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Ciplox-D Eye/Ear Drops contains a combination of three medicines used to treat bacterial ear and eye infections such as post-operative inflammatory conditions of the eyes, acute otitis media, and acute otitis externa. This medicine stops the growth of bacteria by inhibiting the DNA-gyrase enzyme and thereby helps reduce bacterial eye infections. This medicine is not effective for treating viral infections. Sometimes, you may experience certain common side effects, such as eye discomfort, irritation, eye/ear pain, and stinging sensation.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Eye/Ear

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Ciplox-D Eye/Ear Drops

Ciplox-D Eye/Ear Drops is used to treat bacterial eye infections, post-operative inflammatory conditions of the eyes, acute otitis media (middle ear infections) and acute otitis externa (inflammation of the ear canal). Bacterial eye infection is associated with the inflammation or infection of the conjunctiva (white part of the eye) and the inner eyelid. An ear infection occurs when the bacteria affect the middle or outer ear, leading to pain and inflammation.
 
Ciplox-D Eye/Ear Drops is a combination of three drugs: Ciprofloxacin, Dexamethasone, and Benzalkonium chloride. Ciprofloxacin kills the infection-causing bacteria by inhibiting the synthesis of enzymes necessary for the survival of bacteria. Dexamethasone blocks the chemical messengers that cause swelling, itching, and redness. Benzalkonium chloride acts as a preservative. Thereby, Ciplox-D Eye/Ear Drops helps in treating bacterial infections of the eye and ear.
 
You are advised to use Ciplox-D Eye/Ear Drops for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Ciplox-D Eye/Ear Drops may cause common side effects such as discomfort, irritation, stinging sensation, and redness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Talk to your doctor if the irritation persists despite using Ciplox-D Eye/Ear Drops for a week or if it worsens. Consult your doctor if you are pregnant or breastfeeding. Ciplox-D Eye/Ear Drops should be used in children only if prescribed by the doctor. Do not touch the tip of the dropper, as it may contaminate the contents. Keep your doctor informed regarding your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of Ciplox-D Eye/Ear Drops

Ciplox-D Eye/Ear Drops is used to treat bacterial infections and reduce inflammation in the eyes and ears. The detailed uses of Ciplox-D Eye/Ear Drops are as follows:

  • Bacterial eye infections: Ciplox-D Eye/Ear Drops treats bacterial infections of the eye and prevents further complications.
  • Treatment of acute otitis media: Ciplox-D Eye/Ear Drops is effective in treating bacterial middle ear infections, reducing pain and inflammation.
  • Treatment of acute otitis externa: Ciplox-D Eye/Ear Drops reduces inflammation and infection of the external ear canal.
  • Relief from infection-related discomfort: Ciplox-D Eye/Ear Drops relieves bacterial infection symptoms such as pain, redness, swelling, and itching.

Key Benefits

Ciplox-D Eye/Ear Drops is a combination of three drugs: Ciprofloxacin, Dexamethasone, and Benzalkonium chloride. Ciplox-D Eye/Ear Drops is used to treat bacterial eye infections, post-operative inflammatory conditions of the eyes, acute otitis media (middle ear infections) and acute otitis externa (inflammation of the ear canal). Dexamethasone is a corticosteroid that blocks the chemical messengers that cause swelling, itching, and redness. Ciprofloxacin is an anti-bacterial agent that kills bacteria by preventing the synthesis of essential proteins required for the survival of the bacteria. Benzalkonium chloride acts as a preservative. Together, Ciplox-D Eye/Ear Drops helps in treating bacterial infections of the eye/ear.

Side effects of Ciplox-D Eye/Ear Drops 10 ml
  • Your doctor may recommend lubricating eye drops to reduce irritation and dryness in the eyes, helping to soothe the cornea and prevent additional discomfort.
  • Your doctor may suggest phototherapeutic keratectomy (PTK), a surgical technique that employs ultraviolet radiation to clear corneal deposits and improve vision.
  • Wear protective eyewear like goggles or sunglasses to avoid further eye injuries.
  • Avoid rubbing your eyes because it can worsen the condition.
  • Keep your eyes clean by rinsing them gently with artificial tears or saline solution.
  • Quit smoking, as it can worsen corneal deposits.
  • Antioxidant supplements such as vitamins C and E may help protect the cornea from damage.
  • Inform your doctor if you notice any changes in vision, such as blurred, double, or lost vision.
  • Eat a healthy, well-balanced diet full of vitamins, minerals, and omega-3 fatty acids to help maintain eye health.
  • Wear UV-protecting sunglasses when you are outside or in bright light.
  • Avoid touching or rubbing your eyes it may increase irritation.
  • Seek medical care if you are experiencing extreme eye pain or discomfort.
  • Stay hydrated by drinking plenty of water.
  • Get plenty of rest to help your eyes recover.
  • Eat a balanced diet low in fat and rich in fruits, vegetables, and whole grains.
  • Limit spicy and seasoned foods that can irritate your eyes.
  • Avoid seafood, which can trigger allergies or infections that worsen red eye symptoms.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Ciplox-D Eye/Ear Drops is intended for use in the eyes and ears only.
  • For eye use: Tilt your head back and pull your lower eyelid downwards and outwards; instil the drops into the eye pouch.
  • For ear use: Tilt your head to the side and gently instil drops inside the ear. Keep your head tilted for a minute to let the drops soak in.
  • Do not touch the dropper with your bare hands when administering the drops to prevent contamination.

