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  3. Defrijet FCT 180 mg Tablet 10's

Defrijet FCT 180 mg Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Defrijet FCT 180 mg Tablet is used to treat iron overload due to transfusional hemosiderosis (the accumulation of iron in the body due to frequent blood transfusions) or non-transfusion-dependent thalassemia (patients who do not require lifelong regular transfusions for survival). It works by binding to the extra iron and facilitates its removal from the body through faeces. In some cases, this medicine may cause side effects like diarrhoea, vomiting, nausea, abdominal pain, and skin rashes.

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Composition :

DEFERASIROX-180MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Defrijet FCT 180 mg Tablet

Defrijet FCT 180 mg Tablet is used for treating chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients two years older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).

The active ingredient in Defrijet FCT 180 mg Tablet is deferasirox, which binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.

In some cases, you may experience common side effects such as diarrhoea, vomiting, nausea, abdominal pain, and skin rashes. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Avoid taking Defrijet FCT 180 mg Tablet if you are allergic to it. Do not use Defrijet FCT 180 mg Tablet without a doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using the Defrijet FCT 180 mg Tablet if you are pregnant or breastfeeding. Do not use Defrijet FCT 180 mg Tablet in more than prescribed doses or for a longer duration as it may cause adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Defrijet FCT 180 mg Tablet to rule out any side effects.

Uses of Defrijet FCT 180 mg Tablet

Defrijet FCT 180 mg Tablet is used for treating chronic iron overload that occurs due to blood transfusions. The detailed uses of Defrijet FCT 180 mg Tablet are as follows:

  • Transfusional hemosiderosis: Used for treating chronic iron overload that occurs due to blood transfusions in patients two years of age and older.
  • Non-transfusion-dependent thalassemia (NTDT): Defrijet FCT 180 mg Tablet can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia.

Directions for Use

  • Defrijet FCT 180 mg Tablet should be taken on an empty stomach, at least 30 minutes before a meal.
  • Follow your doctor's instructions on the dosage and timing of this medication. However, it is suggested to take Defrijet FCT 180 mg Tablet at the same time each day to maintain a consistent level of medicine in your body.
  • Swallow the whole Defrijet FCT 180 mg Tablet with a glass of water.
  • Do not break, chew, or crush it.

Medicinal Benefits

  • Deferasirox is the active component in Defrijet FCT 180 mg Tablet .
  • It's a chelating agent that selectively binds to trivalent iron.
  • It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.

How Defrijet FCT 180 mg Tablet Works

The active ingredient in Defrijet FCT 180 mg Tablet is deferasirox. It is a trivalent iron-selective chelating agent. It binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Defrijet FCT 180 mg Tablet
  • Your doctor may recommend medications to dissolve the small gallstones (like ursodiol) or use shock waves to break up the stones.
  • Try to eat regular meals because skipping meals can increase the risk of gallstones by making your gallbladder work less efficiently.
  • Eat breakfast soon after you wake up, as cholesterol in bile is highest in the morning.
  • If you are overweight, losing weight gradually can help lower the chance of developing gallstones.
  • Include plenty of fresh vegetables and fruits in your diet.
  • Base your meals around starchy foods like bread, pasta, rice, and potatoes, especially whole grain or high-fibre varieties.

What if I have taken an overdose of Defrijet FCT 180 mg Tablet

Do not exceed the recommended dose, as it might cause an overdose. Overdose symptoms may include nausea, abdominal pain, vomiting, diarrhoea, and kidney/liver problems that might be serious. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Defrijet FCT 180 mg Tablet if you are allergic to Defrijet FCT 180 mg Tablet or its ingredients.
  • Defrijet FCT 180 mg Tablet is not usually recommended if you are a pregnant or lactating woman; there is not enough information to say whether it's safe.
  • It is unknown whether Defrijet FCT 180 mg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.
  • Seek medical attention if the symptoms persist longer.
  • Avoid consuming alcohol along with Defrijet FCT 180 mg Tablet as it could lead to unpleasant side effects.
  • Should monitor elderly and paediatric patients closely for toxicity.

Drug-Drug Interactions

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DeferasiroxStreptokinase
Severe
DeferasiroxNaproxen
Severe

Drug-Drug Interactions

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DeferasiroxStreptokinase
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Combining Streptokinase with Defrijet FCT 180 mg Tablet can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Streptokinase with Defrijet FCT 180 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxNaproxen
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Using Defrijet FCT 180 mg Tablet together with Naproxen may increase the risk of gastrointestinal ulcers.

How to manage the interaction:
Co-administration of Naproxen with Defrijet FCT 180 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts. If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxPiroxicam
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Using Defrijet FCT 180 mg Tablet together with Piroxicam may increase the risk of ulcers.

