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Glucomust-PM Tablet is used in the treatment of Type 2 diabetes mellitus. It increases the production of insulin by acting on the pancreas, decreases liver glucose production and intestinal glucose uptake. It may cause side effects such as nausea, vomiting, diarrhoea, stomach ache, respiratory infection, weight gain, numbness, and vision problems. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

GLIBENCLAMIDE-5MG+METFORMIN-500MG+PIOGLITAZONE-15MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Glucomust-PM Tablet

Glucomust-PM Tablet is a prescription medicine in tablet form used to manage high blood sugar levels in adults with type 2 diabetes. It is designed to help control glucose levels when a single or dual-action treatment is no longer sufficient. Keeping your blood sugar in check is crucial for reducing the risk of serious health complications over time.

To achieve the best results, you must take Glucomust-PM Tablet consistently every day exactly as prescribed. It is highly recommended to take this medication with meals to lower the chances of experiencing an upset stomach. Combining your treatment with a balanced diet and routine physical activity is essential to help the medicine work effectively.

While taking Glucomust-PM Tablet , you may experience common side effects such as low blood sugar, mild weight gain, or a temporary upset stomach. If you experience any severe or persistent side effects, such as sudden shortness of breath or yellowing of your skin or eyes, contact your doctor immediately.

Before starting this medicine, talk to your doctor if you have a history of heart, kidney, or liver conditions. Do not take this if you suffer from severe kidney failure, active liver disease, severe heart failure, or diabetic ketoacidosis.

This medication can interact with other substances like alcohol, which can significantly raise your risk of severe low blood sugar or serious chemical imbalances in your blood. If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist to ensure this medicine is appropriate for your specific needs.

Uses of Glucomust-PM Tablet

Glucomust-PM Tablet is used to treat Type 2 diabetes mellitus. The detailed uses of Glucomust-PM Tablet are as follows:

  • Type 2 Diabetes Mellitus: Glucomust-PM Tablet helps lower high blood sugar levels in adults whose diabetes is not adequately controlled by other single or dual medications.
     

Key Benefits

Maintaining optimal blood sugar control with Glucomust-PM Tablet provides several key health benefits:

  • Helps Maintain Healthy Blood Sugar Levels: By improving blood sugar control throughout the day, including fasting and post-meal glucose levels, Glucomust-PM Tablet supports stable energy levels and effective diabetes management.
  • Supports Long-Term Protection Against Diabetes Complications: Maintaining healthy blood sugar levels with Glucomust-PM Tablet helps reduce the risk of diabetes-related complications, such as kidney disease, nerve damage, vision problems, and cardiovascular disease.
  • Offers Convenient Triple Combination Therapy: By combining three antidiabetic medicines into a single daily tablet, Glucomust-PM Tablet simplifies your treatment routine, supports better medication adherence, and helps maintain consistent blood sugar control.

Directions for Use

  • Glucomust-PM Tablet is taken with food to prevent hypoglycemia or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Glucomust-PM Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Glucomust-PM Tablet Works

Glucomust-PM Tablet contains three active ingredients that work in harmony through different mechanisms to manage your blood sugar. The first active component, glibenclamide, works by stimulating your pancreas to release more insulin, which is the natural hormone responsible for clearing sugar from your bloodstream. The second component, metformin, works by decreasing the amount of sugar your liver releases into your body, slowing down sugar absorption from food in your intestines, and helping your muscles use insulin better. The third component, pioglitazone, directly targets insulin resistance by making your body’s fat and muscle cells highly responsive to insulin, allowing them to absorb and clear sugar from your bloodstream more effectively.
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Alcohol

Caution

Alcohol may increase the risk of side effects and worsen the condition. Therefore, avoid alcohol consumption.

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Pregnancy

Unsafe

Glucomust-PM Tablet is a category C drug and may cause harmful effects to the unborn baby. So, it is used only when the benefits of this medicine outweigh the risks.

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Breast Feeding

Unsafe

Glucomust-PM Tablet should not be used in breastfeeding mothers as it may be secreted in the breast milk and cause unwanted effects in the nursing babies.

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Driving

Caution

Glucomust-PM Tablet may cause vision problems. So, do not drive or operate heavy machinery if you have any problems with your vision while using Glucomust-PM Tablet .

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Liver

Caution

Glucomust-PM Tablet should be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Glucomust-PM Tablet should be taken with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Glucomust-PM Tablet is not recommended for use in children below 18 years of age.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems before taking Glucomust-PM Tablet .

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Geriatrics

Consult your doctor

This medicine is not safe for use in elderly patients due to its serious side effects.

What if I have taken an overdose of Glucomust-PM Tablet

If you suspect an overdose, seek immediate medical attention or contact emergency services. An overdose of this medicine can cause severe low blood sugar, extreme confusion, rapid heart rate, or loss of consciousness.

