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Epcure-Plus Tablet is used to relieve pain due to muscle spasms. It works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Additionally, it blocks the effect of chemical messengers that cause pain and inflammation. In some cases, this medicine may cause side effects such as nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhoea.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ACECLOFENAC-100MG+EPERISONE-75MG+PARACETAMOL-325MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Epcure-Plus Tablet

Epcure-Plus Tablet is an oral medication prescribed to treat painful muscle spasms and acute musculoskeletal pain. It helps relieve discomfort caused by severe muscle stiffness, joint pain, and lower back pain. By targeting both muscle tension and swelling, it restores comfortable physical movement.

You should take this medicine exactly as prescribed by your doctor, usually once or twice daily depending on your condition. To protect your stomach, always take Epcure-Plus Tablet with food or immediately after a meal. Combining this treatment with gentle stretching, adequate rest, and proper hydration can significantly improve your recovery.

While taking Epcure-Plus Tablet, some people may experience mild side effects such as nausea, dizziness, or mild stomach upset. However, if you experience severe symptoms like dark stools, severe stomach pain, or yellowing of your skin or eyes, you must stop taking the medicine and seek immediate medical attention.

Talk to your doctor before starting Epcure-Plus Tablet if you have a history of stomach ulcers, kidney problems, or heart conditions. Do not take this if you have severe liver damage, active bleeding disorders or if you have ever had an allergic reaction to pain relievers.

This medicine can interact with alcohol, blood thinners, and other pain relievers, which may increase your risk of stomach bleeding or liver damage. Pregnant women, breastfeeding mothers, and elderly individuals should consult their doctor before taking Epcure-Plus Tablet to ensure it is safe for them.

Uses of Epcure-Plus Tablet

Epcure-Plus Tablet is used to treat painful muscle spasms and acute musculoskeletal pain. The detailed uses of Epcure-Plus Tablet are as follows:

  • Painful muscle spasms: Epcure-Plus Tablet helps by relaxing tight skeletal muscles and blocking the pain signals sent to the brain, providing rapid relief from painful cramps.
  • Acute lower back pain: Epcure-Plus Tablet reduces severe inflammation and swelling in the muscles and tissues surrounding the lower spine, making it easier to bend and move.
  • Musculoskeletal pain: Epcure-Plus Tablet targets joint and muscle discomfort caused by injuries, strains, or chronic conditions, allowing the body to heal with less discomfort.

Key Benefits

Epcure-Plus Tablet provides effective relief from muscle pain and stiffness by combining a muscle relaxant with pain-relieving medicines. With regular use, it helps reduce discomfort, restore movement, and support a faster return to daily activities.

  • Relieves Muscle Pain and Stiffness: By relaxing tight muscles and reducing pain, this medicine helps ease muscle spasms, stiffness, and discomfort, improving overall comfort.
  • Restores Mobility: This medicine helps improve your range of motion, making it easier to perform daily activities and participate in physical therapy or rehabilitation exercises.
  • Convenient Combination Therapy: By combining a muscle relaxant with pain-relieving medicines in a single formulation, this medicine provides comprehensive relief while reducing the need to take multiple separate medications.

Directions for Use

  • Epcure-Plus Tablet can be taken with or without food. However, taking it after a meal may help reduce stomach upset.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow the whole Epcure-Plus Tablet with a glass of water.
  • Do not crush, chew, or break it.

How Epcure-Plus Tablet Works

Epcure-Plus Tablet works through a combination of three active components that target pain and muscle tension from different angles. The first component, aceclofenac, is a targeted anti-inflammatory pain reliever. It works by blocking the production of specific chemical messengers in the body, known as prostaglandins, which cause pain, swelling, and inflammation at the site of muscle injury. The second component, eperisone, is a centrally acting muscle relaxant. It acts directly on the brain and spinal cord to relax tight skeletal muscles. It also improves blood circulation within the affected muscles, which helps relieve stiffness and spasms. The third component, paracetamol, is an everyday pain and fever reducer. It works in the central nervous system to elevate the body's pain threshold, making you less sensitive to painful sensations. Together, these three components provide highly effective, synchronised relief.
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Alcohol

Caution

Avoid consumption of alcohol while taking Epcure-Plus Tablet as it may increase drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Epcure-Plus Tablet; your doctor will decide whether Epcure-Plus Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Epcure-Plus Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Consult your doctor before taking Epcure-Plus Tablet if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Consult your doctor before taking Epcure-Plus Tablet if you have kidney impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

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Children

Caution

Epcure-Plus Tablet should not be given to children as the safety and effectiveness were not established.

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Heart

Unsafe

Epcure-Plus Tablet is contraindicated in patients with heart conditions. Please seek medical advice before using this medicine.

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Geriatrics

Caution

Epcure-Plus Tablet should be used with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Epcure-Plus Tablet.

