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compositionComposition:ADAPALENE-1MG+CLINDAMYCIN-10MG+ZINC ACETATE-12MG
prescription
Prescription Medicine
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Capgel Plus Gel is used to treat acne (pimples). It contains adapalene, clindamycin, and zinc acetate. Adapalene works by loosening the cells on the skin's surface and unblocking pores by reducing the production of oil in the skin, thereby reducing the formation of pimples, whiteheads, and blackheads on the skin surface. Clindamycin stops or slows down the growth of bacteria, preventing the growth of acne. Zinc acetate, an antibacterial and anti-inflammatory agent, helps to reduce inflammation, prevent infection, and promote wound healing, further enhancing the treatment of acne and related skin conditions. In some cases, it may cause side effects such as skin peeling, dry skin, irritation, redness, itching, or a burning sensation at the site of application. Before using this medicine, inform your doctor if you are allergic to its components, pregnant, breastfeeding, taking any medications, or have pre-existing medical conditions.

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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy
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More about the Product

Composition :

ADAPALENE-1MG+CLINDAMYCIN-10MG+ZINC ACETATE-12MG

Manufacturer/Marketer :

Mesova Pharmaceuticals

Consume Type :

Topical

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Capgel Plus Gel

Capgel Plus Gel is a prescription topical gel primarily used to treat acne vulgaris. It targets multiple causes of acne, including clogged pores, acne-causing bacteria, and inflammation. This medicine helps clear existing pimples, blackheads, and whiteheads while helping prevent new breakouts from developing.

For the best results, use Capgel Plus Gel consistently once daily, usually in the evening, or exactly as directed by your doctor. Apply it to clean, completely dry skin after washing with a gentle, non-medicated cleanser. Following a simple skincare routine and staying well hydrated may also support your skin's natural healing process.

While using Capgel Plus Gel, you may notice mild skin irritation, redness, dryness, or a slight burning sensation, especially during the first few weeks of treatment. These effects are usually temporary as your skin adjusts to the medicine. However, stop using the gel and consult your doctor right away if you develop severe peeling, intense burning, severe swelling, or signs of an allergic reaction.

Do not use this medicine if you have inflammatory bowel disease (long-term inflammation of the digestive tract), ulcerative colitis (a condition that causes inflammation and ulcers in the large intestine), or severe colitis linked to previous antibiotic use. Tell your doctor if you have eczema or very sensitive skin before starting treatment, as this medicine may increase skin irritation.

Avoid using harsh soaps, exfoliating products, or other drying skin treatments unless your doctor recommends them. If you are pregnant, planning a pregnancy, or breastfeeding, speak with your doctor before using this medicine because adapalene is generally not recommended during pregnancy.

Uses of Capgel Plus Gel

Your doctor may prescribe Capgel Plus Gel to help manage the following conditions:

  • Acne vulgaris: Helps treat mild-to-moderate inflammatory acne (red, swollen pimples) and non-inflammatory acne (blackheads and whiteheads) by reducing blocked pores, bacteria, and inflammation.
  • Prevention of new breakouts: Helps keep pores clear and reduces acne-causing bacteria, lowering the chance of new pimples, blackheads, and whiteheads developing.
  • Reduction of skin inflammation: Helps relieve the redness, swelling, and discomfort associated with inflammatory acne.

Key Benefits

Capgel Plus Gel helps manage acne by treating several of its underlying causes with a single topical medicine.