Diet & Lifestyle Advise

  • Check your blood sugar levels regularly to monitor how your body is responding to the medication.
  • Eat a balanced diet high in dietary fibre, whole grains, and fresh vegetables while keeping your intake of sugary foods and drinks to a minimum.
  • Stay physically active with regular, moderate exercise like brisk walking to help your body use insulin more efficiently.
  • Always carry a fast-acting sugar source, such as glucose tablets, fruit juice, or hard candies, to quickly treat sudden drops in blood sugar.
  • Stay hydrated by drinking plenty of water, especially during hot weather or when exercising, to support kidney function.
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How Soon It Starts Working

The time required for Glucomust-PM Tablet to start to work: The time required for Glucomust-PM Tablet to start to work is 15 to 60 minutes after administration.

The time for which the effects of Glucomust-PM Tablet last: The duration of action for Glucomust-PM Tablet is not clinically established.

What if you forget to take Glucomust-PM Tablet

Take your missed dose with your next meal if it is close to your scheduled time. If it is almost time for your next scheduled dose, skip the missed one entirely and return to your regular schedule. Do not take a double dose to make up for a missed one, as this can cause your blood sugar to drop too low.

Storage

•Store Glucomust-PM Tablet tablets at room temperature, strictly between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from light and moisture.

Drug Warnings

  • Inspect your feet daily for any slow-healing cuts, blisters, or redness, as managing diabetes requires careful attention to foot care.
  • Get your liver and kidney function checked regularly using routine blood tests as advised by your doctor.
  • Do not skip meals while taking this medication, as a lack of food can trigger a severe drop in your blood sugar levels.
  • Avoid alcohol completely, as it significantly increases your risk of severe low blood sugar and a serious acid buildup in your blood.
  • Tell any dentist, surgeon, or medical specialist that you are taking Glucomust-PM Tablet before you have any procedure or scan involving contrast dyes.
  • Tell your doctor immediately if you notice blood in your urine, pain while passing urine, or a new or persistent urge to urinate.
  • Pioglitazone has been associated with an increased risk of bladder cancer in some studies, and these symptoms should be evaluated promptly.
  • Pioglitazone may increase the risk of bone fractures, particularly in older women. Talk to your doctor about maintaining bone health through adequate calcium, vitamin D, exercise, and other preventive measures where appropriate. 

Drug-Drug Interactions

verifiedApollotooltip
  • Beta-blockers: May mask the physical warning signs of low blood sugar, such as a fast heartbeat or shakiness.
  • Water pills (diuretics) and steroids: Can raise your blood sugar levels, making Glucomust-PM Tablet less effective.
  • Pain relievers (NSAIDs): Can increase the risk of low blood sugar and strain your kidneys when used together with this medicine.
  • Contrast dyes used in medical scans: May increase the risk of a rare, serious acid buildup in the blood; your doctor may advise you to stop taking Glucomust-PM Tablet temporarily.
Metformin + Pioglitazone + GlibenclamideIodixanol
Critical
Metformin + Pioglitazone + GlibenclamideIodamide
Critical

Drug-Drug Interactions

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Metformin + Pioglitazone + GlibenclamideIodixanol
Critical
How does the drug interact with Glucomust-PM Tablet:
Co-administration of Iodixanol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iodixanol is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Metformin + Pioglitazone + GlibenclamideIodamide
Critical
How does the drug interact with Glucomust-PM Tablet:
Co-administration of Metformin and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Metformin with Iodamide is generally avoided as it can result in an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Metformin + Pioglitazone + GlibenclamideGatifloxacin
Critical
How does the drug interact with Glucomust-PM Tablet:
Co-administration of Metformin with Gatifloxacin can cause both hypoglycemia (low blood glucose) and, less frequently, hyperglycemia (high blood glucose).

How to manage the interaction:
There is a possibility of interaction between Metformin and Gatifloxacin but they can be taken together if a doctor has prescribed them. Do not discontinue without consulting a doctor.
Metformin + Pioglitazone + GlibenclamideIomeprol
Critical
How does the drug interact with Glucomust-PM Tablet:
Co-administration of Iomeprol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iomeprol is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Metformin + Pioglitazone + GlibenclamideIopamidol
Critical
How does the drug interact with Glucomust-PM Tablet:
Co-administration of Iopamidol with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Metformin with Iopamidol is not recommended, consult a doctor before taking it. Do not discontinue any medications without consulting a doctor.
Metformin + Pioglitazone + GlibenclamideIopromide
Critical
How does the drug interact with Glucomust-PM Tablet:
Co-administration of Iopromide with Metformin can increase the risk of lactic acidosis (a medical condition characterized by a build-up of lactate in the body).

How to manage the interaction:
Taking Iopromide with Metformin is not recommended, consult a doctor before taking it. Do not discontinue any medications without consulting a doctor.
Metformin + Pioglitazone + GlibenclamideMetrizamide
Critical
How does the drug interact with Glucomust-PM Tablet:
Co-administration of Metformin and Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Metformin with Metrizamide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Metformin + Pioglitazone + GlibenclamideMoxifloxacin
Severe
How does the drug interact with Glucomust-PM Tablet:
Co-administration of Moxifloxacin may affect blood glucose levels. Both high blood glucose and low blood glucose.

