abnormal protein buildup in the blood.<br/>

Directions for Use

• Bdbrut Capsule can be taken with or without food.• It is usually recommended once daily; however, follow your doctor's advice regarding the dosage and duration.• Swallow the capsule as a whole with a glass of water.• Do not break, chew or crush Bdbrut Capsule .

Medicinal Benefits

Bdbrut Capsule belongs to the group of anti-cancer medicines called protein kinase inhibitors used to treat the following blood cancers in adults- mantle cell lymphoma, chronic lymphocytic leukaemia, and waldenström's macroglobulinaemia. This medicine may also be used to treat marginal zone lymphoma (cancer that begins in a type of white blood cells that normally fights infection) and chronic graft vs host disease (a complication of hematopoietic stem-cell transplant). Bdbrut Capsule contains Ibrutinib, which works by blocking Bruton's tyrosine kinase (a protein in the body that helps cancer cells grow and survive). Thereby, it kills and reduces the number of cancer cells. It also slows down the worsening of cancer.

How Bdbrut Capsule Works

Bdbrut Capsule contains Ibrutinib, which works by blocking Bruton's tyrosine kinase, a protein in the body that helps cancer cells grow and survive. Thereby, it kills and reduces the number of cancer cells. It also slows down the worsening of cancer.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Bdbrut Capsule out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Bdbrut Capsule
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Avoid taking raw fruits, nuts and vegetables.
  • Do not share your personal things with others like toothbrushes.
  • Clean the wounds and cuts using soap and water.
  • Wash your hands thoroughly and frequently and maintain hygiene.
  • Get a good quality of sleep.
  • Include lean proteins like skinless poultry and fish.
  • Choose whole grains and low-fat dairy products.
  • Limit intake of fat and oil.
  • Stay hydrated by drinking plenty of water.
  • Restrict heavy sugar intake.
  • Avoid red meat, processed foods, and refined sugar.
  • Eat more fruits and vegetables.
  • Stay hydrated by drinking plenty of water.
  • Avoid rubbing your eyes, which can exacerbate the issue.
  • Lubricate your eyes using artificial tears or eye drops.
  • Wear sunglasses while you are out in the sun to protect your eyes from sun and wind.
  • Avoid irritants like smoke, dust, and strong chemicals.
  • Get enough rest and sleep to help your eyes recover.
  • Using a cold compress may help relieve itching and inflammation associated with conjunctivitis.
  • A warm compress and washing the eyes with water can help with crusting on the eyelids.
  • Avoid wearing contact lens until you feel better; use spectacles instead.
  • Do not rub the eyes.
  • Practise good hand hygiene and avoid touching the eyes to prevent the spread of infection.

What if I have taken an overdose of Bdbrut Capsule

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Bdbrut Capsule or observe any side effects, please go to the emergency department of the closest hospital or nursing home.

Drug Warnings

Do not take Bdbrut Capsule if you are allergic to any of its components, if you are taking St. John's wort (herbal medicine) or if you are pregnant/breastfeeding. Inform the doctor if you have/had unusual bruising or bleeding, irregular heartbeat, heart failure, hepatitis B infection, liver problems, high blood pressure, kidney problems, or if you are due to undergo any surgery. Seek immediate medical attention if you experience symptoms of progressive multifocal leukoencephalopathy, a serious brain infection (trouble thinking, memory loss, sight loss, or difficulty walking), stroke (sudden confusion, numbness or weakness, trouble speaking, sight loss, loss of balance, or sudden severe headache), heart failure (breathlessness, difficulty breathing when lying down, weakness/tiredness, or swelling of the feet, ankles, or legs), rupture of the spleen (left abdominal pain, pain below the left rib cage or at the tip of left shoulder), infection (chills, fever, weakness, body aches, cold, flu symptoms, or confusion), or haemophagocytic lymphohistiocytosis, an inflammatory disorder (fever, bruising, swollen glands, or skin rash).

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions

Login/Sign Up

How does the drug interact with Bdbrut Capsule:
Co-administration of Mefenamic acid with Bdbrut Capsule can increase the risk or severity of bleeding, leading to serious blood loss.

How to manage the interaction:
Taking Mefenamic acid with Bdbrut Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Bdbrut Capsule:
Co-administration of Warfarin with Bdbrut Capsule can increase the risk of bleeding.

