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Grenil Paed Susp is used to provide symptomatic relief from childhood migraine, tension headaches and fever associated with nausea and vomiting. It contains Domperidone and Paracetamol. Domperidone works by blocking dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it helps to prevent nausea, and vomiting. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Grenil Paed Susp

Grenil Paed Susp is a liquid medicine specially prepared for children to help relieve pain, bring down a high temperature, and stop feelings of sickness. It is commonly prescribed to treat conditions where a fever or body aches are accompanied by an upset stomach, nausea, or vomiting. By addressing these symptoms together, it helps your child feel more comfortable and recover quietly.

Your doctor will tell you exactly how often to give this medicine, but it is typically used on an as-needed basis when symptoms arise. For the best results in settling a sick stomach, it is usually best to give this medicine shortly before meals. Alongside this treatment, keeping your child in a quiet, cool room and offering small, frequent sips of water can greatly help their recovery.

Most children tolerate this medicine well, though some may experience mild side effects like a dry mouth, drowsiness, or a temporary upset stomach. These effects are usually mild and go away on their own. However, if you notice any unusual signs like a skin rash, swelling, or extreme sleepiness, stop giving the medicine and talk to your doctor right away.

Before starting this medicine, tell your doctor if your child has any history of liver, kidney, or heart conditions. Do not give this medicine if your child has a known heart rhythm issue, severe liver disease, or any bleeding or blockage in their stomach or intestines. Extreme caution or complete avoidance is required in neonates and infants under 1 year of age, as domperidone carries specific risks in very young children.

It is crucial to avoid giving this medicine alongside other medicines that treat pain, fever, or cold symptoms, as doing so can cause accidental liver damage. Although this is a paediatric formulation, if it is ever considered for older age groups, pregnant or breastfeeding individuals must consult their doctor before use.

Uses of Grenil Paed Susp

Grenil Paed Susp is used to relieve pain and fever along with nausea or vomiting in children. The detailed uses of Grenil Paed Susp are as follows:

  • Fever with nausea or vomiting: Helps cool down your child's body temperature while settling their stomach to prevent vomiting.
  • Pain accompanied by sickness: Relieves mild-to-moderate physical discomforts, such as headaches or teething pain, while keeping nausea under control.
  • Post-vaccination discomfort: Soothes mild fever and body aches that occur after childhood immunisations (note: paediatric guidelines recommend using this medicine only after symptoms actually develop, rather than as a routine preventive dose before vaccination).

Key Benefits

Grenil Paed Susp is used to provide symptomatic relief from childhood migraine, tension headaches and fever associated with nausea and vomiting. Grenil Paed Susp contains Domperidone and Paracetamol. Domperidone works by blocking dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it helps to prevent nausea and vomiting. Also, Domperidone acts as a prokinetic agent that increases the movement of the stomach and upper gastrointestinal tract, allowing food to move more quickly through the stomach and into the intestine. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever.

Directions for Use

  • Grenil Paed Susp can be given on an empty stomach, at least 30 minutes before a meal.
  • Follow your doctor’s instructions on the dosage and timing of this medication, or use it as per the labelled instructions.
  • Shake the bottle well before each use.
  • Give the prescribed dose to your child by mouth using the measuring cup provided with the pack.
  • Avoid using regular household spoons, as they may not measure the dose correctly.

How Grenil Paed Susp Works

Grenil Paed Susp contains two active ingredients, domperidone and paracetamol, which work together to relieve nausea and vomiting, reduce fever, and ease pain. Domperidone acts peripherally in the digestive tract and targets the chemoreceptor trigger zone (an area outside the blood-brain barrier) to suppress nausea signals and speed up stomach emptying. Paracetamol acts in the central nervous system to reduce pain signals and regulate the body's internal thermostat, lowering fever and easing body aches. Most children begin to feel symptom relief within 30 to 60 minutes after taking the dose.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

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Liver

Consult your doctor

If your child has liver disease/condition, please inform your doctor.

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Kidney

Consult your doctor

If your child has kidney disease/condition, please inform your doctor.

