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  3. Hyclo 0.05% Eye Drops 5 ml

Hyclo 0.05% Eye Drops 5 ml, Pack of 1
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Hyclo 0.05% Eye Drops 5 ml is used in the treatment of severe keratitis (inflammation of the cornea) in adults. It is also used to treat dry eyes in patients whose condition has not improved with artificial tears. This medicine contains cyclosporine, which helps increase tear production and decrease inflammation (swelling) in the eye. Inform your doctor if you are pregnant or breastfeeding.

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Composition :

CYCLOSPORINE-0.5MG

Manufacturer/Marketer :

Sunways (India) Pvt Ltd

Consume Type :

OPHTHALMIC

Return Policy :

Not Returnable

Expires on or after :

About Hyclo 0.05% Eye Drops 5 ml

Hyclo 0.05% Eye Drops 5 ml is used in the treatment of severe keratitis (inflammation of the cornea) in adults. Also, it is used to treat dry eyes in patients whose condition has not improved with artificial tears.

Hyclo 0.05% Eye Drops 5 ml contains Cyclosporine, which works by increasing tear production and decreasing inflammation (swelling) in the eye. 

In some cases, Hyclo 0.05% Eye Drops 5 ml may cause side effects like irritation, pain, watery eyes, itching, and blurred vision. Consult your doctor if the side effects persist or worsen.

Please tell your doctor if you are allergic to Hyclo 0.05% Eye Drops 5 ml or any other medicines. Consult your doctor if you are pregnant or breastfeeding. Drive only if your vision is clear, as Hyclo 0.05% Eye Drops 5 ml may cause temporary blurred vision immediately after using.

Uses of Hyclo 0.05% Eye Drops 5 ml

Hyclo 0.05% Eye Drops 5 ml is used in the treatment of dry eyes and severe keratitis. The detailed uses of Hyclo 0.05% Eye Drops 5 ml are as follows:

  • Treatment of Keratitis: Hyclo 0.05% Eye Drops 5 ml reduces inflammation in the cornea, helps to relieve discomfort and supports recovery from keratitis symptoms.
  • Dry Eye Relief: Hyclo 0.05% Eye Drops 5 ml is used to provide relief from the symptoms of dry eyes, helping to lubricate and moisten the eye surface.
  • Post-Surgical Recovery: After certain eye surgeries, Hyclo 0.05% Eye Drops 5 ml can aid in the healing process by maintaining eye moisture and reducing discomfort.
  • Improvement of Tear Film Stability: Hyclo 0.05% Eye Drops 5 ml supports the stability of the tear film, which is essential for maintaining clear vision and comfort throughout the day.

Directions for Use

  • Hyclo 0.05% Eye Drops 5 ml is typically used 1-2 times a day, or as prescribed by your healthcare provider, based on the severity of the condition.
  • Tilt your head back, gently pull down your lower eyelid to create a small pocket, and instil the prescribed number of drops into the affected eye. Close your eye and gently press the corner of your eye near the nose for 1-2 minutes to prevent the drops from draining out.
  • Avoid touching the dropper to any surface, including your eyes, to prevent contamination.

Medicinal Benefits

  • Hyclo 0.05% Eye Drops 5 ml helps stimulate the eye's natural ability to produce tears, especially in patients with chronic dry eye disease.
  • It provides long-term relief for patients who do not respond adequately to artificial tears.
  • Hyclo 0.05% Eye Drops 5 ml decreases inflammation associated with dry eye syndrome and other ocular surface diseases.
  • It helps restore a healthy tear film and improves comfort and vision.
  • Hyclo 0.05% Eye Drops 5 ml is used in managing severe cases of keratitis (inflammation of the cornea), particularly when caused by underlying immune-mediated conditions.
  • It helps protect the cornea from damage due to dryness or inflammatory processes.
  • It promotes healing of the eye's surface by maintaining adequate moisture and reducing immune-related damage.
  • Also, supports recovery and maintenance of a stable tear film for better visual function.

How Hyclo 0.05% Eye Drops 5 ml Works

Hyclo 0.05% Eye Drops 5 ml contains Cyclosporine, which works by increasing tear production and decreasing inflammation (swelling) in the eye.

