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compositionComposition:ADALIMUMAB-40MG
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Exemptia 40 mg Injection 0.8 ml is used to help reduce signs and symptoms of autoimmune disorders such as Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn's disease, Uveitis and Ulcerative colitis. It consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ADALIMUMAB-40MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Exemptia 40 mg Injection 0.8 ml

Exemptia 40 mg Injection 0.8 ml is an injectable prescription medicine used to reduce chronic inflammation in the body. It is clinically approved to treat several autoimmune conditions, including rheumatoid arthritis, plaque psoriasis, Crohn's disease, and ulcerative colitis. By targeting the source of swelling and pain, this medicine helps manage symptoms and prevent further tissue damage.

For best results, you must inject Exemptia 40 mg Injection 0.8 ml consistently on the schedule prescribed by your doctor. Because it is given as a subcutaneous injection, you can take it with or without food. To support your treatment, incorporating lifestyle changes such as a nutrient-dense diet and low-impact exercise can help manage your symptoms and improve overall mobility.

While using Exemptia 40 mg Injection 0.8 ml, you may experience mild side effects, such as pain or redness at the injection site, headache, or cold symptoms. However, you must contact your doctor immediately if you experience serious side effects, including signs of infection like a high fever, severe skin rashes, or yellowing of the skin or eyes.

Before starting treatment, tell your doctor if you have a history of tuberculosis, frequent infections, heart failure, or nervous system disorders. Do not take this medicine if you currently have a severe active infection. Your doctor will run blood tests to ensure it is safe for you to start.

This medicine can interact with other treatments, such as live vaccines and other biologic drugs, which can increase your risk of severe infections. It is also important to talk to your doctor or pharmacist if you are pregnant, breastfeeding, or are an older adult, as special precautions may be needed.

Uses of Exemptia 40 mg Injection 0.8 ml

Exemptia 40 mg Injection 0.8 ml is used to treat autoimmune and inflammatory conditions. Your doctor may prescribe it for the following conditions:

  • Rheumatoid arthritis: Exemptia 40 mg Injection 0.8 ml helps reduce joint pain, stiffness, and swelling in adults with moderate to severe rheumatoid arthritis, helping to prevent joint damage.
  • Plaque psoriasis: It is used to treat moderate to severe plaque psoriasis by reducing itchy, scaly skin patches and improving overall skin appearance.
  • Crohn's disease: This medicine reduces inflammation in the digestive tract, helping to control symptoms like abdominal pain and chronic diarrhea.
  • Ulcerative colitis: It helps control inflammation in the large intestine, allowing the bowel lining to heal and helping to achieve long-term remission.
  • Ankylosing spondylitis: It helps reduce inflammation in the spine and joints, easing back pain and improving physical flexibility.

Key Benefits

Using Exemptia 40 mg Injection 0.8 ml as prescribed helps reduce inflammation and improve symptoms of autoimmune and inflammatory conditions. Here are the key benefits you can expect:

  • Relieves pain and inflammation: Helps reduce joint pain, stiffness, and swelling, making everyday movements more comfortable.
  • Supports digestive health: Helps heal the lining of the digestive tract, reducing flare-ups, abdominal pain, and improving digestive stability in inflammatory bowel disease.
  • Improves skin health: Helps clear red, scaly skin patches, relieving itching and discomfort associated with plaque psoriasis.
Side effects of Exemptia 40mg/0.8ml Inj
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Exemptia 40 mg Injection 0.8 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Exemptia 40 mg Injection 0.8 ml Works

Exemptia 40 mg Injection 0.8 ml contains adalimumab, a monoclonal antibody that helps treat autoimmune and inflammatory conditions. It works by targeting and blocking a protein called tumour necrosis factor (TNF), which plays a key role in causing inflammation. In autoimmune diseases, the body produces too much TNF, leading the immune system to attack healthy tissues. By binding to excess TNF, Exemptia 40 mg Injection 0.8 ml blocks the inflammatory signals responsible for swelling and tissue damage. This helps reduce inflammation, relieve symptoms, protect joints and other affected tissues, and improve overall disease control.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Exemptia 40 mg Injection 0.8 ml. Please consult the doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Exemptia 40 mg Injection 0.8 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Exemptia 40 mg Injection 0.8 ml.