How to manage the interaction:
Co-administration of Piroxicam with Defrijet FCT 180 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxPrednisolone
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Co-administration of Defrijet FCT 180 mg Tablet with Prednisolone can increase the risk of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Although taking Defrijet FCT 180 mg Tablet with Prednisolone together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience stomach pain, bloating, dizziness, lightheadedness, loss of appetite, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools, you should consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DeferasiroxDasatinib
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Coadministration of Defrijet FCT 180 mg Tablet together with Dasatinib may increase the risk of bleeding.

How to manage the interaction:
Although taking Dasatinib and Defrijet FCT 180 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, like stomach pain, feeling dizzy, it's important to call a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxPrednisone
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Using Defrijet FCT 180 mg Tablet together with Prednisone may increase the risk of gastrointestinal ulcers.

How to manage the interaction:
Co-administration of Prednisone with Defrijet FCT 180 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxTenecteplase
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Combining Tenecteplase with Defrijet FCT 180 mg Tablet can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Tenecteplase with Defrijet FCT 180 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxFlurbiprofen
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Taking Flurbiprofen with Defrijet FCT 180 mg Tablet can increase the risk of gastrointestinal bleeding and peptic ulcer.

How to manage the interaction:
Co-administration of Flurbiprofen with Defrijet FCT 180 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxZinc chloride
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Taking zinc acetate with Defrijet FCT 180 mg Tablet can decrease the blood levels of Defrijet FCT 180 mg Tablet.

How to manage the interaction:
Although taking Zinc acetate and Defrijet FCT 180 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. Incase of any side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.
DeferasiroxSulindac
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Combining Sulindac with Defrijet FCT 180 mg Tablet can increase the risk of bleeding and ulcers in the stomach.

How to manage the interaction:
Co-administration of Sulindac with Defrijet FCT 180 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DEFERASIROX-180MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEFERASIROX-180MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
The blood levels and effects of caffeine may be enhanced by Defrijet FCT 180 mg Tablet. Avoid consumption of caffeinated drinks during the treatment with Defrijet FCT 180 mg Tablet. If you experience any unusual symptoms call a doctor.

Diet & Lifestyle Advise

  • Choose foods high in nutrients, such as fruits, vegetables, and whole grains.
  • Replace fatty protein sources with lean alternatives and consume modest quantities of healthy fat sources for improved well-being.
  • Create a diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Instead of saturated and trans fats, choose monounsaturated and polyunsaturated fats (fish, nuts, and vegetable oils).
  • Select/prepare foods and beverages with fewer added sugars/caloric sweeteners.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol and caffeine consumption.

Habit Forming

No

Therapeutic Class

CHELATING AGENTS

Defrijet FCT 180 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Consuming alcohol along with Defrijet FCT 180 mg Tablet is not advisable, as it may cause unpleasant side effects, or you also may become more sensitive to the effects of alcohol.

bannner image

Pregnancy

Consult your doctor

Defrijet FCT 180 mg Tablet is not usually recommended if you are pregnant. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks. Please consult the doctor.

bannner image

Breast Feeding

Consult your doctor

Defrijet FCT 180 mg Tablet is not usually recommended if you are a lactating woman. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks.

bannner image

Driving

Caution

It is not known whether Defrijet FCT 180 mg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react.

bannner image

Liver

Caution

Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Caution

Defrijet FCT 180 mg Tablet should be used under the supervision of healthcare provider

Have a query?

FAQs

Defrijet FCT 180 mg Tablet is used to treat chronic iron overload due to blood transfusions (transfusional hemosiderosis).

Deferasirox is the active component in Defrijet FCT 180 mg Tablet . It is a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.

No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.

Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose. Do not take a double dose to make up for the dose that you missed.

Defrijet FCT 180 mg Tablet is safe if used in the dose and duration recommended by your doctor. Take it precisely as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

The extra iron due to iron overload is stored in pancreas. This damages the pancreas and it does not produce insulin properly. Insulin is required by the body to utilise sugar/glucose efficiently. As insulin is not produced properly, it affects blood sugar levels.

Yes, iron overload is the same as haemochromatosis. Hemochromatosis, or iron overload, is a condition in which your body stores too much iron.

Yes, Defrijet FCT 180 mg Tablet can be used in children above 2 years if prescribed by the doctor. Talk to the doctor if you have any concerns regarding this.

Defrijet FCT 180 mg Tablet may cause side effects like diarrhoea, vomiting, nausea, abdominal pain, skin rashes, and increased serum creatinine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - DEF0270

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 11, 2025 | 11:46 AM IST

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Reference

  1. https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=207968
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/207968s009lbl.pdf

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