  • Helps clear existing acne: Reduces pimples, blackheads, and whiteheads while improving the appearance of your skin.
  • Helps prevent future breakouts: Regular use helps keep pores clear and reduces acne-causing bacteria, lowering the risk of new acne lesions.
  • Reduces inflammation: Helps calm redness, swelling, and tenderness associated with inflamed acne.
  • Simplifies your skincare routine: Combines multiple acne-fighting ingredients into one daily treatment instead of requiring separate products.
Side effects of Capgel Plus Gel
  • After taking a shower or bath, apply a moisturizer to damp skin.
  • Use petroleum jelly or other thick emollients.
  • Use a hypoallergenic, fragrance-free moisturizer 2 to 3 times a day or as frequently as required.
  • Exfoliate your skin gently using a pumice stone or slightly abrasive sponge.
  • Do not scrub your skin.
  • Avoid hot showers or baths. Instead take short, warm showers or baths.
  • Use mild soap or skin cleansers with added moisturizer.
  • Drink lots of water.
  • Use sunscreen and wear protective clothing while going out to protect yourself from sun damage.
Here are the steps to manage medication-triggered Burning Or Stinging:
  • If you experience burning or stinging sensations and suspect that they may be related to medication, consult a doctor or healthcare expert to determine the cause and best course of treatment.
  • Avoid harsh products, extreme temperatures, and other potential irritants that may exacerbate burning or stinging.
  • Your healthcare professional may recommend applying a soothing or protective agent, such as a cream, gel, or ointment, to help alleviate burning or stinging.
  • Follow your healthcare professional's advice on how to care for the affected area, as gentle cleaning and care instructions may vary depending on the location and severity of the burning or stinging.
  • Schedule follow-up appointments with your doctor to monitor your symptoms and adjust your treatment plan as needed. If the burning or irritation persists or worsens, seek medical attention.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Avoid extreme heat or cold, like hot showers or cold winds, to prevent worsening skin discomfort.
  • Cool compresses: To reduce itch, redness, and swelling.
  • Avoid irritants like harsh chemicals or allergens to prevent worsening skin discomfort.
  • If you have severe itching, burning, or blistering seek medical attention.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Sunburns can occur commonly. Cover the area that is affected to avoid extended exposure.
  • Apply a clean, dampened towel to the affected skin for relief.
  • Take a cool bath by adding baking soda to water.
  • Sleep well and give enough rest to your body.
  • Take a balanced diet that heals the allergy or burns.
  • Apply a skin-calming lotion, gel or moisturiser frequently.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Apply a small amount of Capgel Plus Gel as a thin layer and gently rub it on the clean and dry affected area of the skin.
  • Wash your hands before and after applying Capgel Plus Gel. Before using it, wash the affected area with water.

How Capgel Plus Gel Works

Capgel Plus Gel contains three active ingredients that work together to treat acne. Adapalene is a retinoid-like medicine. It helps your skin shed dead skin cells more regularly, preventing them from clogging your pores. This helps treat existing acne and reduces the formation of new blackheads and whiteheads. Clindamycin is an antibiotic. It slows the growth of acne-causing bacteria and helps reduce the inflammation associated with acne. Zinc acetate helps enhance the antibacterial activity of clindamycin and may help reduce the development of antibiotic resistance. It also supports the skin's natural healing process.
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Alcohol

Caution

Interaction of Capgel Plus Gel with alcohol is unknown. Please consult a doctor before consuming alcohol while using Capgel Plus Gel.

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Pregnancy

Caution

The safety of Capgel Plus Gel in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Do not apply Capgel Plus Gel on the breast. You are advised to breastfeed only if the doctor thinks benefits are greater than risks.

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Driving

Safe if prescribed

Capgel Plus Gel usually does not affect your ability to drive or operate machinery.

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Liver

Safe if prescribed

If you have any concerns regarding the use of Capgel Plus Gel in case of liver problems, please consult a doctor.

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Kidney

Safe if prescribed

If you have any concerns regarding the use of Capgel Plus Gel in case of kidney problems, please consult a doctor.

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Children

Consult your doctor

Typically, Capgel Plus Gel is not recommended for children as the safety and effectiveness were not established. Please consult your doctor if you have concerns regarding it.

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Heart

Safe if prescribed

Capgel Plus Gel is generally considered safe for heart patients. However, please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Capgel Plus Gel is generally considered safe for geriatric patients. However, please consult your doctor if you have any concerns.

