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Composition :
IBRUTINIB-140MG
Manufacturer/Marketer :
Natco Pharma Ltd
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Ibrunat Capsule:
Taking Ibrunat Capsule with Voriconazole may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Although taking Voriconazole and Ibrunat Capsule together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fever, shortness of breath, and pain or burning during urination, vomiting, and irregular heart rhythm, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Taking Ibrunat Capsule with Voriconazole may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Although taking Voriconazole and Ibrunat Capsule together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fever, shortness of breath, and pain or burning during urination, vomiting, and irregular heart rhythm, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Ibrunat Capsule:
Taking Carbamazepine and Ibrunat Capsule may significantly reduce the blood levels of Ibrunat Capsule, which may decrease its effectiveness in treating your condition.
How to manage the interaction:
Although taking Carbamazepine and Ibrunat Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Carbamazepine and Ibrunat Capsule may significantly reduce the blood levels of Ibrunat Capsule, which may decrease its effectiveness in treating your condition.
How to manage the interaction:
Although taking Carbamazepine and Ibrunat Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
IbrutinibCobicistat
Severe
How does the drug interact with Ibrunat Capsule:
Taking Ibrunat Capsule with Cobicistat may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Although there is a possible interaction between Ibrunat Capsule and Cobicistat, you can take these medicines together if prescribed by a doctor. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, irregular heart rhythm, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Taking Ibrunat Capsule with Cobicistat may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Although there is a possible interaction between Ibrunat Capsule and Cobicistat, you can take these medicines together if prescribed by a doctor. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, irregular heart rhythm, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule and Leflunomide can increase the risk of developing serious infections.
How to manage the interaction:
Although there is an interaction, Ibrunat Capsule can be taken with Leflunomide, if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
Co-administration of Ibrunat Capsule and Leflunomide can increase the risk of developing serious infections.
How to manage the interaction:
Although there is an interaction, Ibrunat Capsule can be taken with Leflunomide, if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Ibrunat Capsule:
Taking Ibrunat Capsule with Tofacitinib may increase the risk of infection.
How to manage the interaction:
Although taking Tofacitinib and Ibrunat Capsule together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
Taking Ibrunat Capsule with Tofacitinib may increase the risk of infection.
How to manage the interaction:
Although taking Tofacitinib and Ibrunat Capsule together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
How does the drug interact with Ibrunat Capsule:
Taking Ibrunat Capsule with Ceritinib may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Although there is an interaction between Ibrunat Capsule and Ceritinib, it can be taken together if prescribed by a doctor. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, irregular heart rhythm, consult a doctor. Do not discontinue any medications without a doctor's advice.
Taking Ibrunat Capsule with Ceritinib may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Although there is an interaction between Ibrunat Capsule and Ceritinib, it can be taken together if prescribed by a doctor. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, irregular heart rhythm, consult a doctor. Do not discontinue any medications without a doctor's advice.
IbrutinibPhenylbutazone
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Phenylbutazone can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Phenylbutazone together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Phenylbutazone can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Phenylbutazone together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ibrunat Capsule:
The combined use of Ibrunat Capsule and Ibuprofen can increase the risk of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule and Ibuprofen together can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
The combined use of Ibrunat Capsule and Ibuprofen can increase the risk of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule and Ibuprofen together can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Phenobarbital can significantly lower Ibrunat Capsule levels in the blood, making the medicine less effective in treating the illness.
How to manage the interaction:
Although taking phenobarbital with Ibrunat Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
Co-administration of Phenobarbital can significantly lower Ibrunat Capsule levels in the blood, making the medicine less effective in treating the illness.
How to manage the interaction:
Although taking phenobarbital with Ibrunat Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Reteplase can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Reteplase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Reteplase can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Reteplase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines
Drug-Food Interactions
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IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines
Common Foods to Avoid:
Grapefruit Juice, Grapefruit, St. John’S Wort
How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Ibrunat Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Ibrunat Capsule.
Grapefruit Juice, Grapefruit, St. John’S Wort
How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Ibrunat Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Ibrunat Capsule.
Product Substitutes
Alcohol
Consult your doctor
It is not known if alcohol affects Ibrunat Capsule . However, avoid consumption of alcohol while on treatment with Ibrunat Capsule as it may worsen your condition.
Pregnancy
Unsafe
Ibrutinib belongs to pregnancy category D. Ibrunat Capsule should not be used during pregnancy. Use effective contraception and avoid pregnancy during treatment with Ibrunat Capsule .
Breast Feeding
Unsafe
Avoid breastfeeding while taking Ibrunat Capsule .
Driving
Caution
Ibrunat Capsule may cause dizziness and tiredness. Do not drive or operate machinery if you experience any side effects that might lessen your ability to do so.
Liver
Caution
Avoid taking Ibrunat Capsule if you have moderate or severe baseline liver impairment. Dose adjustment may be needed in patients with mild liver impairment. If you have a history of liver disease, inform the doctor.
Kidney
Consult your doctor
If you have a history of kidney disease, inform your doctor before taking Ibrunat Capsule .
Children
Unsafe
Ibrunat Capsule is not recommended for children as safety and effectiveness have not been established.
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