How Ciplox-D Eye/Ear Drops Works

Ciplox-D Eye/Ear Drops is a combination of three drugs: Ciprofloxacin, Dexamethasone, and Benzalkonium chloride. Ciprofloxacin kills the infection-causing bacteria by inhibiting the synthesis of enzymes necessary for the survival of bacteria. Dexamethasone blocks the chemical messengers that cause swelling, itching, and redness. Benzalkonium chloride acts as a preservative. Thereby, Ciplox-D Eye/Ear Drops helps in treating bacterial infections of the eye and ear.
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Alcohol

Caution

It is not known whether Ciplox-D Eye/Ear Drops interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will decide whether Ciplox-D Eye/Ear Drops can be used by breastfeeding mothers or not.

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Driving

Caution

Ciplox-D Eye/Ear Drops may temporarily blur your vision when instilled in the eyes. So, avoid driving or operating machinery until your vision is clear.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Ciplox-D Eye/Ear Drops in patients with liver impairment.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Ciplox-D Eye/Ear Drops in patients with kidney impairment.

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Children

Caution

Ciplox-D Eye/Ear Drops should be used in children only if prescribed by the doctor.

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Heart

Consult your doctor

Inform your doctor if you have a history of heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Ciplox-D Eye/Ear Drops should be used in elderly patients only if prescribed by a doctor. If you have any concerns about using Ciplox-D Eye/Ear Drops in older adults, please consult your doctor.

What if I have taken an overdose of Ciplox-D Eye/Ear Drops

Though it is unlikely to cause any harm if you have overdosed, it is advised not to exceed the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Diet & Lifestyle Advise

Eye infections: 

  • Wash your hands regularly. Avoid touching the eyes with dirty hands. 

  • Avoid rubbing the eyes.

  • Avoid sharing eye makeup such as eyeliner, mascara or kohl.

  • Always use clean towels or tissues to wipe your eyes and face.

  • Regularly wash and change the pillowcases.

  • If you wear contact lens: Clean and replace contact lens more often. Never share contact lens. Always remember to wash your hands before inserting and after removing the contact lens. 

  • Avoid staring at digital screens for longer durations. Rest your eyes for every 20 minutes.

  • Blink regularly as it helps in the spread of hydrating substances such as mucus and tears across the eyes.

 

Ear infections: 

  • Include fruits, vegetables, high-quality proteins and whole wheat grains in your diet to strengthen the immune system.

  • Avoid consuming foods that you are allergic to as it can cause the body to produce excess mucus leading to inflammation.

  • Avoid getting things like shampoo, soap, and water into the ear, as it can cause itching.

  • Do not poke or scratch the ear, as it can cause damage to the ear canal, leading to inflammation. The inflamed skin can be infected by bacteria or fungi, which can cause infections in the ear.

  • Stay healthy as immunity prevents infections.

Have a query?

How Soon It Starts Working

The time required for Ciplox-D Eye/Ear Drops to start to work: The effect of Ciplox-D Eye/Ear Drops begins to take action within 1 to 3 hours of administration. The time for which the effects of Ciplox-D Eye/Ear Drops last: Ciplox-D Eye/Ear Drops effect lasts for 24 hours.

What if you forget to take Ciplox-D Eye/Ear Drops

If you miss a dose, use it as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the next dose at the regular time.

