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compositionComposition:CEFDINIR-300MG
prescription
Prescription Medicine
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Cefrine 300 mg Capsule is used to treat bacterial infections. It contains Cefdinir, which works by interfering with the formation of the bacterial cell wall and killing the bacteria. In some cases, this medicine may cause side effects such as diarrhoea, nausea, stomach pain, vomiting, rash, and headache. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFDINIR-300MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Cefrine 300 mg Capsule

Cefrine 300 mg Capsule is an oral antibiotic used to treat a variety of bacterial infections. It is prescribed for medical conditions affecting the lungs, sinuses, throat, and skin. This medication specifically targets and eliminates the harmful bacteria causing these illnesses.

Your doctor will typically advise you to take Cefrine 300 mg Capsule once or twice daily, and it is crucial to take it consistently at the same times each day. You can take this medication with or without food, though taking it with a meal can help if you experience stomach upset. Getting plenty of rest, staying hydrated, and eating a balanced diet will further support your recovery while using this medicine.

Some people may experience mild side effects, such as loose stools, nausea, or headaches, which usually go away as your body adjusts. However, if you experience severe diarrhoea, intense stomach pain, or signs of an allergic reaction, you must contact your doctor immediately. Do not ignore these serious symptoms, as they require prompt medical evaluation.

Before starting this medicine, talk to your doctor if you have kidney problems or a history of bowel inflammation like colitis. Do not take this if you have had a severe allergic reaction to cephalosporin antibiotics or penicillins. Your healthcare provider will help determine if this is the safest treatment option for your condition.

Certain medications, like iron supplements and antacids containing magnesium or aluminium, can prevent your body from absorbing Cefrine 300 mg Capsule properly if taken at the same time. If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist to ensure this medicine is appropriate for you.

Uses of Cefrine 300 mg Capsule

Your doctor may prescribe Cefrine 300 mg Capsule to treat several types of bacterial infections, including:

  • Pneumonia and Bronchitis: It treats these lower respiratory tract infections by stopping the growth of bacteria in the lungs and airways.
  • Sinusitis and Tonsillitis: It helps clear painful infections of the sinuses and throat, reducing swelling and discomfort.
  • Skin Infections: It resolves uncomplicated bacterial skin infections, reducing redness, swelling, and pain.
  • Middle Ear Infections: It clears painful ear infections by targeting the bacteria trapped in the middle ear space.
     

Key Benefits

Cefrine 300 mg Capsule helps treat bacterial infections by stopping the growth of the bacteria causing the illness. As the infection clears, it relieves symptoms, supports recovery, and helps prevent infection-related complications.

  • Helps Clear Bacterial Infections: By preventing bacteria from multiplying, Cefrine 300 mg Capsule helps your body's immune system eliminate the infection and promotes faster recovery.
  • Relieves Infection Symptoms: As the bacteria are cleared, Cefrine 300 mg Capsule helps reduce symptoms such as fever, pain, swelling, and congestion, allowing you to return to your daily activities more comfortably.
  • Helps Prevent Complications and Recurrence: Completing the full prescribed course of Cefrine 300 mg Capsule helps prevent the infection from spreading, reduces the risk of recurrence, and lowers the chance of antibiotic resistance developing.
Side effects of Cefrine 300 mg Capsule
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.
  • Your doctor may adjust the dose of your medication, discontinue, or switch to alternative medicines to manage your symptoms.
  • Drink plenty of water and caffeine-free drinks.
  • Eat more fibre by consuming fruits, vegetables, and whole grains.
  • Avoid processed, spicy, or fatty foods.
  • Try not to skip meals, delay eating, or eat too quickly.
  • Regular exercise can help improve digestion and promote better stool movement.

Directions for Use

  • Take Cefrine 300 mg Capsule with or without food as advised by your doctor.
  • It is advised to take Cefrine 300 mg Capsule 1 to 2 times daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Cefrine 300 mg Capsule as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Cefrine 300 mg Capsule Works

Cefrine 300 mg Capsule contains cefdinir, which belongs to a class of antibiotics known as cephalosporins. It works by interfering with the construction of the bacterial cell wall. Bacteria require a stable and intact cell wall to protect themselves from their environment and survive. By blocking the chemical processes needed to build this wall, Cefrine 300 mg Capsule causes the bacterial cells to rupture and die. Because human cells do not have cell walls, this medication selectively targets the infection without damaging your body's own cells.
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Alcohol

Caution

The interaction of Cefrine 300 mg Capsule with alcohol is unknown. Please consult a doctor before consuming alcohol while using Cefrine 300 mg Capsule .

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Pregnancy

Caution

Cefrine 300 mg Capsule is a category B pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

It is unknown whether Cefrine 300 mg Capsule is excreted in human milk. Cefrine 300 mg Capsule is given to breastfeeding mothers if the doctor thinks the benefits outweigh the risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Cefrine 300 mg Capsule may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking Cefrine 300 mg Capsule .

