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Composition :
IBRUTINIB-140MG
Manufacturer/Marketer :
Natco Pharma Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
IbrutinibAnistreplase
Severe
Drug-Drug Interactions
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How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Clozapine can increase the risk of infections.
How to manage the interaction:
Taking Ibrunat Capsule with Clozapine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Clozapine can increase the risk of infections.
How to manage the interaction:
Taking Ibrunat Capsule with Clozapine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor. Do not stop using any medications without a doctor's advice.
IbrutinibAnistreplase
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Anistreplase can increase the risk of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule with Anistreplase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Anistreplase can increase the risk of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule with Anistreplase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IbrutinibMitotane
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Mitotane may decrease the blood levels of Ibrunat Capsule, which may make Ibrunat Capsule less effective in treating your condition.
How to manage the interaction:
Although taking Ibrunat Capsule and Mitotane together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
Co-administration of Mitotane may decrease the blood levels of Ibrunat Capsule, which may make Ibrunat Capsule less effective in treating your condition.
How to manage the interaction:
Although taking Ibrunat Capsule and Mitotane together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Bivalirudin can increase the risk of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule with Bivalirudin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Bivalirudin can increase the risk of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule with Bivalirudin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IbrutinibBCG vaccine
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of BCG vaccine with Ibrunat Capsule can increase the risk of infection.
How to manage the interaction:
There may be a possibility of interaction between Ibrunat Capsule and BCG vaccine, but it can be taken if prescribed by a doctor. If you notice any signs of infection, it's important to contact the doctor right away. Do not stop using any medications without a doctor's advice.
Co-administration of BCG vaccine with Ibrunat Capsule can increase the risk of infection.
How to manage the interaction:
There may be a possibility of interaction between Ibrunat Capsule and BCG vaccine, but it can be taken if prescribed by a doctor. If you notice any signs of infection, it's important to contact the doctor right away. Do not stop using any medications without a doctor's advice.
IbrutinibEpoprostenol
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Epoprostenol can increase the risk of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule with Epoprostenol together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Epoprostenol can increase the risk of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule with Epoprostenol together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Deferasirox together with Ibrunat Capsule may increase the risk of gastrointestinal ulcers and bleeding.
How to manage the interaction:
Although taking Ibrunat Capsule and Deferasirox together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have any of these symptoms, like abdominal pain, bloating, dizziness, lightheadedness, loss of appetite, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools, consult a doctor. Do not discontinue any medications without a doctor's advice.
Co-administration of Deferasirox together with Ibrunat Capsule may increase the risk of gastrointestinal ulcers and bleeding.
How to manage the interaction:
Although taking Ibrunat Capsule and Deferasirox together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have any of these symptoms, like abdominal pain, bloating, dizziness, lightheadedness, loss of appetite, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools, consult a doctor. Do not discontinue any medications without a doctor's advice.
IbrutinibFenoprofen
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Fenoprofen can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Fenoprofen together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Fenoprofen can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Fenoprofen together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Streptokinase can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Streptokinase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Streptokinase can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Streptokinase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ibrunat Capsule:
Taking Ibrunat Capsule with imatinib may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Taking Ibrunat Capsule with Imatinib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, nausea, vomiting, loss of appetite, fluid retention, swelling, irregular heartbeat, you should consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Taking Ibrunat Capsule with imatinib may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Taking Ibrunat Capsule with Imatinib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, nausea, vomiting, loss of appetite, fluid retention, swelling, irregular heartbeat, you should consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Drug-Food Interactions
IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines
Drug-Food Interactions
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IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines
Common Foods to Avoid:
Grapefruit Juice, Grapefruit, St. John’S Wort
How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Ibrunat Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Ibrunat Capsule.
Grapefruit Juice, Grapefruit, St. John’S Wort
How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Ibrunat Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Ibrunat Capsule.
Product Substitutes
Alcohol
Consult your doctor
It is not known if alcohol affects Ibrunat Capsule . However, avoid consumption of alcohol while on treatment with Ibrunat Capsule as it may worsen your condition.
Pregnancy
Unsafe
Ibrutinib belongs to pregnancy category D. Ibrunat Capsule should not be used during pregnancy. Use effective contraception and avoid pregnancy during treatment with Ibrunat Capsule .
Breast Feeding
Unsafe
Avoid breastfeeding while taking Ibrunat Capsule .
Driving
Caution
Ibrunat Capsule may cause dizziness and tiredness. Do not drive or operate machinery if you experience any side effects that might lessen your ability to do so.
Liver
Caution
Avoid taking Ibrunat Capsule if you have moderate or severe baseline liver impairment. Dose adjustment may be needed in patients with mild liver impairment. If you have a history of liver disease, inform the doctor.
Kidney
Consult your doctor
If you have a history of kidney disease, inform your doctor before taking Ibrunat Capsule .
Children
Unsafe
Ibrunat Capsule is not recommended for children as safety and effectiveness have not been established.
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