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  1. Home
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  3. Dubfree Tablet

Prescription drug
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Dubfree Tablet, Pack of 1 Tablet
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dubfree Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

NORETHISTERONE-5MG

Manufacturer/Marketer :

Goodman Gilman's Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dubfree Tablet

Dubfree Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Endometriosis is a disorder in which the uterus's tissue lining (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis.

Dubfree Tablet contains Norethisterone, which mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining.

Common side effects include unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhoea, headache, breast pain, and tenderness. Most of these side effects do not require medical attention. However, if the side effects persist, please consult your doctor.

If you are allergic to Dubfree Tablet or any other medicines, please tell your doctor. Dubfree Tablet is not recommended for pregnant women as it may harm the unborn baby. If you are breastfeeding, consult a doctor before taking Dubfree Tablet. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Dubfree Tablet.

Uses of Dubfree Tablet

Dubfree Tablet is used to treat endometriosis. The detailed uses of Dubfree Tablet are as follows:

  • Menstrual Cycle Regulation: Dubfree Tablet is commonly used to regulate irregular menstrual cycles or to induce menstruation in women experiencing amenorrhea (absence of periods).
  • Management of Endometriosis: Dubfree Tablet is also effective in managing endometriosis, a condition where uterine-like tissue grows outside the uterus, leading to pain and irregular bleeding.
  • Support in Hormone Replacement Therapy: In postmenopausal women, Dubfree Tablet is often combined with estrogen therapy to prevent endometrial hyperplasia (thickening of the uterine lining), which can result from estrogen use alone.
  • Relieve Menstrual problems: Dubfree Tablet is sometimes prescribed to alleviate symptoms of premenstrual syndrome (PMS) and to provide relief from excessive bleeding or pain during menstruation.

Have a query?

Directions for Use

  • Dubfree Tablet can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Dubfree Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • Dubfree Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone.
  • It restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps treat menstrual disorders.
  • Dubfree Tablet is also used in the treatment of breast cancer.

How Dubfree Tablet Works

Dubfree Tablet contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Storage

• Store in a cool and dry place away from sunlight.• Keep Dubfree Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Dubfree Tablet

Take Dubfree Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, breast enlargement and vaginal bleeding. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are allergic to Dubfree Tablet or any other medicines, please tell your doctor.
  • Dubfree Tablet is not recommended for pregnant women as it may harm an unborn baby.
  • If you are breastfeeding, consult a doctor before taking Dubfree Tablet.
  • It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Dubfree Tablet.
  • You are advised to stop smoking while taking Dubfree Tablet as it may increase the risk of adverse effects.
  • If you are about to undergo any surgery, please inform your doctor that you are taking Dubfree Tablet as it may increase the effect of certain anesthetics.
  • If you experience sudden shortness of breath, rapid heartbeat, sudden, severe, sharp pain in the chest, or cough up blood, stop taking Dubfree Tablet and consult a doctor immediately as these might be signs of a blood clot in the lungs.

Drug-Drug Interactions

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NorethisteronePrimidone
Severe
NorethisteroneRifabutin
Severe

Drug-Drug Interactions

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NorethisteronePrimidone
Severe
How does the drug interact with Dubfree Tablet:
Coadministration of Dubfree Tablet and primidone can reduce the blood levels and effects of Dubfree Tablet and increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Dubfree Tablet and Primidone, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneRifabutin
Severe
How does the drug interact with Dubfree Tablet:
Coadministration of Dubfree Tablet with Rifabutin can reduce the blood levels and effects of norethindrone.This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Dubfree Tablet with Rifabutin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneFosamprenavir
Severe
How does the drug interact with Dubfree Tablet:
Using norethindrone together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Taking Dubfree Tablet with Fosamprenavir together can result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing any symptoms, it's important to reach out to a doctor right away. They can recommend other options that won't interfere with your medication. Do not discontinue any medications without consulting a doctor.
NorethisteroneCarbamazepine
Severe
How does the drug interact with Dubfree Tablet:
Taking carbamazepine and Dubfree Tablet may possibly reduce the effects of Dubfree Tablet which may result in higher risk of breakthrough bleeding and unexpected pregnancy.

How to manage the interaction:
Although taking carbamazepine and Dubfree Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Contact your doctor if you experience hot flashes, vaginal dryness, or uncontrolled bleeding. Do not discontinue any medications without consulting a doctor.
NorethisteroneRifapentine
Severe
How does the drug interact with Dubfree Tablet:
Combining Rifapentine and norethindrone reduces the blood levels and effects of norethindrone and increases the risk of bleeding and unintended pregnancy.

How to manage the interaction:
Although there is a possible interaction between Dubfree Tablet and Rifapentine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like unexpected bleeding, abnormal bleeding, it's important to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
NorethisteroneBosentan
Severe
How does the drug interact with Dubfree Tablet:
Co-administration of Dubfree Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Dubfree Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
NorethisteroneBexarotene
Severe
How does the drug interact with Dubfree Tablet:
Coadministration of Bexarotene and Dubfree Tablet together can decrease the effectiveness of norethindrone and increase the risk of unintended pregnancy.

How to manage the interaction:
Combining Bexarotene with Dubfree Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneMycophenolic acid
Severe
How does the drug interact with Dubfree Tablet:
Coadministration of Dubfree Tablet and Mycophenolic acid can decrease the levels and effects of Dubfree Tablet.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Dubfree Tablet, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
NorethisteroneRifampicin
Severe
How does the drug interact with Dubfree Tablet:
Taking Dubfree Tablet with rifampicin can decrease the blood levels of Dubfree Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Dubfree Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteronePhenytoin
Severe
How does the drug interact with Dubfree Tablet:
Coadministration of Phenytoin and Dubfree Tablet may decrease the blood levels of Dubfree Tablet, which may make Dubfree Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Dubfree Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Dubfree Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Dubfree Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Dubfree Tablet dose.

Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

PROGESTIN

All Substitutes & Brand Comparisons

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Alcohol

Consult your doctor

The interaction of Dubfree Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Dubfree Tablet.

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Pregnancy

Unsafe

Dubfree Tablet is a category X pregnancy drug and is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Dubfree Tablet is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Dubfree Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

Dubfree Tablet is not recommended if you have liver disease. However, if you have any concerns regarding this, please consult a doctor.

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Kidney

Caution

Take Dubfree Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Dubfree Tablet is not recommended for use in children under 18 years.

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Heart

Dubfree Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Dubfree Tablet.

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Geriatrics

Unsafe

Dubfree Tablet is generally not recommended for elderly patients due to an increased risk of side effects and reduced effectiveness.

FAQs

Dubfree Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Dubfree Tablet may be used in the treatment of breast cancer.

Dubfree Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Dubfree Tablet may be used to delay periods. Dubfree Tablet keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Dubfree Tablet.

Dubfree Tablet may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoke, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Dubfree Tablet.

You are not recommended to take Dubfree Tablet with rifampicin as it may decrease the levels of Dubfree Tablet in blood and reduce its effectiveness. However, please consult a doctor before taking Dubfree Tablet with other medicines.

Country of origin

India

Manufacturer/Marketer address

Flat No. 608. 6Th Floor, Kirti Shikhar Building Distt. Centre, Janak Puri New Delhi Dl 110058 Indi
Other Info - DU40082

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 18, 2025 | 7:28 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.1494.pdf
  2. https://www.drugs.com/mtm/norethindrone.html
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