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Liver

Safe if prescribed

If you have any concerns regarding the use of Cefrine 300 mg Capsule in patients with liver problems, please consult a doctor.

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Kidney

Caution

Take Cefrine 300 mg Capsule with caution, especially if you have a history of Kidney diseases or conditions. Your doctor may adjust the dose as needed.

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Children

Caution

Cefrine 300 mg Capsule is not recommended for babies under 6 months of age as the safety and effectiveness have not been established.

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Heart

Consult your doctor

Please consult your doctor before using Cefrine 300 mg Capsule if you have pre-existing heart problems. Your doctor will prescribe Cefrine 300 mg Capsule if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Cefrine 300 mg Capsule to geriatric patients. Your doctor will prescribe Cefrine 300 mg Capsule if the benefits outweigh the risks.

What if I have taken an overdose of Cefrine 300 mg Capsule

If you suspect an overdose, or if someone has accidentally swallowed too much of this medication, seek immediate medical attention or call a nearby hospital right away.

Diet & Lifestyle Advise

  • Consider taking a probiotic supplement or eating yoghurt with active cultures a few hours after your dose to help maintain a healthy balance of gut bacteria.
  • Drink plenty of fluids, especially water, to help your body recover and stay hydrated during treatment.
  • Avoid eating iron-fortified cereals or taking multi-vitamins containing iron at the same time as this medication, as iron can significantly reduce its absorption.
  • Get plenty of rest to support your immune system as it fights off the infection.
     
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How Soon It Starts Working

The time required for Cefrine 300 mg Capsule to start to work: The effect of Cefrine 300 mg Capsule begins to take action within 2 to 4 hours of administration. The time for which the effects of Cefrine 300 mg Capsule last: The duration of Cefrine 300 mg Capsule ’s effect is clinically not established.

What if you forget to take Cefrine 300 mg Capsule

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store the capsules or tablets at controlled room temperature, between 20°C and 25°C (68°F to 77°F). •Keep the medication in its original container, tightly closed, to protect it from moisture and direct light.

Drug Warnings

  • Do not stop taking this medication early, even if you feel completely better. Stopping early can allow the remaining bacteria to multiply and become resistant to antibiotics.
  • Be aware that Cefrine 300 mg Capsule can interact with iron, which may cause your stool to turn a reddish-brown colour; this effect is harmless but should be discussed with your doctor if it concerns you.
  • Do not use over-the-counter anti-diarrhoea medicines if you develop severe diarrhoea while taking Cefrine 300 mg Capsule , as this can make the condition worse.
  • Let any healthcare provider know you are taking this medicine before having laboratory tests, as it can cause false results in certain urine glucose tests.

 

Drug-Drug Interactions

verifiedApollotooltip
  • Antacids (containing aluminium or magnesium): Taking these at the same time as Cefrine 300 mg Capsule reduces how much antibiotic your body absorbs. Separate these doses by at least two hours.
  • Iron supplements or multivitamins with iron: These can bind to the medicine in your digestive system, reducing its effectiveness. Take them at least two hours apart.
  • Probenecid: This medication can prevent your kidneys from clearing Cefrine 300 mg Capsule , leading to higher levels of the antibiotic in your blood and increasing the risk of side effects.
CefdinirBCG vaccine
Critical
CefdinirCholera, live attenuated
Severe

Drug-Drug Interactions

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CefdinirBCG vaccine
Critical
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with BCG vaccine may reduce the effects of BCG vaccine.

How to manage the interaction:
Taking Cefrine 300 mg Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
CefdinirCholera, live attenuated
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with Cholera vaccine can reduce the activity of the Cholera vaccine.

How to manage the interaction:
Taking Cefrine 300 mg Capsule with Cholera, live attenuated together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CefdinirHeparin
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with heparin may enhance the effects of heparin by anticoagulation(preventing blood from clotting).

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and Heparin can cause an interaction, it can be taken if a doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
CefdinirFondaparinux
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking fondaparinux and Cefrine 300 mg Capsule may increase the effects of fondaparinux.

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and Fondaparinux can evidently cause an interaction, it can be taken if your doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
CefdinirArgatroban
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with argatroban may lead to increase in the effects of Argatroban.

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and Argatroban together can evidently cause an interaction, but it can be taken if prescribed by a doctor. In case you experience any side effects like chest tightness, shortness of breath, swelling of legs, or palpitations, consult a doctor. Do not stop using any medications without first talking to your doctor.
CefdinirBivalirudin
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with bivalirudin may increase the effects of bivalirudin.

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and Argatroban together can evidently cause an interaction, but it can be taken if prescribed by a doctor. In case you experience any side effects like chest tightness, shortness of breath, swelling of legs, or palpitations, consult a doctor. Do not stop using any medications without first talking to your doctor.
CefdinirLepirudin
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with lepirudin may reduce the beneficial effects of therapy.

