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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Crixan 125 mg Suspension is used to treat a wide range of bacterial infections. It contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for bacterial cell growth. As a result, bacterial cells are not able to reproduce and grow. Thus, it helps prevent infections. Common side effects of Crixan 125 mg Suspension are feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping.

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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Crixan 125 mg Suspension

Crixan 125 mg Suspension belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Antibiotics inhibit the growth of microorganisms and are given to treat bacterial infections.

Crixan 125 mg Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Crixan 125 mg Suspension helps in the prevention of infections.

Like all medicines, Crixan 125 mg Suspension may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping. Most of these side effects do not require medical attention and gradually resolve over time. However, if you notice any of these side effects persist or worsen your child’s condition, inform your doctor immediately.

Inform your doctor about your child's entire medical history. Other drugs or supplements should not be combined with Crixan 125 mg Suspension unless prescribed by a doctor. Even if your child is feeling better, do not miss any dose and complete the entire course of medication. Stopping the medication too soon may cause the infection to recur or worsen.

Uses of Crixan 125 mg Suspension

Crixan 125 mg Suspension is used in the treatment of Bacterial infections. The detailed uses of Crixan 125 mg Suspension are as follows:<br/>• Respiratory Tract Infections: Crixan 125 mg Suspension is prescribed to treat infections like bronchitis and community-acquired pneumonia. It works by stopping the growth of bacteria in the lungs and airways, helping relieve symptoms such as cough, fever, and breathing difficulty.<br/>• Ear, Nose, and Throat Infections: Crixan 125 mg Suspension is effective in managing conditions like otitis media (middle ear infection), sinusitis, pharyngitis, and tonsillitis. It helps reduce inflammation, ear pain, sore throat, and fever by eliminating the causative bacteria.<br/>• Skin and Soft Tissue Infections: Crixan 125 mg Suspension treats mild to moderate skin infections such as cellulitis, impetigo, and infected wounds. It works by targeting the bacteria responsible, reducing redness, swelling, and promoting healing.<br/>• Dental and Oral Infections: Crixan 125 mg Suspension may be used to treat bacterial infections in the teeth and gums, such as dental abscesses, by controlling bacterial growth and reducing pain and swelling.<br/>• Infections in Immunocompromised Children: Crixan 125 mg Suspension can be used to treat or prevent infections like Mycobacterium avium complex (MAC) in children with weakened immune systems, such as those with HIV.<br/>

Directions for Use

• Crixan 125 mg Suspension can be administered with or without food as directed by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Administer the prescribed dose to the child using the measuring cup/dosing syringe/dropper.• Shake well before use.

Medicinal Benefits

Crixan 125 mg Suspension belongs to the macrolide class of antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori).

How Crixan 125 mg Suspension Works

Crixan 125 mg Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Crixan 125 mg Suspension helps in the prevention of infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep Crixan 125 mg Suspension out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Crixan 125 Suspension 30 ml
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Crixan 125 mg Suspension

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Crixan 125 mg Suspension may include severe stomach pain, nausea, vomiting, and diarrhea. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Before using Crixan 125 mg Suspension, let your doctor know about all your children's medical conditions, sensitivities, and all medications used. Do not use any other drugs or supplements with Crixan 125 mg Suspension unless prescribed by the doctor. Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Crixan 125 mg Suspension in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Crixan 125 mg Suspension and iron supplements and antacids.

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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How does the drug interact with Crixan 125 Suspension 30 ml:
Using Lurasidone together with Crixan 125 Suspension 30 ml may result in significantly higher Lurasidone blood levels. This may increase the possibility of side effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Lurasidone and Crixan 125 Suspension 30 ml may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Naloxegol is taken with Crixan 125 Suspension 30 ml, the amount of Naloxegol in the blood can go up.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Naloxegol can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinAstemizole
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Astemizole is taken with Crixan 125 Suspension 30 ml, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking Crixan 125 Suspension 30 ml with Astemizole is not recommended, please consult your doctor before taking it.
ClarithromycinDihydroergotamine
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Dihydroergotamine is taken with Crixan 125 Suspension 30 ml, the amount of Dihydroergotamine in the blood can go up.

How to manage the interaction:
Taking Crixan 125 Suspension 30 ml with Dihydroergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Crixan 125 Suspension 30 ml:
When Nimodipine is taken with Crixan 125 Suspension 30 ml, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Nimodipine is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heart rhythm, swelling, and low blood pressure, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinFlibanserin
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Flibanserin is taken with Crixan 125 Suspension 30 ml, it can slow down the way Flibanserin is broken down in the body.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Flibanserin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like excessive drowsiness and decreases in blood pressure that can lead to dizziness, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Crixan 125 Suspension 30 ml:
Combining Crixan 125 Suspension 30 ml with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Thioridazine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Crixan 125 Suspension 30 ml:
Co-administration of Eplerenone and Crixan 125 Suspension 30 ml may significantly increase the blood levels and effects of eplerenone.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Crixan 125 Suspension 30 ml with Eplerenone is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.
Critical
How does the drug interact with Crixan 125 Suspension 30 ml:
When Quinidine is taken with Crixan 125 Suspension 30 ml, can increase the blood levels and effects of Quinidine. This may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Crixan 125 Suspension 30 ml and Quinidine can lead to an interaction, it can be taken if advised by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats. However, if you experience any symptoms like headache, confusion, vomiting, diarrhea, ringing in the ears, hearing loss, blurred or double vision, or sensitivity to light, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Crixan 125 Suspension 30 ml:
Taking Rifabutin and Crixan 125 Suspension 30 ml together may increase the blood levels of rifabutin.

How to manage the interaction:
Taking Rifabutin with Crixan 125 Suspension 30 ml is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately If you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to give probiotics after taking the full course of Crixan 125 mg Suspension to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • The BRAT diet (bananas, rice, apple sauce, toast) can help with diarrhoea from antibiotics.
  • Give plenty of water to the child. Staying hydrated is important, especially when you’re child sick.
  • Eating a broad range of plant-based foods such as vegetables, fruits, nuts, seeds, pulses and wholegrains helps to build a healthy gut microbiome.
  • Avoid feeding too many calcium-enriched foods and drinks because they may interfere with the functioning of Crixan 125 mg Suspension.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS
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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Caution

Inform your doctor if your child has liver problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor if your child has kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Crixan 125 mg Suspension can be given safely to children. Give this medicine to your child in the doses prescribed by the paediatrician.

Have a query?

FAQs

Crixan 125 mg Suspension is used to treat Bacterial infections.

Crixan 125 mg Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Crixan 125 mg Suspension helps in the prevention of infections.

After taking antibiotics such as Crixan 125 mg Suspension, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.

Crixan 125 mg Suspension treats only bacterial infections. It will not work for viral infections such as the common cold, or flu.

No, Crixan 125 mg Suspension is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with a doctor&#039;s advice only.

Side effects are rare with Crixan 125 mg Suspension and do not usually last long. They will get better after a day or two. If those side effects persist, reach out to the doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - CRI0006

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