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  3. Defrijet FCT 180 mg Tablet 10's

Defrijet FCT 180 mg Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Defrijet FCT 180 mg Tablet is used to treat iron overload due to transfusional hemosiderosis (the accumulation of iron in the body due to frequent blood transfusions) or non-transfusion-dependent thalassemia (patients who do not require lifelong regular transfusions for survival). It works by binding to the extra iron and facilitates its removal from the body through faeces. In some cases, this medicine may cause side effects like diarrhoea, vomiting, nausea, abdominal pain, and skin rashes.
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Composition :

DEFERASIROX-180MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Defrijet FCT 180 mg Tablet

Defrijet FCT 180 mg Tablet is used for treating chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients two years older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).

The active ingredient in Defrijet FCT 180 mg Tablet is deferasirox. It is a trivalent iron selective chelating agent. It binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.

Defrijet FCT 180 mg Tablet is available in the form of oral formulations. Please take Defrijet FCT 180 mg Tablet in the dose and duration prescribed by your doctor based on specific medical conditions. In some cases, you may experience common side effects such as diarrhoea, vomiting, nausea, abdominal pain, skin rashes, and increased serum creatinine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue using Defrijet FCT 180 mg Tablet for as long as your doctor has prescribed it. Do not use Defrijet FCT 180 mg Tablet without a doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using the Defrijet FCT 180 mg Tablet if you are pregnant or breastfeeding. Do not use Defrijet FCT 180 mg Tablet in more than prescribed doses or for a longer duration as it may cause adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Defrijet FCT 180 mg Tablet to rule out any side effects.

Uses of Defrijet FCT 180 mg Tablet

Used for treating chronic iron overload that occurs due to blood transfusions (transfusional hemosiderosis) in patients two years of age and older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).

Directions for Use

• Defrijet FCT 180 mg Tablet should be taken on an empty stomach, at least 30 minutes before a meal.• Follow your doctor's instructions on the dosage and timing of this medication. However, it is suggested to take Defrijet FCT 180 mg Tablet at the same time each day to maintain a consistent level of medicine in your body.• Swallow the whole Defrijet FCT 180 mg Tablet with a glass of water.• Do not break, chew, or crush it.

Medicinal Benefits

Deferasirox is the active component in Defrijet FCT 180 mg Tablet . It's a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.

How Defrijet FCT 180 mg Tablet Works

The active ingredient in Defrijet FCT 180 mg Tablet is deferasirox. It is a trivalent iron selective chelating agent. It binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.

Storage

Keep out of sight and reach of children.
Side effects of Defrijet FCT 180 mg Tablet
  • Your doctor may recommend medications to dissolve the small gallstones (like ursodiol) or use shock waves to break up the stones.
  • Try to eat regular meals because skipping meals can increase the risk of gallstones by making your gallbladder work less efficiently.
  • Eat breakfast soon after you wake up, as cholesterol in bile is highest in the morning.
  • If you are overweight, losing weight gradually can help lower the chance of developing gallstones.
  • Include plenty of fresh vegetables and fruits in your diet.
  • Base your meals around starchy foods like bread, pasta, rice, and potatoes, especially whole grain or high-fibre varieties.

What if I have taken an overdose of Defrijet FCT 180 mg Tablet

Take Defrijet FCT 180 mg Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Overdose symptoms may include nausea, abdominal pain, vomiting, diarrhoea, and kidney/liver problems that might be serious. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Defrijet FCT 180 mg Tablet if you are allergic to Defrijet FCT 180 mg Tablet or its ingredients. Defrijet FCT 180 mg Tablet is not usually recommended if you are a pregnant or lactating woman; there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the medicine's benefits outweigh the risks. It is unknown whether Defrijet FCT 180 mg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer. Avoid consuming alcohol along with Defrijet FCT 180 mg Tablet as it could lead to unpleasant side effects. Should monitor elderly and paediatric patients closely for toxicity.

Drug-Drug Interactions

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DeferasiroxKetoprofen
Severe
DeferasiroxCilostazol
Severe

Drug-Drug Interactions

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DeferasiroxKetoprofen
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Combining Ketoprofen with Defrijet FCT 180 mg Tablet can increase the risk of gastrointestinal bleeding and ulcers.

How to manage the interaction:
Co-administration of Ketoprofen with Defrijet FCT 180 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxCilostazol
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Co-administration of Defrijet FCT 180 mg Tablet with cilostazol can increase the risk or severity of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Taking Defrijet FCT 180 mg Tablet with cilostazol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as stomach pain, bloating, dizziness, lightheadedness, decreased hunger, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools. Do not discontinue any medications without consulting a doctor.
DeferasiroxTicagrelor
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Taking Defrijet FCT 180 mg Tablet together with ticagrelor may increase the risk of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Although taking ticagrelor and Defrijet FCT 180 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as abdominal pain, bloating, dizziness, lightheadedness, loss of hunger, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools. Do not stop using any medications without consulting doctor.
DeferasiroxLithium
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Taking Defrijet FCT 180 mg Tablet with lithium may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Lithium and Defrijet FCT 180 mg Tablet, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, palpitations and confusion. Do not discontinue any medications without consulting a doctor.
DeferasiroxRisedronic acid
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Taking Risedronic acid (oral form) with Defrijet FCT 180 mg Tablet can increase the risk of bleeding and ulcers in the stomach.

