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compositionComposition:DEFERASIROX-180MG
prescription
Prescription Medicine
info
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Ferasiro 180 Tablet 10's is used to treat iron overload due to transfusional hemosiderosis (the accumulation of iron in the body due to frequent blood transfusions) or non-transfusion-dependent thalassemia (patients who do not require lifelong regular transfusions for survival). It works by binding to the extra iron and facilitates its removal from the body through faeces. In some cases, this medicine may cause side effects like diarrhoea, vomiting, nausea, abdominal pain, and skin rashes.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DEFERASIROX-180MG

Manufacturer/Marketer :

Msn Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Ferasiro 180 Tablet 10's

Ferasiro 180 Tablet 10's is an oral prescription medicine used to treat chronic iron overload in the body. This condition often happens when you receive frequent blood transfusions or have certain blood disorders. By removing excess iron, this medicine helps prevent damage to your vital organs over time.

To get the best results, you must take Ferasiro 180 Tablet 10's once daily at the same time every day, on an empty stomach or with a light meal. Staying consistent with this daily routine is key to keeping your iron levels in a safe range.

While taking this medicine, you might experience mild side effects like nausea, diarrhoea, or skin rashes. However, it is crucial to contact your doctor immediately if you experience severe abdominal pain, yellowing of your eyes or skin, or a sudden decrease in urination.

Do not take this if you have severe kidney disease, advanced liver disease, or high-risk myelodysplastic syndrome. Before starting Ferasiro 180 Tablet 10's, tell your doctor if you have a history of ulcers, bleeding in your stomach, or blood disorders.

This medicine can interact with certain pain relievers, blood thinners, and antacids, which can increase your risk of stomach bleeding or lower the medicine's effectiveness. If you are pregnant, breastfeeding, or planning a pregnancy, talk to your doctor or pharmacist before starting this treatment.

Uses of Ferasiro 180 Tablet 10's

Ferasiro 180 Tablet 10's is used for treating chronic iron overload that occurs due to blood transfusions. The detailed uses of Ferasiro 180 Tablet 10's are as follows:

  • Chronic iron overload from blood transfusions: When you receive multiple blood transfusions, your body accumulates excess iron that it cannot naturally remove. Ferasiro 180 Tablet 10's binds to this extra iron so your body can pass it out through waste.
  • Chronic iron overload in non-transfusion-dependent thalassemia: Some blood disorders cause your body to absorb too much iron from food, even without blood transfusions. Ferasiro 180 Tablet 10's helps lower these elevated iron levels to safe ranges.

Key Benefits

Ferasiro 180 Tablet 10's helps protect your vital organs, such as your liver, heart, and pancreas, from the toxic effects of iron buildup.

Benefits may include:

  • By removing excess iron from your body, Ferasiro 180 Tablet 10's helps protect important organs such as the liver, heart, and pancreas from iron-related damage, supporting long-term health.
  • Regular treatment helps keep iron levels under control, reducing the risk of complications associated with chronic iron overload.
  • Unlike older iron-removal therapies that required lengthy daily infusions under the skin, Ferasiro 180 Tablet 10's is available as an oral tablet, making treatment more convenient and easier to fit into your daily routine.
  • Its easy-to-take oral formulation allows you to manage your condition at home with minimal disruption to your everyday activities.
Side effects of Ferasiro 180 Tablet
  • Your doctor may recommend medications to dissolve the small gallstones (like ursodiol) or use shock waves to break up the stones.
  • Try to eat regular meals because skipping meals can increase the risk of gallstones by making your gallbladder work less efficiently.
  • Eat breakfast soon after you wake up, as cholesterol in bile is highest in the morning.
  • If you are overweight, losing weight gradually can help lower the chance of developing gallstones.
  • Include plenty of fresh vegetables and fruits in your diet.
  • Base your meals around starchy foods like bread, pasta, rice, and potatoes, especially whole grain or high-fibre varieties.

Directions for Use

  • Ferasiro 180 Tablet 10's should be taken on an empty stomach, at least 30 minutes before a meal.
  • Follow your doctor's instructions on the dosage and timing of this medication. However, it is suggested to take Ferasiro 180 Tablet 10's at the same time each day to maintain a consistent level of medicine in your body.
  • Swallow the whole Ferasiro 180 Tablet 10's with a glass of water.
  • Do not break, chew, or crush it.

How Ferasiro 180 Tablet 10's Works

Ferasiro 180 Tablet 10's works as an iron chelator, which binds tightly to the free, excess iron molecules and forms a stable compound that your body can easily process. This bound iron is then naturally filtered out and excreted from your body, primarily through your bowel movements (faeces). This process gradually lowers your total body iron stores to a safer level.
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Alcohol

Caution

Consuming alcohol along with Ferasiro 180 Tablet 10's is not advisable, as it may cause unpleasant side effects, or you also may become more sensitive to the effects of alcohol.

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Pregnancy

Consult your doctor

Ferasiro 180 Tablet 10's is not usually recommended if you are pregnant. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks. Please consult the doctor.

