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  3. Diof DS Suspension 30 ml

Diof DS Suspension 30 ml, Pack of 1 Suspension
Diof DS Suspension 30 ml, Pack of 1 Suspension
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Diof DS Suspension is used to treat various bacterial infections. It is also effective in treating diarrhoea due to mixed infections and dysentery caused by amoebas. It contains Ofloxacin and Metronidazole, which work by killing the bacteria and parasites responsible for the infections. In some cases, you may experience side effects such as nausea, vomiting, stomach upset, loss of appetite, dry mouth, and a metallic taste. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Composition :

METRONIDAZOLE-200MG + OFLOXACIN-100MG

Manufacturer/Marketer :

Zuventus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Diof DS Suspension

Diof DS Suspension is a combination of antibacterial (ofloxacin) and anti-amoebic (metronidazole) medication used to treat various infections caused by bacteria. It is also effective in treating diarrhoea due to mixed infections and amoebic dysentery. A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our bodies. Diarrhoea is an increase in the frequency of bowel movements, resulting in loose and watery stools. Amoebic dysentery (Also Known as Amoebiasis) is an intestinal infection caused by the parasite Entamoeba histolytica.

Diof DS Suspension is a combination of two antibiotics that include Ofloxacin and Metronidazole. Ofloxacin prevents the division of bacterial cells and inhibits their repair mechanism, leading to the death of the bacteria. Metronidazole kills parasites and anaerobic bacteria that cause infections. It works by damaging their DNA. Both antibiotics are bactericidal in nature and work together to effectively treat the infection.

Take Diof DS Suspension exactly as prescribed. Your doctor will recommend how often you take Diof DS Suspension based on your medical condition. In some cases, you may experience common side effects, including nausea, vomiting, stomach upset, loss of appetite, dry mouth, a metallic taste, headache, dizziness, drowsiness, and confusion. Most of these side effects of Diof DS Suspension do not require medical attention and typically resolve on their own over time. However, if the side effects are persistent, reach out to your doctor.

It is not advisable to stop taking Diof DS Suspension suddenly to avoid unpleasant side effects. The full course prescribed by the doctor should be completed. Inform your doctor if you have any lung disease, epilepsy, difficulty sleeping (sleep apnoea), severe liver disease, or problems with alcohol or other prescription or recreational drugs. Diof DS Suspension should not be used by pregnant women (especially during the first trimester), breastfeeding mothers, and patients with liver diseases, low blood white cells (leukopenia), seizures (fits), gastrointestinal diseases (like Crohn's disease and inflammatory bowel disease), and other neurological diseases. Diof DS Suspension may cause dizziness and drowsiness; therefore, avoid driving and operating machinery until you are mentally alert.

Uses of Diof DS Suspension

Diof DS Suspension is used in the treatment of various bacterial and parasitic infections. Its detailed uses are as follows:<br/> • Bacterial Infections: Diof DS Suspension is effective in treating bacterial infections of the lungs, skin, prostate, urinary tract (kidneys and bladder), and gastrointestinal tract (stomach and intestines).<br/> • Diarrhoea Due to Mixed Infections: Diof DS Suspension is prescribed for the treatment of diarrhoea caused by a combination of bacterial and parasitic organisms, such as those caused by Giardia lamblia (a parasite) and Clostridium difficile (a bacteria).<br/> • Amoebic Dysentery (Amoebiasis): Diof DS Suspension is also effective in treating intestinal amoebiasis caused by Entamoeba histolytica, a parasite that leads to diarrhoea and dysentery.<br/> • Gynaecological Infections: Diof DS Suspension helps in managing pelvic inflammatory disease (caused by sexually transmitted infections like gonorrhoea and chlamydia) and vaginosis (caused by an imbalance of bacteria in the vagina).<br/> • Post-Surgical Infections: Diof DS Suspension may also be used to treat or prevent bacterial infections after certain abdominal or gynaecological surgeries.<br/>

Directions for Use

  • Diof DS Suspension may be taken with or without food (excluding dairy), but taking it with food may lessen stomach discomfort.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Diof DS Suspension as a whole with a glass of water.
  • Do not break, crush, or chew it.

Medicinal Benefits

Diof DS Suspension is used to treat various bacterial infections affecting the lungs, skin, prostate, urinary tract, and gastrointestinal tract. It is also effective in treating diarrhoea caused by mixed infections (involving both bacteria and parasites) and amoebic dysentery. It is a combination of two antibiotics: Ofloxacin and Metronidazole. Ofloxacin (an antibacterial) prevents the division of bacterial cells and inhibits their repair mechanism, leading to the death of the bacteria. Metronidazole kills parasites and anaerobic bacteria that cause infections. It works by damaging their DNA. Both antibiotics are bactericidal in nature and work together to treat the infection effectively.