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Children

Safe if prescribed

Use Grenil Paed Susp for children as advised by the doctor.

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Heart

Caution

Grenil Paed Susp should not be given to a child with heart problems without medical advice, as Domperidone may cause serious cardiac side effects. Always consult a pediatrician or cardiologist before use to ensure safety.

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Geriatrics

Not applicable

Grenil Paed Susp is specifically for children use and is not meant for geriatric patients.

What if I have taken an overdose of Grenil Paed Susp

If you suspect your child has taken too much of this medicine, seek immediate medical attention. Even if your child seems perfectly fine, an overdose can cause serious liver damage that may not show symptoms until days later.

Diet & Lifestyle Advise

  • Hydration: Offer your child frequent, small sips of water, clear broths, or oral rehydration solutions to replace fluids lost from vomiting or sweating.
  • Easy-to-Digest Foods: Once the stomach settles, offer bland, easy-to-digest foods like crackers, toast, rice, or applesauce. Avoid giving greasy, fried, or highly sugary foods.
  • Comfortable Clothing: Keep your child dressed in lightweight, breathable clothing and keep the room at a comfortable, cool temperature to help manage fever naturally.
  • Rest: Ensure your child gets plenty of quiet bed rest to help their body recover.
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How Soon It Starts Working

The time required for Grenil Paed Susp to start to work: Grenil Paed Susp ideally shows its action within 1 hour after administration. The time for which the effects of Grenil Paed Susp last: The effect of Grenil Paed Susp lasts for 6 hours.

What if you forget to take Grenil Paed Susp

If you miss a dose, give it as soon as you remember, unless it is almost time for the next scheduled dose. In that case, skip the missed dose and continue with the normal schedule. Never give a double dose to make up for a missed one.

Storage

•Store the bottle at room temperature, ideally below 30°C.

Drug Warnings

  • Check the Expiry Date: Always check the expiry date printed on the bottle before giving the medicine to your child.
  • Check the Liquid: Visually check the liquid inside the bottle; do not use it if it looks clumpy, has changed colour, or if particles do not dissolve after a thorough shake.
  • Avoid Other Medicines: Never give this medicine alongside any other over-the-counter cough, cold, pain, or fever medicines without checking with a professional, as many contain similar ingredients that could cause an accidental overdose.
  • Monitor Symptoms: Seek immediate medical care if your child's condition suddenly worsens, if they show signs of severe dehydration (such as no wet nappies or lack of tears), if fever lasts for more than 3 days, or if vomiting continues for more than 24 hours.

Drug-Drug Interactions

verifiedApollotooltip
  • Other pain and fever relievers: Taking other pain or fever medicines at the same time can greatly increase the risk of severe liver damage.
  • Certain antibiotics and antifungals: Some of these medicines can interact with the stomach-settling component, which may increase the risk of irregular heartbeats.
  • Medicines that affect stomach movement: Medicines that slow down or speed up the gut may change how well this medicine is absorbed.

Drug-Drug Interactions

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How does the drug interact with Grenil Paed Susp 60Ml:
Co-administration of Leflunomide with Grenil Paed Susp 60Ml may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction of Leflunomide with Grenil Paed Susp 60Ml, it can be taken if prescribed by a doctor. However, if you experience fever, vomiting, stomach pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Grenil Paed Susp 60Ml:
Co-administration of Teriflunomide and Grenil Paed Susp 60Ml may increase the risk or severity of liver problems.

How to manage the interaction:
Taking Teriflunomide and Grenil Paed Susp 60Ml may result in an interaction, it can be taken if a doctor has advised it. Contact your doctor if you experience vomiting, stomach pain, or yellowing of eyes and skin. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Grenil Paed Susp 60Ml:
Co-administration of Lomitapide and Grenil Paed Susp 60Ml may increase the risk of severity of liver injury.

How to manage the interaction:
Although Lomitapide and Grenil Paed Susp 60Ml can lead to an interaction, it can taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Grenil Paed Susp 60Ml:
Coadministration of Cisapride with Grenil Paed Susp 60Ml can increase the blood levels of Domperidone.

