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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dutalosin Tablet is used to treat an enlarged prostate gland. It contains Tamsulosin hydrochloride and Dutasteride, which relaxes the muscles of the prostate gland and relieves the symptoms of urinary incontinence. This medicine may cause common side effects such as dizziness, lightheadedness, drowsiness, sexual problems (decreased sex drive or libido), runny/stuffy nose, reduced amount of semen/sperm, testicle pain/swelling, increased breast size or breast tenderness. Let your doctor know if you are taking any other medicines or have pre-existing medical conditions.

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Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dutalosin Tablet

Dutalosin Tablet is used to treat the symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate. Benign prostatic hyperplasia is a non-cancerous growth of the prostate gland caused by the overproduction of a hormone called dihydrotestosterone in men.

Dutalosin Tablet contains Tamsulosin hydrochloride and Dutasteride. Dutasteride shrinks the enlarged prostate, and Tamsulosin hydrochloride relaxes muscles in the prostate and neck of the bladder. Thereby, Dutalosin Tablet treats enlarged prostate.

The most common side effects of Dutalosin Tablet are dizziness, lightheadedness, drowsiness, decreased sex drive or libido, runny/stuffy nose, reduced amount of semen/sperm, testicle pain/swelling, and increased breast size or breast tenderness. If any of these side effects persist or worsen, tell your doctor promptly.

Do not take Dutalosin Tablet if you are allergic to any of its components. Women or children should not take Dutalosin Tablet . Keep your doctor informed about your health condition and medications to prevent any potential interactions.

Uses of Dutalosin Tablet

Dutalosin Tablet is used in the treatment of Benign prostatic hyperplasia (BPH). The detailed uses of Dutalosin Tablet are as follows:

  • Management of benign prostatic hyperplasia (BPH): Dutalosin Tablet helps to manage symptoms of enlarged prostate (BPH), like difficulty urinating, and improves quality of life.
  • Acute urinary retention: Dutalosin Tablet treats acute urinary retention by relaxing prostate muscles and shrinking the prostate gland, thereby improving urine flow.
  • Management of urinary symptoms: Dutalosin Tablet helps to relieve symptoms like frequent urination, urgency, weak urine flow, and incomplete bladder emptying.
  • Support for bladder function: Dutalosin Tablet supports bladder function, particularly in patients with benign prostatic hyperplasia (BPH), by relaxing bladder muscles, improving urinary tract health.

Directions for Use

  • Dutalosin Tablet should be taken 30 minutes after a meal.
  • It is usually taken once daily at the same time each day or as prescribed by your doctor.
  • Swallow Dutalosin Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

Medicinal Benefits

  • Dutalosin Tablet is a combination medication used to treat Benign Prostatic Hyperplasia (BPH), a non-cancerous enlargement of the prostate gland in men.
  • It helps improve symptoms such as difficulty in starting urination, weak urine stream, frequent or urgent need to urinate (especially at night), and incomplete bladder emptying.
  • Dutasteride, a 5-alpha reductase inhibitor, lowers levels of dihydrotestosterone (DHT), a hormone responsible for prostate growth. This leads to a gradual shrinkage of the enlarged prostate, relieving pressure on the urinary tract.
  • Tamsulosin hydrochloride, an alpha-blocker, relaxes the muscles in the prostate and bladder neck, making it easier to pass urine and reducing urinary obstruction.
  • Dutalosin Tablet reduces the risk of acute urinary retention (sudden inability to urinate) and lowers the likelihood of needing prostate surgery.
  • The combination of two different mechanisms provides more effective and sustained symptom relief compared to either drug used alone.
  • Overall, Dutalosin Tablet significantly improves urinary flow and quality of life in men with BPH and helps slow the progression of the disease.

How Dutalosin Tablet Works

Dutalosin Tablet contains Tamsulosin hydrochloride (alpha-blockers) and Dutasteride (5-alpha reductase inhibitor). Tamsulosin makes it easy to pass urine by relaxing the muscles of the prostate gland. On the other hand, Dutasteride reduces the size of the enlarged prostate gland by lowering the production of dihydrotestosterone hormone, thereby relieving the symptoms of urinary incontinence. Together, Dutalosin Tablet helps treat benign prostatic hyperplasia.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Dutalosin Tablet

Do not take more than the prescribed dose of Dutalosin Tablet as it may cause an overdose leading to unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Dutalosin Tablet if you are allergic to any of its components.
  • Inform your doctor if you have liver or kidney problems, low blood pressure, or if you are planning to undergo cataract or glaucoma surgery.
  • Pregnant women should not handle Dutalosin Tablet , especially if they are leaking or broken. If a pregnant woman absorbs the active ingredient, either by touching or swallowing the medication, the male baby may be born with sex organs that are not normal. If contact occurs, the affected area should be washed immediately with soap and water.
  • Avoid donating blood during treatment with Dutalosin Tablet and for 6 months after the last dose.
  • Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Drug-Drug Interactions

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TamsulosinIdelalisib
Severe

Drug-Drug Interactions

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How does the drug interact with Dutalosin Tablet:
Taking Dutalosin Tablet with posaconazole may significantly increase the blood levels and effects of Dutalosin Tablet.

