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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Gennomax 250mg Injection is used to prevent the formation of blood clots. It works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack) or stroke, especially in people who have had heart surgery, known as angioplasty.

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Composition :

BIVALIRUDIN-250MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Gennomax 250mg Injection

Gennomax 250mg Injection belongs to the group of medicines called blood thinners used to prevent the formation of blood clots. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful for stopping bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels. Gennomax 250mg Injection is used in combination with aspirin during Percutaneous transluminal coronary angioplasty (PTCA) and Percutaneous coronary intervention (PCI) (angioplasty procedures) in unstable angina patients to reduce the chance of blood clot formation.

Gennomax 250mg Injection contains Bivalirudin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. This results in lower cardiovascular events like myocardial infarction (heart attack) or other severe chest pain-related problems.

Gennomax 250mg Injection will be administered by your doctor. So, do not self-administer. The dose of the medicine will be decided by your doctor based on your health condition. Gennomax 250mg Injection may cause certain side effects such as nose bleeds, skin rash, bleeding in the bowels, blood in urine, low haemoglobin, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme levels. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Gennomax 250mg Injection should not be used if you are allergic to it or if you ever had a brain stroke, bleeding in the brain or transient ischemic attack (stroke). Talk to your doctor before receiving Gennomax 250mg Injection if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems, have/had a heart problem, kidney disease or using any blood thinner medicine. Pregnant or breastfeeding mothers should inform the doctor before receiving this medicine. Gennomax 250mg Injection is not recommended for children as efficacy and safety have not been established.

Uses of Gennomax 250mg Injection

Gennomax 250mg Injection is used to prevent blood clots. The detailed uses of Gennomax 250mg Injection are as follows:<br/>• Prevents the formation of blood clots: Gennomax 250mg Injection inhibits fibrin production, stopping platelets from clumping together to form clots.<br/>• Reduces the risk of heart attack and stroke: Gennomax 250mg Injection lowers the chance of serious cardiovascular events, especially in patients undergoing procedures like angioplasty.<br/>• Provides protection after heart surgeries: Gennomax 250mg Injection helps maintain healthy blood flow and prevents clot-related complications following cardiac interventions.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Gennomax 250mg Injection will be administered by the doctor or healthcare professional in a medical setting.• Do not self-administer.

Medicinal Benefits

Gennomax 250mg Injection belongs to the group of medicines called antithrombolytic agents (direct thrombin inhibitors) used to prevent the formation of blood clots. Gennomax 250mg Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack) or stroke, especially in people who have had heart surgery, known as angioplasty.

How Gennomax 250mg Injection Works

Gennomax 250mg Injection contains Bivalirudin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. This results in lower cardiovascular events like myocardial infarction (heart attack) or other severe chest pain-related problems.

Storage

• Store in a cool and dry place away from sunlight.• Keep Gennomax 250mg Injection out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Gennomax 250mg Injection

What if I have taken an overdose of Gennomax 250mg Injection

Since Gennomax 250mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Do not receive Gennomax 250mg Injection if you are allergic to it or if you have a medical condition that causes bleeding from the stomach or intestine, had a transient ischemic attack (stroke) or if you are suffering from severe liver disease. Let your doctor know if you have bleeding problems, had/have a recent serious injury or surgery, kidney/liver disease, or are taking any blood thinner medicine before receiving this medicine. Consult your doctor immediately if you develop a medical condition called thrombotic thrombocytopenic purpura (blood disorder) while on treatment with Gennomax 250mg Injection. Pregnant or breastfeeding mothers should inform their doctor before receiving this medicine. Gennomax 250mg Injection is not recommended for children as efficacy and safety have not been established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Gennomax 250mg Injection:
When Etodolac is taken with Gennomax 250mg Injection, the risk or severity of bleeding and haemorrhage increases.

How to manage the interaction:
Taking Gennomax 250mg Injection with Estradiol can cause an interaction, consult a doctor before taking it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Gennomax 250mg Injection:
Co-administration of Mifepristone with Gennomax 250mg Injection can increase the risk of negative side effects.

