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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cloff Xl 125mg/5ml Suspension is used to treat a wide range of bacterial infections. It contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for bacterial cell growth. As a result, bacterial cells are not able to reproduce and grow. Thus, it helps prevent infections. Common side effects of Cloff Xl 125mg/5ml Suspension are feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping.

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Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Cloff Xl 125mg/5ml Suspension

Cloff Xl 125mg/5ml Suspension belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Antibiotics inhibit the growth of microorganisms and are given to treat bacterial infections.

Cloff Xl 125mg/5ml Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff Xl 125mg/5ml Suspension helps in the prevention of infections.

Like all medicines, Cloff Xl 125mg/5ml Suspension may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping. Most of these side effects do not require medical attention and gradually resolve over time. However, if you notice any of these side effects persist or worsen your child’s condition, inform your doctor immediately.

Inform your doctor about your child's entire medical history. Other drugs or supplements should not be combined with Cloff Xl 125mg/5ml Suspension unless prescribed by a doctor. Even if your child is feeling better, do not miss any dose and complete the entire course of medication. Stopping the medication too soon may cause the infection to recur or worsen.

Uses of Cloff Xl 125mg/5ml Suspension

Cloff Xl 125mg/5ml Suspension is used in the treatment of Bacterial infections. The detailed uses of Cloff Xl 125mg/5ml Suspension are as follows:<br/>• Respiratory Tract Infections: Cloff Xl 125mg/5ml Suspension is prescribed to treat infections like bronchitis and community-acquired pneumonia. It works by stopping the growth of bacteria in the lungs and airways, helping relieve symptoms such as cough, fever, and breathing difficulty.<br/>• Ear, Nose, and Throat Infections: Cloff Xl 125mg/5ml Suspension is effective in managing conditions like otitis media (middle ear infection), sinusitis, pharyngitis, and tonsillitis. It helps reduce inflammation, ear pain, sore throat, and fever by eliminating the causative bacteria.<br/>• Skin and Soft Tissue Infections: Cloff Xl 125mg/5ml Suspension treats mild to moderate skin infections such as cellulitis, impetigo, and infected wounds. It works by targeting the bacteria responsible, reducing redness, swelling, and promoting healing.<br/>• Dental and Oral Infections: Cloff Xl 125mg/5ml Suspension may be used to treat bacterial infections in the teeth and gums, such as dental abscesses, by controlling bacterial growth and reducing pain and swelling.<br/>• Infections in Immunocompromised Children: Cloff Xl 125mg/5ml Suspension can be used to treat or prevent infections like Mycobacterium avium complex (MAC) in children with weakened immune systems, such as those with HIV.<br/>

Directions for Use

• Cloff Xl 125mg/5ml Suspension can be administered with or without food as directed by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Administer the prescribed dose to the child using the measuring cup/dosing syringe/dropper.• Shake well before use.

Medicinal Benefits

Cloff Xl 125mg/5ml Suspension belongs to the macrolide class of antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori).

How Cloff Xl 125mg/5ml Suspension Works

Cloff Xl 125mg/5ml Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff Xl 125mg/5ml Suspension helps in the prevention of infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep Cloff Xl 125mg/5ml Suspension out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Cloff Xl 125mg/5ml Suspension 60ml
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Cloff Xl 125mg/5ml Suspension

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Cloff Xl 125mg/5ml Suspension may include severe stomach pain, nausea, vomiting, and diarrhea. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Before using Cloff Xl 125mg/5ml Suspension, let your doctor know about all your children's medical conditions, sensitivities, and all medications used. Do not use any other drugs or supplements with Cloff Xl 125mg/5ml Suspension unless prescribed by the doctor. Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Cloff Xl 125mg/5ml Suspension in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Cloff Xl 125mg/5ml Suspension and iron supplements and antacids.