Storage

• Store in a cool and dry place away from sunlight. • Keep Ciplox-D Eye/Ear Drops out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Do not use Ciplox-D Eye/Ear Drops if you are allergic to any of its contents. Avoid using Ciplox-D Eye/Ear Drops if you have tuberculosis, damaged cornea, ulceration, lesions with incomplete formation of the covering tissue, increased intraocular pressure, allergy to steroids, viral ear infections, herpes simplex, fungal or parasitic ear infection. Inform your doctor if you have high closed-angle glaucoma, high blood pressure, ocular hypertension, diabetes, eye infection or injury, hyperthyroidism, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Ciplox-D Eye/Ear Drops should be used in children only if prescribed by the doctor.

Drug-Drug Interactions

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Drug-Drug Interactions: Inform your doctor if you are taking anti-viral drugs (ritonavir, cobicistat)

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have tuberculosis, damaged cornea, ulceration, lesions with incomplete formation of the covering tissue, increased intraocular pressure, allergy to steroids, viral ear infections, herpes simplex, fungal or parasitic ear infection.

Drug-Drug Interactions

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How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Taking Ciplox-D Eye/Ear Drops 10 ml with amiodarone increases the risk of an irregular heart rhythm, and reduces the effects of Dexamethasone. Additionally, it causes tendinitis, which is an inflammation of the tissue connecting muscle to bone, and tendon rupture, which is an injury to the soft tissues that connect muscles and joints.

How to manage the interaction:
Taking Ciplox-D Eye/Ear Drops 10 ml with amiodarone is not recommended, as it can lead to an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath, pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Taking Ciplox-D Eye/Ear Drops 10 ml with Ranolazine reduces the effects of Dexamethasone. Additionally, it can cause tendinitis, which is an inflammation of the tissue connecting muscle to bone, and tendon rupture, which is an injury to the soft tissues that connect muscles and joints.

How to manage the interaction:
Co-administration of Ciplox-D Eye/Ear Drops 10 ml with Ranolazine is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Taking Ciplox-D Eye/Ear Drops 10 ml with bempedoic acid may cause tendinitis (a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Although there is an interaction, Ciplox-D Eye/Ear Drops 10 ml can be taken with bempedoic acid if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Using Ciplox-D Eye/Ear Drops 10 ml with Voclosporin can increase can speed up the metabolism of voclosporin leading to its reduced effectiveness.

How to manage the interaction:
Although taking Ciplox-D Eye/Ear Drops 10 ml together with Voclosporin can cause an interaction, it can be taken if a doctor has suggested it. If you experience any unusual symptoms, it's important to contact the doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Co-administration of Ciplox-D Eye/Ear Drops 10 ml together with deflazacort can cause tendinitis (a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture (injuries to the soft tissues that connect muscles and joints), can also reduce the blood levels of deflazacort making it less effective.

How to manage the interaction:
Although using Ciplox-D Eye/Ear Drops 10 ml and Deflazacort together can possibly result in an interaction, they can be taken together if advised by your doctor. However, consult a doctor if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Co-administration of Ciplox-D Eye/Ear Drops 10 ml together with theophylline can cause tendinitis (a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture (injuries to the soft tissues that connect muscles and joints), it can also increase the blood levels of theophylline leading to side effects.

How to manage the interaction:
Although taking Ciplox-D Eye/Ear Drops 10 ml together with theophylline can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, diarrhoea, lack of appetite, headache, tremors (shaking of hands & legs), confusion, restlessness, sleeplessness, seizures(fits), irregular heartbeat, pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Co-administration of Ciplox-D Eye/Ear Drops 10 ml together with Oxycodone can cause tendinitis (a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture (injuries to the soft tissues that connect muscles and joints), it can also alter the blood levels of Oxycodone leading to side effects.

How to manage the interaction:
Although taking Ciplox-D Eye/Ear Drops 10 ml together with Oxycodone can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience, pain, or swelling of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb, dizziness, confusion, and/or shallow or difficult breathing, watery eyes, sneezing, yawning, excessive sweating, fever, chills, flushing, restlessness, anxiety, body aches, involuntary twitching and kicking, abdominal cramping, consult a doctor. Avoid tasks that require mental attention, such as operating machinery or driving, and proceed with caution while rising from a seated or lying down posture. Do not stop using any medications without consulting a doctor.
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Taking Ciplox-D Eye/Ear Drops 10 ml with bosutinib may cause tendinitis (a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
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How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Taking Ciplox-D Eye/Ear Drops 10 ml with insulin degludec can result in hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar), as well as tendinitis (inflammation of the tissue that connects muscle to bone) and tendon rupture (damage to the soft tissues that connect muscles and joints).