How to manage the interaction:
Taking Gennomax 250mg Injection with Mifepristone together is not generally recommended as it may lead to an interaction, but it can be taken if prescribed by a doctor. However, if you experience persistent, excessive bleeding, consult the doctor. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Gennomax 250mg Injection:
Taking Dabigatran etexilate with Gennomax 250mg Injection can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Gennomax 250mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gennomax 250mg Injection:
Using Deferasirox together with Gennomax 250mg Injection may increase the risk of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Co-administration of Gennomax 250mg Injection with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gennomax 250mg Injection:
Coadministration of Gennomax 250mg Injection and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Gennomax 250mg Injection and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Gennomax 250mg Injection:
Coadministration of Gennomax 250mg Injection with Enoxaparin can increase the risk or severity of bleeding.

How to manage the interaction:
Co-administration of Gennomax 250mg Injection with Enoxaparin can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like bleeding, bruising, dizziness, black or red stools, severe headache, weakness, or vomiting call a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Gennomax 250mg Injection:
Taking Gennomax 250mg Injection with Heparin may increase the risk of bleeding.

How to manage the interaction:
Although taking Gennomax 250mg Injection and Heparin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gennomax 250mg Injection:
Co-administration of Prasugrel with Gennomax 250mg Injection can increase the risk of bleeding.

How to manage the interaction:
Although taking Prasugrel and Gennomax 250mg Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gennomax 250mg Injection:
Co-administration of Ibrutinib with Gennomax 250mg Injection can increase the risk of bleeding.

How to manage the interaction:
Taking Ibrutinib with Gennomax 250mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gennomax 250mg Injection:
Taking cefdinir with Gennomax 250mg Injection may increase the effects of Gennomax 250mg Injection.

How to manage the interaction:
Although taking Cefdinir and Argatroban together can evidently cause an interaction, but it can be taken if prescribed by a doctor. In case you experience any side effects like chest tightness, shortness of breath, swelling of legs, or palpitations, consult a doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS
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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption while receiving Gennomax 250mg Injection to prevent unpleasant side effects.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Gennomax 250mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited data are available on the effect of Gennomax 250mg Injection on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Gennomax 250mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Gennomax 250mg Injection does not affect your ability to drive.

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Liver

Caution

Gennomax 250mg Injection should be used with caution in patients with liver impairment. Please inform your doctor if you have liver disease or any concerns regarding this.

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Kidney

Caution

Gennomax 250mg Injection should be used with caution in patients with kidney impairment. Please inform your doctor if you have kidney disease or any concerns regarding this.

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Children

Unsafe

Gennomax 250mg Injection is not recommended for use in children, as efficacy and safety have not been established.

Have a query?

FAQs

Gennomax 250mg Injection is used to prevent blood clots.

Gennomax 250mg Injection works by inhibiting the clumping of platelets, thereby reducing the chance of blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack).

No, you are not recommended to take ibuprofen with Gennomax 250mg Injection as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Gennomax 250mg Injection.

Gennomax 250mg Injection may cause anaemia (low haemoglobin and low red blood cell count). So it would be best if you include iron-rich food in your diet to prevent anaemia.

Gennomax 250mg Injection does not affect the functioning of the liver. However, long-term use of Gennomax 250mg Injection may slightly increase the risk of mild liver damage, particularly in those with increased liver enzyme levels. Therefore, if you have any liver problem, please inform your doctor before starting Gennomax 250mg Injection.

It is best to avoid drinking alcohol while taking Gennomax 250mg Injection. Intake of alcohol might increase the risk of stomach or intestinal bleeding.

Store Gennomax 250mg Injection at controlled room temperature (15-25°C) in a cool and dry place. Do not freeze. Keep out of reach of children.

You might not feel any difference after taking Gennomax 250mg Injection, but you should continue taking it as prescribed by your doctor. Even though you don't notice any difference, you will still receive all benefits of Gennomax 250mg Injection.

Gennomax 250mg Injection should not be taken by individuals with allergies, bleeding issues, strokes, liver disease, or taking any blood thinners. It is important to inform your doctor if you develop thrombotic thrombocytopenic purpura while on treatment with Gennomax 250mg Injection. Pregnant or breastfeeding mothers should inform your doctor before receiving Gennomax 250mg Injection. Gennomax 250mg Injection is not recommended for children as efficacy and safety have not been established.

No, Gennomax 250mg Injection does not usually cause hair loss. However if you notice hair loss while on treatment with Gennomax 250mg Injection, please consult your doctor.

The common side effects of Gennomax 250mg Injection are nose bleeds, skin rash, bruising, bleeding in the bowels, blood in urine, low haemoglobin, and thrombocytopenia (low platelets). If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India
Other Info - GE49292

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