How Diof DS Suspension Works

Diof DS Suspension is a combination of two antibiotics: Ofloxacin and Metronidazole. Ofloxacin works by preventing bacterial cell division and inhibiting their repair mechanisms, ultimately leading to bacterial cell death. Metronidazole is effective against parasites and anaerobic bacteria; it works by damaging their DNA, resulting in their elimination. Both antibiotics are bactericidal in nature and act synergistically to effectively treat a wide range of infections.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Diof DS Suspension

Do not take more than the prescribed dose of Diof DS Suspension. Taking extra medication will not improve your symptoms and may lead to poisoning or serious side effects. If you suspect an overdose or experience any adverse effects, seek immediate medical attention at the nearest emergency department.

Drug Warnings

If you are allergic to ofloxacin, metronidazole, or any other antibacterial or anti-amoebic agents, please inform your doctor to avoid any unwanted side effects like swallowing or breathing problems, swelling of your lips, face, throat, or tongue. Taking Diof DS Suspension may increase the chances of developing tendinitis (swelling of a tissue that joins a bone to a muscle) or a tendon rupture. Dairy products should be avoided along with Diof DS Suspension. Additionally, exposure to sunlight should be avoided while taking Diof DS Suspension, as it may increase phototoxicity or photosensitivity. Patients with an irregular heartbeat (QT prolongation) should tell their doctor before taking Diof DS Suspension. Diof DS Suspension should not be given to the pregnant mother (during the first trimester) and in nursing mothers as it passes into the breast milk. Please inform your doctor before taking Diof DS Suspension if you have a history of liver disease, low blood white cells (leukopenia), a joint or tendon disorder (such as rheumatoid arthritis), seizures (fits), gastrointestinal diseases (like Crohn's disease and Inflammatory bowel disease), or other neurological diseases. Diof DS Suspension may cause dizziness and drowsiness; therefore, avoid driving and operating machinery until you are mentally alert. Avoid alcohol consumption while taking Diof DS Suspension, as it may increase the risk of side effects like dizziness and drowsiness.

Drug-Drug Interactions

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MetronidazoleEthanol
Critical
MetronidazoleDisulfiram
Critical

Drug-Drug Interactions

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MetronidazoleEthanol
Critical
How does the drug interact with Diof DS Suspension 30 ml:
Drinking alcohol while taking Diof DS Suspension 30 ml can increase the risk or severity of side effects.

How to manage the interaction:
Taking Diof DS Suspension 30 ml with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleDisulfiram
Critical
How does the drug interact with Diof DS Suspension 30 ml:
Coadministration of Disulfiram with Diof DS Suspension 30 ml can increase the risk of side effects.

How to manage the interaction:
Taking Diof DS Suspension 30 ml and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
MetronidazoleAmprenavir
Critical
How does the drug interact with Diof DS Suspension 30 ml:
Co-administration of Amprenavir with Diof DS Suspension 30 ml can increase the risk or severity of side effects.

How to manage the interaction:
Taking Diof DS Suspension 30 ml with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinDronedarone
Critical
How does the drug interact with Diof DS Suspension 30 ml:
Coadministration of Diof DS Suspension 30 ml with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Diof DS Suspension 30 ml with Dronedarone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinZiprasidone
Critical
How does the drug interact with Diof DS Suspension 30 ml:
Coadministration of Diof DS Suspension 30 ml with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Diof DS Suspension 30 ml with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinQuinidine
Critical
How does the drug interact with Diof DS Suspension 30 ml:
Coadministration of Diof DS Suspension 30 ml with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Diof DS Suspension 30 ml with Quinidine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinHalofantrine
Critical
How does the drug interact with Diof DS Suspension 30 ml:
Using halofantrine together with Diof DS Suspension 30 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Diof DS Suspension 30 ml with Halofantrine can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinSaquinavir
Critical
How does the drug interact with Diof DS Suspension 30 ml:
Coadministration of Diof DS Suspension 30 ml with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Diof DS Suspension 30 ml with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinDisopyramide
Critical
How does the drug interact with Diof DS Suspension 30 ml:
Coadministration of Diof DS Suspension 30 ml with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Diof DS Suspension 30 ml with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinBepridil
Critical
How does the drug interact with Diof DS Suspension 30 ml:
Using bepridil together with Diof DS Suspension 30 ml drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Diof DS Suspension 30 ml with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid consuming excessive amounts of caffeine-containing products, such as coffee, tea, energy drinks, cola, or chocolate. Diof DS Suspension may increase nervousness, sleeplessness, and anxiety caused by caffeine.
  • Probiotics should be taken after completing the full course of Diof DS Suspension to help restore healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods, such as yoghurt, cheese, sauerkraut, kombucha, and kimchi, can help restore the gut's beneficial bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains, such as whole-grain bread and brown rice, should be included in your diet. Make sure to drink plenty of water or other fluids every day while you are taking Diof DS Suspension.
  • Avoid the intake of alcoholic beverages, as they can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Diof DS Suspension in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Diof DS Suspension Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Alcohol should not be consumed while taking Diof DS Suspension, as it may increase the risk of side effects like dizziness and drowsiness.

