Apollo
logo

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:ENTACAPONE-200MG
prescription
Prescription Medicine
info
image icons

Entocom Tablet is used to treat Parkinson's disease. It contains Entacapone which works by inhibiting a chemical messenger that supports increasing the amount of dopamine in the body; thereby, it helps the brain to control body movements. In some cases, this medicine may cause side effects such as nausea, fatigue, vomiting, confusion, constipation, diarrhoea, and abdominal pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

Read more
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

ENTACAPONE-200MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Entocom Tablet

Entocom Tablet is a prescription medication used to treat patients with Parkinson's disease who are experiencing 'wearing-off' symptoms. It is prescribed alongside standard Parkinson's therapies to help prolong the effectiveness of those treatments and maintain steadier muscle control. This medication serves to reduce the sudden return of motor symptoms, such as muscle stiffness, tremors, and slow movement, between your regularly scheduled doses.

To achieve the best results, you must take Entocom Tablet consistently with each of your primary Parkinson's medication doses throughout the day. You can take this tablet with or without food, though maintaining a consistent routine is highly recommended. Incorporating regular, gentle physical therapy and keeping a structured daily routine can significantly support your physical mobility and overall treatment outcomes.

While taking Entocom Tablet , some people may experience mild side effects like a harmless change in urine colour or slight nausea. However, you must contact your doctor immediately if you experience severe or persistent diarrhoea, confusion, or unusual, severe muscle pain. These serious symptoms require prompt medical evaluation to ensure your safety throughout therapy.

Before starting Entocom Tablet , talk to your doctor if you have a history of liver damage, severe muscle disorders, or skin conditions. Do not take this if you have had a severe allergic reaction to this medication in the past, or if you have a history of neuroleptic malignant syndrome (a rare but serious reaction to certain medicines) or non-traumatic muscle breakdown. Your doctor will carefully review your medical history to ensure this is the right option for you.

This medication can interact with other substances, such as iron supplements and certain types of antidepressants, which can reduce its effectiveness or cause unwanted side effects. Avoid alcohol while taking Entocom Tablet , as it can significantly increase dizziness and drowsiness. If you are pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to discuss your specific risks and benefits.

Uses of Entocom Tablet

Your doctor may prescribe this medicine to treat several conditions, including:

  • Parkinson's disease 'wearing-off' symptoms: Entocom Tablet is used in combination with other primary Parkinson's medications to prevent the treatment from wearing off prematurely. It helps provide more consistent control over muscle movements, reducing the time spent experiencing stiffness, shaking, and slow movement.

Key Benefits

Entocom Tablet helps improve movement control in people with Parkinson's disease by maintaining more consistent levels of therapy throughout the day. Key benefits include:

  • Increases 'On' Time: By helping maintain stable treatment effects, Entocom Tablet increases the amount of time during the day when movement is better controlled, reducing periods of symptom recurrence.
  • Provides Smoother Motor Control: By reducing fluctuations in movement, Entocom Tablet helps minimise episodes of stiffness, slowness, and impaired mobility, supporting more consistent physical function.
  • Supports Daily Activities: By improving motor control, Entocom Tablet helps make everyday tasks such as walking, eating, writing, and other routine activities easier, promoting greater independence and quality of life.
Side effects of Entocom Tablet
  • Uncontrolled and involuntary movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Wear loose, breathable clothing.
  • Stay in cool, well-ventilated areas.
  • Avoid strenuous activities.
  • Use fans or air conditioners.
  • Take cool showers or baths.
  • Use antiperspirants or deodorants.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Entocom Tablet can be taken with food or as directed by your doctor.
  • It is best advised to take Entocom Tablet at the same time each day to get effective results.
  • Swallow the tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

How Entocom Tablet Works

In people with Parkinson's disease, the brain lacks a chemical messenger called dopamine. Primary medications like levodopa are converted into dopamine in the brain to help control movement. However, certain enzymes in the body naturally break down levodopa before it can ever reach the brain, reducing its effectiveness over time. Entocom Tablet contains entacapone, which works by blocking one of these key enzymes, known as COMT. By temporarily turning off this enzyme, Entocom Tablet allows more of your primary Parkinson's medication to enter the brain where it is needed. This ensures a steadier, longer-lasting supply of dopamine, which keeps your movements smoother and prevents sudden, frustrating 'off' episodes.
bannner image

Alcohol

Unsafe

Taking the drug along with alcohol may increase the side effects such as confusion, drowsiness and trouble in concentration.

bannner image

Pregnancy

Caution

Entocom Tablet is generally not recommended for use in pregnancy. If you are pregnant, please consult your doctor before taking this medicine. Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

No clinical use of Entocom Tablet during breastfeeding has been reported. The drug might reduce serum prolactin and may affect milk production. If you are breastfeeding, consult your doctor before taking Entocom Tablet .

