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compositionComposition:TERIFLUNOMIDE-14MG
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Denopsy 14 mg Tablet is used to treat relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. It contains Teriflunomide, which works by decreasing inflammation and the action of immune cells that cause nerve damage. Thus, it helps treat multiple sclerosis. Sometimes, Denopsy 14 mg Tablet may cause side effects such as headache, nausea, diarrhoea, and hair loss.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

TERIFLUNOMIDE-14MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Denopsy 14 mg Tablet

Denopsy 14 mg Tablet is a prescription oral medicine used to manage relapsing forms of multiple sclerosis (MS) in adults. Its primary medical purpose is to help reduce the frequency of clinical relapses and slow down the physical worsening of the condition. By keeping the disease activity under control, it supports your daily physical functioning.

This medication is taken once daily and should be taken consistently at the same time each day to maintain stable levels in your body. You can take it with or without food. To achieve the best results, it is helpful to support your treatment with structured lifestyle habits, such as regular physical therapy and a balanced diet designed to manage chronic inflammation.

While taking Denopsy 14 mg Tablet , you may experience common side effects like temporary hair thinning, diarrhoea, or nausea. However, it is vital to contact your doctor immediately if you notice serious symptoms, such as severe upper stomach pain, yellowing of the skin or eyes, or unusual bruising, which can point to more severe underlying issues.

Do not take this if you are pregnant, planning to become pregnant, or have severe liver problems. Before starting this treatment, always tell your doctor if you have a history of chronic infections, high blood pressure, or lung disease, as this medicine may not be suitable for you.

This medicine can interact with other drugs, including certain vaccines and therapies that affect your immune system. You should also avoid drinking alcohol during treatment because both alcohol and this medicine can strain your liver. If you are breastfeeding, elderly, or planning a family, speak with your healthcare provider to discuss safe usage guidelines.

Uses of Denopsy 14 mg Tablet

Your doctor may prescribe Denopsy 14 mg Tablet to help manage the following conditions:

  • Relapsing Multiple Sclerosis (RMS): Denopsy 14 mg Tablet is used to treat relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, by reducing the frequency of symptom flare-ups.
  • Delaying Disability Progression: Denopsy 14 mg Tablet helps slow down the physical worsening and functional decline associated with multiple sclerosis over time.

Key Benefits

When used as directed as part of your treatment plan, this medicine may provide the following benefits:

  • Reduces Multiple Sclerosis Relapses: Using Denopsy 14 mg Tablet can help you experience longer periods of stable health between multiple sclerosis relapses. By keeping symptoms under control, it allows you to maintain your daily physical routines with fewer interruptions.
  • Helps Preserve Mobility: This medicine helps preserve your physical mobility and independence by protecting the central nervous system from ongoing inflammatory damage. This delay in disability progression contributes to a better quality of life over the long term.
  • Convenient Once-Daily Tablet: As a once-daily oral tablet, Denopsy 14 mg Tablet offers a convenient alternative to injectable therapies. This simple dosing routine makes it easier to stay consistent with your prescribed treatment plan.

Directions for Use

  • Denopsy 14 mg Tablet can be taken with or without food.
  • Recommended once daily or as advised by your doctor.
  • Swallow Denopsy 14 mg Tablet as a whole with a glass of water.
  • Do not chew or break Denopsy 14 mg Tablet .

How Denopsy 14 mg Tablet Works

The active ingredient in Denopsy 14 mg Tablet is teriflunomide, an immunomodulator (a medicine that adjusts how your immune system behaves without completely suppressing it). This medicine reduces the number of overactive immune cells that mistakenly attack the protective covering of your nerves. It does this by temporarily blocking a specific mitochondrial enzyme called dihydroorotate dehydrogenase (an enzyme that helps certain immune cells multiply rapidly). As a result, specific white blood cells (called T and B cells) cannot multiply as quickly, helping reduce the immune attack linked to multiple sclerosis. By limiting these overactive immune cells, the medicine reduces inflammation in the brain and spinal cord, helping lower the number of relapses and slow disease progression
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Alcohol

Consult your doctor

It is unknown if Denopsy 14 mg Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Teriflunomide belongs to pregnancy category X. Do not take Denopsy 14 mg Tablet if you are pregnant, planning for pregnancy or think you may be pregnant.

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Breast Feeding

Unsafe

Teriflunomide may pass into breast milk. Your doctor will make a decision whether to discontinue nursing or the medicine, taking into account the importance of the medicine to the mother.

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Driving

Caution

Denopsy 14 mg Tablet may cause dizziness. So, drive or operate machinery only if you are alert.

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Liver

Caution

Denopsy 14 mg Tablet is not recommended in patients with severe liver impairment. If you have a history of liver disease, inform your doctor before taking Denopsy 14 mg Tablet .

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Kidney

Caution

Do not take Denopsy 14 mg Tablet if you have a serious kidney problem which requires dialysis. If you have a history of kidney disease, inform your doctor before taking Denopsy 14 mg Tablet .

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Children

Caution

Denopsy 14 mg Tablet is not recommended for children as the safety and effectiveness have not been established.

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Heart

Caution

Denopsy 14 mg Tablet is not recommended in patients with severe heart problems. If you have a history of heart disease, inform your doctor before taking Denopsy 14 mg Tablet .