What if I have taken an overdose of Capgel Plus Gel

Applying more than the recommended amount of Capgel Plus Gel is unlikely to cause a serious problem, but it may lead to severe redness, peeling, dryness, or skin irritation. If a large amount of the gel is accidentally swallowed, seek immediate medical attention or go to the nearest emergency department.

Diet & Lifestyle Advise

  • Use non-comedogenic skincare products: Choose moisturisers, sunscreens, and cosmetics labelled 'non-comedogenic' because they are less likely to clog your pores.
  • Protect your skin from the sun: Apply a broad-spectrum sunscreen with SPF 30 or higher every day and wear protective clothing when outdoors because this medicine can make your skin more sensitive to sunlight.
  • Avoid picking or squeezing pimples: This reduces the risk of skin infection, delayed healing, and permanent acne scars.
  • Keep your hair clean and away from your face: Hair oils may contribute to blocked pores and acne breakouts.
  • Clean frequently touched items: Regularly wash pillowcases, makeup brushes, helmets, and mobile phone screens to reduce the build-up of oil and bacteria.
health query

Have a query?

How Soon It Starts Working

The time required for Capgel Plus Gel to start to work: Capgel Plus Gel may show visible effects on the skin after a few weeks of regular use. The time for which the effects of Capgel Plus Gel last: The duration of action for Capgel Plus Gel is clinically unknown.

What if you forget to take Capgel Plus Gel

If you miss an application, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your usual routine. Do not apply extra gel to make up for the missed application.

Storage

• Store Capgel Plus Gel at room temperature, preferably between 20°C and 25°C, or according to the storage instructions on the product label.

Drug Warnings

  • Do not apply to damaged skin: Avoid using the gel on cuts, open wounds, eczema, sunburnt skin, or severely irritated skin.
  • Avoid contact with the moist linings of the body: Keep the gel away from your eyes, nose, mouth, and other mucous membranes (the moist inner linings of these areas). If accidental contact occurs, rinse thoroughly with plenty of water.
  • Protect your skin from sunlight: Avoid prolonged sun exposure, tanning beds, and ultraviolet (UV) lamps during treatment because your skin becomes more sensitive to sunlight.
  • Avoid waxing (hair removal using wax): Do not use wax hair removal on treated areas because your skin may become more fragile and prone to irritation or peeling.
  • Be careful around hair and fabrics: Allow the gel to dry completely before it comes into contact with clothing or bedding.

Drug-Drug Interactions

verifiedApollotooltip
  • Other topical acne medicines (i.e. salicylic acid, sulphur, resorcinol): Using these medicines together may increase skin dryness, redness, peeling, and irritation.
  • Topical antibiotics (i.e. erythromycin): Using topical erythromycin together with clindamycin may reduce the effectiveness of clindamycin and is generally not recommended unless advised by your doctor.
  • Skin products containing alcohol or astringents (i.e. alcohol-based toners, witch hazel): These products may excessively dry or irritate your skin when used together with Capgel Plus Gel.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Capgel Plus Gel when used as directed.     
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIACNE]