Drug-Drug Interactions

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ClarithromycinAstemizole
Critical

Drug-Drug Interactions

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ClarithromycinAstemizole
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
When Astemizole is taken with Cloff Xl 125mg/5ml Suspension 60ml, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking Cloff Xl 125mg/5ml Suspension 60ml with Astemizole is not recommended, please consult your doctor before taking it.
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
The combination of Alprazolam and Cloff Xl 125mg/5ml Suspension 60ml may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Alprazolam and Cloff Xl 125mg/5ml Suspension 60ml, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.
ClarithromycinDroperidol
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
Co-administration of Droperidol with Cloff Xl 125mg/5ml Suspension 60ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Cloff Xl 125mg/5ml Suspension 60ml with Droperidol can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
When Tolvaptan and Cloff Xl 125mg/5ml Suspension 60ml are taken together, may significantly increase the blood levels and effects of Tolvaptan.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Cloff Xl 125mg/5ml Suspension 60ml, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
Co-administration of Cloff Xl 125mg/5ml Suspension 60ml and Sparfloxacin may result in an increased risk of QT interval prolongation.

How to manage the interaction:
Co-administration of Sertraline and Desvenlafaxine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinErgotamine
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
When Ergotamine is taken with Cloff Xl 125mg/5ml Suspension 60ml, the amount of Ergotamine in the blood can go up.

How to manage the interaction:
Taking Cloff Xl 125mg/5ml Suspension 60ml with Ergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
When Naloxegol is taken with Cloff Xl 125mg/5ml Suspension 60ml, the amount of Naloxegol in the blood can go up.

How to manage the interaction:
Co-administration of Cloff Xl 125mg/5ml Suspension 60ml and Naloxegol can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
When Nimodipine is taken with Cloff Xl 125mg/5ml Suspension 60ml, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Cloff Xl 125mg/5ml Suspension 60ml and Nimodipine is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heart rhythm, swelling, and low blood pressure, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
Taking Rifabutin and Cloff Xl 125mg/5ml Suspension 60ml together may increase the blood levels of rifabutin.

How to manage the interaction:
Taking Rifabutin with Cloff Xl 125mg/5ml Suspension 60ml is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately If you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cloff Xl 125mg/5ml Suspension 60ml:
When Alfuzosin and Cloff Xl 125mg/5ml Suspension 60ml can increase the risk or severity of side effects like low blood pressure or irregular heart rates.

How to manage the interaction:
Taking Cloff Xl 125mg/5ml Suspension 60ml with alfuzosin is not recommended as it can result in an interaction; it should be taken only if your doctor has advised it. However, if you experience dizziness, headache, palpitations, or chest discomfort, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to give probiotics after taking the full course of Cloff Xl 125mg/5ml Suspension to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • The BRAT diet (bananas, rice, apple sauce, toast) can help with diarrhoea from antibiotics.
  • Give plenty of water to the child. Staying hydrated is important, especially when you’re child sick.
  • Eating a broad range of plant-based foods such as vegetables, fruits, nuts, seeds, pulses and wholegrains helps to build a healthy gut microbiome.
  • Avoid feeding too many calcium-enriched foods and drinks because they may interfere with the functioning of Cloff Xl 125mg/5ml Suspension.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS
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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Caution

Inform your doctor if your child has liver problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor if your child has kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Cloff Xl 125mg/5ml Suspension can be given safely to children. Give this medicine to your child in the doses prescribed by the paediatrician.

Have a query?

FAQs

Cloff Xl 125mg/5ml Suspension is used to treat Bacterial infections.

Cloff Xl 125mg/5ml Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff Xl 125mg/5ml Suspension helps in the prevention of infections.

After taking antibiotics such as Cloff Xl 125mg/5ml Suspension, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.

Cloff Xl 125mg/5ml Suspension treats only bacterial infections. It will not work for viral infections such as the common cold, or flu.

No, Cloff Xl 125mg/5ml Suspension is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with a doctor&#039;s advice only.

Side effects are rare with Cloff Xl 125mg/5ml Suspension and do not usually last long. They will get better after a day or two. If those side effects persist, reach out to the doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,INDIA
Other Info - CLO1242

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