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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Dabiclot 75 Capsule is used to prevent the formation of blood clots. It contains Dabigatran etexilate mesylate which works by blocking coagulation factor (thrombin) in the blood and prevents blood clot formation. In some cases, this medicine may cause side effects such as bleeding, stomach pain, nausea, and indigestion. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dabiclot 75 Capsule

Dabiclot 75 Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Dabiclot 75 Capsule is primarily used to prevent stroke (blood clots in the brain). It is also used to prevent and treat deep vein thrombosis (blood clots in leg veins), and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

Dabiclot 75 Capsule contains Dabigatran etexilate mesylate, which is a new oral blood thinner. It works by blocking a substance (a protein known as thrombin) in the blood and prevents blood clot formation. Therefore, Dabiclot 75 Capsule preventing blood clot formation in the body.

Take Dabiclot 75 Capsule as prescribed by your doctor. You are advised to take Dabiclot 75 Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience bleeding, stomach pain, nausea, and indigestion. Most of these side effects of Dabiclot 75 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Dabiclot 75 Capsule or any other medicines, please tell your doctor. Dabiclot 75 Capsule should not be taken in the conditions like bleeding disorder, or kidney disease. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Dabiclot 75 Capsule . Dabiclot 75 Capsule should not be used for children below 18 years of age. Dabiclot 75 Capsule has no known effects on the ability to drive and use machines. It is advisable for you to avoid alcohol consumption with Dabiclot 75 Capsule as it may increase the risk of bleeding.

Uses of Dabiclot 75 Capsule

Prevention of blood clot

Directions for Use

• Dabiclot 75 Capsule can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Dabiclot 75 Capsule as a whole with a glass of water.• Do not open, break, or chew it.

Medicinal Benefits

Dabiclot 75 Capsule belongs to a class of drugs known as anticoagulants or blood thinners. Dabiclot 75 Capsule is primarily used to prevent stroke (blood clots in the brain). It is also used to prevent blood clots in the heart and prevent heart attacks. Besides this Dabiclot 75 Capsule is also used to prevent and treat deep vein thrombosis (blood clots in leg veins), and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. This Dabiclot 75 Capsule may also be used to prevent the formation of blood clots after hip replacement surgery. It works by blocking a substance (a protein known as thrombin) in the blood and prevents blood clot formation. Therefore, Dabiclot 75 Capsule prevents blood clot formation in the body.

How Dabiclot 75 Capsule Works

Dabiclot 75 Capsule contains Dabigatran etexilate mesylate, which is a new oral blood thinner. It works by blocking a substance (a protein known as thrombin) in the blood and prevents blood clot formation. Therefore, Dabiclot 75 Capsule preventing blood clot formation in the body.

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Dabiclot 75 Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • You can take your medicine with meals to lower the chances of getting stomach pain.
  • Avoid foods that are acidic, spicy, sugary, or greasy.
  • Eat foods that are easily digestible such as rice, toast, and bananas.
  • Eat your meals in smaller amounts throughout the day to prevent strain on your stomach and digestion.
  • Drink water or fluids to stay hydrated and prevent stomach upset.
  • Use a heating pad or massage your stomach area.
  • Engage in mild physical activities such as yoga and walking.

What if I have taken an overdose of Dabiclot 75 Capsule

Take Dabiclot 75 Capsule only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include unusual/prolonged bleeding, bloody/tarry/black stools, and pink/dark urine. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are known to be allergic to Dabiclot 75 Capsule or any other medicines, please tell your doctor. Dabiclot 75 Capsule should not be taken in the conditions like heart disease, bleeding problems, and kidney disease. Do not take Dabiclot 75 Capsule if you have reduced function of the liver, which might cause death. Inform your doctor if you have a serious injury (bone fracture, head injury). People who have any spinal surgery are more likely to have bleeding problems around the spine when already on this Dabiclot 75 Capsule . This bleeding infrequently occurs but can lead to not moving the body (paralysis) prolonged-term or paralysis that will not go away. Dabiclot 75 Capsule should not be taken if you are older than 75 years. Before taking Dabiclot 75 Capsule inform your doctor if you have a surgery in the past month. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Dabiclot 75 Capsule .  Dabiclot 75 Capsule should not be used for children below 18 years of age. Dabiclot 75 Capsule has no known effects on the ability to drive and use machines. It is advisable for you to avoid alcohol consumption with Dabiclot 75 Capsule as it may increase the risk of bleeding.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dabiclot 75 Capsule:
When Mifepristone is taken with Dabiclot 75 Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Dabiclot 75 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dabiclot 75 Capsule:
When Dabiclot 75 Capsule is taken with Dronedarone, the amount of Dabiclot 75 Capsule in the blood can go up.