FAQs

Capgel Plus Gel belongs to the class of dermatological preparations called 'antiacne' used to treat acne (pimples).
Capgel Plus Gel is a combination of three medicines, namely: Adapalene (human-made vitamin A), Clindamycin (antibiotic), and Zinc acetate. Adapalene works by loosening the cells on the skin’s surface and unblocking pores by reducing the production of oil in the skin, thereby reducing the formation of pimples, whiteheads, and blackheads on the skin surface. Clindamycin belongs to the class of antibiotics that works by inhibiting the production of essential proteins necessary for bacteria to grow, multiply, and increase in numbers, stopping or slowing down the growth of bacteria and preventing the growth of acne. Zinc acetate, an antibacterial and anti-inflammatory agent, helps reduce inflammation, prevent infection, and promote wound healing, while also regulating oil production and preventing comedone formation, reducing acne severity.
Yes, Capgel Plus Gel may cause photosensitivity (increased skin sensitivity to sunlight) in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use a sunscreen and wear protective clothing while going out to prevent sunburn.
No, Capgel Plus Gel is not recommended for eczema (itchy, cracked, swollen, or rough skin) patients as it may increase the risk of severe irritation. Therefore, if you are suffering from eczema, inform your doctor before using Capgel Plus Gel.
Yes, Capgel Plus Gel may cause skin irritation or sensitivity as a side effect. However, if the irritation persists or worsens, stop using Capgel Plus Gel and consult a doctor.
Yes, Capgel Plus Gel may cause dryness of the skin. You can use a moisturizer while using Capgel Plus Gel to prevent dry skin. However, do not apply Capgel Plus Gel and moisturizer at the same time, as it may reduce the effectiveness of Capgel Plus Gel. Please consult a doctor before using other products with Capgel Plus Gel.
You are advised to use Capgel Plus Gel for as long as it is advised by your doctor, even if your symptoms begin to improve after a short time. If you stop using Capgel Plus Gel too early, your acne may worsen or recur.
No, do not store Capgel Plus Gel in the freezer, as it may change its efficacy. Store it at room temperature only.
Capgel Plus Gel may take up to 2-3 weeks for your symptoms to improve. It may take some time to show effective results. Use Capgel Plus Gel as advised and inform your doctor if your symptoms do not improve or worsen.
You are advised to limit your time outside in the sun, as Capgel Plus Gel makes skin sensitive. If you must be in sunlight, you should wear sunscreen and wear a hat and clothes that cover the treated areas. You should avoid weather extremes such as cold and wind, as this may irritate your skin. Avoid using some skin products, such as astringents, harsh soaps, and cosmetics that have strong skin-drying effects. In addition, products with high alcohol levels should be avoided, as they may further irritate or dry your skin.
Apply a thin layer of Capgel Plus Gel to clean and dry affected areas. Wash your hands before and after applying it.
The common side effects of Capgel Plus Gel may include skin peeling, dry skin, irritation, redness, itching, or a burning sensation at the site of application. Most of these side effects of Capgel Plus Gel do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
It is generally recommended to apply Capgel Plus Gel once daily in the evening because the medicine can make your skin more sensitive to sunlight. If you need to go outdoors during the day, apply a broad-spectrum sunscreen and wear protective clothing.
Yes. You can use makeup, but apply Capgel Plus Gel first to clean, dry skin and allow it to dry completely before applying a non-comedogenic moisturiser or makeup. Choosing products labelled "non-comedogenic" may help reduce pore blockage.
Mild peeling and dryness are common when starting treatment. Applying a gentle, fragrance-free, non-comedogenic moisturiser may help. If the peeling becomes severe, painful, or is accompanied by intense redness, consult your doctor because your treatment may need to be adjusted.
Talk to your doctor before using this medicine if you are pregnant or planning to become pregnant. Because adapalene is generally avoided during pregnancy, your doctor will recommend the safest treatment option for you.
It is generally best to avoid medicated cleansers containing salicylic acid, sulphur, or other strong acne treatments unless your doctor recommends them. Using several acne medicines together may increase dryness, irritation, and peeling.
Unlike medicines containing benzoyl peroxide, Capgel Plus Gel does not usually bleach fabrics. However, allowing the gel to dry completely before it comes into contact with clothing, towels, or bedding helps prevent the medicine from rubbing off.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Adapalene Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Clindamycin Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Zinc Oxide Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Patrick B. Murphy; Karlyle G. Bistas; Jacqueline K. Le. Clindamycin. NIH National Library of Medicine, National center for biotechnology information. StatPearls. May 2022. [Accessed on 14th July 2022] /Check here
  5. Capitanio B., Sinagra J. L. Role of clindamycin and zinc acetate in topic acne therapy. Edizioni Minerva Medica. March 2012. [Accessed on 11th August 2022]Check here

Country of origin

India
Other Info - CAPG630
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