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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Enzocort Oral Suspension is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. It contains Deflazacort, which binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. It makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy. Some people may experience side effects such as nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DEFLAZACORT-6MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Enzocort Oral Suspension

Enzocort Oral Suspension is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally and is unable to distinguish between foreign cells and native cells. This condition results in an immune system that starts to attack native cells and organs, leading to medical problems like Duchenne muscular dystrophy.

Enzocort Oral Suspension is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Enzocort Oral Suspension binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines, which are responsible for inflammation. Thus, Enzocort Oral Suspension is beneficial in autoimmune diseases and inflammation that cause harm to various organs, especially in joints with arthritis and the skin in psoriasis. Enzocort Oral Suspension makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy.

Enzocort Oral Suspension is available in both oral tablet and suspension dosage forms. The tablet form of Enzocort Oral Suspension can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Enzocort Oral Suspension can be taken as directed by your doctor, using a measuring cup. Your doctor will recommend how often you take Enzocort Oral Suspension based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headaches, dizziness, skin rashes, tremors, nervousness, diarrhoea, and fast heartbeats. Most of the side effects of Enzocort Oral Suspension do not require medical attention and usually resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, stomach upset, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may occur when the medication is stopped suddenly.

Before starting Enzocort Oral Suspension, please inform your doctor that you are allergic or hypersensitive to Enzocort Oral Suspension. Extra care is needed when a patient has an existing infection being treated (systemic infection) or has recently received live virus vaccines. A doctor's consultation is required as Enzocort Oral Suspension is not safe to use during pregnancy.

Uses of Enzocort Oral Suspension

Enzocort Oral Suspension used in the treatment of Duchenne muscular dystrophy (DMD). The detailed uses of Enzocort Oral Suspension are as follows: <br/>• Treatment of DMD: Enzocort Oral Suspension used to treat Duchenne muscular dystrophy by slowing muscle degeneration, preserving strength, and improving mobility.<br/>• Anti-Inflammatory Treatment: Enzocort Oral Suspension reduces inflammation and relieves symptoms associated with conditions like arthritis, bursitis, and tendinitis.<br/>• Autoimmune Disorders Management: Enzocort Oral Suspension helps to manage autoimmune diseases like lupus and multiple sclerosis by suppressing the immune response.<br/>• Relief from Allergic Reactions: Enzocort Oral Suspension provides relief from symptoms of allergic reactions, such as allergic rhinitis, by reducing inflammation and immune response.<br/>• Managing Respiratory Conditions: Enzocort Oral Suspension is also involved in managing respiratory conditions like asthma and COPD by reducing airway inflammation.<br/>• Skin Disorders Treatment: Enzocort Oral Suspension treats skin conditions like eczema and psoriasis by reducing inflammatory responses.<br/>

Directions for Use

• Enzocort Oral Suspension can be taken with or without food.• It is usually taken once daily at the same time each day or as prescribed by your doctor.• Swallow Enzocort Oral Suspension as a whole with a glass of water.• Do not crush or chew this medication.• If you cannot swallow the tablet as a whole, you may break it in half and take both halves separately.

Medicinal Benefits

Enzocort Oral Suspension is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Enzocort Oral Suspension is a steroid that interacts with overactive immune cells, slows their activity, and decreases the damaging effects they cause in the body. 

How Enzocort Oral Suspension Works

Enzocort Oral Suspension is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Enzocort Oral Suspension binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines, which are responsible for inflammation. Thus, Enzocort Oral Suspension is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis, skin, and psoriasis. Enzocort Oral Suspension makes organ transplantation possible, and treats muscle disorders like Duchenne muscular dystrophy.
Side effects of Enzocort Oral Suspension 30 ml
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Drink six to eight glasses of water per day to be healthy.
  • Healthy urinary habits can help minimize pollakiuria (frequent urinating).
  • Avoid liquids containing caffeine, artificial sweeteners, and soda, as they might cause bladder discomfort.
  • Add bladder-friendly foods such as omega-3 fatty acids, blueberries, and cranberries.
  • Regular cleansing will help get rid of dead skin cells and stop ingrown hairs.
  • Keep your hormones in balance by managing your stress, eating well and exercising regularly.
  • Shaving, waxing, and bleaching are ways to get rid of extra hair.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Enzocort Oral Suspension

Do not take more than the prescribed dose of Enzocort Oral Suspension as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney and liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Enzocort Oral Suspension.  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Enzocort Oral Suspension. Before taking Enzocort Oral Suspension for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug-Drug Interactions

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DeflazacortGolimumab
Severe

Drug-Drug Interactions

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How does the drug interact with Enzocort Oral Suspension 30 ml:
Co-administration of Enzocort Oral Suspension 30 ml and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
DeflazacortGolimumab
Severe
How does the drug interact with Enzocort Oral Suspension 30 ml:
Golimumab can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Enzocort Oral Suspension 30 ml.