How to manage the interaction:
There could be a possible interaction between Ciplox-D Eye/Ear Drops 10 ml and insulin degludec but can be taken if prescribed by a doctor. However, consult a doctor immediately if you experience headache, dizziness, confusion, tremors, nausea, hunger, weakness, excessive sweating, rapid heartbeat, increased thirst, increased hunger, increased urination, pain, swelling of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb. Do not stop using any medications without consulting a doctor.
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Taking Ciplox-D Eye/Ear Drops 10 ml with mifepristone increases the risk of an irregular heart rhythm, and reduces the levels of Dexamethasone, which may make Dexamethasone less effective in treating your condition. Additionally, it causes tendinitis, which is an inflammation of the tissue connecting muscle to bone, and tendon rupture, which is an injury to the soft tissues that connect muscles and joints.

How to manage the interaction:
Co-administration of Ciplox-D Eye/Ear Drops 10 ml with mifepristone can cause an interaction. However, they can be taken together if prescribed by the doctor. However, if you experience, pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb, dizziness, shortness of breath, heart palpitations, muscle weakness, muscle cramps, numbness or tingling, and/or swelling in the legs or feet, consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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BENZALKONIUM CHLORIDE-0.01%W/V+CIPROFLOXACIN-0.3%W/V+DEXAMETHASONE-0.1%W/VCalcium rich foods, Caffeine containing foods/drinks
Moderate

Drug-Food Interactions

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BENZALKONIUM CHLORIDE-0.01%W/V+CIPROFLOXACIN-0.3%W/V+DEXAMETHASONE-0.1%W/VCalcium rich foods, Caffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt, Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Using caffeine together with ciprofloxacin may increase the effects of caffeine. Taking dairy products such as milk, yogurt, or calcium-fortified foods can make the medication less effective. Avoid taking caffeine with ciprofloxacin, as it causes effects. Contact your doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate. Avoid taking milk, yogurt, or calcium-fortified foods. You could interrupt the feeding for 1 hour before and 2 hours after the ciprofloxacin dose. Do not stop using any medications without talking to your doctor.

Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Ciplox-D Eye/Ear Drops is used to treat bacterial eye infections, post-operative inflammatory conditions of the eyes, acute otitis media (middle ear infections) and acute otitis externa (inflammation of the ear canal).

Ciplox-D Eye/Ear Drops kills the bacteria by preventing the synthesis of essential proteins required for survival of the bacteria. It also blocks the synthesis of chemical messengers that cause irritation. Thereby treats bacterial infections of the eye/ear.

Do not stop using Ciplox-D Eye/Ear Drops on your own. To treat your condition effectually, continue using Ciplox-D Eye/Ear Drops for as long as your doctor has prescribed it. Consult the doctor if the irritation persists or worsens.

Ciplox-D Eye/Ear Drops can be used with other eye/ear medications if prescribed by the doctor. However, maintain a gap of 5-10minutes between Ciplox-D Eye/Ear Drops and other eye/ear medications.

Do not use Ciplox-D Eye/Ear Drops for longer durations unless prescribed as it may lead to other infections. Consult your doctor if your condition worsens or does not improve despite using Ciplox-D Eye/Ear Drops for a week.

If you're taking ciprofloxacin for an infection, you should start feeling better within a few days. However, this depends on the type of infection. If you don't see improvement after 2-3 days or if your symptoms worsen, consult the doctor. They can assess your progress and provide further guidance.

Ciplox-D Eye/Ear Drops should be stored in a cool and dry place away from sunlight. Dispose of the Ciplox-D Eye/Ear Drops and packaging responsibly. Do not flush the medication down the toilet or pour it down the drain.

Eye drops: Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes. Ear drops: Lie down with the affected ear facing upwards. Hold the dropper over the ear and instill the prescribed number of drops into the ear.

Ciplox-D Eye/Ear Drops contains ciprofloxacin, dexamethasone, and benzalkonium chloride. It is used to treat bacterial eye infections, post-operative inflammatory conditions of the eyes, acute otitis media (middle ear infections), and acute otitis externa (inflammation of the ear canal).

The common side effects of Ciplox-D Eye/Ear Drops may include discomfort, irritation, stinging sensation, and redness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Follow your doctor's advice and take the right amount of medicine. Be aware of side effects and take care of yourself. If you're pregnant while on treatment, inform your doctor immediately. Don't take other medications unless instructed by the doctor. Limit or intake of alcohol to avoid unpleasant side effects. Ciplox-D Eye/Ear Drops may temporarily blur your vision when instilled in the eyes. So, avoid driving or operating machinery until your vision is clear. Always follow the doctor's instructions.

Ciplox-D Eye/Ear Drops should be used in children only if prescribed by the doctor. Please consult your doctor before using it in children.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - CIP0024
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