How to manage the interaction:
Although taking Dutalosin Tablet and posaconazole together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience dizziness, lightheadedness, fainting, headache, and stuffy nose. Do not stop using any medications without consulting a doctor.
TamsulosinIdelalisib
Severe
How does the drug interact with Dutalosin Tablet:
Taking Dutalosin Tablet with idealisib may significantly increase the blood levels and effects of Dutalosin Tablet.

How to manage the interaction:
Although taking Dutalosin Tablet and idealisib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection unrelated to sexual activity). Do not stop using any medications without consulting doctor.
TamsulosinAmprenavir
Severe
How does the drug interact with Dutalosin Tablet:
Taking Dutalosin Tablet with amprenavir may significantly increase the blood levels and effects of Dutalosin Tablet.

How to manage the interaction:
Although taking Dutalosin Tablet and amprenavir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection unrelated to sexual activity). Do not stop using any medications without consulting doctor.
TamsulosinTelithromycin
Severe
How does the drug interact with Dutalosin Tablet:
Taking Dutalosin Tablet with telithromycin may significantly increase the blood levels and effects of Dutalosin Tablet.

How to manage the interaction:
Although taking Dutalosin Tablet and telithromycin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection unrelated to sexual activity). Do not stop using any medications without consulting doctor.
How does the drug interact with Dutalosin Tablet:
Taking Dutalosin Tablet with Voriconazole may significantly increase the blood levels and effects of Dutalosin Tablet.

How to manage the interaction:
Although taking Dutalosin Tablet and Voriconazole together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience dizziness, heart palpitation (irregular heartbeat). Do not stop using any medications without consulting doctor.
How does the drug interact with Dutalosin Tablet:
Dutalosin Tablet blood levels may rise when itraconazole and Dutalosin Tablet are administered together.

How to manage the interaction:
Itraconazole and Dutalosin Tablet may interact, but if a doctor prescribes them, you can still take them. If you develop dizziness, lightheadedness, fainting, headache, redness, nasal congestion, a racing heart, or priapism (prolonged and painful erection unrelated to sex), you should consult a doctor. Never stop taking any medication without consulting a doctor.
How does the drug interact with Dutalosin Tablet:
Taking Dutalosin Tablet with atazanavir may significantly increase the blood levels and effects of Dutalosin Tablet.

How to manage the interaction:
Although taking Dutalosin Tablet and atazanavir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection unrelated to sexual activity). Do not stop using any medications without consulting doctor.
TamsulosinFosamprenavir
Severe
How does the drug interact with Dutalosin Tablet:
Taking Dutalosin Tablet with fosamprenavir may significantly increase the blood levels and effects of Dutalosin Tablet.

How to manage the interaction:
Although taking Dutalosin Tablet and fosamprenavir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection unrelated to sexual activity). Do not stop using any medications without consulting doctor.
How does the drug interact with Dutalosin Tablet:
Taking clarithromycin with Dutalosin Tablet may increase the blood levels and effects of Dutalosin Tablet.

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Dutalosin Tablet if prescribed by the doctor. Consult the prescriber if you experience side effects such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection unrelated to sexual activity). Do not stop using any medications without a doctor's advice.
How does the drug interact with Dutalosin Tablet:
Taking Dutalosin Tablet with Tizanidine will have an additive effect and may lower blood pressure.

How to manage the interaction:
Although taking Dutalosin Tablet and tizanidine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Use caution when getting up from a sitting or lying position. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid drinking alcohol, caffeine and fizzy drinks. Limit intake of artificial sweeteners.
  • Maintain a healthy lifestyle and exercise regularly to avoid abdominal discomfort.
  • Also, drink less water in the evening and before sleeping so that you can have a sound sleep and do not wake up frequently for urination.
  • Any medication which may worsen urinary symptoms (medicines for cold and cough) should be avoided.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Dutalosin Tablet . Please consult your doctor.

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Pregnancy

Unsafe

Dutalosin Tablet is intended for use in men. It is not recommended for use in women. Pregnant women should not handle Dutalosin Tablet due to the potential risk to the male fetus.

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Breast Feeding

Unsafe

Dutalosin Tablet is intended for use in men. It is not recommended for use in women.

