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compositionComposition:CISATRACURIUM-10MG
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CISATRA 10MG/5ML INJECTION is a non-depolarizing neuromuscular blocking agent used primarily to induce muscle relaxation during surgical procedures or in intensive care settings. It works by blocking the transmission of nerve impulses to the muscles, facilitating endotracheal intubation and improving surgical conditions. Some individuals may experience flushing, slow heartbeat, and low blood pressure.

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Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

CISATRACURIUM-10MG

Manufacturer/Marketer :

Themis Pharmaceutical Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About CISATRA 10MG/5ML INJECTION

CISATRA 10MG/5ML INJECTION is a prescription injection used to relax the body's muscles during surgery, certain medical procedures, or while you are receiving breathing support with a ventilator in an intensive care unit (ICU). It works by temporarily blocking the signals between your nerves and muscles, allowing your healthcare team to safely place a breathing tube, perform surgery, or provide mechanical ventilation.

This medicine is commonly used to provide muscle relaxation during surgery, make tracheal intubation (placement of a breathing tube) easier, and help patients breathe comfortably with a mechanical ventilator in the ICU. It relaxes only the muscles and does not provide pain relief or make you unconscious, so it is always used together with appropriate anaesthesia or sedation.

Because this medicine is given as an injection in a hospital, it is not used as a regular treatment at home. It is administered as a single injection or a continuous intravenous infusion by trained healthcare professionals only when needed for your procedure. Before surgery, you will usually be asked to avoid eating or drinking for a certain period as instructed by your anaesthesia team.

Some people may develop temporary side effects such as a slow heart rate, low blood pressure, flushing, or mild breathing changes while the medicine is wearing off. Your medical team will monitor you closely throughout treatment. Tell your healthcare provider immediately if you experience severe difficulty breathing, prolonged muscle weakness, or signs of a severe allergic reaction after your procedure.

Do not receive this medicine if you have previously had a severe allergic reaction to cisatracurium or similar muscle relaxants. Before treatment, tell your doctor if you have myasthenia gravis, other nerve-muscle disorders, severe electrolyte imbalances, or a history of major burn injuries. Certain medicines, including some antibiotics, lithium, and medicines for seizures or heart conditions, may affect how this medicine works. If you are pregnant, breastfeeding, elderly, or have kidney or liver disease, your doctor will monitor your treatment carefully.

Uses of CISATRA 10MG/5ML INJECTION

This medicine is used in hospitals to provide controlled muscle relaxation during surgery and intensive care.

  • Skeletal muscle relaxation during surgery: Relaxes your muscles so surgeons can perform operations safely and accurately.
  • Tracheal intubation: Relaxes the muscles of the throat and airway, making it easier and safer for healthcare professionals to insert a breathing tube.
  • Mechanical ventilation support: Helps patients in the intensive care unit remain comfortable while breathing with a mechanical ventilator by preventing muscle resistance.

Key Benefits

This medicine provides reliable muscle relaxation during surgery and critical care.

  • Provides controlled muscle relaxation: Keeps the muscles relaxed throughout surgery, helping surgeons perform delicate procedures with greater precision and reducing unwanted movement.
  • Supports safe airway management: Makes inserting a breathing tube smoother and helps reduce strain on the airway during medical procedures.
  • Supports mechanical ventilation: Helps patients breathe comfortably with a ventilator by allowing the breathing machine to work effectively without muscle resistance.
  • Suitable for patients with kidney or liver disease: This medicine is broken down naturally in the body and does not depend mainly on the kidneys or liver for elimination, making its effects more predictable in many patients with kidney or liver impairment.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • CISATRA 10MG/5ML INJECTION will be administered by a doctor or nurse in a healthcare facility.
  • Do not self-administer.

How CISATRA 10MG/5ML INJECTION Works

CISATRA 10MG/5ML INJECTION contains Cisatracurium. Cisatracurium belongs to a group of medicines called non-depolarising neuromuscular blockers. It works by blocking the action of acetylcholine, a natural chemical messenger that carries signals from nerves to muscles. This prevents the muscles from receiving the signal to contract, causing temporary muscle relaxation. The medicine is naturally broken down in the body through a process that does not rely mainly on the kidneys or liver, so its effects gradually wear off after the procedure is completed.
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Alcohol

Consult your doctor

It is unknown if alcohol interacts with CISATRA 10MG/5ML INJECTION. Please consult a doctor if you have any concerns.

