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compositionComposition:BIAPENEM-300MG
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Prescription Medicine
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Biup Injection is indicated to treat a wide range of various bacterial infectious diseases such as Septicemia, Lower respiratory infections, Complicated urinary tract infections and Intra-abdominal infections. It contains Biapenem; it penetrates the cell wall of most gram-positive/gram-negative bacteria to bind penicillin-binding protein (PBP) targets and inhibits bacterial cell wall synthesis, thereby killing the bacteria and treating bacterial infection. In some cases, this medication may cause side effects such as injection site reactions, diarrhoea, nausea, and vomiting.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BIAPENEM-300MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Biup Injection

Biup Injection is an injectable antibiotic used to treat severe, complicated bacterial infections inside the body. It is typically prescribed for serious conditions like severe lung infections, deep stomach infections, and complicated urinary tract infections. This medicine helps clear the body of harmful bacteria, allowing your system to heal.
Because this medicine must be injected directly into a vein, it is usually given by a healthcare professional at regular, scheduled times. This consistent schedule ensures a steady amount of the medicine remains in your blood to fight the infection. Since it is injected, you do not need to worry about taking it with or without food, but drinking plenty of water and resting will help your body recover faster.
While using Biup Injection, some people may experience mild side effects like nausea or slight redness at the injection site. However, you should consult your doctor immediately if you experience serious side effects, such as severe watery diarrhoea, seizures, or signs of liver damage like yellowing of the skin or eyes.
Do not take this if you have had a severe allergic reaction to similar antibiotics in the past. Before starting this treatment, talk to your doctor if you have a history of kidney disease, seizures, or asthma, as these conditions may require extra caution or a different approach.
This medicine can interact with certain other drugs, especially some medications used to treat epilepsy, making them less effective and increasing seizure risks. If you are pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist to ensure this treatment is safe for you.

Uses of Biup Injection

Biup Injection may be prescribed to treat the following types of bacterial infections:

  • Lower respiratory tract infections: Helps clear deep chest and lung infections, such as severe pneumonia.
  • Intra-abdominal infections: Treats serious bacterial infections inside the belly, including peritonitis.
  • Complicated urinary tract infections: Targets severe infections in the kidneys or bladder that do not respond to standard treatments.
  • Gynaecological infections: Resolves severe bacterial infections in the pelvic and reproductive organs.

Key Benefits

Biup Injection is a carbapenem antibiotic used to treat serious bacterial infections. It works by interfering with bacterial cell-wall formation, helping eliminate susceptible bacteria and control the infection.

  • Treats Serious Bacterial Infections: Helps eliminate susceptible bacteria responsible for complicated infections that may require injectable antibiotic treatment.
  • Provides Broad-Spectrum Antibacterial Action: Acts against a wide range of susceptible bacteria, making it useful for certain complicated infections.
  • Helps Control Infection-Related Symptoms: As the bacterial infection improves, symptoms such as fever, pain, swelling, and general weakness may gradually decrease.
  • Helps Prevent the Spread of Infection: Effective treatment can reduce the risk of a serious infection worsening or spreading to other parts of the body.
  • Supports Recovery: By controlling the underlying bacterial infection, it helps support recovery and a return to normal activities.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Biup Injection will be administered by a nurse or doctor.
  • Do not self-administer.

How Biup Injection Works

Biup Injection contains biapenem. It belongs to a class of medicines known as carbapenem antibiotics. It works by interfering with the bacteria's ability to build their protective cell walls. Without a strong outer wall, the bacterial cells cannot survive the pressure within the body, causing them to burst and die. This targeted action specifically destroys the bacteria causing the illness while sparing your body's cells, which do not have cell walls. By rapidly reducing the number of active bacteria, it allows your natural immune system to take over and completely clear the infection.
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Alcohol

Caution

It is not known if alcohol affects Biup Injection. However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Caution

Please consult the doctor, as there are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited information is available. Please consult the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the medicine to the mother.

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Driving

Caution

It is unknown whether Biup Injection alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

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Liver

Caution

Limited information regarding using Biup Injection in patients suffering from liver impairment is available. Please inform your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Monitor and administer Biup Injection carefully. Reducing the dose or increasing the dosing interval is necessary in patients with severe kidney impairment.

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Children

Safe if prescribed

There was limited information about the usage of Biup Injection in paediatric patients. Please seek medical advice. Only if the benefits exceed the dangers will your doctor prescribe.

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Heart

Consult your doctor

Please consult your doctor before receiving Biup Injection if you have pre-existing heart problems. Your doctor will prescribe Biup Injection if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Biup Injection to geriatric patients. Your doctor will prescribe Biup Injection if the benefits outweigh the risks.

