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  3. CIDNAVIR 75 Injection 1's

CIDNAVIR 75 Injection 1's, Pack of 1 INJECTION
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

CIDNAVIR 75 Injection 1's is used in the treatment of cytomegalovirus (CMV) retinitis. It contains Cidofovir, which works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis. It works by slowing the growth of the cytomegalovirus. Thus, it helps treat Cytomegalovirus (CMV) retinitis. This medicine is contraindicated in patients with renal insufficiency and patients who cannot receive probenecid or other sulfa-containing products. This medicine should not be used for conditions other than CMV retinitis.

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Composition :

CIDOFOVIR-75MG/ML

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About CIDNAVIR 75 Injection 1's

CIDNAVIR 75 Injection 1's is an antiviral medicine used in the treatment of cytomegalovirus (CMV) retinitis. Cytomegalovirus (CMV) retinitis is a viral infection that affects the retina of the eye caused by a virus called Cytomegalovirus (CMV), especially in AIDS patients. It is a serious infection that can lead to blindness. CIDNAVIR 75 Injection 1's is used in combination with oral probenecid.

CIDNAVIR 75 Injection 1's contains Cidofovir, which works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis. It works by slowing the growth of the cytomegalovirus. Thus, it helps treat Cytomegalovirus (CMV) retinitis.

CIDNAVIR 75 Injection 1's may cause certain side effects such as nausea, vomiting, headache, hair loss, rash, weakness, fever, inflammation of the eye, shortness of breath, diarrhoea, chills, and pain at the injection site. These side effects may not occur in every patient using this medication and gradually resolve over time. If the side effects persist longer or worsen, please inform your doctor. A healthcare professional will administer CIDNAVIR 75 Injection 1's; hence, do not self-administer.

CIDNAVIR 75 Injection 1's should be avoided if you are allergic to it. This medicine is contraindicated in patients with renal insufficiency and patients who cannot receive probenecid or other sulfa-containing products. This medicine should not be used for conditions other than CMV retinitis. Let your doctor know about your complete medical and medication history to rule out any interactions. Inform your doctor if you have a weakened immune system, an electrolyte imbalance, diabetes, and liver or kidney diseases before starting the use of CIDNAVIR 75 Injection 1's. CIDNAVIR 75 Injection 1's is not recommended for use in pregnant and breastfeeding women.

Uses of CIDNAVIR 75 Injection 1's

CIDNAVIR 75 Injection 1's is used in the treatment of Cytomegalovirus (CMV) retinitis. The detailed use of CIDNAVIR 75 Injection 1's is as follows:

  • Cytomegalovirus (CMV) Retinitis in AIDS Patients: CIDNAVIR 75 Injection 1's helps slow the progression of CMV-related vision loss in people with AIDS.

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Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • CIDNAVIR 75 Injection 1's will be administered by a nurse or doctor.
  • Do not self-administer.

Medicinal Benefits

CIDNAVIR 75 Injection 1's treats viral infection of the eye caused by Cytomegalovirus (CMV) retinitis. CIDNAVIR 75 Injection 1's consists of Cidofovir, which works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis. It helps kill the virus and eventually stop the growth of the cytomegalovirus. Thus, helps to treat Cytomegalovirus (CMV) retinitis. This medicine is only used in treating CMV retinitis but is not used for other conditions. It does not help in treating HIV infection.

How CIDNAVIR 75 Injection 1's Works

CIDNAVIR 75 Injection 1's contains Cidofovir, which works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis. It works by slowing the growth of the cytomegalovirus. Thus, it helps treat Cytomegalovirus (CMV) retinitis.

