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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Arpimune ME 50 Tablet is used to prevent organ transplant rejection. It is also used to treat inflammation and pain associated with psoriasis and rheumatoid arthritis. This medicine contains cyclosporine, which works by suppressing the immune system. It also helps reduce rapid skin cell growth, pain, and inflammation. It may sometimes cause common side effects such as headaches, vomiting, nausea, loss of appetite, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Synonym :

CYCLOSPORIN

Composition :

CYCLOSPORINE-50MG

Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Arpimune ME 50 Tablet

Arpimune ME 50 Tablet belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ rejection after a transplant. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.

Arpimune ME 50 Tablet contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and lowers pain and inflammation in the joints.

Arpimune ME 50 Tablet may cause side effects like headaches, vomiting, nausea, loss of appetite and diarrhoea. Most of these side effects do not require medical attention and resolve over time. However, consult your doctor if the side effects persist or worsen.

To treat your condition effectually, continue taking Arpimune ME 50 Tablet for as long as your doctor has prescribed. Inform your doctor about your health condition and any medications you are taking to help rule out any potential/unpleasant side effects.

Uses of Arpimune ME 50 Tablet

Arpimune ME 50 Tablet is used to prevent organ rejection and treat psoriasis and rheumatoid arthritis. The detailed uses of Arpimune ME 50 Tablet are as follows:

  • Treatment of Organ Transplant Rejection: Arpimune ME 50 Tablet is used in the prevention of organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants.
  • Treatment of Psoriasis: Arpimune ME 50 Tablet is used in the treatment of psoriasis. It helps reduce rapid skin cell growth and inflammation caused by psoriasis.
  • Treatment of Rheumatoid Arthritis: Arpimune ME 50 Tablet is used in the treatment of rheumatoid arthritis. It helps reduce pain and inflammation in the joints and slows down joint damage.

Directions for Use

  • Arpimune ME 50 Tablet can be taken with or without food.
  • It is usually taken 2 times a day or as prescribed by your doctor.
  • Swallow Arpimune ME 50 Tablet as a whole with a glass of water.
  • Do not crush, chew, or open it.

Medicinal Benefits

  • Arpimune ME 50 Tablet suppresses the immune system to prevent the rejection of transplanted organs (e.g., kidney, liver, heart).
  • It is also used in bone marrow and stem cell transplantation to prevent graft rejection.
  • Arpimune ME 50 Tablet helps control immune overactivity in various autoimmune conditions by blocking immune cells that attack the body’s own tissues.
  • It reduces rapid skin cell growth and inflammation in severe psoriasis, leading to clearer skin and symptom relief.
  • This medicine reduces joint pain, inflammation, and slows down joint damage in patients with active rheumatoid arthritis unresponsive to other therapies.
  • It may also be used to treat severe atopic dermatitis, especially in patients who do not respond adequately to topical treatments.
  • Helps manage severe inflammatory eye diseases that can threaten vision by reducing immune-mediated damage.
  • It is used in certain cases of nephrotic syndrome (a kidney disorder causing excess protein loss in urine), especially when other treatments fail.

How Arpimune ME 50 Tablet Works

Arpimune ME 50 Tablet contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and the production of interleukins (molecules involved in inflammation). Additionally, it also reduces pain and inflammation in the joints and slows down the joint damage caused by an overactive immune system.

Storage

• Store in a cool and dry place away from sunlight.• Keep Arpimune ME 50 Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Arpimune ME 50 Tablet

Take Arpimune ME 50 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Symptoms of overdose may include headache, drowsiness, vomiting, increased heart rate, and liver and kidney toxicity. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Arpimune ME 50 Tablet if you are allergic to any of the components.
  • Let your doctor know before using Arpimune ME 50 Tablet if you have/had liver or kidney problems, epilepsy, high blood pressure, low levels of magnesium, high levels of potassium, cancer, or infection.
  • Arpimune ME 50 Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.
  • Before taking Arpimune ME 50 Tablet, inform your doctor if you have any type of cancer.
  • Consult your doctor before taking Arpimune ME 50 Tablet if you are pregnant or planning for pregnancy.
  • Arpimune ME 50 Tablet should not be taken by breastfeeding mothers as it passes into breast milk.
  • Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities, such as 20-30 minutes of walking or swimming, would be helpful.
  • Practising yoga may also help improve joint flexibility and manage pain.
  • Maintain a healthy weight by engaging in regular low-impact exercises and eating a balanced diet.
  • Get adequate sleep, as rest can help reduce inflammation and swelling.
  • Follow heat or cold therapy by applying a cold or hot compress to the joints for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  • Foods containing flavonoids can help reduce inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Arpimune ME 50 Tablet. It could lead to increased dizziness and drowsiness.

