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Composition :

PIROXICAM-20MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Dolonex IM 20 mg Injection 1 ml

Dolonex IM 20 mg Injection 1 ml is used to relieve symptoms like pain and inflammation associated with rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage).

Dolonex IM 20 mg Injection 1 ml contains Piroxicam, which works by blocking the action of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes, which make another chemical, prostaglandins.

In some cases, you may experience certain common side effects such as injection site reactions, diarrhoea, dizziness, nausea, vomiting, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time.

Consult your doctor before taking Dolonex IM 20 mg Injection 1 ml if you are pregnant or breastfeeding. Dolonex IM 20 mg Injection 1 ml is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Dolonex IM 20 mg Injection 1 ml as it could lead to increased drowsiness and dizziness.

Uses of Dolonex IM 20 mg Injection 1 ml

Dolonex IM 20 mg Injection 1 ml is used in the treatment of Musculoskeletal pain, Osteoarthritis, and Rheumatoid arthritis. The detailed uses of Dolonex IM 20 mg Injection 1 ml are as follows:

  • Rheumatoid Arthritis: Dolonex IM 20 mg Injection 1 ml is used to reduce inflammation and pain associated with rheumatoid arthritis, helping to slow disease progression.
  • Osteoarthritis: Dolonex IM 20 mg Injection 1 ml manages osteoarthritis by alleviating joint pain, stiffness, and swelling, improving joint function and mobility.
  • Musculoskeletal Disorders: Dolonex IM 20 mg Injection 1 ml relieves pain and inflammation in musculoskeletal conditions, such as strains and sprains, improving overall mobility.

Have a query?

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Dolonex IM 20 mg Injection 1 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

Medicinal Benefits

  • Dolonex IM 20 mg Injection 1 ml belongs to the group of pain killers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to treat musculoskeletal pain.
  • It is also used to relieve symptoms associated with osteoarthritis, and rheumatoid arthritis, such as stiffness, swelling, and joint pain.
  • Dolonex IM 20 mg Injection 1 ml works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins.
  • Prostaglandins are produced at the injury site and cause pain and swelling.
  • By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

How Dolonex IM 20 mg Injection 1 ml Works

Dolonex IM 20 mg Injection 1 ml contains 'Piroxicam' that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at the injury site and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

• Store in a cool and dry place away from sunlight.• Keep Dolonex IM 20 mg Injection 1 ml out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Dolonex IM 20 mg Injection 1 ml

A healthcare professional administers Dolonex IM 20 mg Injection 1 ml as prescribed. Hence, the chances of overdose are less. Overdose may cause a lack of energy, drowsiness, upset stomach, vomiting, stomach pain, bloody, black, or tarry stools, vomiting a substance that is bloody or looks like coffee grounds, and difficulty breathing. Your doctor may initiate the necessary treatment if an overdose is suspected.

Drug Warnings

  • Dolonex IM 20 mg Injection 1 ml may increase the risk of serious heart-related problems, like heart attack and stroke. So, if you are a heart patient, let your doctor know before taking Dolonex IM 20 mg Injection 1 ml.
  • Besides this, Dolonex IM 20 mg Injection 1 ml may also cause stomach and intestinal bleeding/ulcers, so let your doctor know if you have these problems.
  • Do not take Dolonex IM 20 mg Injection 1 ml if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG) as it can increase the risk of a heart attack.
  • Consult your doctor before taking Dolonex IM 20 mg Injection 1 ml if you are pregnant or breastfeeding.
  • Dolonex IM 20 mg Injection 1 ml may cause dizziness, so drive only if you are alert.
  • Dolonex IM 20 mg Injection 1 ml is not recommended for children as safety has not been established.
  • Avoid consuming alcohol along with Dolonex IM 20 mg Injection 1 ml as it could lead to increased dizziness and may increase the risk of stomach bleeding.
  • Inform your doctor before taking Dolonex IM 20 mg Injection 1 ml if you have asthma, water retention (oedema) or high blood pressure, a stuffy/runny nose, nasal polyps, liver or kidney problems.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dolonex IM 20 mg Injection 1 ml:
Using ketorolac tromethamine together with Dolonex IM 20 mg Injection 1 ml may increase the risk of side effects.

How to manage the interaction:
Taking Dolonex IM 20 mg Injection 1 ml with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dolonex IM 20 mg Injection 1 ml:
Co-administration of Cidofovir with Dolonex IM 20 mg Injection 1 ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Dolonex IM 20 mg Injection 1 ml with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamDanaparoid
Severe
How does the drug interact with Dolonex IM 20 mg Injection 1 ml:
Coadministration of Dolonex IM 20 mg Injection 1 ml with Danaparoid can increase the risk of bleeding.

