Adapalene+clindamycin+zinc Acetate
About Adapalene+clindamycin+zinc Acetate
Adapalene+clindamycin+zinc Acetate is a prescription topical gel primarily used to treat acne vulgaris. It targets multiple causes of acne, including clogged pores, acne-causing bacteria, and inflammation. This medicine helps clear existing pimples, blackheads, and whiteheads while helping prevent new breakouts from developing.
For the best results, use Adapalene+clindamycin+zinc Acetate consistently once daily, usually in the evening, or exactly as directed by your doctor. Apply it to clean, completely dry skin after washing with a gentle, non-medicated cleanser. Following a simple skincare routine and staying well hydrated may also support your skin's natural healing process.
While using Adapalene+clindamycin+zinc Acetate, you may notice mild skin irritation, redness, dryness, or a slight burning sensation, especially during the first few weeks of treatment. These effects are usually temporary as your skin adjusts to the medicine. However, stop using the gel and consult your doctor right away if you develop severe peeling, intense burning, severe swelling, or signs of an allergic reaction.
Do not use this medicine if you have inflammatory bowel disease (long-term inflammation of the digestive tract), ulcerative colitis (a condition that causes inflammation and ulcers in the large intestine), or severe colitis linked to previous antibiotic use. Tell your doctor if you have eczema or very sensitive skin before starting treatment, as this medicine may increase skin irritation.
Avoid using harsh soaps, exfoliating products, or other drying skin treatments unless your doctor recommends them. If you are pregnant, planning a pregnancy, or breastfeeding, speak with your doctor before using this medicine because adapalene is generally not recommended during pregnancy.
Uses of Adapalene+clindamycin+zinc Acetate
Medicinal Benefits
Adapalene+clindamycin+zinc Acetate helps manage acne by treating several of its underlying causes with a single topical medicine.
- Helps clear existing acne: Reduces pimples, blackheads, and whiteheads while improving the appearance of your skin.
- Helps prevent future breakouts: Regular use helps keep pores clear and reduces acne-causing bacteria, lowering the risk of new acne lesions.
- Reduces inflammation: Helps calm redness, swelling, and tenderness associated with inflamed acne.
- Simplifies your skincare routine: Combines multiple acne-fighting ingredients into one daily treatment instead of requiring separate products.
Directions for Use
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
- Apply a small amount of Adapalene+clindamycin+zinc Acetate as a thin layer and gently rub it on the clean and dry affected area of the skin.
- Wash your hands before and after applying Adapalene+clindamycin+zinc Acetate. Before using it, wash the affected area with water.
Storage
Side Effects of Adapalene+clindamycin+zinc Acetate
Common Side Effects (Usually mild)
- Dry or peeling skin
- Mild redness or skin irritation
- Mild burning, itching, or stinging where the gel is applied
- Increased sensitivity to sunlight, making your skin more likely to sunburn
Serious Side Effects (Consult your doctor right away)
- Severe or persistent burning, redness, swelling, or peeling of the skin
- Signs of a severe allergic reaction, such as hives, swelling of the face, lips, tongue, or throat, or difficulty breathing
- Severe, persistent, watery, or bloody diarrhoea, which may indicate a serious bowel problem associated with clindamycin
Medicines Containing this Salt
View AllDrug Warnings
- Do not apply to damaged skin: Avoid using the gel on cuts, open wounds, eczema, sunburnt skin, or severely irritated skin.
- Avoid contact with the moist linings of the body: Keep the gel away from your eyes, nose, mouth, and other mucous membranes (the moist inner linings of these areas). If accidental contact occurs, rinse thoroughly with plenty of water.
- Protect your skin from sunlight: Avoid prolonged sun exposure, tanning beds, and ultraviolet (UV) lamps during treatment because your skin becomes more sensitive to sunlight.
- Avoid waxing (hair removal using wax): Do not use wax hair removal on treated areas because your skin may become more fragile and prone to irritation or peeling.
- Be careful around hair and fabrics: Allow the gel to dry completely before it comes into contact with clothing or bedding.