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Driving

Caution

Exemptia 40 mg Injection 0.8 ml will be administered in the hospital setting. Hence, driving is not recommended.

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Liver

Caution

Exemptia 40 mg Injection 0.8 ml should be used with caution if you have liver disease. Dose adjustment may be needed in patients with liver impairment.

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Kidney

Caution

Exemptia 40 mg Injection 0.8 ml should be used with caution if you have kidney disease. Dose adjustment may be needed in patients with liver impairment.

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Children

Caution

Exemptia 40 mg Injection 0.8 ml is not recommended in children below two years of age as safety and efficacy are not established. In children above two years of age, it will be administered by the pediatrician. Exemptia 40 mg Injection 0.8 ml is used in children only for the treatment of juvenile idiopathic arthritis, paediatric Crohn’s disease, and uveitis.

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Heart

Caution

Exemptia 40 mg Injection 0.8 ml may not be safe for heart patients. Therefore, please inform your doctor if you have any pre-existing heart conditions.

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Geriatrics

Consult your doctor

Limited information available about the use of Exemptia 40 mg Injection 0.8 ml in geriatric patients. Please consult your physician.

What if I have taken an overdose of Exemptia 40 mg Injection 0.8 ml

If you accidentally inject more than your prescribed dose, seek immediate medical attention or call an emergency health service right away, even if you do not feel any symptoms.

Diet & Lifestyle Advise

  • Practice excellent hygiene: Because this medicine lowers your body's ability to fight infections, wash your hands frequently with soap and water, and avoid close contact with people who are sick.
  • Avoid raw or undercooked foods: Protect yourself from foodborne illnesses by avoiding raw meats, raw seafood, and unpasteurized dairy products, as your immune system is less active.
  • Stay active with gentle exercise: If you are treating joint conditions, engage in low-impact physical activities like swimming, cycling, or walking to keep joints flexible and reduce stiffness.
  • Identify food triggers: If you are treating Crohn's disease or ulcerative colitis, keep a food diary to identify foods that trigger flares, and focus on a diet rich in easy-to-digest nutrients.
  • Protect your skin: Wear sunscreen and protective clothing outdoors, as some inflammatory skin conditions can become more sensitive during treatment.
health query

Have a query?

How Soon It Starts Working

The time required for Exemptia 40 mg Injection 0.8 ml to start to work: The exact onset of time for Exemptia 40 mg Injection 0.8 ml is unknown. The time for which the effects of Exemptia 40 mg Injection 0.8 ml last: The duration of Exemptia 40 mg Injection 0.8 ml’s effect is clinically not established.

What if you forget to take Exemptia 40 mg Injection 0.8 ml

If you miss a dose of Exemptia 40 mg Injection 0.8 ml, inject it as soon as you remember. However, if your next scheduled dose is coming up soon, skip the missed dose and return to your regular schedule. Do not inject a double dose to make up for a missed one. If you are unsure what to do, talk to your doctor or pharmacist.

Storage

• Store Exemptia 40 mg Injection 0.8 ml in the refrigerator at 2°C–8°C (36°F–46°F) in its original carton to protect it from light.

Drug Warnings

  • Check before use: Inspect the liquid in the syringe or pen before injecting. It should be clear and colourless to pale yellow. Do not use it if it is cloudy, discoloured, or contains visible particles.
  • Do not reuse needles or syringes: Dispose of used needles and syringes immediately in an approved puncture-resistant sharps container.
  • Avoid live vaccines: Do not receive live vaccines, such as live influenza or shingles vaccines, while taking Exemptia 40 mg Injection 0.8 ml, as they may increase the risk of serious infections.
  • Inform healthcare professionals: Tell your doctor, dentist, surgeon, and other healthcare professionals that you are taking Exemptia 40 mg Injection 0.8 ml before undergoing any medical or dental procedures.
  • Keep an injection record: Maintain a written log of your injection dates, times, and injection sites to help ensure proper rotation of injection locations.

Drug-Drug Interactions

verifiedApollotooltip
  • Biologic medicines: Taking Exemptia 40 mg Injection 0.8 ml alongside other biologic drugs (such as abatacept, anakinra, or rituximab) can significantly increase your risk of severe, life-threatening infections.
  • Live vaccines: Combining this medicine with live vaccines can cause active infections from the vaccine virus because your immune response is lowered.
AdalimumabCarfilzomib
Severe
AdalimumabHydrocortisone
Severe

Drug-Drug Interactions

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AdalimumabCarfilzomib
Severe
How does the drug interact with Exemptia 40mg/0.8ml Inj:
Combining Exemptia 40mg/0.8ml Inj with Carfilzomib can increase the risk of infections.

