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Histacalamine Lotion 125 ml is used to treat allergies & skin infections. It contains Chlorpheniramine and Calamine which work by blocking the action of histamine, a substance responsible for causing allergic reactions. In some cases, this medicine may cause side effects such as irritation or burning sensation at the application site. It is for external use only.

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Written By Dr. Aneela S , M Pharmacy, PhD
Reviewed By Dr. Syed Akram , MBBS, MD
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More about the Product

Manufacturer/Marketer :

Pasteur Laboratories Pvt Ltd

Consume Type :

Topical

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Histacalamine Lotion 125 ml

Histacalamine Lotion 125 ml is a topical skin preparation used to relieve itching, irritation, and discomfort caused by minor skin conditions, insect bites, allergic rashes, and prickly heat. It works by soothing the skin and reducing the effects of allergic reactions, helping relieve itching, redness, and irritation while promoting comfort during healing.

Histacalamine Lotion 125 ml is applied directly to the skin, typically three to four times a day or as recommended by your healthcare provider. For best results, it should be used consistently at the first sign of itching or discomfort. Make sure your skin is clean and dry before each application, and wear loose-fitting cotton clothing to prevent further irritation.

While this medication is generally safe for surface-level use, some people may experience mild, temporary skin burning, dryness, or redness at the application site. If you develop a severe rash, worsening itching, or signs of an allergic reaction, stop using the product and talk to your doctor or pharmacist immediately.

Do not use this medicine if you have a known allergy to any of its active ingredients. Before you start using Histacalamine Lotion 125 ml, talk to your doctor if you have deep skin wounds, open sores, or severe skin infections, as topical medicines should not be applied to broken skin.

Using other topical creams or ointments at the same time may interfere with how this medicine works. If you are pregnant, breastfeeding, or managing skin conditions in elderly family members, consult your doctor or pharmacist before application to ensure safe use.

Uses of Histacalamine Lotion 125 ml

Histacalamine Lotion 125 ml is used to relieve itching, irritation, and discomfort associated with various skin conditions. The detailed uses of Histacalamine Lotion 125 ml are as follows:

  • Skin itching (pruritus): Histacalamine Lotion 125 ml calms sensitive skin nerves to reduce the urge to scratch irritated areas.
  • Insect bites and stings: It helps reduce local swelling, redness, and sharp itching caused by mosquito, bee, or other insect bites.
  • Sunburn: It provides a cooling physical sensation that soothes inflamed, overheated skin after sun exposure.

Key Benefits

Histacalamine Lotion 125 ml helps provide fast relief from itching, irritation, and discomfort caused by minor skin conditions. It soothes the affected area, cools the skin, and helps reduce the urge to scratch. The detailed benefits of Histacalamine Lotion 125 ml include:

  • Provides Fast Itch Relief: Helps quickly relieve itching, irritation, and discomfort caused by allergies, insect bites, and minor skin rashes.
  • Soothes and Cools the Skin: Produces a cooling effect that helps calm inflamed, irritated, or sunburned skin.
  • Reduces Redness and Irritation: Helps relieve mild redness, swelling, and skin discomfort associated with allergic skin reactions.
  • Helps Protect the Skin: Reduces scratching, which may help prevent further skin damage and lower the risk of secondary skin infections.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Take a small amount of Histacalamine Lotion 125 ml on the fingertip and apply it as a thin layer on the clean and dry affected area as recommended by your doctor.
  • Avoid contact of the Histacalamine Lotion 125 ml with the nose or eyes. In case of accidental contact with these areas, rinse with water thoroughly. Wash your hands before and after using Histacalamine Lotion 125 ml if your hands are not the affected area to prevent the spread of infection.

How Histacalamine Lotion 125 ml Works

Histacalamine Lotion 125 ml contains two active ingredients, Calamine and Chlorpheniramine, that work together to provide symptomatic relief from itching, redness, and skin irritation caused by minor skin conditions and allergic reactions. Calamine is a mild skin protectant and astringent that soothes and cools irritated skin. As it dries on the skin, it helps relieve itching and discomfort while drying up oozing from minor skin rashes. Chlorpheniramine is an antihistamine included to help relieve itching associated with allergic skin reactions. When applied topically, it is intended to provide symptomatic relief at the application site. Because systemic absorption is minimal when used as directed, its effects are primarily limited to the treated area.
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Alcohol

Safe if prescribed

No interactions were found or established.

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Pregnancy

Caution

Histacalamine Lotion 125 ml contains Chlorpheniramine, a category B pregnancy drug and is given to pregnant women only if the doctor thinks it is essential. Please consult a doctor if you are pregnant.

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Breast Feeding

Caution

Histacalamine Lotion 125 ml is known to pass through breast milk. So, apply it only if prescribed by a doctor.

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Driving

Safe if prescribed

Histacalamine Lotion 125 ml does not interfere ability to drive or operate machinery.

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Liver

Caution

Take Histacalamine Lotion 125 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Histacalamine Lotion 125 ml with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Histacalamine Lotion 125 ml is not recommended for children below the age of 2 years.

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Heart

Consult your doctor

Inform your doctor if you have any existing heart disease. Your doctor will prescribe this medicine only if the potential benefits outweigh the risks.

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Geriatrics

Consult your doctor

Histacalamine Lotion 125 ml should be used in elderly patients only if prescribed by a doctor. Seek medical advice before using Histacalamine Lotion 125 ml.