How to manage the interaction:
Taking Dabiclot 75 Capsule with Dronedarone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor.
How does the drug interact with Dabiclot 75 Capsule:
Taking Dabiclot 75 Capsule with Tirofiban can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabiclot 75 Capsule with Tirofiban together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabiclot 75 Capsule:
Taking Dabiclot 75 Capsule with Acalabrutinib can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabiclot 75 Capsule with Acalabrutinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabiclot 75 Capsule:
Taking Dabiclot 75 Capsule with Abciximab can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabiclot 75 Capsule with Abciximab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabiclot 75 Capsule:
Taking Flurbiprofen with Dabiclot 75 Capsule can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Flurbiprofen and Dabiclot 75 Capsule together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience bleeding, feeling dizzy or lightheaded, dark or sticky stools, throwing up blood, severe headache, or feeling weak contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Dabiclot 75 Capsule:
Taking Dabiclot 75 Capsule with rifampicin can decrease the blood levels of Dabiclot 75 Capsule, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Dabiclot 75 Capsule and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Dabiclot 75 Capsule:
Taking Dabiclot 75 Capsule with Defibrotide can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabiclot 75 Capsule with Defibrotide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabiclot 75 Capsule:
Taking Dabiclot 75 Capsule with Alteplase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabiclot 75 Capsule with Alteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Dabiclot 75 Capsule:
Combining Sulindac with Dabiclot 75 Capsule can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Taking Dabiclot 75 Capsule with Sulindac together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DABIGATRAN ETEXILATE MESILATE-75MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN ETEXILATE MESILATE-75MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Dabiclot 75 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Dabiclot 75 Capsule treatment.

Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.
  •  Opt for high vitamin K foods (liver, leafy green vegetables, or vegetable oils) as Dabiclot 75 Capsule may lower Vitamin K in your body.
  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Dabiclot 75 Capsule and lead to unwanted side effects. Hence try to avoid these juices while taking Dabiclot 75 Capsule .
  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Dabiclot 75 Capsule Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Dabiclot 75 Capsule as it may increase the risk of bleeding.

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Pregnancy

Caution

Dabiclot 75 Capsule is a Category C pregnancy drug as the effect of Dabiclot 75 Capsule is unknown on the mother and the unborn baby. Avoid the use of Dabiclot 75 Capsule if you are pregnant and inform your doctor.

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Breast Feeding

Unsafe

Dabiclot 75 Capsule should not be used while taking Dabiclot 75 Capsule . Inform your doctor if you are a breastfeeding mother.

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Driving

Safe if prescribed

Dabiclot 75 Capsule usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Dabiclot 75 Capsule with caution, especially if you have a history of Liver diseases/conditions. Dabiclot 75 Capsule may increase the chances of mild liver injury. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Dabiclot 75 Capsule with caution, especially if you have a history of Kidney diseases/conditions, as this Dabiclot 75 Capsule may cause side effects. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Dabiclot 75 Capsule should not be used for children below 18 years as it is not approved for children.

Have a query?

FAQs

Dabiclot 75 Capsule is used to prevent blood clots. It is used to prevent and treat deep vein thrombosis (blood clots in leg veins), and pulmonary embolism (blood clots in the lung).

People experiencing any uncommon bleeding or people allergic to Dabiclot 75 Capsule should not take Dabiclot 75 Capsule . People with artificial heart valves should also prevent Dabiclot 75 Capsule . Dabiclot 75 Capsule should not take those patients who have bleeding problems and heart disease. The use of this Dabiclot 75 Capsule is not suggested in patients with serious kidney disease.

As compared to other blood thinner medicines, Dabiclot 75 Capsule does not normally cause hair loss. Though, there do exist some unusual reports of hair loss related to Dabiclot 75 Capsule . Inform your doctor if you observe hair loss while taking Dabiclot 75 Capsule .

Yes, Dabiclot 75 Capsule increases the risk of bleeding. Always be cautious while doing activities that may lead to an injury or bleeding. Inform your doctor immediately if you notice any abnormal staining or bleeding.

Dabiclot 75 Capsule works by blocking a substance (a protein known as thrombin) in the blood and preventing blood clot formation. Therefore, Dabiclot 75 Capsule preventing blood clot formation in the body.

Unlike other blood thinners, Dabiclot 75 Capsule generally does not affect the functioning of the liver. But long-term use of Dabiclot 75 Capsule may raise the chances of mild liver injury in patients with a high level of liver enzymes. However, the complete chances of developing any such problem are lesser than other blood thinners. It is advisable to you that before starting this Dabiclot 75 Capsule inform your doctor if you have a history of liver disease.

Dabiclot 75 Capsule may increase the risk of bleeding during surgery. Therefore, the doctor might ask you to stop taking Dabiclot 75 Capsule a few days before surgery.

You can take Dabiclot 75 Capsule with or without food but try to take it at the same time every day. Dabiclot 75 Capsule should be swallowed as a whole with water; do not crush or chew it.

Dabiclot 75 Capsule should be taken as advised by the doctor. To help you remember to take Dabiclot 75 Capsule , take it at around the same time daily.

You are recommended to avoid alcohol consumption with Dabiclot 75 Capsule as it may increase the risk of bleeding.

Though Dabiclot 75 Capsule starts working within a few hours of taking the medicine, you may not feel any better. Keep taking Dabiclot 75 Capsule for the prescribed duration to treat your condition effectively.

Store Dabiclot 75 Capsule at room temperature, in a dry place. Keep out of sight and reach of children.

Dabiclot 75 Capsule may cause side effects like bleeding, stomach pain, nausea, and indigestion. Most of these side effects of Dabiclot 75 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - DAB0386

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