bannner image

Driving

Caution

Entocom Tablet may cause low blood pressure that further cause drowsiness and dizziness. So, it is not recommended to drive or operate heavy machinery after taking Entocom Tablet .

bannner image

Liver

Caution

Entocom Tablet should be used with caution in patients with liver disease. If you have liver problems, your doctor may adjust the dose of Entocom Tablet or prescribe a suitable alternative based on your condition.

bannner image

Kidney

Caution

Entocom Tablet should be used with caution in patients with kidney disease. If you have kidney problems, your doctor may adjust the dose of Entocom Tablet or prescribe a suitable alternative based on your condition.

bannner image

Children

Caution

Entocom Tablet is not recommended for use in children under 18 years as the safety and effectiveness were not established. Consult a child specialist for further information.

bannner image

Heart

Safe if prescribed

Entocom Tablet is safe for use in heart patients if prescribed by the physician.

bannner image

Geriatrics

Safe if prescribed

Entocom Tablet is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Entocom Tablet

In case of an accidental overdose, seek immediate emergency medical attention or contact your local poison control centre right away.

Diet & Lifestyle Advise

  • Protein timing: Large amounts of dietary protein can compete with your companion Parkinson's medications for absorption. Talk to your doctor or a dietitian about how to space out high-protein foods throughout the day.
  • Stay hydrated: Drink plenty of water throughout the day to help manage common issues like dry mouth and to support healthy bowel movements.
  • Avoid alcohol: Consuming alcohol while taking this medicine can worsen dizziness and make you feel extremely drowsy, increasing the risk of falls.
  • Space iron supplements: If you take iron pills, make sure to take them at least 2 to 3 hours before or after taking Entocom Tablet , as iron can bind to the medication and stop your body from absorbing it properly.
health query

Have a query?

How Soon It Starts Working

The time required for Entocom Tablet to start to work: The time required for Entocom Tablet to show its action is unknown. The time for which the effects of Entocom Tablet last: The duration of action for Entocom Tablet is unknown.

What if you forget to take Entocom Tablet

If you miss a dose, take it as soon as you remember, provided you are also taking your companion Parkinson's medication. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure.

Storage

• Store Entocom Tablet tablets at controlled room temperature, specifically between 20°C and 25°C (68°F and 77°F• Keep the medication in its original container, tightly closed, to protect it from moisture and direct light.

Drug Warnings

  • Expect urine colour changes: Do not be alarmed if your urine turns reddish-brown or orange while taking Entocom Tablet . This is a harmless and expected effect of the medicine.
  • Stand up slowly: Rise gradually from a sitting or lying position, as this medicine may cause a sudden drop in blood pressure, leading to dizziness, light-headedness, or falls.
  • Do not stop treatment suddenly: Never discontinue Entocom Tablet without consulting your doctor. Stopping the medicine abruptly may cause a serious reaction with high fever, severe muscle stiffness, confusion, and changes in consciousness.
  • Use caution with activities requiring alertness: This medicine may cause severe drowsiness or sudden episodes of falling asleep. Avoid driving, operating machinery, or performing hazardous tasks until you know how it affects you.
  • Report severe diarrhoea promptly: If you develop persistent or severe diarrhoea, stop taking the medicine and contact your healthcare provider immediately, as prolonged diarrhoea can lead to dehydration and electrolyte imbalance.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Non-selective MAO inhibitors: Combining this medicine with certain antidepressants (such as phenelzine or tranylcypromine) can cause dangerously high blood pressure.
  • Iron supplements: Taking iron pills or multivitamins containing iron at the same time can greatly reduce the absorption and effectiveness of Entocom Tablet .
  • COMT-metabolized drugs: It may increase the effects of medications like epinephrine, norepinephrine, or dobutamine, which can affect your heart rate and blood pressure.
EntacaponeTranylcypromine
Critical
EntacaponePhenelzine
Critical

Drug-Drug Interactions

Login/Sign Up

EntacaponeTranylcypromine
Critical
How does the drug interact with Entocom Tablet:
Coadministration of Entocom Tablet with Tranylcypromine can increase the risk of high blood pressure and also increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Entocom Tablet with Tranylcypromine can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
EntacaponePhenelzine
Critical
How does the drug interact with Entocom Tablet:
Combining Entocom Tablet with Phenelzine can increase the risk of serious condition called the serotonin syndrome.

How to manage the interaction:
Taking Entocom Tablet with Phenelzine is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
EntacaponeIsocarboxazid
Critical
How does the drug interact with Entocom Tablet:
Combining Entocom Tablet with Isocarboxazid can increase the risk of serious condition called the serotonin syndrome.

How to manage the interaction:
Taking Entocom Tablet with Isocarboxazid is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, if you experience sudden extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, Contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EntacaponeLinezolid
Critical
How does the drug interact with Entocom Tablet:
Coadministration of Entocom Tablet with Linezolid might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Entocom Tablet with Linezolid is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EntacaponeEsketamine
Severe
How does the drug interact with Entocom Tablet:
Combining Entocom Tablet with Esketamine can increase the risk and severity of side effects (drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination).

