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compositionComposition:CISATRACURIUM-20MG
prescription
Prescription Medicine
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₹1153 with coupons & bank offers*

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Cisblok 20mg Injection is a non-depolarizing neuromuscular blocking agent used primarily to induce muscle relaxation during surgical procedures or in intensive care settings. It works by blocking the transmission of nerve impulses to the muscles, facilitating endotracheal intubation and improving surgical conditions. Some individuals may experience flushing, slow heartbeat, and low blood pressure.

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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

CISATRACURIUM-20MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Cisblok 20mg Injection

Cisblok 20mg Injection is a prescription injection used to relax the body's muscles during surgery, certain medical procedures, or while you are receiving breathing support with a ventilator in an intensive care unit (ICU). It works by temporarily blocking the signals between your nerves and muscles, allowing your healthcare team to safely place a breathing tube, perform surgery, or provide mechanical ventilation.

This medicine is commonly used to provide muscle relaxation during surgery, make tracheal intubation (placement of a breathing tube) easier, and help patients breathe comfortably with a mechanical ventilator in the ICU. It relaxes only the muscles and does not provide pain relief or make you unconscious, so it is always used together with appropriate anaesthesia or sedation.

Because this medicine is given as an injection in a hospital, it is not used as a regular treatment at home. It is administered as a single injection or a continuous intravenous infusion by trained healthcare professionals only when needed for your procedure. Before surgery, you will usually be asked to avoid eating or drinking for a certain period as instructed by your anaesthesia team.

Some people may develop temporary side effects such as a slow heart rate, low blood pressure, flushing, or mild breathing changes while the medicine is wearing off. Your medical team will monitor you closely throughout treatment. Tell your healthcare provider immediately if you experience severe difficulty breathing, prolonged muscle weakness, or signs of a severe allergic reaction after your procedure.

Do not receive this medicine if you have previously had a severe allergic reaction to cisatracurium or similar muscle relaxants. Before treatment, tell your doctor if you have myasthenia gravis, other nerve-muscle disorders, severe electrolyte imbalances, or a history of major burn injuries. Certain medicines, including some antibiotics, lithium, and medicines for seizures or heart conditions, may affect how this medicine works. If you are pregnant, breastfeeding, elderly, or have kidney or liver disease, your doctor will monitor your treatment carefully.

Uses of Cisblok 20mg Injection

This medicine is used in hospitals to provide controlled muscle relaxation during surgery and intensive care.

  • Skeletal muscle relaxation during surgery: Relaxes your muscles so surgeons can perform operations safely and accurately.
  • Tracheal intubation: Relaxes the muscles of the throat and airway, making it easier and safer for healthcare professionals to insert a breathing tube.
  • Mechanical ventilation support: Helps patients in the intensive care unit remain comfortable while breathing with a mechanical ventilator by preventing muscle resistance.

Key Benefits

This medicine provides reliable muscle relaxation during surgery and critical care.

  • Provides controlled muscle relaxation: Keeps the muscles relaxed throughout surgery, helping surgeons perform delicate procedures with greater precision and reducing unwanted movement.
  • Supports safe airway management: Makes inserting a breathing tube smoother and helps reduce strain on the airway during medical procedures.
  • Supports mechanical ventilation: Helps patients breathe comfortably with a ventilator by allowing the breathing machine to work effectively without muscle resistance.
  • Suitable for patients with kidney or liver disease: This medicine is broken down naturally in the body and does not depend mainly on the kidneys or liver for elimination, making its effects more predictable in many patients with kidney or liver impairment.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Cisblok 20mg Injection will be administered by a doctor or nurse in a healthcare facility.
  • Do not self-administer.

How Cisblok 20mg Injection Works

Cisblok 20mg Injection contains Cisatracurium. Cisatracurium belongs to a group of medicines called non-depolarising neuromuscular blockers. It works by blocking the action of acetylcholine, a natural chemical messenger that carries signals from nerves to muscles. This prevents the muscles from receiving the signal to contract, causing temporary muscle relaxation. The medicine is naturally broken down in the body through a process that does not rely mainly on the kidneys or liver, so its effects gradually wear off after the procedure is completed.
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Alcohol

Consult your doctor

It is unknown if alcohol interacts with Cisblok 20mg Injection. Please consult a doctor if you have any concerns.