How to manage the interaction:
Although there is an interaction, Golimumab can be taken with Enzocort Oral Suspension 30 ml if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Enzocort Oral Suspension 30 ml:
Taking Bosentan with Enzocort Oral Suspension 30 ml may significantly reduce the blood levels of Enzocort Oral Suspension 30 ml, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Bosentan and Enzocort Oral Suspension 30 ml together can result in an interaction, they can be taken together if advised by your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Enzocort Oral Suspension 30 ml:
Gemifloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Enzocort Oral Suspension 30 ml.

How to manage the interaction:
Although there is an interaction, Gemifloxacin can be taken with Enzocort Oral Suspension 30 ml if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Enzocort Oral Suspension 30 ml:
Co-administration of Enzocort Oral Suspension 30 ml with Leflunomide may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Enzocort Oral Suspension 30 ml and Leflunomide, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Enzocort Oral Suspension 30 ml:
Using Aspirin together with Enzocort Oral Suspension 30 ml may increase the risk of gastric and intestinal ulcers, bleeding and perforation.

How to manage the interaction:
Co-administration of Aspirin with Enzocort Oral Suspension 30 ml can result in an interaction, but it can be taken if a doctor has advised it. If you have any symptoms unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without consulting a doctor.
DeflazacortBoceprevir
Severe
How does the drug interact with Enzocort Oral Suspension 30 ml:
Coadministration of Boceprevir with Enzocort Oral Suspension 30 ml can increase the levels of Enzocort Oral Suspension 30 ml in the body. This increases the risk of side effects.

How to manage the interaction:
Taking Boceprevir with Enzocort Oral Suspension 30 ml together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, chest pain, or tightness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Enzocort Oral Suspension 30 ml:
Taking Primidone with Enzocort Oral Suspension 30 ml may significantly reduce the blood levels of Enzocort Oral Suspension 30 ml, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Primidone and Enzocort Oral Suspension 30 ml together can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Enzocort Oral Suspension 30 ml:
Gatifloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Enzocort Oral Suspension 30 ml.

How to manage the interaction:
Although there is an interaction, Gatifloxacin can be taken with Enzocort Oral Suspension 30 ml if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Enzocort Oral Suspension 30 ml:
coadministration of Levofloxacin and Enzocort Oral Suspension 30 ml can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone).

How to manage the interaction:
Although there is an interaction, Levofloxacin can be taken with Enzocort Oral Suspension 30 ml if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

A patient needs to take extra care of their hygiene and stay away from places or people believed to be a cause of infection, as this drug affects the immune system. Therefore, proper care is necessary.

 

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS
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Alcohol

Caution

The effect of taking both alcohol and Enzocort Oral Suspension may lead to bleeding and ulcers in the stomach. A doctor's consultation is recommended.

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Pregnancy

Unsafe

Not recommended in pregnant females.Enzocort Oral Suspension crosses the placenta and doses equivalent to &gt;40 mg prednisolone daily increase the risk of fetal and neonatal damage.

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Breast Feeding

Caution

No adverse effect is reported yet it is advised to have doctors' consultation by breastfeeding mothers.

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Driving

Unsafe

A patient may experience muscle weakness/feeling tired. Do not drive and do not use tools or machines while using this drug.

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Liver

Caution

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Enzocort Oral Suspension can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Enzocort Oral Suspension.

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Kidney

Caution

Before using Enzocort Oral Suspension by a kidney patient it is recommended to have a doctors consultation. It may affect the kidney in a few cases.

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Children

Unsafe

Enzocort Oral Suspension is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Enzocort Oral Suspension.

Have a query?

FAQs

Enzocort Oral Suspension is used to treat Duchene muscular dystrophy. It may also be used to treat allergic and inflammatory disorders.

Not recommended in mild allergies. Enzocort Oral Suspension is recommended only after consulting a doctor, as it is a strong medicine that produces considerable side effects, and is used only in moderate to severe cases.

It is not recommended to stop by a patient himself/herself, especially by a patient undergoing organ transplantation as it may worsen the situation.

It is not recommended to be taken Enzocort Oral Suspension with alcohol as it may cause stomach bleeding.

No its is not recommended to be used in seasonal allergy or mild cases. Only on doctors consultation, Enzocort Oral Suspension may be used in extreme cases of seasonal allergy.

You should not use Enzocort Oral Suspension if you have taken live vaccines of mumps, measles, rubella (MMR), polio, rotavirus, yellow fever, typhoid, nasal flu (influenza), varicella (chickenpox), and zoster (shingles). Do not take Enzocort Oral Suspension if you have a compromised immune system, eye problems or weak bones.

Yes, Enzocort Oral Suspension is a steroid medication. It's a corticosteroid, also known as a glucocorticoid.

Enzocort Oral Suspension is less potent than Prednisone and is usually administered proportionately in higher doses.

No, Enzocort Oral Suspension is not a painkiller. It is a steroid medication.

Yes, it can be used to treat kidney stones.

Swallow it whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.

It may be unsafe for some to use. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.

Yes, it is safe to use Enzocort Oral Suspension if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.

Inadequate data available on the use of this drug in pregnant women to inform a drug-related risk. So, it should be used during pregnancy only if the benefit outweighs the risk to the fetus.

Common side effects of Enzocort Oral Suspension may include nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Enzocort Oral Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Store in a cool and dry place away from sunlight. Please keep it away from pets and children.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - ENZ0022

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