Drug Interactions
- Other topical acne medicines (i.e. salicylic acid, sulphur, resorcinol): Using these medicines together may increase skin dryness, redness, peeling, and irritation.
- Topical antibiotics (i.e. erythromycin): Using topical erythromycin together with clindamycin may reduce the effectiveness of clindamycin and is generally not recommended unless advised by your doctor.
- Skin products containing alcohol or astringents (i.e. alcohol-based toners, witch hazel): These products may excessively dry or irritate your skin when used together with Adapalene+clindamycin+zinc Acetate.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionInteraction of Adapalene+clindamycin+zinc Acetate with alcohol is unknown. Please consult a doctor before consuming alcohol while using Adapalene+clindamycin+zinc Acetate.
Pregnancy
cautionThe safety of Adapalene+clindamycin+zinc Acetate in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
cautionDo not apply Adapalene+clindamycin+zinc Acetate on the breast. You are advised to breastfeed only if the doctor thinks benefits are greater than risks.
Driving
safe if prescribedAdapalene+clindamycin+zinc Acetate usually does not affect your ability to drive or operate machinery.
Liver
safe if prescribedIf you have any concerns regarding the use of Adapalene+clindamycin+zinc Acetate in case of liver problems, please consult a doctor.
Kidney
safe if prescribedIf you have any concerns regarding the use of Adapalene+clindamycin+zinc Acetate in case of kidney problems, please consult a doctor.
Children
consult your doctorTypically, Adapalene+clindamycin+zinc Acetate is not recommended for children as the safety and effectiveness were not established. Please consult your doctor if you have concerns regarding it.
Habit Forming
Diet & Lifestyle Advise
- Use non-comedogenic skincare products: Choose moisturisers, sunscreens, and cosmetics labelled 'non-comedogenic' because they are less likely to clog your pores.
- Protect your skin from the sun: Apply a broad-spectrum sunscreen with SPF 30 or higher every day and wear protective clothing when outdoors because this medicine can make your skin more sensitive to sunlight.
- Avoid picking or squeezing pimples: This reduces the risk of skin infection, delayed healing, and permanent acne scars.
- Keep your hair clean and away from your face: Hair oils may contribute to blocked pores and acne breakouts.
- Clean frequently touched items: Regularly wash pillowcases, makeup brushes, helmets, and mobile phone screens to reduce the build-up of oil and bacteria.
Special Advise
- You are advised to apply any other lotions, creams, or ointments, including cosmetics and moisturizers, after 30 minutes of applying Adapalene+clindamycin+zinc Acetate, as using both at the same time may reduce the effectiveness of Adapalene+clindamycin+zinc Acetate.
- Do not squeeze, pop, or pick spots, as it may worsen them and cause permanent scarring.
- Avoid contact of Adapalene+clindamycin+zinc Acetate with nose, mouth, eyes, or ears. In case Adapalene+clindamycin+zinc Acetate comes in contact with these areas accidentally, rinse with water.
Patients Concern
Disease/Condition Glossary
Acne (pimples): It is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads. Acne affects people of all ages, but it is most common among teenagers. The symptoms of acne include pus-filled pimples, uninflamed (not swollen) blackheads, and red, large, and tender bumps. The treatment for acne includes certain creams, cleansers, and antibiotics.
FAQs
Adapalene+clindamycin+zinc Acetate belongs to the class of dermatological preparations called 'antiacne' used to treat acne (pimples).
Adapalene+clindamycin+zinc Acetate is a combination of three medicines, namely: Adapalene (human-made vitamin A), Clindamycin (antibiotic), and Zinc acetate. Adapalene works by loosening the cells on the skin’s surface and unblocking pores by reducing the production of oil in the skin, thereby reducing the formation of pimples, whiteheads, and blackheads on the skin surface. Clindamycin belongs to the class of antibiotics that works by inhibiting the production of essential proteins necessary for bacteria to grow, multiply, and increase in numbers, stopping or slowing down the growth of bacteria and preventing the growth of acne. Zinc acetate, an antibacterial and anti-inflammatory agent, helps reduce inflammation, prevent infection, and promote wound healing, while also regulating oil production and preventing comedone formation, reducing acne severity.
