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  3. Fosa 150Mg Inj

Fosa 150Mg Inj, Pack of 1 INJECTION
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Fosa 150Mg Inj is used to manage Chemotherapy-induced nausea and vomiting. It contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps to prevent nausea and vomiting caused by anti-cancer medicines in patients six months of age and above.

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Composition :

APREPITANT-150MG

Manufacturer/Marketer :

Mylan Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Fosa 150Mg Inj

Fosa 150Mg Inj belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in patients six months of age and above. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Fosa 150Mg Inj contains Aprepitant, a neurokinin 1 (NK1) receptor antagonist which works by blocking neurokinin-1 receptors (causes the feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting. 

Fosa 150Mg Inj will be administered by a healthcare professional; do not self-administer. In some cases, Fosa 150Mg Inj may cause common side effects such as weakness, tiredness, diarrhoea, urinary tract infection, pain in arms and legs, or indigestion. Most of these side effects do not require medical attention and gradually resolve over time. However, consult your doctor immediately if the side effects persist or worsen. 

If you are allergic to Fosa 150Mg Inj or any other medicines, please tell your doctor. Fosa 150Mg Inj is not recommended for children below six months of age. If you are pregnant or breastfeeding, please inform your doctor before taking Fosa 150Mg Inj. Drive only if you are alert after receiving Fosa 150Mg Inj. If you are taking other prescription or non-prescription medicines, inform your doctor before taking Fosa 150Mg Inj. 

Uses of Fosa 150Mg Inj

Fosa 150Mg Inj is used in the prevention of nausea and vomiting caused by cancer chemotherapy. The detailed uses of Fosa 150Mg Inj are as follows:<br/>• Chemotherapy-induced nausea and vomiting (CINV): Fosa 150Mg Inj helps prevent both acute and delayed nausea and vomiting associated with cancer chemotherapy.<br/>• Supportive care in cancer treatment: Fosa 150Mg Inj is commonly used as part of antiemetic regimens to improve patient comfort and treatment adherence during chemotherapy.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Fosa 150Mg Inj will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Fosa 150Mg Inj contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines in patients six months of age and above.

How Fosa 150Mg Inj Works

Fosa 150Mg Inj contains Aprepitant, a neurokinin 1 (NK1) receptor antagonist which works by blocking neurokinin-1 receptors (causes the feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting.

Storage

• Store in a cool and dry place away from sunlight.• Keep Fosa 150Mg Inj out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Fosa 150Mg Inj
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Fosa 150Mg Inj

Since Fosa 150Mg Inj is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

If you are allergic to Fosa 150Mg Inj or any other medicines, please tell your doctor. Fosa 150Mg Inj is not recommended for children below 6 months of age. If you are pregnant or breastfeeding, please inform your doctor before taking Fosa 150Mg Inj. Drive only if you are alert after receiving Fosa 150Mg Inj. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking Fosa 150Mg Inj. If you are using warfarin (blood thinner), your doctor may recommend blood tests after you receive Fosa 150Mg Inj to check your blood clotting.

Drug-Drug Interactions

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FosaprepitantLomitapide
Critical
FosaprepitantPimozide
Critical

Drug-Drug Interactions

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FosaprepitantLomitapide
Critical
How does the drug interact with Fosa 150Mg Inj:
When Fosa 150Mg Inj is taken with Lomitapide, it can increase the levels of Lomitapide. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj with Lomitapide together is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - diarrhea, nausea, vomiting, pain, discomfort, indigestion, constipation, liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, dark colored urine, bleeding or vomiting - make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
FosaprepitantPimozide
Critical
How does the drug interact with Fosa 150Mg Inj:
When Pimozide is taken with Fosa 150Mg Inj, it can increase the Pimozide levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj with Pimozide is not recommended, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, prolonged diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantFlibanserin
Critical
How does the drug interact with Fosa 150Mg Inj:
Coadministration of Fosa 150Mg Inj with Flibanserin can increase the levels of Flibanserin in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj with Flibanserin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FosaprepitantTerfenadine
Critical
How does the drug interact with Fosa 150Mg Inj:
When Fosa 150Mg Inj is taken with Terfenadine, it can lower the rate at which Fosa 150Mg Inj is broken down and increases its levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj and Terfenadine together is generally avoided as it can show an interaction, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like Chest discomfort, Shortness of breath, Weakness, or palpitations, it's important to call your doctor right away - they can be serious heart problems. Do not discontinue any medications without consulting a doctor.
FosaprepitantCisapride
Critical
How does the drug interact with Fosa 150Mg Inj:
Coadministration of Fosa 150Mg Inj with Cisapride can increase the levels of Cisapride in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj with Cisapride together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantAstemizole
Critical
How does the drug interact with Fosa 150Mg Inj:
Coadministration of Fosa 150Mg Inj with Astemizole can increase the levels of Astemizole in the body. This increases the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Fosa 150Mg Inj with Astemizole together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantEliglustat
Critical
How does the drug interact with Fosa 150Mg Inj:
When Fosa 150Mg Inj is taken with Eliglustat, can increase Eliglustat levels in the body. This can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Fosa 150Mg Inj and Eliglustat, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantBromocriptine
Severe
How does the drug interact with Fosa 150Mg Inj:
Fosa 150Mg Inj may considerably raise the blood levels of bromocriptine. This may enhance the risk of side effects.