bannner image

Pregnancy

Unsafe

Diof DS Suspension should not be taken during pregnancy, especially during the first trimester, as it may cause harm to the fetus. If you become pregnant while taking Diof DS Suspension, stop taking the medication, and contact your doctor immediately.

bannner image

Breast Feeding

Unsafe

Diof DS Suspension may pass into the breast milk, so avoid taking Diof DS Suspension while breastfeeding.

bannner image

Driving

Unsafe

Diof DS Suspension can cause dizziness, confusion, and drowsiness. Therefore, avoid driving or operating machinery unless you are mentally alert and competent.

bannner image

Liver

Consult your doctor

Diof DS Suspension to be taken with caution, especially if you have a history of liver diseases. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Consult your doctor

Diof DS Suspension to be taken with caution, especially if you have a history of kidney diseases. The dose may have to be adjusted by your doctor.

bannner image

Children

Safe if prescribed

Diof DS Suspension can be given to the children if prescribed by a doctor.

Have a query?

FAQs

Diof DS Suspension is a combination of two antibiotics that include Ofloxacin and Metronidazole. Ofloxacin prevents the division of bacterial cells and inhibits their repair mechanism, leading to the death of the bacteria. Metronidazole kills parasites and anaerobic bacteria that cause infections. It works by damaging their DNA. Both antibiotics are bactericidal in nature and work together to treat the infection effectively.

Diof DS Suspension is a combination of antibacterial (ofloxacin) and anti-amoebic (metronidazole) medication used to treat various infections caused by bacteria. It is also effective in treating diarrhoea due to mixed infections and amoebic dysentery.

It is not advised to take alcohol with Diof DS Suspension. Taking alcohol while taking Diof DS Suspension can cause serious side effects such as headaches, feeling or being sick, pain in the stomach, hot flushes, a fast or irregular heartbeat, dizziness, drowsiness, etc.

Diof DS Suspension can make your skin sensitive to sunlight, a condition known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In the event of an emergency, always wear sunscreen before going outdoors.

If you miss a dose of Diof DS Suspension, take it as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for the missed one.

No. Diof DS Suspension is an antibacterial medicine that acts only against bacterial infections, not against viral infections. You should not take it without consulting your doctor first. Self-medication is dangerous and can lower the efficacy of Diof DS Suspension, leading to antibiotic resistance.

Yes, intake of Diof DS Suspension may cause dry mouth, and you may feel thirsty frequently. Try to drink plenty of fluids (water with electrolytes) and probiotics. You may also experience dry lips, for which you can use lip balm.

Avoid intake of Diof DS Suspension if you have a history of liver diseases, low blood white cells (leukopenia), seizures (fits), gastrointestinal diseases (like Crohn's disease, Inflammatory bowel disease), and other neurological diseases.

The common side effects of Diof DS Suspension include nausea, vomiting, stomach upset, loss of appetite, dry mouth, a metallic taste, headache, dizziness, drowsiness, and confusion. Most of these side effects of Diof DS Suspension do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

Office No. 5119, 5th Floor, 'D' Wing, Oberoi Garden Estates, Chandivili, Andheri (E), Mumbai - 400 072
Other Info - DIO0012

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 22, 2025 | 1:12 PM IST

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Reference

  1. https://jbpharma.com/wp-content/uploads/2021/11/Metrogyl-O-Tablets_PI_India_October-2021.pdf
  2. https://www.drugs.com/mtm/ofloxacin.html
  3. https://www.drugs.com/metronidazole.html
  4. https://www.drugs.com/drug-interactions/metronidazole-with-ofloxacin-1617-0-1741-0.html
  5. https://www.medicines.org.uk/emc/product/12817/pilhttp://medicines.org.uk/emc/product/8481/smpc
  6. https://medlineplus.gov/druginfo/meds/a691005.html
  7. https://medlineplus.gov/druginfo/meds/a689011.html

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