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Grandem 1 mg Injection 3 ml is used to treat nausea and vomiting caused by medical treatments after surgery, chemotherapy, or radiation treatment for cancer. It contains Granisetron, which works by blocking the brain's serotonin (chemical messenger) activity that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery. Common side effects of Grandem 1 mg Injection 3 ml include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

GRANISETRON-1MG

Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Grandem 1 mg Injection 3 ml

Grandem 1 mg Injection 3 ml is a prescription medication injected to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery. By blocking specific signals in the body that trigger the urge to vomit, it helps patients undergo medical treatments with greater comfort. It is typically given as a single dose shortly before your medical procedure starts.

This injection is usually given before a scheduled treatment session, so its frequency depends entirely on your medical therapy plan. Because it is given directly into a vein or muscle, there are no specific food requirements or restrictions for taking it. To help support your recovery, you can also make temporary dietary adjustments like eating dry crackers or clear broths, which help keep your stomach settled.

While Grandem 1 mg Injection 3 ml is generally well-tolerated, some people may experience mild side effects such as headaches or constipation. If you experience severe symptoms like chest pain, an irregular heartbeat, or signs of a serious allergic reaction, seek medical help immediately. Always consult your doctor if you experience any unexpected or bothersome symptoms during your treatment.

Before receiving this medicine, tell your doctor if you have certain health conditions, particularly heart rhythm issues or severe bowel blockages. Do not take this if you have had a severe allergic reaction to similar anti-nausea medications in the past. Your healthcare provider will evaluate whether this medicine is safe for your specific health history.

Some medicines can affect how this injection works, especially those that alter serotonin levels in your brain, which can lead to a rare but serious reaction. It is also important to tell your doctor if you are pregnant, breastfeeding, or managing other chronic health conditions before starting. Always discuss your complete medication list, including any over-the-counter supplements, with your healthcare team.

Uses of Grandem 1 mg Injection 3 ml

Grandem 1 mg Injection 3 ml is used in the treatment of Nausea and vomiting. The detailed uses of Grandem 1 mg Injection 3 ml are as follows:

  • Chemotherapy-induced nausea and vomiting: Grandem 1 mg Injection 3 ml helps prevent the severe urge to vomit that often occurs shortly after or several days after receiving cancer chemotherapy drugs.
  • Radiotherapy-induced nausea and vomiting: It helps protect patients undergoing whole-body or localized radiation therapy from experiencing radiation-related stomach upset.
  • Post-operative nausea and vomiting: It helps prevent or treat nausea and vomiting that can occur when waking up from anesthesia after surgical procedures.

Key Benefits

Grandem 1 mg Injection 3 ml helps prevent nausea and vomiting, making it easier for patients to stay comfortable during cancer treatment or after surgery.

  • Provides fast relief from nausea and vomiting because it is given directly into the bloodstream and starts working quickly.
  • Helps prevent dehydration by reducing repeated vomiting and fluid loss.
  • Protects the throat and stomach from irritation caused by frequent vomiting.
  • Makes cancer treatment easier to tolerate by helping control nausea during chemotherapy or radiation therapy, allowing treatment to continue as planned.
  • Supports a smoother recovery after surgery by reducing nausea and vomiting, helping protect surgical wounds and improving overall comfort.

Directions for Use

  • The timing and frequency of Grandem 1 mg Injection 3 ml will be determined by your doctor, based on your medical condition and response to treatment.
  • Grandem 1 mg Injection 3 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Grandem 1 mg Injection 3 ml Works

Grandem 1 mg Injection 3 ml helps prevent nausea and vomiting by blocking the action of serotonin, a natural chemical released during chemotherapy, radiation therapy, or surgery. Serotonin normally sends signals to the brain that trigger the feeling of nausea and the urge to vomit. By blocking these signals, Grandem 1 mg Injection 3 ml helps prevent nausea and vomiting, making you feel more comfortable during and after treatment.
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Alcohol

Caution

You are recommended to limit or avoid alcohol consumption while taking Grandem 1 mg Injection 3 ml. Alcohol intake, along with Grandem 1 mg Injection 3 ml, may lead to unwanted side effects and cause increased dizziness.

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Pregnancy

Caution

It is not known if Grandem 1 mg Injection 3 ml affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving Grandem 1 mg Injection 3 ml.

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Breast Feeding

Caution

It is not known if this medicine passes into breast milk. Please inform your doctor before taking Grandem 1 mg Injection 3 ml if you are a nursing mother.

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Driving

Caution

Grandem 1 mg Injection 3 ml may make you feel dizzy, affecting your mental ability. Do not drive or operate machinery if you experience dizziness.

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Liver

Caution

Grandem 1 mg Injection 3 ml should be used with caution if you have liver disease. Please inform your doctor if you have a history of liver impairment before starting Grandem 1 mg Injection 3 ml.

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Kidney

Caution

Grandem 1 mg Injection 3 ml should be used with caution if you have kidney problems. Please inform your doctor if you have a history of kidney impairment/kidney disease.

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Children

Caution

Safety and efficacy of Grandem 1 mg Injection 3 ml have not been established in children below 2 years of age.

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Heart

Consult your doctor

Please consult your doctor if you have any pre-existing heart disease before using Grandem 1 mg Injection 3 ml.