Yes, Adapalene+clindamycin+zinc Acetate may cause photosensitivity (increased skin sensitivity to sunlight) in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use a sunscreen and wear protective clothing while going out to prevent sunburn.
No, Adapalene+clindamycin+zinc Acetate is not recommended for eczema (itchy, cracked, swollen, or rough skin) patients as it may increase the risk of severe irritation. Therefore, if you are suffering from eczema, inform your doctor before using Adapalene+clindamycin+zinc Acetate.
Yes, Adapalene+clindamycin+zinc Acetate may cause skin irritation or sensitivity as a side effect. However, if the irritation persists or worsens, stop using Adapalene+clindamycin+zinc Acetate and consult a doctor.
Yes, Adapalene+clindamycin+zinc Acetate may cause dryness of the skin. You can use a moisturizer while using Adapalene+clindamycin+zinc Acetate to prevent dry skin. However, do not apply Adapalene+clindamycin+zinc Acetate and moisturizer at the same time, as it may reduce the effectiveness of Adapalene+clindamycin+zinc Acetate. Please consult a doctor before using other products with Adapalene+clindamycin+zinc Acetate.
You are advised to use Adapalene+clindamycin+zinc Acetate for as long as it is advised by your doctor, even if your symptoms begin to improve after a short time. If you stop using Adapalene+clindamycin+zinc Acetate too early, your acne may worsen or recur.
No, do not store Adapalene+clindamycin+zinc Acetate in the freezer, as it may change its efficacy. Store it at room temperature only.
Adapalene+clindamycin+zinc Acetate may take up to 2-3 weeks for your symptoms to improve. It may take some time to show effective results. Use Adapalene+clindamycin+zinc Acetate as advised and inform your doctor if your symptoms do not improve or worsen.
You are advised to limit your time outside in the sun, as Adapalene+clindamycin+zinc Acetate makes skin sensitive. If you must be in sunlight, you should wear sunscreen and wear a hat and clothes that cover the treated areas. You should avoid weather extremes such as cold and wind, as this may irritate your skin. Avoid using some skin products, such as astringents, harsh soaps, and cosmetics that have strong skin-drying effects. In addition, products with high alcohol levels should be avoided, as they may further irritate or dry your skin.
Apply a thin layer of Adapalene+clindamycin+zinc Acetate to clean and dry affected areas. Wash your hands before and after applying it.
The common side effects of Adapalene+clindamycin+zinc Acetate may include skin peeling, dry skin, irritation, redness, itching, or a burning sensation at the site of application. Most of these side effects of Adapalene+clindamycin+zinc Acetate do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
It is generally recommended to apply Adapalene+clindamycin+zinc Acetate once daily in the evening because the medicine can make your skin more sensitive to sunlight. If you need to go outdoors during the day, apply a broad-spectrum sunscreen and wear protective clothing.
Yes. You can use makeup, but apply Adapalene+clindamycin+zinc Acetate first to clean, dry skin and allow it to dry completely before applying a non-comedogenic moisturiser or makeup. Choosing products labelled 'non-comedogenic' may help reduce pore blockage.
Mild peeling and dryness are common when starting treatment. Applying a gentle, fragrance-free, non-comedogenic moisturiser may help. If the peeling becomes severe, painful, or is accompanied by intense redness, consult your doctor because your treatment may need to be adjusted.
Talk to your doctor before using this medicine if you are pregnant or planning to become pregnant. Because adapalene is generally avoided during pregnancy, your doctor will recommend the safest treatment option for you.
It is generally best to avoid medicated cleansers containing salicylic acid, sulphur, or other strong acne treatments unless your doctor recommends them. Using several acne medicines together may increase dryness, irritation, and peeling.
Unlike medicines containing benzoyl peroxide, Adapalene+clindamycin+zinc Acetate does not usually bleach fabrics. However, allowing the gel to dry completely before it comes into contact with clothing, towels, or bedding helps prevent the medicine from rubbing off.