Storage

• Store in a cool and dry place away from sunlight.• Keep Hyclo 0.05% Eye Drops 5 ml out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Hyclo 0.05% Eye Drops 5 ml
  • To the affected part, apply warm compresses to get a temporary relief.
  • Rinse your eye carefully with clean water and try to blow any dust particle that could have entered.
  • Take over the counter medication to lubricate your eye or if there is pain due to allergy to soothe the eye.
  • If there is persistent pain in your eye, consult your doctor and follow the medication immediately.
  • Eat a healthy, well-balanced diet full of vitamins, minerals, and omega-3 fatty acids to help maintain eye health.
  • Wear UV-protecting sunglasses when you are outside or in bright light.
  • Avoid touching or rubbing your eyes it may increase irritation.
  • Seek medical care if you are experiencing extreme eye pain or discomfort.
  • Your doctor might recommend eye drops to treat dry eyes, reduce inflammation, or stop irritation.
  • Use a cold, moist towel to relieve inflammation and discomfort.
  • Refrain from rubbing or touching the affected eyelid to avoid worsening the irritation.
  • Avoid allergens like pollen or pet dander that may trigger eyelid erythema.
  • Gently wash the eyelid with mild soap and water to prevent infection.
  • Drink lots of water to keep your skin and eyes moisturized.
  • Inform your doctor if you experience severe symptoms like intense pain, vision changes, or increased sensitivity to light.
  • Avoid rubbing your eyes, which can exacerbate the issue.
  • Lubricate your eyes using artificial tears or eye drops.
  • Wear sunglasses while you are out in the sun to protect your eyes from sun and wind.
  • Avoid irritants like smoke, dust, and strong chemicals.
  • Get enough rest and sleep to help your eyes recover.
  • Stay hydrated by drinking plenty of water.
  • Get plenty of rest to help your eyes recover.
  • Eat a balanced diet low in fat and rich in fruits, vegetables, and whole grains.
  • Limit spicy and seasoned foods that can irritate your eyes.
  • Avoid seafood, which can trigger allergies or infections that worsen red eye symptoms.
  • Talk to the doctor if you notice any visual disturbances.
  • Do not drive or operate machinery unless you have a clear vision.
  • Lubricate the eyes and use a warm compress to gently massage the eyes.
  • Keep your eyes protected from harmful sun rays by wearing sunglasses and a hat.
  • Rest well and eat a balanced diet.
  • Use a humidifier and increase fluid intake.
  • Eat a healthy, low-fat diet rich in whole grains, fruits, and vegetables.
  • Drink plenty of water to stay hydrated.
  • Get adequate sleep and avoid direct sunlight.
  • Follow a low-salt diet to minimize fluid retention.
  • Apply a cold compress to reduce inflammation and soothe affected areas.

What if I have taken an overdose of Hyclo 0.05% Eye Drops 5 ml

An overdose of Hyclo 0.05% Eye Drops 5 ml is not expected to be dangerous. However, if an overdose is suspected, seek medical help.

Drug Warnings

  • Please tell your doctor if you are allergic to Hyclo 0.05% Eye Drops 5 ml or any other medicines.
  • If you are pregnant or breastfeeding, consult a doctor.
  • Avoid using Hyclo 0.05% Eye Drops 5 ml while you are wearing contact lenses.
  • Drive only if your vision is clear, as Hyclo 0.05% Eye Drops 5 ml may cause temporary blurred vision immediately after use.
  • If you have or had an eye infection, inform your doctor before using Hyclo 0.05% Eye Drops 5 ml.
  • You are recommended to maintain a time gap of 15 minutes between using other eye medicines and Hyclo 0.05% Eye Drops 5 ml.
  • Discard the bottle after 4 weeks of first opening to prevent infections.

Drug-Drug Interactions

verifiedApollotooltip
CiclosporinSimvastatin
Critical
CiclosporinBosentan
Critical

Drug-Drug Interactions

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CiclosporinSimvastatin
Critical
How does the drug interact with Hyclo 0.05% Eye Drops 5 ml:
Combining Hyclo 0.05% Eye Drops 5 ml and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Hyclo 0.05% Eye Drops 5 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBosentan
Critical
How does the drug interact with Hyclo 0.05% Eye Drops 5 ml:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Hyclo 0.05% Eye Drops 5 ml with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinCidofovir
Critical
How does the drug interact with Hyclo 0.05% Eye Drops 5 ml:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Hyclo 0.05% Eye Drops 5 ml with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinPitavastatin
Critical
How does the drug interact with Hyclo 0.05% Eye Drops 5 ml:
Coadministration of pitavastatin with Hyclo 0.05% Eye Drops 5 ml may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Hyclo 0.05% Eye Drops 5 ml is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinBaricitinib
Critical
How does the drug interact with Hyclo 0.05% Eye Drops 5 ml:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Hyclo 0.05% Eye Drops 5 ml with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinCarbamazepine
Severe
How does the drug interact with Hyclo 0.05% Eye Drops 5 ml:
Taking carbamazepine and Hyclo 0.05% Eye Drops 5 ml may decrease the effects of Hyclo 0.05% Eye Drops 5 ml.

How to manage the interaction:
Although taking carbamazepine and Hyclo 0.05% Eye Drops 5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinAdefovir dipivoxil
Severe
How does the drug interact with Hyclo 0.05% Eye Drops 5 ml:
Coadministration of adefovir dipivoxil with Hyclo 0.05% Eye Drops 5 ml may significantly increase the negative effect of kidneys.

How to manage the interaction:
Although there is a possible interaction between adefovir dipivoxil and Hyclo 0.05% Eye Drops 5 ml, they can be taken together if your doctor has prescribed them. However, contact your doctor if experience any symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinSaquinavir
Severe
How does the drug interact with Hyclo 0.05% Eye Drops 5 ml:
Taking Hyclo 0.05% Eye Drops 5 ml with saquinavir may increase the blood levels and effects of Hyclo 0.05% Eye Drops 5 ml.