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Geriatrics

Consult your doctor

Limited information available about the use of Grandem 1 mg Injection 3 ml in geriatric patients. Please consult your physician.

What if I have taken an overdose of Grandem 1 mg Injection 3 ml

Because this medication is typically administered by trained medical staff, an overdose is highly unlikely. However, if you receive too much or suspect an overdose, seek immediate emergency medical attention or contact a poison control center.

Diet & Lifestyle Advise

  • Eat smaller meals: Try eating five or six small meals throughout the day instead of three large ones to avoid putting too much pressure on your stomach.
  • Choose bland foods: Stick to dry, simple foods like crackers, toast, plain rice, or oatmeal, which are easy on the digestive tract.
  • Stay hydrated slowly: Sip clear fluids like water, dilute broths, or electrolyte drinks slowly between meals rather than gulping them down during a meal.
  • Avoid strong odors: Keep your eating area well-ventilated and avoid hot, greasy, or spicy foods that have strong smells, as these can easily trigger nausea.
  • Rest upright: Avoid lying down flat for at least 30 to 60 minutes after eating or drinking to prevent acid reflux and stomach discomfort.
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How Soon It Starts Working

The time required for Grandem 1 mg Injection 3 ml to start to work: The effect of Grandem 1 mg Injection 3 ml can be observed within 1 to 4 minutes after administration. The time for which the effects of Grandem 1 mg Injection 3 ml last: Grandem 1 mg Injection 3 ml effect lasts approximately 24 hours.

What if you forget to take Grandem 1 mg Injection 3 ml

Since this medicine is usually given by a healthcare provider right before a scheduled medical procedure, it is unlikely that you will miss a dose. If you are receiving this therapy at home and miss a scheduled dose, contact your doctor or healthcare provider immediately for instructions.

Storage

• Store the medication at controlled room temperature, ideally between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Always inspect the solution inside the vial before it is used; do not use it if you notice any cloudiness, discoloration, or floating particles.
  • Ensure that all needles and syringes are disposed of immediately after a single use in a puncture-resistant sharps container.
  • If you are self-injecting at home, make sure to rotate your injection sites as directed by your nurse to prevent skin irritation.
  • Be cautious when rising from a sitting or lying position, as this medicine can occasionally cause mild dizziness.
  • Avoid driving, operating heavy machinery, or performing tasks that require full mental alertness until you know how this medicine affects you.
  • Inform any healthcare professional treating you that you are receiving Grandem 1 mg Injection 3 ml, especially before any new prescription is written.

Drug-Drug Interactions

verifiedApollotooltip
  • Serotonergic medications: Combining this medicine with certain antidepressants (like SSRIs or SNRIs) can increase the risk of a rare, life-threatening condition called serotonin syndrome.
  • Heart rhythm medicines: Medications that affect your heart's electrical rhythm may increase the risk of irregular heartbeats when used alongside Grandem 1 mg Injection 3 ml.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No clinically significant food interactions are known with Grandem 1 mg Injection 3 ml when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

FAQs

Grandem 1 mg Injection 3 ml is used to treat Nausea and vomiting.
Grandem 1 mg Injection 3 ml contains Granisetron, an anti-emetic drug. It is a serotonin blocker that blocks the activity of serotonin, a chemical messenger that induces nausea and vomiting after treatments like chemotherapy and radiation therapy. Thus, Grandem 1 mg Injection 3 ml relieves post-operative nausea and vomiting symptoms.
Grandem 1 mg Injection 3 ml should be used with caution if you have recent stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, heart rhythm disorder, a recent stomach or intestinal surgery, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases.
You are advised to complete the course prescribed by your doctor. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of nausea and vomiting.
Common side effects of Grandem 1 mg Injection 3 ml include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
It is not known if Grandem 1 mg Injection 3 ml affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving Grandem 1 mg Injection 3 ml. The doctor will prescribe Grandem 1 mg Injection 3 ml only if clearly needed.
Few studies suggest that Grandem 1 mg Injection 3 ml is more effective than ondansetron. However, the doctor will decide which medicine is suitable and better for you based on your condition.
Because it is given as an injection directly into the vein or muscle, Grandem 1 mg Injection 3 ml starts working very quickly, usually within minutes, to help prevent nausea before your medical therapy begins. Talk to your doctor for more details.
Yes, constipation is a common side effect of Grandem 1 mg Injection 3 ml because it can temporarily slow down your digestive system. Eating high-fiber foods and drinking plenty of fluids can help manage this, but you should talk to your doctor or pharmacist if the constipation becomes severe.
Yes, while it is most effective when used to prevent nausea before a procedure, it can also be given to treat active nausea and vomiting, especially after surgery. Talk to your doctor to understand your specific treatment plan.
Some patients may experience mild dizziness, drowsiness, or headaches after receiving this injection. It is recommended to avoid driving or operating machinery until you know how this medicine affects your coordination and alertness.
Grandem 1 mg Injection 3 ml is injected into a vein (intravenously) or a muscle (intramuscularly) by a trained healthcare professional in a clinic, hospital, or structured home-care environment. Talk to your doctor if you have questions about the injection process.
While there is no known major chemical interaction, consuming alcohol can worsen side effects like dizziness and dehydration, and it can further upset your stomach. Talk to your doctor or pharmacist about whether it is safe for you to drink alcohol during your recovery.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai 400 001, India.
Other Info - GRA0009
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