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Pregnancy

Caution

It is not known whether Arpimune ME 50 Tablet will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant.

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Breast Feeding

Unsafe

It is not recommended to take Arpimune ME 50 Tablet while you are breastfeeding. Arpimune ME 50 Tablet passes into breast milk.

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Driving

Caution

Drive or operate machinery only if you are alert.

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Liver

Caution

Take Arpimune ME 50 Tablet only if prescribed by the doctor, especially if you are dealing with Liver diseases/conditions, as your doctor may adjust the dose as required.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment before taking Arpimune ME 50 Tablet.

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Children

Unsafe

Arpimune ME 50 Tablet should not be given to children, as the efficacy and safety have not been established.

Have a query?

FAQs

Arpimune ME 50 Tablet belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.

Arpimune ME 50 Tablet acts as an immunosuppressant, which helps reduce pain and inflammation in the joints and prevent joint stiffness, thereby relieving rheumatoid arthritis.

If you miss a dose of Arpimune ME 50 Tablet, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose. Do not take a double dose to make up for a missed one.

Diarrhoea might be a side-effect of Arpimune ME 50 Tablet. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, using Arpimune ME 50 Tablet may cause abnormal hair growth, although it does not affect everybody. Consult your doctor if you have any concerns.

Arpimune ME 50 Tablet is known to decrease the immune system. As a result, it increases your risk of developing certain types of cancer, especially skin cancer. You should reduce your contact with sunlight and UV light by wearing suitable protective clothing. Sunscreen should be used regularly.

No, Arpimune ME 50 Tablet is not a steroid. It is an immunosuppressant.

Yes, cyclosporine can cause weight gain. However, this is not a common side effect, and the amount of weight gain varies from person to person.

Yes, fatigue is a common side effect of cyclosporine. Many people who take cyclosporine report feeling tired or fatigued.

Arpimune ME 50 Tablet is an immunosuppressant medication, meaning it weakens your immune system. This can make you more susceptible to infections and other health problems. Your doctor will likely order regular blood tests to monitor your health and ensure the medication is working effectively.

Arpimune ME 50 Tablet has not been definitively linked to causing cancer. However, discussing any concerns you may have with your doctor is essential. They can provide personalized information about your health situation and why you take cyclosporine.

Common side effects of Arpimune ME 50 Tablet may include headaches, vomiting, nausea, high blood pressure, increased hair growth, loss of appetite (feeling unwell and upset stomach), kidney disease, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Arpimune ME 50 Tablet ideally should be given 12 hours apart. The capsules should be taken with water and swallowed whole. Grapefruit and grapefruit juice should be avoided, as they can increase ciclosporin levels in the blood.

The duration of Arpimune ME 50 Tablet treatment varies depending on the underlying condition and individual response.

Always consult with your doctor or pharmacist before starting any new medications or supplements while taking Arpimune ME 50 Tablet. They can help you identify potential interactions and recommend safe alternatives if necessary.

Yes, you can travel while taking cyclosporine. However, it's essential to plan and take necessary precautions. Ensure you have a sufficient supply of your medication, and be aware of any potential customs regulations or travel restrictions.

Generally, moderate exercise is safe while taking Arpimune ME 50 Tablet. However, listening to your body and avoiding overexertion is essential, especially if you have any underlying health conditions.

Excessive alcohol consumption can increase the risk of side effects and interact with cyclosporine. It's best to limit alcohol intake or avoid it altogether while taking this medication.

Your doctor will determine the frequency of your blood tests based on your situation. However, regular monitoring is essential to ensure that cyclosporine works effectively and detects potential side effects.

If you miss a dose of Arpimune ME 50 Tablet, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Some people may experience mood changes or anxiety while taking Arpimune ME 50 Tablet. If you notice any changes in your mental health, it's important to talk to your doctor.

Arpimune ME 50 Tablet occasionally causes blurred vision or eye irritation. If you experience any vision problems, contact your doctor.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.

Taking more than the recommended dosage does not provide additional benefit and can increase the risk of adverse effects.

Arpimune ME 50 Tablet contains cyclosporine, an immunosuppressant.

Arpimune ME 50 Tablet should not be given to children, as the efficacy and safety have not been established.

Country of origin

India

Manufacturer/Marketer address

463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA
Other Info - ARP0018

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