How to manage the interaction:
Taking saquinavir with Hyclo 0.05% Eye Drops 5 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of nausea, vomiting, diarrhea, abdominal pain, dizziness, weakness, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinKetoconazole
Severe
How does the drug interact with Hyclo 0.05% Eye Drops 5 ml:
Co-administration of ketoconazole with Hyclo 0.05% Eye Drops 5 ml may increases the blood levels of Hyclo 0.05% Eye Drops 5 ml.

How to manage the interaction:
Although taking ketoconazole and Hyclo 0.05% Eye Drops 5 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if your condition worsens or you encounter more adverse effects, such as nausea, vomiting, diarrhea, abdominal discomfort, exhaustion, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, or increased or decreased urine, consult a doctor. Do not discontinue any medication without consulting a doctor.
CiclosporinFosamprenavir
Severe
How does the drug interact with Hyclo 0.05% Eye Drops 5 ml:
Taking fosamprenavir and Hyclo 0.05% Eye Drops 5 ml may increases the blood levels and effects of Hyclo 0.05% Eye Drops 5 ml.

How to manage the interaction:
There may be a possibility of interaction between fosamprenavir and Hyclo 0.05% Eye Drops 5 ml, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as diarrhea or stomach pain, feeling dizzy or tired, having a headache or fits, having a fever or sore throat, or bleeding or bruising. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Use a humidifier in your room to increase moisture and avoid dry conditions.
  • Limit the time you spend in front of the television or computer.
  • If dry eyes are caused by environmental factors, wear protective eyewear during outdoor activities when it’s windy and avoid exposure to cigarette smoke.
  • Limit wearing contact lenses and use soft contact lenses if you have dry eyes, as they are moist and allow the eye to breathe better than hard contact lenses.
  • Take omega-3 fatty acid supplements as they may be helpful in treating dry eyes. 

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Hyclo 0.05% Eye Drops 5 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

The interaction of alcohol with Hyclo 0.05% Eye Drops 5 ml is unknown. Please consult a doctor before consuming alcohol with Hyclo 0.05% Eye Drops 5 ml.

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Pregnancy

Consult your doctor

Consult your doctor before using Hyclo 0.05% Eye Drops 5 ml if you are pregnant. Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Breast Feeding

Consult your doctor

If you are breastfeeding, consult your doctor before using Hyclo 0.05% Eye Drops 5 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Driving

Caution

Hyclo 0.05% Eye Drops 5 ml may cause temporary blurred vision immediately after applying. Therefore, wait until your vision is clear before driving or operating machinery.

bannner image

Liver

Consult your doctor

If you have any concerns regarding the use of Hyclo 0.05% Eye Drops 5 ml in patients with liver problems, please consult your doctor.

bannner image

Kidney

Consult your doctor

If you have any concerns regarding the use of Hyclo 0.05% Eye Drops 5 ml in patients with kidney problems, please consult your doctor.

bannner image

Children

Caution

Hyclo 0.05% Eye Drops 5 ml should be used in children only if it is advised by a doctor. It is not recommended for use in children less than four years.

Have a query?

FAQs

Hyclo 0.05% Eye Drops 5 ml is used in the treatment of severe keratitis (inflammation of the cornea) in adults. Also, it is used to treat dry eyes in patients whose condition has not improved with artificial tears.

Hyclo 0.05% Eye Drops 5 ml contains Cyclosporine, which works by increasing tear production and decreasing inflammation (swelling) in the eye. Thereby, it provides a soothing effect and relieves irritation and dryness caused by decreased tear flow.

You are recommended to use Hyclo 0.05% Eye Drops 5 ml after 15 minutes of using other eye medications only if advised by your doctor. Therefore, inform your doctor if you are using any other medicines before using Hyclo 0.05% Eye Drops 5 ml.

Hyclo 0.05% Eye Drops 5 ml may cause temporary blurred vision immediately after applying. Therefore, you are recommended to wait until your vision is clear before driving or operating machinery.

You are recommended to avoid wearing contact lenses while using Hyclo 0.05% Eye Drops 5 ml as it may cause eye irritation. Therefore, you are advised to remove contact lenses before applying Hyclo 0.05% Eye Drops 5 ml and reinsert after 15 minutes of using Hyclo 0.05% Eye Drops 5 ml. Also, inform your doctor if you experience pain, stinging or abnormal sensation in the eye after using Hyclo 0.05% Eye Drops 5 ml.

You are recommended to discuss with your doctor before using eye drops containing steroids with Hyclo 0.05% Eye Drops 5 ml as there is a risk of side effects if both medicines are used simultaneously.

Country of origin

India

Manufacturer/Marketer address

1002-1003, 10th Floor, Windfall, Sahar Plaza, J.B.Nagar, Andheri-Kurla Road, Andheri (East), Mumbai-400059. Maharashtra, India.
Other Info - HYC0047

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 7, 2025 | 11:39 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/product/6937/pil#gref
  2. https://www.ema.europa.eu/en/documents/product-information/verkazia-epar-product-information_en.pdf
  3. https://www.nottsapc.nhs.uk/media/1058/ciclosporin-info-sheet.pdf

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