What if I have taken an overdose of Biup Injection

If you suspect an overdose, seek immediate medical attention. Symptoms of an overdose may include confusion, muscle twitching, or seizures. Contact your local emergency services or visit the nearest hospital emergency room right away.

Diet & Lifestyle Advise

  • Stay Well-Hydrated: Drink adequate fluids unless your doctor has advised you to restrict them, particularly if you have kidney or heart problems.
  • Support Gut Health: If appropriate for you, probiotic-rich foods such as plain yoghurt may help support healthy gut bacteria during or after antibiotic treatment.
  • Get Adequate Rest: Allow your body sufficient rest and sleep while recovering from the infection.
  • Avoid Excessive Alcohol: Limit or avoid alcohol while recovering from a serious infection, particularly if you feel unwell or are taking other medicines that may affect the liver.
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How Soon It Starts Working

The time required for Biup Injection to start to work: The time required for Biup Injection to show its action is not clinically established. The time for which the effects of Biup Injection last: The duration of action for Biup Injection is not clinically established.

What if you forget to take Biup Injection

Since this medicine is usually given by a healthcare professional, a missed dose is unlikely. However, if you are managing your treatment at home and miss a scheduled dose, contact your doctor or nurse immediately for guidance. Do not inject a double dose to make up for a missed one.

Storage

•Store unmixed vials of Biup Injection at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the medication in its original package to protect it from direct light and moisture, and do not freeze it.

Drug Warnings

  • Inspect the Injection Before Use: Do not use the solution if it appears discoloured, cloudy, or contains visible particles.
  • Complete the Prescribed Course: Take Biup Injection for the full duration recommended by your doctor, even if your symptoms improve earlier.
  • Monitor the Injection Site: Inform your healthcare provider if you develop increasing pain, redness, warmth, swelling, or other signs of irritation at the injection site.
  • Inform Your Doctor About Seizure Disorders: Tell your doctor if you have a history of epilepsy, seizures, or other neurological disorders, as carbapenem antibiotics may increase the risk of seizures in susceptible individuals.
  • Report Severe Diarrhoea: Contact your doctor if you develop severe, persistent, watery, or bloody diarrhoea during or after treatment. Do not take anti-diarrhoeal medicines without medical advice, as they may be inappropriate in antibiotic-associated diarrhoea.

Drug-Drug Interactions

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Inform your doctor about all medicines you are taking before receiving Biup Injection, particularly the following:

  • Valproic acid: Combining this antibiotic with valproic acid can significantly lower the levels of the seizure medication in your blood, increasing your risk of experiencing a seizure.
  • Probenecid: Taking this medication alongside probenecid can slow down how quickly your kidneys clear the antibiotic, which may increase its concentration in your body and prolong its effects.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No clinically significant food interactions are known with Biup Injection when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Biup Injection is used to treat bacterial infections.
Biup Injection contains biapenem, a carbapenem antibiotic that has broad-spectrum antibacterial action against Gram-positive and Gram-negative aerobic and anaerobic bacteria by blocking the formation of bacterial cell walls.
After taking an antibiotic, you may need to wait up to three hours before eating or drinking any dairy products, including milk, butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also affect the working of antibiotics.
This medicine is injected directly into a vein as an infusion, typically by a doctor or nurse in a clinical setting. If you are instructed to use it at home, follow your healthcare provider's training precisely. Talk to your doctor if you have questions about the injection process.
It is highly recommended to avoid alcohol while treating a severe infection. Alcohol can dehydrate your body, weaken your immune system, and strain your liver while it is processing your medication. Talk to your doctor or pharmacist for personalised advice.
Mild diarrhoea can happen, but if you develop severe, watery diarrhoea or stomach cramps, contact your doctor immediately. Do not take any over-the-counter anti-diarrhoea medicines without speaking to your healthcare provider first, as this could make the condition worse. Talk to your doctor if you experience changes in bowel habits.
This medicine should only be used during pregnancy if the potential benefits clearly outweigh the risks to the unborn baby. If you are pregnant or planning to become pregnant, talk to your doctor before starting this medication.
While uncommon, this class of antibiotics can trigger seizures, particularly in people who already have a history of epilepsy, kidney problems, or central nervous system disorders. Talk to your doctor if you have any history of seizures before starting treatment.
If you have had a severe allergic reaction to penicillin, you may also be allergic to this medicine. Be sure to discuss all your past drug allergies with your healthcare provider. Talk to your doctor or pharmacist to find the safest treatment option for you.
No, you should never stop your treatment early, even if you feel completely recovered. Stopping too soon can allow the remaining bacteria to multiply, causing the infection to return and potentially become resistant to antibiotics. Talk to your doctor before making any changes to your treatment.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - BIU0002
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