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Driving

Caution

Dutalosin Tablet can make some people feel dizzy, so it may affect your ability to drive or operate machinery safely.

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Liver

Consult your doctor

The effect of Dutalosin Tablet in patients with liver impairment has not been studied. Please consult your doctor if you have liver problems.

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Kidney

Consult your doctor

The effect of Dutalosin Tablet in patients with kidney impairment has not been studied. Please consult your doctor if you have kidney problems.

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Children

Unsafe

Dutalosin Tablet is not recommended for children. The safety and effectiveness of Dutalosin Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

Have a query?

FAQs

Dutalosin Tablet is used to treat symptoms of benign prostatic hyperplasia (enlarged prostate gland).

Dutalosin Tablet contains Dutasteride and Tamsulosin hydrochloride. Tamsulosin hydrochloride makes it easy to pass urine by relaxing the prostate gland muscles. On the other hand, Dutasteride reduces the size of the enlarged prostate gland by lowering the production of dihydrotestosterone hormone, thereby relieving the symptoms of urinary incontinence that minimises the need for prostate surgery and the risk of acute urinary retention.

No, Dutalosin Tablet does not cure urinary bladder cancer. It just helps in relieving symptoms of the enlarged prostate gland. For better advice, you should consult your doctor.

No, you are advised not to donate blood if you are taking Dutalosin Tablet . Even if you stop taking Dutalosin Tablet , wait for at least 6 months and consult your doctor before donating blood.

No, taking any cold or cough medication along with Dutalosin Tablet should be avoided as it increases the urge to urinate. So, before taking any such medication, please consult your doctor.

The expiration date of any drug is the last day the manufacturer guarantees the drug's full potency. Discuss with your doctor, Dutalosin Tablet can be taken 15-20 days after the expiry date, given the shape, colour, and state of the tablet has not changed. If you find any slight change in the form of medicine, please do not consume it.

Yes, in some cases, sexual problems (like decreased sexual interest/ability/libido, ejaculation problems, decreased sperm/semen amount), testis pain/swelling, increased breast size or breast tenderness in the male might occur. Sexual problems in a male may continue even after stopping the intake of Dutalosin Tablet . However, if any of these side effects persist, tell your doctor promptly.

Dutalosin Tablet is known to be harmful to men below the age of 18, childbearing women, and patients with known allergies to any of the components of Dutalosin Tablet .

Dutalosin Tablet should be used with caution and only if prescribed by the doctor in the elderly. Please consult the doctor if you have any concerns.

Dutalosin Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Yes, Dutalosin Tablet is effective if taken as advised by the doctor for the prescribed duration.

Yes, Dutalosin Tablet may cause dizziness in some people. Do not drive or operate machinery if you experience dizziness. Avoid getting up too fast from a sitting or lying position as doing so may cause lightheadedness; instead, lie down and get up only when you feel better.

Let the doctor know if you have liver problems or if you are due to undergo cataract surgery. Women and children should not handle Dutalosin Tablet if they are leaking, as it can be absorbed through the skin. It is advised to use a condom during sexual intercourse during treatment with Dutalosin Tablet . Avoid donating blood while taking Dutalosin Tablet and for at least 6 months after your last dose.

Yes, Dutalosin Tablet is usually a safe and well-tolerated medicine if taken as advised by the doctor.

No, do not take a higher dose than the recommended dose of Dutalosin Tablet , as it might cause an overdose. Take Dutalosin Tablet only according to the dose and duration prescribed by the doctor.

Store Dutalosin Tablet at room temperature, protected from light and moisture. Do not freeze. Keep it out of sight and reach of children.

Yes, Dutalosin Tablet may cause ejaculation problems, such as difficulty ejaculating or a decrease in the amount of semen released during sex. Please talk to the doctor if you have any concerns regarding this.

Yes, Dutalosin Tablet may cause priapism (persistent painful erection of the penis). However, it is a very rare side effect of Dutalosin Tablet which may not be experienced by everyone taking Dutalosin Tablet . Consult the doctor if you experience a painful erection that lasts for more than 4 hours.

No, Dutalosin Tablet should not be used if you are due to undergo cataract surgery. Your doctor may ask you to stop taking Dutalosin Tablet for a while before your operation to prevent complications during the surgery.

Limit fizzy drinks, alcohol, caffeine and artificial sweeteners, drink less fluid in the evening, remember to empty your bladder whenever you have the urge to pee, and include fibre-rich food in your diet.

The most common side effects of Dutalosin Tablet are dizziness, lightheadedness, drowsiness, sexual problems (decreased sex drive or libido), runny/stuffy nose, reduced amount of semen/sperm), testicle pain/swelling, increased breast size or breast tenderness. If any of these side effects persist or worsen, tell your doctor promptly.

Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - DUT0072

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