How to manage the interaction:
Although taking Dolonex IM 20 mg Injection 1 ml and Danaparoid together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dolonex IM 20 mg Injection 1 ml:
Coadministration of Dolonex IM 20 mg Injection 1 ml and Rivaroxaban can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Dolonex IM 20 mg Injection 1 ml and Rivaroxaban can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dolonex IM 20 mg Injection 1 ml:
Taking tacrolimus with Dolonex IM 20 mg Injection 1 ml may increase risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Dolonex IM 20 mg Injection 1 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dolonex IM 20 mg Injection 1 ml:
Using perindopril together with Dolonex IM 20 mg Injection 1 ml may reduce the effects of perindopril in lowering blood pressure, they may also increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Dolonex IM 20 mg Injection 1 ml with Perindopril can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, and irregular heart rhythm, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dolonex IM 20 mg Injection 1 ml:
Coadministration of Nabumetone with Dolonex IM 20 mg Injection 1 ml can increase the risk of side effects inflammation(swelling with redness and pain), bleeding, ulceration, and perforation.

How to manage the interaction:
Co-administration of Dolonex IM 20 mg Injection 1 ml with Nabumetone can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamSulindac
Severe
How does the drug interact with Dolonex IM 20 mg Injection 1 ml:
Using Dolonex IM 20 mg Injection 1 ml together with sulindac may increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Co-administration of Dolonex IM 20 mg Injection 1 ml with Sulindac can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dolonex IM 20 mg Injection 1 ml:
Coadministration of Dolonex IM 20 mg Injection 1 ml and Teriflunomide can increase the risk of liver damage.

How to manage the interaction:
Taking Dolonex IM 20 mg Injection 1 ml with Teriflunomide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of hunger, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
PiroxicamRofecoxib
Severe
How does the drug interact with Dolonex IM 20 mg Injection 1 ml:
Taking Dolonex IM 20 mg Injection 1 ml with Rofecoxib together may lead to side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Taking Dolonex IM 20 mg Injection 1 ml with Rofecoxib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help improve joint flexibility and manage pain.
  • Maintain a healthy weight by engaging in regular low-impact exercises and eating healthy foods.
  • Get adequate sleep, as rest for the muscles can help reduce inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress by meditating, reading, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Dolonex IM 20 mg Injection 1 ml. Alcohol intake, along with Dolonex IM 20 mg Injection 1 ml, may cause increased dizziness. It may also increase the risk of stomach/intestine ulcers and bleeding.

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Pregnancy

Consult your doctor

Avoid taking Dolonex IM 20 mg Injection 1 ml if you are pregnant unless prescribed by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe Dolonex IM 20 mg Injection 1 ml only if the benefits outweigh the risks. Do not take Dolonex IM 20 mg Injection 1 ml in the last 20 weeks of pregnancy as it may cause serious kidney and heart problems in the unborn baby and complications with the pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Dolonex IM 20 mg Injection 1 ml. Please consult your doctor if you have any concerns.

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Driving

Caution

Dolonex IM 20 mg Injection 1 ml may cause dizziness. Do not drive or operate heavy machinery if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed. Dolonex IM 20 mg Injection 1 ml should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Dolonex IM 20 mg Injection 1 ml should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Dolonex IM 20 mg Injection 1 ml is not recommended for children, as the efficacy and safety have not been established.

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Heart

Caution

Dolonex IM 20 mg Injection 1 ml should be used with caution in patients with heart problems. Therefore, please consult your doctor before using Dolonex IM 20 mg Injection 1 ml.

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Geriatrics

Consult your doctor

Dolonex IM 20 mg Injection 1 ml should be used with caution and may require dose adjustment in elderly patients. Please consult your doctor if you have any concerns.

FAQs

Dolonex IM 20 mg Injection 1 ml belongs to the group of medications known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms like pain and inflammation associated with rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders.

Dolonex IM 20 mg Injection 1 ml works by blocking the effect of chemical messengers (prostaglandin), thereby reducing pain, stiffness, swelling, and inflammation.

Diarrhoea might be a side-effect of Dolonex IM 20 mg Injection 1 ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not use Dolonex IM 20 mg Injection 1 ml immediately before or after bypass surgery. Dolonex IM 20 mg Injection 1 ml may increase the risk of heart attack or stroke. Therefore, inform your doctor if you have heart problems.

Dolonex IM 20 mg Injection 1 ml may be used to treat musculoskeletal pain. Musculoskeletal pain refers to the pain in the bones, muscles, ligaments, and tendon.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Other Info - DOL0004

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