How to manage the interaction:
There may be a possibility of interaction of Cisapride with Grenil Paed Susp 60Ml, it can be taken when prescribed by a doctor. If you experience dizziness, chest pain, shortness of breath, or palpitations, contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Grenil Paed Susp 60Ml:
Coadministration of Ketoconazole with Grenil Paed Susp 60Ml can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Ketoconazole with Grenil Paed Susp 60Ml can lead to an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, shortness of breath, or palpitations, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Grenil Paed Susp 60Ml:
Co-administration of Mipomersen and Grenil Paed Susp 60Ml may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possible interaction between Mipomersen and Grenil Paed Susp 60Ml, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Grenil Paed Susp 60Ml:
Coadministration of Nefazodone and Grenil Paed Susp 60Ml can increase the blood levels of Domperidone.

How to manage the interaction:
There may be a possible interaction of Nefazodone and Grenil Paed Susp 60Ml, it can be taken if prescribed by a doctor. If you experience chest pain, palpitations, constipation, or burning urination, contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Grenil Paed Susp 60Ml:
Coadministration of Clarithromycin with Grenil Paed Susp 60Ml can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction of Clarithromycin with Grenil Paed Susp 60Ml, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Grenil Paed Susp 60Ml:
Coadministration of Methadone and Grenil Paed Susp 60Ml can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although Methadone and Grenil Paed Susp 60Ml can lead to an interaction, it can be taken if your doctor has advised it. If you experience lightheadedness, shortness of breath, or palpitation, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Grenil Paed Susp 60Ml:
Coadministration of Toremifene and Grenil Paed Susp 60Ml can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although Toremifene and Grenil Paed Susp 60Ml can cause an interaction, it can be taken if a doctor has advised it. If you experience lightheadedness, shortness of breath, or palpitation, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Food: Taking this medicine with meals may slightly delay how quickly it starts to relieve pain and fever, though it can still be given with food to prevent stomach upset.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIMIGRAINE AGENTS]

FAQs

Grenil Paed Susp is used to provide symptomatic relief from childhood migraine, tension headaches and fever associated with nausea and vomiting.
Grenil Paed Susp contains Domperidone and Paracetamol. Domperidone works by blocking dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone—CTZ) in the brain. Thus, it helps to prevent nausea and vomiting. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever.
Grenil Paed Susp may cause dry mouth as a common side effect. However, to avoid such side effects, make sure your child drinks plenty of water, regularly rinse their mouth, practice good oral hygiene and let them suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.
You are advised not to stop using Grenil Paed Susp for your child without consulting a doctor as it may worsen the condition or cause recurring symptoms. Therefore, use Grenil Paed Susp for as long as your doctor has prescribed it, and if your child experiences any difficulty while taking Grenil Paed Susp, please consult your doctor.
No, you should always consult a paediatrician before giving Grenil Paed Susp to toddlers or infants. This ensures the medicine is safe for them and that you are giving the correct dose based on their weight.
If your child vomits within 15 to 20 minutes of taking the medicine, do not immediately give another dose. Talk to your doctor or pharmacist first to find out if it is safe to repeat the dose.
Yes, some children may feel quiet, sleepy, or drowsy after taking this medicine. This is a common effect and is usually nothing to worry about. Keep a close eye on your child while they rest.
It is generally best to give this medicine about 15 to 30 minutes before a meal to help prevent nausea and vomiting. However, if it upsets your child's stomach, it can be given with a little food. Talk to your doctor for advice.
No, kitchen spoons are not standard sizes and can easily lead to giving too much or too little medicine. Always use the syringe or measuring device provided in the pack. Talk to your pharmacist if you lose the measuring tool.

Disclaimer

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Country of origin

INDIA

Manufacturer/Marketer address

Dr. Rajkumar Road Rajajinagar, 1st Stage Bangalore- 560 010 India
Other Info - GRE0155
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