How to manage the interaction:
Taking Risedronic acid with Defrijet FCT 180 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of hunger, or black, tarry stools. Do not discontinue any medications without consulting a doctor.
DeferasiroxTobramycin
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Taking Defrijet FCT 180 mg Tablet with tobramycin may increase the risk of kidney problems.

How to manage the interaction:
Taking Tobramycin with Defrijet FCT 180 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without talking to your doctor.
DeferasiroxAminophylline
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Combining Aminophylline with Defrijet FCT 180 mg Tablet may significantly increase the blood levels of aminophylline.

How to manage the interaction:
Taking Aminophylline with Defrijet FCT 180 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, diarrhea, loss of appetite, headache, confusion, restlessness, sleeplessness, fits, heart palpitations, or irregular heartbeat contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeferasiroxTriamcinolone
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Using Defrijet FCT 180 mg Tablet together with triamcinolone may increase the risk of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Although there is a possible interaction between Defrijet FCT 180 mg Tablet and triamcinolone, you can take these medicines together if prescribed by your doctor. However, if you experience abdominal pain, bloating, dizziness, lightheadedness, loss of appetite, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools, contact your doctor right away. Do not discontinue any medications without consulting your doctor.
DeferasiroxBivalirudin
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Using Defrijet FCT 180 mg Tablet together with bivalirudin may increase the risk of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Co-administration of Bivalirudin with Defrijet FCT 180 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxZinc chloride
Severe
How does the drug interact with Defrijet FCT 180 mg Tablet:
Taking zinc acetate with Defrijet FCT 180 mg Tablet can decrease the blood levels of Defrijet FCT 180 mg Tablet.

How to manage the interaction:
Although taking Zinc acetate and Defrijet FCT 180 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. Incase of any side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DEFERASIROX-180MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEFERASIROX-180MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
The blood levels and effects of caffeine may be enhanced by Defrijet FCT 180 mg Tablet. Avoid consumption of caffeinated drinks during the treatment with Defrijet FCT 180 mg Tablet. If you experience any unusual symptoms call a doctor.

Diet & Lifestyle Advise

  • Choose foods high in nutrients, such as fruits, vegetables, and whole grains.

  • Replace fatty protein sources with lean alternatives and consume modest quantities of healthy fat sources for improved well-being.

  • Create a diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.

  • Instead of saturated and trans fats, choose monounsaturated and polyunsaturated fats (fish, nuts, and vegetable oils).

  • Select/prepare foods and beverages with fewer added sugars/caloric sweeteners.

  • Be mindful of salt; consume no more than 2,300 mg each day.

  • Limit or avoid alcohol and caffeine consumption.

Habit Forming

No

Therapeutic Class

CHELATING AGENTS

Defrijet FCT 180 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Consume alcohol along with Defrijet FCT 180 mg Tablet is not advisable as it may cause unpleasant side effects, or you also may become more sensitive to the effects of alcohol.

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Pregnancy

Caution

Defrijet FCT 180 mg Tablet is not usually recommended if you are pregnant. This is because there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks. Please consult the doctor.

bannner image

Breast Feeding

Caution

Defrijet FCT 180 mg Tablet is not usually recommended if you are a lactating woman. This is because there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks.

bannner image

Driving

Caution

It is not known whether Defrijet FCT 180 mg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react.

bannner image

Liver

Caution

Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Caution

Should be used under the supervision of healthcare provider

Have a query?

FAQs

Defrijet FCT 180 mg Tablet is used to treat chronic iron overload due to blood transfusions (transfusional hemosiderosis).

Deferasirox is the active component in Defrijet FCT 180 mg Tablet . It's a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.

No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.

Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose. Do not take a double dose to make up for the dose that you missed.

Defrijet FCT 180 mg Tablet is safe if used in the dose and duration recommended by your doctor. Take it precisely as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

The extra iron due to iron overload is stored in pancreas. This damages the pancreas and it does not produce insulin properly. Insulin is required by the body to utilise sugar/glucose efficiently. As insulin is not produced properly, it affects blood sugar levels.

Yes, iron overload is the same as haemochromatosis. Hemochromatosis, or iron overload, is a condition in which your body stores too much iron.

Yes, Defrijet FCT 180 mg Tablet can be used in children above 2 years if prescribed by the doctor. Talk to the doctor if you have any concerns regarding this.

Defrijet FCT 180 mg Tablet may cause side effects like diarrhoea, vomiting, nausea, abdominal pain, skin rashes, and increased serum creatinine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - DEF0270

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:54 AM IST

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Reference

  1. https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=207968
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/207968s009lbl.pdf

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