Storage

• Store in a cool and dry place away from sunlight.• Keep CIDNAVIR 75 Injection 1's out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of CIDNAVIR 75 Injection
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Drink adequate water to stay hydrated and support kidney function.
  • Limit sodium intake and avoid processed foods to reduce blood pressure.
  • Consume moderate amounts of high-quality protein from sources like lean meats, fish, and plant-based options.
  • Restrict potassium-rich foods and control phosphorus intake to minimize kidney strain.
  • Include antioxidant-rich foods like fruits, vegetables, and omega-3 fatty acids in your diet.
  • Avoid consuming processed and high-sugar foods that can worsen kidney damage.
  • Limit alcohol consumption and caffeine intake to reduce kidney stress.
  • Quit smoking to significantly lower the risk of kidney damage.
  • Engage in regular exercise to control weight, improve circulation, and lower blood pressure.
  • Consider taking nutritional supplements like omega-3 fatty acids, vitamin D, and antioxidants under medical guidance.
  • Regularly schedule medical checkups to monitor kidney function and adjust your plan as needed.
  • Collaborate with a healthcare provider to develop a personalized diet and lifestyle plan tailored to your needs.
  • Low bicarbonate levels can lead to more acid buildup in your blood, so your doctor may administer sodium bicarbonate through an IV to help balance it.
  • Drink lots of fluids or water to reduce acid load in your blood, and make sure your urine is clear or light yellow.
  • Limit alcohol intake, as it can dehydrate you and increase acid buildup.
  • If you are diabetic, keep your blood sugar levels in a healthy range.
  • Eat high-alkaline foods, like fruits, nuts, legumes, and vegetables.
  • Avoid foods that can cause your body to produce more acids, including eggs, meats, cheese, and grains.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of CIDNAVIR 75 Injection 1's

As CIDNAVIR 75 Injection 1's is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of CIDNAVIR 75 Injection 1's may cause a change in the amount of urine.

Drug Warnings

CIDNAVIR 75 Injection 1's should be avoided if you are allergic to it. Let your doctor know about your medical history and medication history to rule out any interactions. This medicine is contraindicated in patients with renal insufficiency, patients who cannot receive probenecid or other sulfa-containing products, and the use of CIDNAVIR 75 Injection 1's in conditions other than CMV retinitis. Inform your doctor if you have a weakened immune system, an electrolyte imbalance, diabetes, and liver or kidney diseases before starting CIDNAVIR 75 Injection 1's. CIDNAVIR 75 Injection 1's is not recommended for use in pregnant and breastfeeding women. Hence, inform your doctor before starting CIDNAVIR 75 Injection 1's.  CIDNAVIR 75 Injection 1's may cause nephrotoxicity, haematological toxicity, decreased intraocular pressure, and metabolic acidosis in some patients. Hence, patients should be monitored carefully for any changes during the treatment. CIDNAVIR 75 Injection 1's is not recommended for use in children below 16 years of age as the safety and efficacy are not established. Avoid driving and operating machines, as it can cause fatigue and dizziness.

Drug-Drug Interactions

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CidofovirOlsalazine
Critical
CidofovirLutetium (177lu) oxodotreotide
Critical

Drug-Drug Interactions

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CidofovirOlsalazine
Critical
How does the drug interact with CIDNAVIR 75 Injection:
Co-administration of CIDNAVIR 75 Injection with Olsalazine can increase the risk of kidney problems.

How to manage the interaction:
Taking Olsalazine with CIDNAVIR 75 Injection is not recommended, please consult your doctor before taking it. but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
CidofovirLutetium (177lu) oxodotreotide
Critical
How does the drug interact with CIDNAVIR 75 Injection:
Co-administration of Lutetium (177lu) oxodotreotide may increase the risk of kidney problems.

How to manage the interaction:
Taking Lutetium (177lu) oxodotreotide with CIDNAVIR 75 Injection is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to a doctor.
CidofovirNaproxen
Critical
How does the drug interact with CIDNAVIR 75 Injection:
Taking CIDNAVIR 75 Injection with naproxen may increase the risk or severity of kidney problems

How to manage the interaction:
Taking Naproxen with CIDNAVIR 75 Injection is generally avoided as it can possibly result in an interaction. You should seek immediate medical attention if you develop signs and symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
CidofovirMesalazine
Critical
How does the drug interact with CIDNAVIR 75 Injection:
Co-administration of Mesalazine with CIDNAVIR 75 Injection can increase the risk of kidney problems.

How to manage the interaction:
Taking Mesalazine with CIDNAVIR 75 Injection is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
CidofovirFenoprofen
Critical
How does the drug interact with CIDNAVIR 75 Injection:
Co-administration of CIDNAVIR 75 Injection with Fenoprofen can increase the risk of kidney problems

How to manage the interaction:
Taking Fenoprofen with CIDNAVIR 75 Injection is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
CidofovirTobramycin
Critical
How does the drug interact with CIDNAVIR 75 Injection:
Coadministration of CIDNAVIR 75 Injection with Tobramycin can cause kidney problems.