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Breast Feeding

Consult your doctor

Ferasiro 180 Tablet 10's is not usually recommended if you are a lactating woman. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks.

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Driving

Caution

It is not known whether Ferasiro 180 Tablet 10's alters the ability to drive, so do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react.

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Liver

Caution

Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Ferasiro 180 Tablet 10's should be used under the supervision of healthcare provider

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Heart

Caution

Ferasiro 180 Tablet 10's should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Ferasiro 180 Tablet 10's.

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Geriatrics

Caution

Ferasiro 180 Tablet 10's should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform your doctor before using it.

What if I have taken an overdose of Ferasiro 180 Tablet 10's

If you accidentally take too much Ferasiro 180 Tablet 10's, seek emergency medical attention or contact a poison control centre immediately. Overdose can lead to severe stomach upset, liver or kidney issues, and other serious health complications.

Diet & Lifestyle Advise

  • Avoid vitamin C supplements: High doses of vitamin C can increase how much iron your body absorbs and may interact with how this medicine works. Only take vitamin C if specifically directed by your doctor.
  • Stay well hydrated: Drink plenty of water throughout the day. This helps your kidneys flush out waste and reduces the strain on your kidneys while taking this medicine.
  • Avoid iron-fortified foods: Limit your intake of foods that are heavily fortified with iron, and avoid using cast-iron cookware, as this can add extra iron to your food.
  • Limit alcohol consumption: Alcohol can put extra stress on your liver. Since both iron overload and this medicine can affect your liver, it is best to limit or avoid alcohol.
health query

Have a query?

How Soon It Starts Working

  • The time required for Ferasiro 180 Tablet 10's to start to work: The exact onset time of Ferasiro 180 Tablet 10's has not been clinically established.
  • The time for which the effects of Ferasiro 180 Tablet 10's last: The duration of Ferasiro 180 Tablet 10's’s effect is clinically not established.

What if you forget to take Ferasiro 180 Tablet 10's

If you miss a dose, take it as soon as you remember on that day. However, if it is almost time for your next dose, skip the missed one and return to your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Ferasiro 180 Tablet 10's at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Get regular blood tests: You will need frequent blood and urine tests to monitor your kidney and liver function, as well as your iron levels. Do not skip these appointments.
  • Schedule eye and ear exams: This medicine can occasionally affect your vision and hearing. Your doctor may recommend regular checkups to monitor for any changes.
  • Do not take with aluminium-containing antacids: These products can bind to the medicine in your stomach and stop it from working correctly.
  • Watch for skin changes: If you develop any skin rash that spreads, blisters, or peels, stop taking the medicine and contact your doctor immediately.
  • Report unusual bruising or bleeding: If you notice unusual bruising, nosebleeds, or blood in your urine, notify your healthcare provider right away.

Drug-Drug Interactions

verifiedApollotooltip
  • Aluminium-containing antacids: May bind to Ferasiro 180 Tablet 10's in your digestive tract, reducing its absorption and making it less effective.
  • Blood thinners (e.g., warfarin): Taking these medicines with Ferasiro 180 Tablet 10's can increase your risk of stomach ulcers and internal bleeding.
  • NSAID pain relievers (e.g., ibuprofen): May increase the risk of stomach irritation, ulcers, and internal bleeding.
  • Certain cholesterol-lowering drugs (e.g., cholestyramine): May lower the levels of Ferasiro 180 Tablet 10's in your body, reducing its effectiveness.
  • Antihyperglycemic agents (e.g., repaglinide): Ferasiro 180 Tablet 10's can increase the levels of repaglinide in your body, raising the risk of low blood sugar (hypoglycaemia).
DeferasiroxCapreomycin
Severe
DeferasiroxGentamicin
Severe

Drug-Drug Interactions

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DeferasiroxCapreomycin
Severe
How does the drug interact with Ferasiro 180 Tablet:
Ferasiro 180 Tablet may cause kidney problems and combining it with capreomycin may increase that risk.

How to manage the interaction:
Although taking Capreomycin and Ferasiro 180 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhoea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
DeferasiroxGentamicin
Severe
How does the drug interact with Ferasiro 180 Tablet:
Taking Ferasiro 180 Tablet may cause kidney problems and combining it with gentamicin may increase that risk.

How to manage the interaction:
Although there is a possible interaction, gentamicin can be taken with Ferasiro 180 Tablet if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Dehydration can also harm the kidney, therefore drink plenty of fluids if you develop diarrhoea or vomiting during treatment with these medications.
DeferasiroxDabigatran etexilate
Severe
How does the drug interact with Ferasiro 180 Tablet:
Combining Dabigatran etexilate with Ferasiro 180 Tablet can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Dabigatran etexilate with Ferasiro 180 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxFludrocortisone
Severe
How does the drug interact with Ferasiro 180 Tablet:
Using Ferasiro 180 Tablet together with fludrocortisone may increase the risk of stomach ulcers and bleeding.