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Pregnancy

Caution

If you are pregnant or planning a pregnancy, inform the doctor before receiving CISATRA 10MG/5ML INJECTION. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

There is limited data on the use of CISATRA 10MG/5ML INJECTION during breastfeeding. Consult your healthcare provider to assess risks and benefits.

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Driving

Consult your doctor

There is limited data on the use of CISATRA 10MG/5ML INJECTION during driving. Consult your healthcare provider to assess risks and benefits.

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Liver

Consult your doctor

Please consult the doctor if you have any concerns regarding the usage of CISATRA 10MG/5ML INJECTION in patients with liver problems.

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Kidney

Consult your doctor

Please consult the doctor if you have any concerns regarding the usage of CISATRA 10MG/5ML INJECTION in patients with kidney problems.

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Children

Safe if prescribed

CISATRA 10MG/5ML INJECTION is safe for children over 1 month of age if prescribed by the doctor. Please consult your doctor if you have any concerns regarding its usage in children.

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Heart

Safe if prescribed

CISATRA 10MG/5ML INJECTION is generally considered safe for heart patients, but it should be used under medical supervision. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

CISATRA 10MG/5ML INJECTION is generally considered safe for use in geriatric people when used as directed by the doctor, but it is crucial to take significant precautions because of sensitivities related to aging and the possibility of drug interactions.

What if I have taken an overdose of CISATRA 10MG/5ML INJECTION

An overdose is highly unlikely because this medicine is carefully measured and monitored by specialists. However, if too much is given, it may cause prolonged muscle weakness and severe breathing difficulties. Your healthcare team will support your breathing with a ventilator if needed and may give a medicine to reverse the muscle-relaxing effects.

Diet & Lifestyle Advise

  • Follow fasting instructions carefully: Do not eat or drink before your procedure unless your anaesthesia team tells you it is safe to do so. This helps reduce the risk of stomach contents entering your lungs during anaesthesia.
  • Rest after your procedure: Give your body enough time to recover and allow your muscles to regain their normal strength and coordination.
  • Stay well hydrated: Drink plenty of water after your procedure once your healthcare provider confirms that it is safe to do so.
  • Avoid driving or operating machinery: Do not drive, operate heavy machinery, or make important decisions for at least 24 hours after your procedure because the effects of anaesthesia and other medicines may temporarily affect your alertness and coordination.
     
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How Soon It Starts Working

The time required for CISATRA 10MG/5ML INJECTION to start to work: CISATRA 10MG/5ML INJECTION shows its action within 180 seconds approximately after administration. The time for which the effects of CISATRA 10MG/5ML INJECTION last: CISATRA 10MG/5ML INJECTION generally remains effective for about 40 minutes.

What if you forget to take CISATRA 10MG/5ML INJECTION

Since this medicine is given only in a controlled hospital setting for surgery or intensive care, missing a dose is extremely unlikely. Your healthcare team will manage the timing and administration of every dose.

Storage

•Store CISATRA 10MG/5ML INJECTION in a refrigerator between 2°C and 8°C.• Protect the medicine from light.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Receive this medicine only in a hospital: It should only be administered in a fully equipped healthcare facility where emergency breathing equipment and medicines to reverse its effects are immediately available.
  • Check the medicine before use: Your healthcare provider will inspect the vial to ensure the solution is clear, colourless to pale yellow, and free from visible particles before administration.
  • Tell your doctor about previous burns: A history of severe burn injuries can change how your body responds to this medicine and may affect the dose you need.
  • Inform your doctor about nerve-muscle disorders: Conditions such as myasthenia gravis or Eaton-Lambert syndrome can make you much more sensitive to this medicine and require careful dose adjustments.
  • Discuss pregnancy and breastfeeding: Tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding before receiving this medicine so the benefits and risks can be carefully assessed.

Drug-Drug Interactions

verifiedApollotooltip
  • Aminoglycoside, polymyxin, and tetracycline antibiotics (i.e. gentamicin, amikacin, polymyxin B, tetracycline): May increase the muscle-relaxing effects of CISATRA 10MG/5ML INJECTION, causing muscle weakness to last longer than expected.
  • Mood stabilisers and calcium channel blockers (i.e. lithium, amlodipine, diltiazem, verapamil): May prolong the effects of this medicine, requiring careful monitoring and dose adjustment.
  • Antiseizure medicines (i.e. phenytoin, carbamazepine): May reduce the duration of muscle relaxation, meaning additional doses may be needed during prolonged procedures.
CisatracuriumAmikacin
Severe
CisatracuriumBotulinum toxin
Severe