What if I have taken an overdose of Histacalamine Lotion 125 ml

Because this is a topical medicine, overdose from skin application is highly unlikely. However, if the medicine is accidentally swallowed, seek immediate medical attention immediately.

Diet & Lifestyle Advise

  • Wear Loose, Breathable Clothing: Choose loose-fitting cotton clothing to minimise friction and reduce sweating, which can worsen skin itching.
  • Use Lukewarm Water: Bathe or shower with lukewarm water instead of hot water, as hot water can dry out the skin and trigger itching.
  • Keep Your Fingernails Short: Trim and keep your fingernails clean to help prevent skin damage or infection if you scratch the affected area.
  • Stay Well Hydrated: Drink plenty of water throughout the day to support your skin's natural moisture and healing process.
  • Avoid Allergy Triggers: Identify and avoid personal triggers, such as harsh detergents, synthetic fabrics, or heavily fragranced soaps, that may worsen your symptoms.
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How Soon It Starts Working

The time required for Histacalamine Lotion 125 ml to start to work: Histacalamine Lotion 125 ml ideally shows its action within 30 minutes after administration. The time for which the effects of Histacalamine Lotion 125 ml last: The effect of Histacalamine Lotion 125 ml lasts for 4 to 6 hours.

What if you forget to take Histacalamine Lotion 125 ml

If you forget to apply a dose, apply it as soon as you remember. If it is almost time for your next scheduled application, skip the missed one and continue with your regular schedule. Do not apply a double layer of the medicine to make up for a missed application.

Storage

• Store Histacalamine Lotion 125 ml at room temperature (between 15°C to 30°C).

Drug Warnings

  • Avoid Contact with Sensitive Areas: Keep the medicine away from your eyes, nose, mouth, and genital area. If accidental contact occurs, rinse thoroughly with water.
  • Do Not Cover the Treated Area: Avoid using tight bandages, plastic wraps, or airtight dressings unless directed by your doctor.
  • Check the Product Before Use: Do not use the lotion if it has an unusual odor or if severe separation does not resolve after shaking.
  • Do Not Apply to Broken Skin: Avoid applying Histacalamine Lotion 125 ml to open wounds, broken, or severely inflamed skin unless advised by your doctor, as this may increase the absorption of chlorpheniramine and raise the risk of unwanted side effects.
  • Avoid Prolonged Use: Prolonged or repeated use of topical antihistamines may rarely cause contact sensitisation or allergic contact dermatitis. Stop using Histacalamine Lotion 125 ml and consult your doctor if you develop worsening redness, itching, swelling, rash, or blistering at the application site.

verifiedApollotooltip

Certain topical products may interact with Histacalamine Lotion 125 ml or increase the risk of skin irritation. Important interactions include: 

  • Other Topical Medications (e.g., Steroid Creams or Antihistamine Preparations): Using these on the same area of skin may affect how Histacalamine Lotion 125 ml works or increase the risk of skin irritation. Consult your doctor before using multiple topical treatments together.
  • Other Zinc-Containing Skin Preparations: Applying multiple zinc-containing products to the same area may increase skin dryness or irritation. Use them together only if advised by your doctor.

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verifiedApollotooltip

No clinically significant food interactions are known with Histacalamine Lotion 125 ml when used as directed.

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Habit Forming

No

Therapeutic Class

[ANTIHISTAMINE]

FAQs

Histacalamine Lotion 125 ml is for external use only. Apply a thin layer to the affected area exactly as directed. Avoid contact with the eyes, mouth, and other mucous membranes. If accidental eye contact occurs, rinse immediately with plenty of clean water for several minutes. If irritation, pain, or vision changes persist, seek medical advice.
No, you should not apply Histacalamine Lotion 125 ml to open wounds, deep cuts, or severely broken skin, as this can cause irritation and unwanted absorption into the bloodstream. Talk to your doctor for appropriate wound care advice.
Because Histacalamine Lotion 125 ml is applied topically to the skin, very little chlorpheniramine enters your bloodstream. It is highly unlikely to cause drowsiness when used as directed. Talk to your doctor if you experience unusual sleepiness.
You should allow Histacalamine Lotion 125 ml to dry completely on your skin first. Once it is dry, you can apply makeup, but it is best to talk to your doctor or pharmacist to ensure you are not irritating the skin further.
Although topical absorption of these ingredients is very low, you should always consult your doctor before using Histacalamine Lotion 125 ml if you are pregnant or planning to become pregnant.
You should not use Histacalamine Lotion 125 ml on infants or for diaper rash without consulting a paediatrician first, as infant skin is highly sensitive. Talk to your doctor for safe paediatric alternatives.
No, you should leave the treated area open to the air. Covering it with tight bandages or plastic wrap can increase absorption and cause unwanted side effects. Talk to your doctor if you feel a protective cover is necessary.
Histacalamine Lotion 125 ml may help relieve itching and irritation associated with mild eczema or chickenpox rash, but it does not treat the underlying cause of these conditions. Avoid applying it to broken, infected, or severely inflamed skin unless advised by your doctor. If symptoms are severe, persistent, or worsen, consult a healthcare professional for appropriate treatment.
Calamine is a skin protectant and antipruritic (anti-itch agent) with mild astringent properties. It helps soothe irritated skin, provides a cooling sensation as it dries, and relieves itching and minor skin irritation while helping to dry up oozing from skin rashes.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

2A, Bidhan Sarani, Kolkata - 700 006
Other Info - HIS0240
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