How to manage the interaction:
Although taking Entocom Tablet and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms like feeling sleepy, having trouble concentrating, or feeling confused, it's important to let a doctor know right away. Do not stop using any medications without talking to a doctor.
EntacaponeFurazolidone
Severe
How does the drug interact with Entocom Tablet:
Combining Entocom Tablet with Furazolidone can increase the risk of CNS depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is a possible interaction between Entocom Tablet and Furazolidone, you can take these medicines together if prescribed by your doctor. It's important to keep an eye on your health. If you notice any of these signs - very high blood pressure, feeling really unwell, confusion, seeing or hearing things that aren't there, having a seizure, a faster heartbeat, fever, sweating a lot, shivering or shaking, trouble seeing clearly, muscle spasms or stiffness, difficulty moving, stomach cramps, feeling sick, throwing up, or having diarrhea - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
EntacaponeProcarbazine
Severe
How does the drug interact with Entocom Tablet:
Combining Entocom Tablet with Procarbazine can increase the risk or severity of side effects like decreased rate of breathing, decreased heart rate, and loss of consciousness.

How to manage the interaction:
Although taking Entocom Tablet and Procarbazine together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms like confusion, hallucinations, seizures, fast heartbeat, fever, sweating, shivering, blurred vision, muscle spasms, stiffness, trouble moving, cramps, feeling sick, throwing up, or having diarrhea - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
EntacaponeMethylene blue
Severe
How does the drug interact with Entocom Tablet:
Combining Entocom Tablet with Methylene blue can increase the risk of CNS depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Entocom Tablet with Methylene blue together can result in an interaction, but it can be taken if your doctor has advised it. It's important to keep an eye on your health. If you notice any of these signs - very high blood pressure, feeling confused or hallucinating, having a seizure, a fast heartbeat, fever, sweating a lot, shivering or shaking, trouble seeing clearly, muscle spasms or stiffness, difficulty coordinating movements, stomach cramps, feeling sick, throwing up, or having diarrhea - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
EntacaponeSodium oxybate
Severe
How does the drug interact with Entocom Tablet:
Taking Entocom Tablet with Sodium oxybate can increase the risk or severity of side effects like decreased rate of breathing, decreased heart rate, and loss of consciousness.

How to manage the interaction:
Although taking Entocom Tablet and Sodium oxybate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms like fatigue, dizziness, lightheaded, drowsiness, confusion, shortness of breath, chest pain or tightness, make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • High-protein meals: Eating meals exceptionally high in protein at the same time you take your medication can interfere with how well your body absorbs your companion Parkinson's treatment, making it less effective.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPARKINSON AGENTS]

FAQs

This is a completely harmless side effect. The medication has a natural color that passes through your kidneys and is excreted in your urine. It does not mean there is blood in your urine, but it can stain clothing. Talk to your doctor if you have concerns.
Yes. Entocom Tablet , especially when taken together with levodopa, can cause significant daytime drowsiness and, in some people, sudden episodes of falling asleep during normal activities such as driving, eating, or talking. Do not drive or operate machinery until you know how this medicine affects you. Contact your doctor if you experience excessive sleepiness or sudden sleep episodes.
No, Entocom Tablet does not work on its own. It is designed specifically to assist other Parkinson's medications, like levodopa, by preventing them from breaking down too quickly in your body. It must always be taken together with your companion Parkinson's treatment. Talk to your doctor for more details.
You can take Entocom Tablet either with or without food. The most important thing is to be consistent with how you take it each day and to make sure you take it at the exact same time as your companion Parkinson's medication. Talk to your doctor or pharmacist if you need help planning your schedule.
Severe, persistent diarrhea is a recognized side effect that can occur even after weeks or months of taking this medicine. If you experience this, contact your doctor right away, as it can cause serious dehydration, and your doctor may advise you to stop taking the medication.
Iron can bind to Entocom Tablet in your stomach, which prevents your body from absorbing the medicine. If you must take iron supplements or multivitamins containing iron, take them at least 2 to 3 hours before or after you take your medication. Talk to your doctor or pharmacist to help schedule your doses safely.
Because Entocom Tablet is absorbed quickly, it begins working alongside your primary Parkinson's medication with your very first doses. You should notice a reduction in your "wearing-off" symptoms and more consistent movement control within a few days. Talk to your doctor if you do not notice any improvement.
No, you should never stop taking this medication suddenly. Doing so can cause a severe, dangerous reaction characterised by high fever, muscle rigidity, and rapid changes in blood pressure. If you need to stop or change your treatment, your doctor will guide you on how to do so safely. Talk to your doctor before making any changes.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ENT0035

Buy best C.n.s Drugs products by

whatsapp Floating Button
Buy Now
Add to Cart