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compositionComposition:CAFFEINE CITRATE-20MG
prescription
Prescription Medicine
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Capnea Injection 1 ml is used to treat apnea in premature newborns/neonates. By activating the respiratory centre and making it more sensitive to hypercapnia, this medication helps control the mean respiratory rate and tidal volume and enhances pulmonary blood flow. Common side effects include a fast heartbeat, irregular heartbeat, and hyperglycemia. It is a pediatric medication. Inform your doctor if your newborn is allergic to Capnea Injection 1 ml.
 

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CAFFEINE CITRATE-20MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Capnea Injection 1 ml

Capnea Injection 1 ml is a prescription injection used to treat apnea of prematurity, which is a condition where premature babies have short periods of temporarily stopping breathing. It helps stimulate the baby's developing brain and lungs, encouraging regular and uninterrupted breathing. This medicine is mainly used in neonatal intensive care units (NICUs) under close medical supervision to support babies born too early.

This medicine is used to treat apnea of prematurity and may also help premature babies breathe on their own while they are being taken off mechanical ventilation. It works by stimulating the baby's breathing centre so breathing becomes more regular and consistent.

Because this medicine is given as an injection, it is administered by healthcare professionals, usually once a day at about the same time to maintain steady levels in the baby's body. Keeping the nursery environment calm and providing gentle physical contact may also support the baby's natural breathing pattern. The medical team will determine the timing of each dose to achieve the best possible results.

While this medicine is generally well tolerated, some babies may develop mild restlessness, spitting up, or a faster heart rate. These effects are usually temporary and are closely monitored by hospital staff. However, tell your doctor immediately if your baby develops severe stomach swelling, vomiting, or unusual shaking movements.

Do not use this medicine if your baby is allergic to any of its ingredients. Before treatment begins, tell your doctor if your baby has heart rhythm problems, kidney disease, liver disease, or seizures. Some medicines, particularly certain asthma medicines or seizure medicines, may affect how this medicine works or increase the risk of side effects. If you are breastfeeding, speak with your healthcare team about whether your medicines or diet could affect your baby.

Uses of Capnea Injection 1 ml

This medicine is used to support breathing in premature babies with underdeveloped lungs.

  • Apnea of prematurity: Helps treat short pauses in breathing in premature babies, ensuring they receive a steady supply of oxygen.
  • Support during ventilator removal: Helps premature babies breathe on their own while they are being transitioned away from mechanical breathing machines.

Key Benefits

This medicine provides important breathing support for premature babies during the early stages of life.

  • Supports regular breathing: Helps stabilise natural breathing patterns, reducing sudden drops in oxygen levels and easing the strain on a baby's lungs and heart.
  • Helps babies breathe independently sooner: May reduce the amount of time a premature baby needs mechanical ventilation, supporting a smoother transition to breathing room air.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Capnea Injection 1 ml should be administered by a nurse or a doctor.
  • Do not self-administer.

How Capnea Injection 1 ml Works

Capnea Injection 1 ml contains Caffeine Citrate. Caffeine citrate stimulates the breathing centre in the baby's brain, which controls automatic breathing. It makes this centre more responsive to the build-up of carbon dioxide, encouraging regular, deeper breaths and reducing pauses in breathing. It also strengthens the diaphragm, the main muscle used for breathing, widens the airways, and increases the number of breaths the baby takes each minute, helping the respiratory system work more effectively and consistently.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Caution

Capnea Injection 1 ml is intended for use in newborns/neonates only. If your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk.

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Driving

Not applicable

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Liver

Caution

Capnea Injection 1 ml should be used with caution in infants with impaired liver function.

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Kidney

Caution

Capnea Injection 1 ml should be used with caution in infants with impaired kidney function.

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Children

Consult your doctor

Capnea Injection 1 ml is intended for use in premature newborns and neonates. Consult your doctor for more information.

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Heart

Caution

Capnea Injection 1 ml should be used with caution in patients with heart problems. Therefore, please inform your doctor if your child has any heart problems.

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Geriatrics

Consult your doctor

Limited information is available on the use of Capnea Injection 1 ml in elderly patients. Please consult a doctor if you have any concerns about its use in elderly patients.