How to manage the interaction:
Co-administration of Fludrocortisone with Ferasiro 180 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts. If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxSirolimus
Severe
How does the drug interact with Ferasiro 180 Tablet:
Coadministration of Ferasiro 180 Tablet with Sirolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Sirolimus and Ferasiro 180 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhoea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
DeferasiroxDasatinib
Severe
How does the drug interact with Ferasiro 180 Tablet:
Coadministration of Ferasiro 180 Tablet together with Dasatinib may increase the risk of bleeding.

How to manage the interaction:
Although taking Dasatinib and Ferasiro 180 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, like stomach pain, feeling dizzy, it's important to call a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxKetoconazole
Severe
How does the drug interact with Ferasiro 180 Tablet:
Coadministration of Ketoconazole and Ferasiro 180 Tablet may increase the risk of liver injury.

How to manage the interaction:
Although taking Ketoconazole and Ferasiro 180 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medication without consulting a doctor.
DeferasiroxStreptomycin
Severe
How does the drug interact with Ferasiro 180 Tablet:
Coadministration of Ferasiro 180 Tablet and Streptomycin can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Ferasiro 180 Tablet and Streptomycin together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience a fast heartbeat, anxiety, constipation, cough, dark urine, diarrhea, dizziness, lightheadedness, fainting, fever, hives or welts, itching skin or rash consult a doctor. Do not discontinue any medications without consulting a doctor.
DeferasiroxEtidronic acid
Severe
How does the drug interact with Ferasiro 180 Tablet:
Combining Etidronic acid (oral form) with Ferasiro 180 Tablet can increase the risk of bleeding and ulcers in the stomach and intestines.

How to manage the interaction:
Co-administration of Etidronic acid with Ferasiro 180 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxDanaparoid
Severe
How does the drug interact with Ferasiro 180 Tablet:
Combining Danaparoid with Ferasiro 180 Tablet can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Danaparoid with Ferasiro 180 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Ferasiro 180 Tablet 10's when used as directed.

DEFERASIROX-180MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEFERASIROX-180MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
The blood levels and effects of caffeine may be enhanced by Ferasiro 180 Tablet. Avoid consumption of caffeinated drinks during the treatment with Ferasiro 180 Tablet. If you experience any unusual symptoms call a doctor.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CHELATING AGENTS]

FAQs

Ferasiro 180 Tablet 10's is used to treat chronic iron overload due to blood transfusions (transfusional hemosiderosis).
Deferasirox is the active component in Ferasiro 180 Tablet 10's. It is a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose. Do not take a double dose to make up for the dose that you missed.
Ferasiro 180 Tablet 10's is safe if used in the dose and duration recommended by your doctor. Take it precisely as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
The extra iron due to iron overload is stored in pancreas. This damages the pancreas and it does not produce insulin properly. Insulin is required by the body to utilise sugar/glucose efficiently. As insulin is not produced properly, it affects blood sugar levels.
Yes, iron overload is the same as haemochromatosis. Hemochromatosis, or iron overload, is a condition in which your body stores too much iron.
Yes, Ferasiro 180 Tablet 10's can be used in children above 2 years if prescribed by the doctor. Talk to the doctor if you have any concerns regarding this.
Ferasiro 180 Tablet 10's may cause side effects like diarrhoea, vomiting, nausea, abdominal pain, skin rashes, and increased serum creatinine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
It depends on the specific tablet type your doctor prescribes. Some formulations of Ferasiro 180 Tablet 10's must be taken on an empty stomach, while others can be taken with a light meal. Check your prescription label or talk to your doctor or pharmacist for specific instructions.
Ferasiro 180 Tablet 10's works gradually over several weeks and months. Your doctor will monitor your blood iron levels regularly to track your progress and see how well the medicine is working. Talk to your doctor or pharmacist to understand your specific treatment timeline.
Avoid taking aluminum-containing antacids, high-dose vitamin C supplements, and drinking excessive alcohol. You should also consult your doctor before taking any new over-the-counter pain relievers or herbal supplements.
Yes, Ferasiro 180 Tablet 10's can affect kidney function in some patients. Your doctor will perform regular blood and urine tests to monitor your kidney health while you are taking this medication. Talk to your doctor or pharmacist if you notice a decrease in urination or swelling in your feet.
It is best to take Ferasiro 180 Tablet 10's at the same time every day to maintain a consistent level of the medication in your body. Choose a time that is easy for you to remember and fits your daily routine.
It is highly recommended to limit or avoid alcohol while taking Ferasiro 180 Tablet 10's. Both alcohol and this medicine can place extra stress on your liver, increasing the risk of liver damage. Talk to your doctor or pharmacist for personalised advice.
The safety of Ferasiro 180 Tablet 10's during pregnancy has not been fully established. If you are pregnant, planning to become pregnant, or breastfeeding, do not start this medication without discussing the risks and benefits with your doctor.
A mild skin rash can sometimes occur. However, because some rashes can become severe, you should contact your doctor immediately if you notice a rash, itching, or skin peeling. Talk to your doctor or pharmacist for advice on managing skin reactions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Msn Laboratories Pvt.Ltd., Msn House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, India
Other Info - FER1442

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