How to manage the interaction:
Although there is a possible interaction, glibenclamide can be taken with moxifloxacin if prescribed by the doctor. Consult the prescriber if you experience nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, increased urination, increased thirst, and increased hunger. Do not discontinue the medications without consulting a doctor.
Metformin + Pioglitazone + GlibenclamideTopiramate
Severe
How does the drug interact with Glucomust-PM Tablet:
The combined use of Metformin and Topiramate may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Coadministration Metformin and Topiramate can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as weakness, muscle pain, respiratory distress, fatigue, loss of appetite, slow or irregular heartbeat, breathing difficulty, or chills consult the doctor immediately. Do not stop using any medication without a doctor's advice.
Metformin + Pioglitazone + GlibenclamideMipomersen
Severe
How does the drug interact with Glucomust-PM Tablet:
Co-administration of Mipomersen and Pioglitazone may increase the risk of liver damage.

How to manage the interaction:
Although taking Pioglitazone and Mipomersen together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Can cause severe, unpredictable drops in blood sugar and increases the risk of lactic acidosis.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS AND ANTIHYPERGLYCEMICS]

FAQs

Glucomust-PM Tablet is used in the treatment of type 2 diabetes mellitus.
Glucomust-PM Tablet is a combination of three antidiabetic medicines, Glibenclamide, Metformin, and Pioglitazone. It works by increasing insulin production, helping restore your body's appropriate response to insulin, and thereby lowering your elevated blood sugar levels.
Glucomust-PM Tablet is used to treat type 2 diabetes. It is not recommended for the treatment of type 1 diabetes.
Glucomust-PM Tablet may cause hypoglycemia (low blood sugar levels). Hypoglycemia can occur if you miss or delay your food, drink alcohol, engage in intense exercise, or take other antidiabetic medicines along with this medicine. So, take your medicine as advised by your doctor to avoid any unwanted effects of this medicine.
You may experience symptoms such as increased thirst and hunger, frequent urination, weight loss, delayed wound healing, and frequent infections if you have diabetes. Consult a doctor to confirm the diagnosis.
Stopping Glucomust-PM Tablet may cause a rise in blood sugar levels. Therefore, continue taking Glucomust-PM Tablet as directed even if your symptoms improve.
Regularly monitor your blood sugar levels and keep your doctor informed about any kidney or heart issues. If you have allergies, are pregnant, or are breastfeeding, consult your doctor before using this medication. Maintain a healthy lifestyle, including a balanced diet and regular exercise, and stay hydrated by drinking plenty of water. Also, be sure to disclose all medications you're taking to your doctor to avoid potential interactions. By following these guidelines, you'll be able to use this medication safely and effectively.
Some individuals may feel tired and drowsy after taking Glucomust-PM Tablet . Drive or operate machinery only if you are alert. If you're experiencing any of these symptoms persistantly, it's crucial to consult your doctor.
No, Glucomust-PM Tablet does not contain steroids. Glucomust-PM Tablet is a medication specifically designed to manage type 2 diabetes. It's a combination therapy that helps regulate blood sugar levels.
Glucomust-PM Tablet may take around 2-3 months to reach its full effect, but you may start noticing improvements in your blood sugar control within the first few weeks.
It is generally safe to take Glucomust-PM Tablet and Fexofenadine together if it is prescribed by your doctor. Fexofenadine is an antihistamine used to treat allergies, and it doesn't typically interact with Glucomust-PM Tablet . However, it's always best to consult your doctor or pharmacist before combining any medications.
The common side effects of Glucomust-PM Tablet include nausea, vomiting, and stomach issues. Consult the doctor if the side effects persist or worsen.
It is highly recommended to avoid alcohol while taking Glucomust-PM Tablet . Alcohol can increase your risk of experiencing dangerously low blood sugar levels and can also increase the risk of a rare but life-threatening condition called lactic acidosis. Talk to your doctor or pharmacist if you have questions about alcohol use.
If you feel shaky, sweaty, dizzy, or hungry, your blood sugar may have dropped too low. Immediately consume a fast-acting sugar source, such as half a cup of fruit juice, three to four glucose tablets, or hard candies. If symptoms persist or worsen, contact your doctor right away.
Yes, some people may experience weight gain while taking Glucomust-PM Tablet . This can be due to improved blood sugar control or fluid retention. Eating a balanced diet and exercising regularly can help manage your weight. Talk to your doctor if you notice sudden or significant weight gain, especially in your face, ankles, or feet.
Do not take Glucomust-PM Tablet if you are pregnant, planning to become pregnant, or breastfeeding unless specifically directed by your doctor. Other treatments are typically preferred to manage blood sugar during pregnancy and breastfeeding. Talk to your doctor or pharmacist to discuss safer options.
Lactic acidosis is a rare but very serious medical emergency caused by a buildup of acid in your blood. Symptoms include unusual muscle pain, trouble breathing, severe stomach discomfort, or feeling unusually cold and weak. If you experience these symptoms, stop taking Glucomust-PM Tablet and seek immediate medical help.
Unless your doctor or the product information specifically states otherwise, swallow Glucomust-PM Tablet tablets whole with a glass of water. Follow the administration instructions provided with your specific product. If you have difficulty swallowing tablets, speak with your doctor or pharmacist before altering the tablet.

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Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - GLU0155
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