Drug-Drug Interactions

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CisatracuriumAmikacin
Severe
How does the drug interact with Cisatra 10mg/5ml Injection:
Co-administration of Amikacin with Cisatra 10mg/5ml Injection can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Cisatra 10mg/5ml Injection and Amikacin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
CisatracuriumBotulinum toxin
Severe
How does the drug interact with Cisatra 10mg/5ml Injection:
Using Botulinum Toxin with Cisatra 10mg/5ml Injection may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Botulinum toxin and Cisatra 10mg/5ml Injection, they can be taken together if prescribed by a doctor. However, if you experience muscle weakness or trouble breathing, swallowing, or speaking, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
CisatracuriumColistin
Severe
How does the drug interact with Cisatra 10mg/5ml Injection:
Coadministration of Cisatra 10mg/5ml Injection with Colistin may increase the risk of side effects of Cisatra 10mg/5ml Injection.

How to manage the interaction:
Although there is a possible interaction of Cisatra 10mg/5ml Injection with Colistin, it can be taken if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, Slurred speech, Vertigo, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
CisatracuriumTobramycin
Severe
How does the drug interact with Cisatra 10mg/5ml Injection:
Combining tobramycin together with Cisatra 10mg/5ml Injection can increase the neuromuscular blocking effects( disorder that effects nerves and muscles) of Cisatra 10mg/5ml Injection.

How to manage the interaction:
Although there is a possible interaction between Cisatra 10mg/5ml Injection and Tobramycin, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - having trouble breathing contact your doctor right away. Do not stop using any medications without a doctor's advice.
CisatracuriumStreptomycin
Severe
How does the drug interact with Cisatra 10mg/5ml Injection:
Co-administration of Streptomycin with Cisatra 10mg/5ml Injection may increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Co-administration of Streptomycin with Cisatra 10mg/5ml Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with CISATRA 10MG/5ML INJECTION when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NEUROMUSCULAR BLOCKING AGENTS]

FAQs

CISATRA 10MG/5ML INJECTION is a neuromuscular blocking agent used to relax muscles during surgery, assist with tracheal intubation, and support muscle relaxation in intensive care settings.
CISATRA 10MG/5ML INJECTION contains Cisatracurium, which works by inhibiting acetylcholine from binding to the nicotinic receptors at the neuromuscular junction. This prevents muscle cell depolarization and causes muscular relaxation.
Yes, CISATRA 10MG/5ML INJECTION is safe for children over 1 month of age if prescribed by the doctor. However, it should only be administered under medical supervision.
Some people may experience reactions at the injection site, such as pain, redness, or swelling, but these typically resolve on their own. Seek medical advice if the reactions persist or worsen.
It is advised to consult a doctor before taking other medicines with CISATRA 10MG/5ML INJECTION to prevent any interactions. Let the doctor know if you are on treatment with other medicines, including herbal products.
The side effects of CISATRA 10MG/5ML INJECTION include flushing, slow heartbeat, low blood pressure, and bronchospasm. Seek medical care if any of the side effects bother you.
No. CISATRA 10MG/5ML INJECTION only relaxes your muscles. It does not make you sleep or relieve pain. It is always used together with anaesthetic and pain-relieving medicines during surgery so that you remain comfortable throughout the procedure. Your anaesthetist can explain your anaesthesia plan in more detail.
Yes. This medicine is often preferred for people with kidney or liver disease because it is mainly broken down naturally in the body rather than relying on these organs. However, your medical team will still monitor you closely throughout treatment.
No. You will usually receive a general anaesthetic or appropriate sedation before or at the same time as this medicine, so you should not be aware of the muscle relaxation during the procedure. Speak with your anaesthetist if you have concerns about what to expect.
Because this medicine is only administered in hospitals, trained healthcare professionals can recognise and treat allergic reactions immediately using emergency medicines and supportive care. Tell your doctor if you have previously had an allergic reaction to a muscle relaxant.
This medicine is used during pregnancy only when your doctor believes the expected benefits outweigh the possible risks to the unborn baby. Your healthcare team will carefully assess your condition before making this decision.
If necessary, your anaesthetist can give a medicine that reverses the muscle-relaxing effects, helping your muscles recover normal strength more quickly after surgery. If you have questions about your recovery, your healthcare team will be happy to explain the process.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Other Info - CIS0056
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