How to manage the interaction:
Co-administration of Carfilzomib with Exemptia 40mg/0.8ml Inj can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination. Do not stop using any medications without first talking to your doctor.
AdalimumabHydrocortisone
Severe
How does the drug interact with Exemptia 40mg/0.8ml Inj:
Co-administration of Exemptia 40mg/0.8ml Inj and hydrocortisone together can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Exemptia 40mg/0.8ml Inj and hydrocortisone can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
AdalimumabIbrutinib
Severe
How does the drug interact with Exemptia 40mg/0.8ml Inj:
Co-administration of Ibrutinib and Exemptia 40mg/0.8ml Inj can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Ibrutinib can be taken with Exemptia 40mg/0.8ml Inj, if prescribed by the doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
AdalimumabTemozolomide
Severe
How does the drug interact with Exemptia 40mg/0.8ml Inj:
Using Exemptia 40mg/0.8ml Inj together with temozolomide may increase the risk of serious infections.

How to manage the interaction:
Although taking temozolomide and Exemptia 40mg/0.8ml Inj together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
AdalimumabValganciclovir
Severe
How does the drug interact with Exemptia 40mg/0.8ml Inj:
The combined use of Exemptia 40mg/0.8ml Inj and valganciclovir can increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Valganciclovir and Exemptia 40mg/0.8ml Inj, but it can be taken if prescribed by a doctor. If you notice any of the following symptoms - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - reach out to your doctor right away. Do not stop using any medications without talking to your doctor.
AdalimumabMercaptopurine
Severe
How does the drug interact with Exemptia 40mg/0.8ml Inj:
When Exemptia 40mg/0.8ml Inj is taken with Mercaptopurine, the effect of Mercaptopurine in the blood may decrease which may increase risk of infection.

How to manage the interaction:
Taking Mercaptopurine with Exemptia 40mg/0.8ml Inj together can possibly result in an interaction, but it can be taken if a doctor has advised it. However contact a doctor immediately, if you experience any symptoms such as infections, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning during urination. Do not discontinue any medications without consulting a doctor.
AdalimumabCarboplatin
Severe
How does the drug interact with Exemptia 40mg/0.8ml Inj:
Using Exemptia 40mg/0.8ml Inj with Carboplatin can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Carboplatin and Exemptia 40mg/0.8ml Inj together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
AdalimumabNilotinib
Severe
How does the drug interact with Exemptia 40mg/0.8ml Inj:
Using Exemptia 40mg/0.8ml Inj and nilotinib together can increase the risk of developing infections.

How to manage the interaction:
Combining Exemptia 40mg/0.8ml Inj and nilotinib can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, body sores, and pain or burning during urination, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
AdalimumabLeflunomide
Severe
How does the drug interact with Exemptia 40mg/0.8ml Inj:
Taking Exemptia 40mg/0.8ml Inj with leflunomide can increase the risk of side effects.

How to manage the interaction:
Although taking Leflunomide and Exemptia 40mg/0.8ml Inj together can cause an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, pain or burning during urination. Do not discontinue any medications without consulting a doctor.
AdalimumabCapecitabine
Severe
How does the drug interact with Exemptia 40mg/0.8ml Inj:
Co-administration of Capecitabine is taken with Exemptia 40mg/0.8ml Inj, which may increase the risk or severity of infections.