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.
CefdinirDalteparin
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with dalteparin together may decrease the therapeutic effects of dalteparin.

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and dalteparin can evidently cause an interaction, it can be taken if your doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Iron-fortified foods: Consuming foods highly fortified with iron close to your dose can lower the amount of medicine your body absorbs. Space them out by at least two hours.

 

CEFDINIR-300MGVitamin B complex foods, Vitamin B12 rich foods
Moderate

Drug-Food Interactions

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CEFDINIR-300MGVitamin B complex foods, Vitamin B12 rich foods
Moderate
Common Foods to Avoid:
Avocado, Beetroot, Cereals, Cheese, Chicken, Black Beans, Eggs, Clams, Chickpea, Whole Grains, Shellfish, Spinach, Salmon, Red Meat, Oysters, Potatoes, Kidney Beans, Mackerel, Milk, Kale, Tuna, Yogurt, Liver, Low-Fat Milk, Trout, Fortified Breakfast Cereal, Fish, Beef

How to manage the interaction:
Cefrine 300 mg Capsule and multivitamin with minerals should not be taken orally at the same time. Iron-containing products decreases the effects of Cefrine 300 mg Capsule. Although there is an interaction between Cefrine 300 mg Capsule and multivitamins, it can be taken if advised by a doctor. It should be taken two hours either before or after the dosage of the multivitamin with minerals.

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FAQs

Cefrine 300 mg Capsule is used to treat bacterial infections of the urinary tract, bones and joints, heart, lungs, brain, chest, ears, skin or soft tissues.
Cefrine 300 mg Capsule contains Cefdinir, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering), which is necessary for their survival. This damages the bacterial cell wall and kills bacteria.
It is not recommended to take Cefrine 300 mg Capsule with probenecid (used to lower high uric acid levels) as it may increase the levels of Cefrine 300 mg Capsule in the blood and increase the risk of adverse effects such as diarrhoea, kidney problems, vomiting, and nausea. However, please consult your doctor before taking Cefrine 300 mg Capsule with other medicines.
Cefrine 300 mg Capsule may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, avoid taking Cefrine 300 mg Capsule and consult a doctor immediately.
Cefrine 300 mg Capsule may interfere with the urine test (for sugar) and the Coombs test (for blood test), giving false-positive results. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Cefrine 300 mg Capsule .
Cefrine 300 mg Capsule is not used to treat viral infections; it is an antibiotic used only to treat bacterial infections.
Yes, but maintain at least a 2-hour gap between taking Cefrine 300 mg Capsule and antacids containing aluminium or magnesium because they can reduce the absorption and effectiveness of the antibiotic. Consult your doctor before taking any other medicines with Cefrine 300 mg Capsule .
Cefrine 300 mg Capsule can be used for a sore throat if it's caused by a bacterial infection like strep throat. It won't help if the sore throat is due to a virus, like a cold or the flu.
Do not stop taking Cefrine 300 mg Capsule just because you feel better. Complete the full course of treatment as directed by your doctor to ensure the infection is fully treated and prevent antibiotic resistance. Stopping early may make the infection harder to treat. Inform your doctor about your improved condition, and they will assess and advise whether to continue or discontinue the medication, prioritizing your safety.
Cefrine 300 mg Capsule is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
If you forget a dose of Cefrine 300 mg Capsule , take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.
If you don't feel better after taking Cefrine 300 mg Capsule , it's important to contact your doctor. Your symptoms might require a different dose or treatment, or there could be another underlying issue. Your doctor will examine your situation and provide the appropriate treatment. Don't stop the medication without consulting your healthcare provider first.
The common side effects of Cefrine 300 mg Capsule are diarrhoea, nausea, stomach pain, vomiting, rash, headache, vaginal itching or discharge. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
Store Cefrine 300 mg Capsule at room temperature, away from moisture and heat. Keep it out of the reach of children and pets.
While alcohol does not directly stop Cefrine 300 mg Capsule from working, it can dehydrate you, upset your stomach, and slow down your recovery. It is highly recommended to avoid alcohol while your body is healing. Talk to your doctor.
This can happen if you are taking Cefrine 300 mg Capsule at the same time as iron supplements or iron-rich products. The medicine binds to iron in your stomach, creating a harmless reddish-brown substance. Talk to your doctor.
If you have a mild reaction to penicillin, you may still be able to take Cefrine 300 mg Capsule safely. However, if you have a history of severe allergic reactions to penicillin, you should avoid it due to cross-sensitivity. Talk to your doctor.
This medicine should only be used during pregnancy if clearly needed. Small amounts of the medication can pass into breast milk, so consult your healthcare provider first. Talk to your doctor.
Yes, you can take Cefrine 300 mg Capsule with or without food. If you find that the medicine makes you feel slightly nauseous or causes an upset stomach, taking it with a meal can help. Talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - CEF1696
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