What if I have taken an overdose of Capnea Injection 1 ml

An overdose may cause a very fast heart rate, severe jitteriness, or seizures. Because this medicine is administered in a controlled hospital setting, the healthcare team will monitor your baby closely. If an overdose is suspected, they will immediately stop the injection and provide the necessary supportive care.

Diet & Lifestyle Advise

  • Maintain a calm nursery environment: Work closely with the neonatal care team to keep the nursery quiet and low stress, as this may help support stable breathing patterns in premature babies.
  • Follow the recommended feeding plan: Support regular, small feedings as recommended by your paediatrician, as this medicine may slightly increase your baby's metabolic rate and energy needs.
  • Practise skin-to-skin care: Gentle physical contact, such as Kangaroo care, may complement the medicine's effects on breathing stability when advised by your healthcare team.
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How Soon It Starts Working

The time required for Capnea Injection 1 ml to start to work: The onset time for Capnea Injection 1 ml is clinically unknown. The time for which the effects of Capnea Injection 1 ml last: The duration of action for Capnea Injection 1 ml is clinically unknown..

What if you forget to take Capnea Injection 1 ml

Since this medicine is given by healthcare professionals in a hospital, a missed dose is highly unlikely. If a scheduled injection is delayed for any reason, the healthcare team will safely adjust the treatment schedule. Do not request or attempt an extra dose.

Storage

• Store Capnea Injection 1 ml vials at room temperature, ideally between 15°C and 30°C.• Keep the vials in their original packaging to protect them from excessive heat and direct light.

Drug Warnings

  • Inspect the vial before use: The solution should be completely clear and colourless. Do not use it if you notice cloudiness, particles, or discolouration.
  • Monitor the injection site: Tell the nurse if you notice redness, swelling, irritation, or leaking fluid around the injection site.
  • Attend all recommended monitoring: The healthcare team may perform regular blood tests to measure the level of the medicine in your baby's blood and help keep treatment safe and effective.
  • Monitor heart rate during treatment: Temporary increases in heart rate are common, so your baby's heart rate will be monitored during and after the injection.

verifiedApollotooltip
  • Methylxanthines (i.e. theophylline): Using these medicines together may increase the risk of a rapid heartbeat and other side effects.
  • Stomach acid-reducing medicines (i.e. cimetidine): May increase the risk of stomach irritation in sensitive infants.
  • Antiseizure medicines (i.e. phenobarbital, phenytoin): May speed up how the baby's body processes caffeine citrate, which could reduce its effectiveness.

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verifiedApollotooltip

No clinically significant food interactions are known with Capnea Injection 1 ml when used as directed. 

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Capnea Injection 1 ml is used in the treatment of apnea of premature newborns.
Capnea Injection 1 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. This medicine stimulates the respiratory center, sensitizing it to hypercapnia. Thereby Capnea Injection 1 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, and enhances the breathing pattern.
No, it is intended to treat apnea in premature newborns and neonates.
The dosage is determined by your babys weight, medical problems, and responsiveness to therapy. Before determining the dose, it is also necessary to establish the baseline serum caffeine levels in children born to caffeine-consuming mothers.
It is used to treat apnea of prematurity, which is a condition where premature babies have short pauses in breathing because their breathing centre is not yet fully developed. Your baby's healthcare team can explain how this treatment supports your baby's recovery.
It is administered as a slow intravenous injection or infusion into a vein by a trained healthcare professional in a hospital setting. Speak with your baby's doctor if you have questions about the treatment process.
Yes. Mild restlessness, jitteriness, or temporary sleep disturbances are recognised side effects of this medicine. Tell your baby's doctor if these symptoms become severe or do not improve.
Yes. The healthcare team may perform blood tests to measure the level of the medicine in your baby's blood and make sure it remains within a safe and effective range.
Yes. Most babies can continue their usual feeding schedule while receiving this medicine. The healthcare team will monitor for stomach upset or spitting up and advise if any feeding changes are needed.
Because this medicine is given by healthcare professionals in a hospital, doses are carefully scheduled. If a delay occurs, the healthcare team will safely adjust the treatment schedule.
Available clinical evidence shows that short-term use of caffeine citrate to treat apnea of prematurity is generally safe and is not associated with long-term developmental problems. If you have concerns about your baby's long-term health, discuss them with the neonatal care team.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - CAP0093

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