How to manage the interaction:
There may be a possibility of interaction between Capecitabine and Exemptia 40mg/0.8ml Inj, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include an enlarged spleen or liver, stomach pain, ongoing fever, excessive sweating at night, unexplained weight loss, complications, infection, fever, chills, diarrhea, a sore throat, muscle aches, difficulty breathing, or pain or discomfort while urinating. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Exemptia 40 mg Injection 0.8 ml when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

[IMMUNOSUPPRESSANTS]

FAQs

Exemptia 40 mg Injection 0.8 ml is used to treat rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, Crohn's disease, uveitis, and ulcerative colitis. By reducing inflammation, it helps relieve pain, swelling, redness, stiffness, and other symptoms associated with these autoimmune conditions.
Exemptia 40 mg Injection 0.8 ml contains adalimumab, an antirheumatic medicine belonging to the TNF inhibitor class. It works by blocking TNF-α, a protein that causes inflammation, helping reduce inflammation and symptoms of autoimmune diseases.
Exemptia 40 mg Injection 0.8 ml affects your immune system and makes you more susceptible to infections. Hence, it is not recommended in people with active infections like tuberculosis or abnormal liver enzymes. Exemptia 40 mg Injection 0.8 ml can also increase the risk of developing cancers; hence, informing your doctor if you have a history of any cancer is essential.
Treatment with Exemptia 40 mg Injection 0.8 ml can help reduce inflammation, pain, redness, and swelling associated with various autoimmune disorders.
Exemptia 40 mg Injection 0.8 ml which contains Adalimumab, can weaken your immune system. Since it affects the immune system, it may increase your risk of developing infections. It is important to follow your doctor's advice and inform them if you have any existing infections or health concerns before starting treatment.
Exemptia 40 mg Injection 0.8 ml can be used alongside other arthritis medicines such as methotrexate, prednisolone, naproxen, ibuprofen, and paracetamol. However, Exemptia 40 mg Injection 0.8 ml should not be used with other biological disease-modifying antirheumatic drugs (bDMARDs).
Exemptia 40 mg Injection 0.8 ml should be stopped before surgery. It can be resumed after the operation, once the wound has healed and there is no infection, as determined by your surgeon and rheumatologist.
Exemptia 40 mg Injection 0.8 ml causes side effects such as rash, headache, sinusitis, upper respiratory infections, fever, and application site reactions. Therefore, please contact a doctor if these do not reduce and persist for longer durations.
Yes, you can travel with Exemptia 40 mg Injection 0.8 ml. It can be stored at room temperature up to 77°F (25°C) for up to 14 days, but it must be protected from light and kept from freezing. Talk to your doctor or pharmacist about travel cases and airport security documentation.
Yes, your doctor will perform a tuberculosis (TB) skin or blood test and check for hepatitis B before you start treatment. They will also monitor your blood counts during therapy. Talk to your doctor about these safety tests.
There is no direct interaction between alcohol and Exemptia 40 mg Injection 0.8 ml. However, alcohol can increase liver strain or trigger flares for conditions like psoriasis or inflammatory bowel disease. Talk to your doctor to see if drinking alcohol is safe for you.
Because Exemptia 40 mg Injection 0.8 ml lowers your immune response, even a mild cold can sometimes turn into a more serious infection. Contact your doctor immediately if you develop a fever, persistent cough, or cold symptoms, as you may need to pause your injections. Talk to your doctor for guidance.
Yes, you can get the standard injectable flu shot, which is an inactive vaccine. However, you must avoid live vaccines, such as the nasal spray flu vaccine, while on this treatment. Talk to your doctor before scheduling any vaccines.
Exemptia 40 mg Injection 0.8 ml should only be used during pregnancy or breastfeeding if the benefits outweigh the risks. If you are pregnant, breastfeeding, or planning to have a baby, talk to your doctor to make an informed decision.
No, you should rotate your injection sites with every dose. Injecting into the same spot repeatedly can cause skin thickening, bruising, or pain. Use your abdomen or thighs, and ensure the new spot is at least one inch from the last one. Talk to your doctor or pharmacist if you need help with injection techniques.

Disclaimer

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Reference

  1. U.S. Food and Drug Administration (FDA). 125057S410Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. MedlinePlus. A603010 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  3. DrugBank Online. Db00051 Clinical & Chemical Summary. Edmonton, AB: DrugBank; 2026. [Accessed on 02 Jun. 2026]Check here
  4. National Health Service (NHS). Adalimumab - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  5. Adalimumab Adalimumab. 2002. [Accessed on 25 Jan. 2019]Check here
  6. Adalimumab Adalimumab. 2002. [Accessed on 02 Apr. 2019]Check here
  7. Carter R. Ellis; Chaudhary Ehtsham Azmat. Adalimumab. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. December 2022. [Accessed on 27th March 2023]Check here

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad 380015 Gujarat, India.
Other Info - EXE0098
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