How to manage the interaction:
Taking Tobramycin with CIDNAVIR 75 Injection is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting a doctor.
CidofovirValganciclovir
Critical
How does the drug interact with CIDNAVIR 75 Injection:
Taking CIDNAVIR 75 Injection with valganciclovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Valganciclovir with CIDNAVIR 75 Injection is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
CidofovirIndometacin
Critical
How does the drug interact with CIDNAVIR 75 Injection:
Co-administration of Indomethacin with CIDNAVIR 75 Injection can increase the risk of kidney problems.

How to manage the interaction:
Taking Indometacin with CIDNAVIR 75 Injection is not recommended as it can lead to an interaction, it can be used if prescribed by a doctor. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, shortness of breath, cramping in the muscles, weakness, confusion, and irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
CidofovirAciclovir
Critical
How does the drug interact with CIDNAVIR 75 Injection:
Co-administration of CIDNAVIR 75 Injection with Acyclovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Aciclovir with CIDNAVIR 75 Injection is not recommended, please consult your doctor before taking it. You should consult a doctor if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, weakness, and palpitations. Do not stop using any medications without talking to a doctor.
CidofovirGanciclovir
Critical
How does the drug interact with CIDNAVIR 75 Injection:
Coadministration of CIDNAVIR 75 Injection with ganciclovir can increase the risk of kidney problems.

How to manage the interaction:
Although there is a interaction between Ganciclovir and CIDNAVIR 75 Injection hence it is not recommended to be taken together, but it can be taken only if advised by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • Try to drink plenty of water to keep your body hydrated.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

CIDNAVIR 75 Injection 1's Substitute

Substitutes safety advice
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Alcohol

Consult your doctor

There is limited information on how alcohol consumption affects CIDNAVIR 75 Injection 1's. Please consult your doctor.

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Pregnancy

Unsafe

CIDNAVIR 75 Injection 1's may cause fetal toxicity and impairment of fertility in males and females. Hence, inform your doctor if you are pregnant before receiving CIDNAVIR 75 Injection 1's.

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Breast Feeding

Unsafe

CIDNAVIR 75 Injection 1's is not recommended for use in nursing mothers as it can cause serious side effects to newborn infants. Hence, inform your doctor if you are breastfeeding.

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Driving

Unsafe

CIDNAVIR 75 Injection 1's may cause fatigue and drowsiness. Hence, do not drive or operate machinery that requires mental alertness until you are not alert.

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Liver

Caution

Inform your doctor if you have any history of liver diseases or hepatic impairment before receiving CIDNAVIR 75 Injection 1's. Your doctor will advise this medicine only if the benefits outweigh the risks.

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Kidney

Caution

CIDNAVIR 75 Injection 1's is known to cause kidney damage. Hence, inform your doctor if you have any history of kidney problems before receiving CIDNAVIR 75 Injection 1's. This medicine is contraindicated in patients with severe renal disease or renal insufficiency.

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Children

Unsafe

The use of CIDNAVIR 75 Injection 1's is not recommended for children below 18 years of age as the safety and efficacy data are not established.

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Heart

CIDNAVIR 75 Injection 1's should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using CIDNAVIR 75 Injection 1's.

bannner image

Geriatrics

Caution

CIDNAVIR 75 Injection 1's should be used with caution in geriatric patients due to increased risk of age-related side effects. Therefore, please consult your doctor before giving CIDNAVIR 75 Injection 1's to elderly individuals.

FAQs

CIDNAVIR 75 Injection 1's is used to treat Cytomegalovirus (CMV) retinitis.

CIDNAVIR 75 Injection 1's works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis.

No,CIDNAVIR 75 Injection 1's will be administered by the trained healthcare professional. Do not self-administer it.

Inform your doctor if you are pregnant or a nursing mother before starting treatment with CIDNAVIR 75 Injection 1's. Maintain caution if you have kidney, liver, or blood disorders, a weakened immune system, diabetes, or an electrolyte imbalance, as it may worsen your condition. Your doctor will administer CIDNAVIR 75 Injection 1's only when the benefits outweigh the risks.

Country of origin

India

Manufacturer/Marketer address

A €“ 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
Other Info - CID0052

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Keep Refrigerated. Do not freeze.

Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 18, 2025 | 11:51 AM IST

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Reference

  1. https://www.ema.europa.eu/en/documents/product-information/vistide-epar-product-information_en.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/1999/020638s003lbl.pdf
  3. https://go.drugbank.com/drugs/DB00369
  4. https://reference.medscape.com/drug/cidofovir-342606
  5. https://medlineplus.gov/druginfo/meds/a696037.html
  6. https://www.drugs.com/mtm/cidofovir.html

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