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Pregnancy

Caution

If you are pregnant or planning a pregnancy, inform the doctor before receiving Cisblok 20mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

There is limited data on the use of Cisblok 20mg Injection during breastfeeding. Consult your healthcare provider to assess risks and benefits.

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Driving

Consult your doctor

There is limited data on the use of Cisblok 20mg Injection during driving. Consult your healthcare provider to assess risks and benefits.

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Liver

Consult your doctor

Please consult the doctor if you have any concerns regarding the usage of Cisblok 20mg Injection in patients with liver problems.

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Kidney

Consult your doctor

Please consult the doctor if you have any concerns regarding the usage of Cisblok 20mg Injection in patients with kidney problems.

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Children

Safe if prescribed

Cisblok 20mg Injection is safe for children over 1 month of age if prescribed by the doctor. Please consult your doctor if you have any concerns regarding its usage in children.

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Heart

Safe if prescribed

Cisblok 20mg Injection is generally considered safe for heart patients, but it should be used under medical supervision. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Cisblok 20mg Injection is generally considered safe for use in geriatric people when used as directed by the doctor, but it is crucial to take significant precautions because of sensitivities related to aging and the possibility of drug interactions.

What if I have taken an overdose of Cisblok 20mg Injection

An overdose is highly unlikely because this medicine is carefully measured and monitored by specialists. However, if too much is given, it may cause prolonged muscle weakness and severe breathing difficulties. Your healthcare team will support your breathing with a ventilator if needed and may give a medicine to reverse the muscle-relaxing effects.

Diet & Lifestyle Advise

  • Follow fasting instructions carefully: Do not eat or drink before your procedure unless your anaesthesia team tells you it is safe to do so. This helps reduce the risk of stomach contents entering your lungs during anaesthesia.
  • Rest after your procedure: Give your body enough time to recover and allow your muscles to regain their normal strength and coordination.
  • Stay well hydrated: Drink plenty of water after your procedure once your healthcare provider confirms that it is safe to do so.
  • Avoid driving or operating machinery: Do not drive, operate heavy machinery, or make important decisions for at least 24 hours after your procedure because the effects of anaesthesia and other medicines may temporarily affect your alertness and coordination.
     
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How Soon It Starts Working

The time required for Cisblok 20mg Injection to start to work: Cisblok 20mg Injection shows its action within 180 seconds approximately after administration. The time for which the effects of Cisblok 20mg Injection last: Cisblok 20mg Injection generally remains effective for about 40 minutes.

What if you forget to take Cisblok 20mg Injection

Since this medicine is given only in a controlled hospital setting for surgery or intensive care, missing a dose is extremely unlikely. Your healthcare team will manage the timing and administration of every dose.

Storage

•Store Cisblok 20mg Injection in a refrigerator between 2°C and 8°C.• Protect the medicine from light.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Receive this medicine only in a hospital: It should only be administered in a fully equipped healthcare facility where emergency breathing equipment and medicines to reverse its effects are immediately available.
  • Check the medicine before use: Your healthcare provider will inspect the vial to ensure the solution is clear, colourless to pale yellow, and free from visible particles before administration.
  • Tell your doctor about previous burns: A history of severe burn injuries can change how your body responds to this medicine and may affect the dose you need.
  • Inform your doctor about nerve-muscle disorders: Conditions such as myasthenia gravis or Eaton-Lambert syndrome can make you much more sensitive to this medicine and require careful dose adjustments.
  • Discuss pregnancy and breastfeeding: Tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding before receiving this medicine so the benefits and risks can be carefully assessed.

Drug-Drug Interactions

verifiedApollotooltip
  • Aminoglycoside, polymyxin, and tetracycline antibiotics (i.e. gentamicin, amikacin, polymyxin B, tetracycline): May increase the muscle-relaxing effects of Cisblok 20mg Injection, causing muscle weakness to last longer than expected.
  • Mood stabilisers and calcium channel blockers (i.e. lithium, amlodipine, diltiazem, verapamil): May prolong the effects of this medicine, requiring careful monitoring and dose adjustment.
  • Antiseizure medicines (i.e. phenytoin, carbamazepine): May reduce the duration of muscle relaxation, meaning additional doses may be needed during prolonged procedures.
CisatracuriumTobramycin
Severe
CisatracuriumColistin
Severe

Drug-Drug Interactions

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CisatracuriumTobramycin
Severe
How does the drug interact with Cisblok 20mg Injection 10ml:
Combining tobramycin together with Cisblok 20mg Injection 10ml can increase the neuromuscular blocking effects( disorder that effects nerves and muscles) of Cisblok 20mg Injection 10ml.