How to manage the interaction:
Although there is an interaction between bromocriptine and Fosa 150Mg Inj, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, headache, dizziness, drowsiness, or lightheadedness. Do not stop using any medications without consulting a doctor.
FosaprepitantCobimetinib
Severe
How does the drug interact with Fosa 150Mg Inj:
Coadministration of Fosa 150Mg Inj with Cobimetinib can increase the levels of Cobimetinib in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj with Cobimetinib together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, diarrhea, mouth sores, bleeding, heart problems, rash, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantLemborexant
Severe
How does the drug interact with Fosa 150Mg Inj:
Coadministration of Fosa 150Mg Inj with Lemborexant can increase the blood levels of lemborexant. This may increase the risk of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj with Lemborexant together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience abnormal sleep behaviors, worsening of depression, changes in heartbeat, or headache, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, skinless poultry, lean meats, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting. 
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated. 
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Fosa 150Mg Inj Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

The interaction of alcohol with Fosa 150Mg Inj is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before taking Fosa 150Mg Inj. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Consult your doctor

It is unknown whether Aprepitant is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before receiving Fosa 150Mg Inj.

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Driving

Caution

Drive only if you are alert after receiving Fosa 150Mg Inj.

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Liver

Caution

If you have liver disease, inform your doctor before taking Fosa 150Mg Inj.

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Kidney

Consult your doctor

If you have any kidney problems, inform your doctor before taking Fosa 150Mg Inj.

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Children

Caution

Fosa 150Mg Inj is not recommended for children below six months of age as the safety and effectiveness are unknown.

Have a query?

FAQs

Fosa 150Mg Inj is used to treat Chemotherapy-induced nausea and vomiting.

Fosa 150Mg Inj works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines.

Fosa 150Mg Inj may cause weakness as a common side effect. However, if the weakness persists or worsens, consult your doctor.

You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain Intrauterine devices (IUDs) as they may not work properly when taken together with Fosa 150Mg Inj. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Fosa 150Mg Inj and for up to 1 month after using Fosa 150Mg Inj.

Yes, Fosa 150Mg Inj is an anti-emetic drug, that helps to treat nausea and vomiting which may occur after receiving cancer chemotherapy treatment.

Fosa 150Mg Inj rarely causes serious side effects, which may include allergic reactions, breathing difficulties, and severe stomach pain in some individuals.

Fosa 150Mg Inj does not reduce the effectiveness of all types of contraceptives. It may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, and injections). It is advised to use another method of contraception (like condoms, diaphragm) to prevent pregnancy while taking Fosa 150Mg Inj. Talk to your doctor about other ways to prevent pregnancy while taking this medication.

Fosa 150Mg Inj is given before chemotherapy treatment to prevent nausea and vomiting caused by chemotherapy treatment.

Yes, there are some dietary restrictions while taking Fosa 150Mg Inj. It is recommended to avoid alcohol, heavy meals, and fatty foods. Instead, you should follow a healthy, low-fat diet that includes fruits, vegetables, lean meats, and whole grains.

During chemotherapy, avoid raw/undercooked foods, processed (packaged) foods, fried foods, unpasteurized dairy, sugar, probiotics, alcohol, smoking, excessive UV exposure, and new medications/supplements.

Fosa 150Mg Inj may cause common side effects in some individuals such as weakness, tiredness, diarrhoea, urinary tract infection, pain in arms and legs, or indigestion. Most of these side effects do not require medical attention and gradually resolve over time. However, consult your doctor immediately if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7th to 12th floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103
Other Info - FOS0045

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:05 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.merck.com/product/usa/pi_circulars/e/emend_iv/emend_iv_ppi.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/209296s003lbl.pdf
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