How to manage the interaction:
Although taking Bdbrut Capsule and Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Bdbrut Capsule:
Taking Diclofenac with Bdbrut Capsule can increase the risk of bleeding tendencies.

How to manage the interaction:
There may be a possible interaction between Diclofenac and Bdbrut Capsule, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headaches. Do not discontinue any medications without consulting a doctor.
IbrutinibCobicistat
Severe
How does the drug interact with Bdbrut Capsule:
Taking Bdbrut Capsule with Cobicistat may increase the levels of Bdbrut Capsule.

How to manage the interaction:
Although there is a possible interaction between Bdbrut Capsule and Cobicistat, you can take these medicines together if prescribed by a doctor. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, irregular heart rhythm, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Bdbrut Capsule:
Co-administration of Bdbrut Capsule with Fingolimod can increase the risk of serious infections.

How to manage the interaction:
Taking Bdbrut Capsule with Fingolimod together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bdbrut Capsule:
Co-administration of Bdbrut Capsule with Alteplase can increase the risk of bleeding.

How to manage the interaction:
Taking Bdbrut Capsule with Alteplase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bdbrut Capsule:
Co-administration of Bdbrut Capsule with Meloxicam together can increase the risk of bleeding.

How to manage the interaction:
Although taking Meloxicam and Bdbrut Capsule together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IbrutinibDanaparoid
Severe
How does the drug interact with Bdbrut Capsule:
Co-administration of Bdbrut Capsule with Danaparoid can increase the risk of bleeding.

How to manage the interaction:
Taking Bdbrut Capsule with Danaparoid together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bdbrut Capsule:
Co-administration of Bdbrut Capsule with Eptifibatide can increase the risk of bleeding.

How to manage the interaction:
Taking Bdbrut Capsule with Eptifibatide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IbrutinibOxaprozin
Severe
How does the drug interact with Bdbrut Capsule:
Co-administration of Bdbrut Capsule with Oxaprozin can increase the risk of bleeding.

How to manage the interaction:
Taking Bdbrut Capsule with Oxaprozin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines

Drug-Food Interactions

Login/Sign Up

IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines
Common Foods to Avoid:
Grapefruit Juice, Grapefruit, St. John’S Wort

How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Bdbrut Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Bdbrut Capsule.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY
bannner image

Alcohol

Consult your doctor

It is not known if alcohol affects Bdbrut Capsule . However, avoid consumption of alcohol while on treatment with Bdbrut Capsule as it may worsen your condition.

bannner image

Pregnancy

Unsafe

Ibrutinib belongs to pregnancy category D. Bdbrut Capsule should not be used during pregnancy. Use effective contraception and avoid pregnancy during treatment with Bdbrut Capsule .

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding while taking Bdbrut Capsule .

bannner image

Driving

Caution

Bdbrut Capsule may cause dizziness and tiredness. Do not drive or operate machinery if you experience any side effects that might lessen your ability to do so.

bannner image

Liver

Caution

Avoid taking Bdbrut Capsule if you have moderate or severe baseline liver impairment. Dose adjustment may be needed in patients with mild liver impairment. If you have a history of liver disease, inform the doctor.

bannner image

Kidney

Consult your doctor

If you have a history of kidney disease, inform your doctor before taking Bdbrut Capsule .

bannner image

Children

Unsafe

Bdbrut Capsule is not recommended for children as safety and effectiveness have not been established.

Have a query?

FAQs

Bdbrut Capsule is used to treat Mantle cell lymphoma, chronic lymphocytic leukaemia, and Waldenstr’s macroglobulinaemia.

Bdbrut Capsule works by blocking the action of an abnormal protein that helps cancer cells multiply. Thereby, it stops the spread of cancer cells.

Bdbrut Capsule may make you bleed more easily. Therefore, consult the doctor if you are taking blood thinner medicines (heparin, warfarin), NSAIDs (aspirin, ibuprofen, naproxen), or supplements that may increase the risk of bleeding (flaxseed, vitamin E, fish oil).

Bdbrut Capsule may affect the heart, especially if you already have heart diseases like heart failure, heart rhythm problems, diabetes, high blood pressure, or are of advanced age. Consult the doctor instantly if you experience symptoms of heart failure like breathlessness, difficulty breathing when lying down, weakness/tiredness, or swelling of the feet, ankles, or legs.

Country of origin

India

Manufacturer/Marketer address

407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Other Info - BDB0002

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button