How to manage the interaction:
Although there is a possible interaction between Cisblok 20mg Injection 10ml and Tobramycin, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - having trouble breathing contact your doctor right away. Do not stop using any medications without a doctor's advice.
CisatracuriumColistin
Severe
How does the drug interact with Cisblok 20mg Injection 10ml:
Coadministration of Cisblok 20mg Injection 10ml with Colistin may increase the risk of side effects of Cisblok 20mg Injection 10ml.

How to manage the interaction:
Although there is a possible interaction of Cisblok 20mg Injection 10ml with Colistin, it can be taken if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, Slurred speech, Vertigo, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
CisatracuriumAmikacin
Severe
How does the drug interact with Cisblok 20mg Injection 10ml:
Co-administration of Amikacin with Cisblok 20mg Injection 10ml can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Cisblok 20mg Injection 10ml and Amikacin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
CisatracuriumBotulinum toxin
Severe
How does the drug interact with Cisblok 20mg Injection 10ml:
Using Botulinum Toxin with Cisblok 20mg Injection 10ml may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Botulinum toxin and Cisblok 20mg Injection 10ml, they can be taken together if prescribed by a doctor. However, if you experience muscle weakness or trouble breathing, swallowing, or speaking, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
CisatracuriumStreptomycin
Severe
How does the drug interact with Cisblok 20mg Injection 10ml:
Co-administration of Streptomycin with Cisblok 20mg Injection 10ml may increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Co-administration of Streptomycin with Cisblok 20mg Injection 10ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Cisblok 20mg Injection when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NEUROMUSCULAR BLOCKING AGENTS]

FAQs

Cisblok 20mg Injection is a neuromuscular blocking agent used to relax muscles during surgery, assist with tracheal intubation, and support muscle relaxation in intensive care settings.
Cisblok 20mg Injection contains Cisatracurium, which works by inhibiting acetylcholine from binding to the nicotinic receptors at the neuromuscular junction. This prevents muscle cell depolarization and causes muscular relaxation.
Yes, Cisblok 20mg Injection is safe for children over 1 month of age if prescribed by the doctor. However, it should only be administered under medical supervision.
Some people may experience reactions at the injection site, such as pain, redness, or swelling, but these typically resolve on their own. Seek medical advice if the reactions persist or worsen.
It is advised to consult a doctor before taking other medicines with Cisblok 20mg Injection to prevent any interactions. Let the doctor know if you are on treatment with other medicines, including herbal products.
The side effects of Cisblok 20mg Injection include flushing, slow heartbeat, low blood pressure, and bronchospasm. Seek medical care if any of the side effects bother you.
No. Cisblok 20mg Injection only relaxes your muscles. It does not make you sleep or relieve pain. It is always used together with anaesthetic and pain-relieving medicines during surgery so that you remain comfortable throughout the procedure. Your anaesthetist can explain your anaesthesia plan in more detail.
Yes. This medicine is often preferred for people with kidney or liver disease because it is mainly broken down naturally in the body rather than relying on these organs. However, your medical team will still monitor you closely throughout treatment.
No. You will usually receive a general anaesthetic or appropriate sedation before or at the same time as this medicine, so you should not be aware of the muscle relaxation during the procedure. Speak with your anaesthetist if you have concerns about what to expect.
Because this medicine is only administered in hospitals, trained healthcare professionals can recognise and treat allergic reactions immediately using emergency medicines and supportive care. Tell your doctor if you have previously had an allergic reaction to a muscle relaxant.
This medicine is used during pregnancy only when your doctor believes the expected benefits outweigh the possible risks to the unborn baby. Your healthcare team will carefully assess your condition before making this decision.
If necessary, your anaesthetist can give a medicine that reverses the muscle-relaxing effects, helping your muscles recover normal strength more quickly after surgery. If you have questions about your recovery, your healthcare team will be happy to explain the process.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - CIS0061

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