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Geriatrics

Consult your doctor

Limited information available about the use of Denopsy 14 mg Tablet in geriatric patients. Please consult your physician.

What if I have taken an overdose of Denopsy 14 mg Tablet

If you suspect an overdose, seek emergency medical help immediately. Medical professionals may use specific medications, such as activated charcoal or cholestyramine, to quickly bind and remove the drug from your system.

Diet & Lifestyle Advise

  • Prioritise liver health: Avoid or strictly limit your intake of alcohol while on this medication, as combining them increases the risk of severe liver damage.
  • Incorporate low-impact exercise: Engage in gentle physical activities like swimming, walking, or stretching to help preserve your balance, muscle strength, and flexibility.
  • Manage body temperature: Since heat can temporarily worsen multiple sclerosis symptoms, try to stay cool by taking lukewarm showers and avoiding extreme outdoor heat.
  • Eat an anti-inflammatory diet: Focus on whole foods rich in omega-3 fatty acids, leafy greens, and lean proteins to support your overall neurological health.
  • Practice infection prevention: Wash your hands frequently and avoid close contact with individuals who have active infections, as this medicine can temporarily lower your white blood cell count.
health query

Have a query?

How Soon It Starts Working

The time required for Denopsy 14 mg Tablet to start to work: The time required for Denopsy 14 mg Tablet to show its action is not clinically established. The time for which the effects of Denopsy 14 mg Tablet last: The duration of action for Denopsy 14 mg Tablet is not clinically established.

What if you forget to take Denopsy 14 mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Denopsy 14 mg Tablet at room temperature, strictly between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Complete your liver tests: Ensure you undergo all scheduled blood tests before starting and during your treatment, as your doctor must check your liver enzymes regularly.
  • Use effective birth control: Both men and women must use reliable contraception during treatment. Without a medical washout procedure, the active drug can take up to two years to completely leave your body. If pregnancy is planned, your doctor may recommend an accelerated elimination (washout) procedure using medicines such as cholestyramine or activated charcoal to remove it more quickly.
  • Check your blood pressure: Monitor your blood pressure regularly at home and report any significant increases to your healthcare provider.
  • Avoid live vaccines: Do not receive any live vaccines while taking this medicine and for a period after stopping, as your body’s immune response may be reduced.
  • Report nerve pain: Alert your doctor immediately if you develop new or worsening numbness, tingling, or a burning sensation in your limbs.

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  • May Interact with Other Medicines: May increase the levels and side effects of other drugs in your body, such as warfarin, certain cholesterol-lowering medicines (like atorvastatin or rosuvastatin), and some cancer treatments.
  • Some Medicines May Reduce Effectiveness: Certain medications, such as rifampin, can speed up the removal of Denopsy 14 mg Tablet from your body, potentially making it less effective.

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Habit Forming

No

Therapeutic Class

[IMMUNOMODULATORS]

FAQs

Denopsy 14 mg Tablet is used to treat Multiple sclerosis (MS).
Denopsy 14 mg Tablet works by decreasing inflammation and the action of immune cells that cause nerve damage.
Denopsy 14 mg Tablet may cause inflammation of the pancreas. Consult the doctor if you experience nausea, vomiting or pain in the abdomen.
Denopsy 14 mg Tablet may increase blood pressure. Your doctor may monitor blood pressure levels before and during the treatment.
Without a medical washout procedure, teriflunomide can take up to two years to completely leave your body. If it needs to be removed sooner, your doctor can prescribe an accelerated elimination (washout) procedure using medicines such as cholestyramine or activated charcoal, which usually clears the drug within about 11 days. Talk to your doctor before stopping this medication.
No, you must not become pregnant while taking this medicine, as it can cause severe birth defects. If you are a female of childbearing age, you must use reliable birth control during treatment and until the medicine has completely left your body. Without a medical washout procedure, this may take up to two years after stopping treatment. Your doctor can recommend a washout procedure if you plan to become pregnant sooner.
Some patients experience temporary hair thinning or mild hair loss, usually starting within the first six months of treatment. This symptom is typically temporary and often improves over time without stopping the medication. Talk to your doctor or pharmacist if you are concerned about hair changes.
Your doctor will monitor your blood to check your liver enzymes and your white blood cell counts, as this medicine can affect liver function and lower your body's infection-fighting cells. Talk to your doctor about your scheduled testing timeline.
It is highly recommended to avoid or strictly limit alcohol while taking this medicine. Both alcohol and this medication can put stress on your liver, and using them together significantly increases the risk of liver damage. Talk to your doctor or pharmacist about safe lifestyle choices.
No, Denopsy 14 mg Tablet is not a chemotherapy drug. It is a disease-modifying therapy classified as an immunomodulator, meaning it adjusts how your immune system behaves without completely suppressing it. It specifically targets the overactive immune cells that contribute to multiple sclerosis symptoms.
The active drug can pass into semen. If you are planning to father a child, you must talk to your doctor, who may recommend stopping the medication and undergoing a washout procedure to safely clear the drug first. Talk to your doctor before making family planning decisions.
You must avoid receiving live vaccines during treatment and for some time after stopping, as your immune system may not respond safely. Non-live vaccines are generally safe but might be less effective while you are on this therapy. Talk to your doctor or pharmacist before getting any vaccination.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - DEN0327
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