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Composition :
IBRUTINIB-140MG
Manufacturer/Marketer :
Natco Pharma Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Dipyridamole can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Dipyridamole together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Dipyridamole can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Dipyridamole together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ibrunat Capsule:
When Ibrunat Capsule is used with Aspirin, the risk of bleeding may increase.
How to manage the interaction:
Although there is a possible interaction between Aspirin and Ibrunat Capsule, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
When Ibrunat Capsule is used with Aspirin, the risk of bleeding may increase.
How to manage the interaction:
Although there is a possible interaction between Aspirin and Ibrunat Capsule, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
IbrutinibLepirudin
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Lepirudin can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Lepirudin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Lepirudin can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Lepirudin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IbrutinibCertolizumab
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule and Certolizumab can increase the risk of developing serious infections.
How to manage the interaction:
Although there is an interaction, Ibrunat Capsule can be taken with Certolizumab, if prescribed by the doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
Co-administration of Ibrunat Capsule and Certolizumab can increase the risk of developing serious infections.
How to manage the interaction:
Although there is an interaction, Ibrunat Capsule can be taken with Certolizumab, if prescribed by the doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule and erythromycin may significantly increase the blood levels of Ibrunat Capsule. This may increase the risk of side effects such as nausea, vomiting, diarrhea, abdominal pain, constipation, and kidney problems.
How to manage the interaction:
Although taking Erythromycin and Ibrunat Capsule together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience paleness, weakness, dizziness, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm consult a doctor immediately. Do not stop using any medications without consulting a doctor.
Co-administration of Ibrunat Capsule and erythromycin may significantly increase the blood levels of Ibrunat Capsule. This may increase the risk of side effects such as nausea, vomiting, diarrhea, abdominal pain, constipation, and kidney problems.
How to manage the interaction:
Although taking Erythromycin and Ibrunat Capsule together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience paleness, weakness, dizziness, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm consult a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Ibrunat Capsule:
When Ibrunat Capsule and Abciximab are taken together, there is a chance that bleeding and haemorrhage risk or severity will rise.
How to manage the interaction:
Taking Abciximab with Ibrunat Capsule together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without a doctor's advice.
When Ibrunat Capsule and Abciximab are taken together, there is a chance that bleeding and haemorrhage risk or severity will rise.
How to manage the interaction:
Taking Abciximab with Ibrunat Capsule together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ibrunat Capsule:
Taking Ibrunat Capsule with imatinib may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Taking Ibrunat Capsule with Imatinib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, nausea, vomiting, loss of appetite, fluid retention, swelling, irregular heartbeat, you should consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Taking Ibrunat Capsule with imatinib may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Taking Ibrunat Capsule with Imatinib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, nausea, vomiting, loss of appetite, fluid retention, swelling, irregular heartbeat, you should consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Atazanavir may significantly raise the blood levels of Ibrunat Capsule.
How to manage the interaction:
Taking Ibrunat Capsule with Atazanavir together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, irregular heart rhythm, consult the doctor. Do not discontinue any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Atazanavir may significantly raise the blood levels of Ibrunat Capsule.
How to manage the interaction:
Taking Ibrunat Capsule with Atazanavir together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, irregular heart rhythm, consult the doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Phenobarbital can significantly lower Ibrunat Capsule levels in the blood, making the medicine less effective in treating the illness.
How to manage the interaction:
Although taking phenobarbital with Ibrunat Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
Co-administration of Phenobarbital can significantly lower Ibrunat Capsule levels in the blood, making the medicine less effective in treating the illness.
How to manage the interaction:
Although taking phenobarbital with Ibrunat Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Ibrunat Capsule:
Taking Ibrunat Capsule with Fondaparinux can increase the risk of bleeding.
How to manage the interaction:
There may be a possibility of interaction between Ibrunat Capsule and Fondaparinux, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Taking Ibrunat Capsule with Fondaparinux can increase the risk of bleeding.
How to manage the interaction:
There may be a possibility of interaction between Ibrunat Capsule and Fondaparinux, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines
Drug-Food Interactions
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IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines
Common Foods to Avoid:
Grapefruit Juice, Grapefruit, St. John’S Wort
How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Ibrunat Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Ibrunat Capsule.
Grapefruit Juice, Grapefruit, St. John’S Wort
How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Ibrunat Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Ibrunat Capsule.
Product Substitutes
Alcohol
Consult your doctor
It is not known if alcohol affects Ibrunat Capsule . However, avoid consumption of alcohol while on treatment with Ibrunat Capsule as it may worsen your condition.
Pregnancy
Unsafe
Ibrutinib belongs to pregnancy category D. Ibrunat Capsule should not be used during pregnancy. Use effective contraception and avoid pregnancy during treatment with Ibrunat Capsule .
Breast Feeding
Unsafe
Avoid breastfeeding while taking Ibrunat Capsule .
Driving
Caution
Ibrunat Capsule may cause dizziness and tiredness. Do not drive or operate machinery if you experience any side effects that might lessen your ability to do so.
Liver
Caution
Avoid taking Ibrunat Capsule if you have moderate or severe baseline liver impairment. Dose adjustment may be needed in patients with mild liver impairment. If you have a history of liver disease, inform the doctor.
Kidney
Consult your doctor
If you have a history of kidney disease, inform your doctor before taking Ibrunat Capsule .
Children
Unsafe
Ibrunat Capsule is not recommended for children as safety and effectiveness have not been established.
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