What if I have taken an overdose of Epcure-Plus Tablet

In case of an accidental overdose, seek immediate medical attention. Overdosing can lead to serious health complications, including severe liver damage or extreme drowsiness.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day to help flush the medication through your kidneys and keep your muscles hydrated, which reduces spasms.
  • Apply gentle heat or cold packs: Using a warm compress or ice pack on the affected muscle for 15-20 minutes can complement the medication's effects and speed up muscle relaxation.
  • Incorporate light stretching: Engage in low-impact physical movements or stretching exercises recommended by a physiotherapist to prevent muscle stiffness from returning.
  • Avoid heavy lifting: Protect your muscles and spine by avoiding strenuous physical activity, sudden twisting movements, or heavy lifting while recovering.
  • Eat stomach-friendly foods: Since this medication can sometimes cause mild stomach irritation, stick to bland, non-spicy foods if you experience minor indigestion.
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How Soon It Starts Working

The time required for Epcure-Plus Tablet to start to work: Epcure-Plus Tablet shows its action within 30 to 60 minutes of administration. The time for which the effects of Epcure-Plus Tablet last: Epcure-Plus Tablet effect lasts for 8 to 12 hours.

What if you forget to take Epcure-Plus Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Epcure-Plus Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Avoid driving, operating heavy machinery, or performing tasks that require mental alertness until you know how Epcure-Plus Tablet affects you, as it can cause dizziness or drowsiness.
  • Always check the packaging of other over-the-counter pain, cold, or cough medicines to ensure they do not contain similar pain relievers, preventing an accidental double dose.
  • Limit or entirely avoid alcohol while taking this medicine, as the combination significantly increases the risk of severe stomach bleeding and liver damage.
  • Inform any surgeon or dentist that you are taking Epcure-Plus Tablet before undergoing any scheduled surgical or dental procedures.

verifiedApollotooltip
  • Blood Thinners and Other Anti-Inflammatory Medicines: Taking Epcure-Plus Tablet with blood thinners, such as warfarin, or other anti-inflammatory medicines may significantly increase the risk of stomach ulcers, bleeding, and other bleeding complications.
  • Blood Pressure Medicines: Epcure-Plus Tablet may reduce the effectiveness of blood pressure medicines, including ACE inhibitors and diuretics, making it more difficult to control your blood pressure. Your doctor may monitor your blood pressure and kidney function during treatment.
  • Immunosuppressant Medicines: Combining Epcure-Plus Tablet with immunosuppressant medicines such as cyclosporine or tacrolimus may increase the risk of kidney damage. Your doctor may recommend regular kidney function tests while you are taking these medicines together.

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verifiedApollotooltip
  • Alcohol: Drinking alcohol while taking Epcure-Plus Tablet can significantly increase the risk of liver damage, stomach irritation, ulcers, and gastrointestinal bleeding. It is best to avoid alcohol during treatment.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Epcure-Plus Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, bone and joint pain.
Epcure-Plus Tablet contains Eperisone, Aceclofenac, and Paracetamol. Eperisone works on the spinal cord and brain centres. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac and Paracetamol work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes, thereby reducing mild to moderate pain and inflammation at the injured or damaged site.
Epcure-Plus Tablet is generally prescribed for short-term relief of painful musculoskeletal conditions, including arthritis and muscle spasms. Do not take it for longer than prescribed unless advised by your doctor. If long-term treatment is necessary, your doctor may monitor your liver function, kidney function, and blood counts to reduce the risk of complications.
Epcure-Plus Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
Epcure-Plus Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.
In some cases, Aceclofenac in Epcure-Plus Tablet may cause increased liver enzymes in the blood. Your doctor may monitor the liver enzyme levels during and after the treatment.
No, it is highly recommended to take Epcure-Plus Tablet with food, a meal, or a glass of milk to protect your stomach lining and prevent indigestion. Talk to your doctor or pharmacist if you experience persistent stomach discomfort.
Yes, Epcure-Plus Tablet contains a muscle relaxant component that can cause drowsiness, sleepiness, or lightheadedness in some individuals. It is best to avoid driving or operating machinery until you know how this medicine affects you. Talk to your doctor if this interferes with your daily routines.
Consult your doctor before taking Epcure-Plus Tablet with any other medicines, including over-the-counter pain relievers. Some pain medicines may contain similar ingredients, increasing the risk of side effects such as stomach bleeding, liver damage, or overdose. In addition, Epcure-Plus Tablet may affect the absorption of some orally administered medicines. Always check with your doctor or pharmacist before combining medications.
Epcure-Plus Tablet is generally not recommended for use during pregnancy, especially during the third trimester, as it may harm the unborn baby or cause complications during delivery. Always talk to your doctor to weigh the risks and benefits.
No, you should avoid alcohol while on this medication. Alcohol significantly increases the risk of liver damage and severe stomach bleeding when combined with the active components of Epcure-Plus Tablet. Talk to your doctor if you find it difficult to avoid alcohol.
Stop taking the medicine immediately and seek urgent medical attention. A skin rash can be an early sign of a severe allergic reaction. Talk to your doctor as soon as possible.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Health Service (NHS). Paracetamol For Adults - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Aceclofenac and Paracetamol Tablets B.P. 100mg/325mg (Acetaj P). [Accessed on 02 Jun. 2026]Check here
  4. Ministry of Health and Family Welfare. National Formulary of India (NFI) 2021. 6th ed. New Delhi, India: IPC; 2021. Clinical Drug Monographs: Acemyoset P Tablet
  5. Kruidering-Hall K, Campbell L Skeletal Muscle Relaxants. Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 451-468

Country of origin

India
Other Info - EP35127
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