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compositionComposition:HYDRALAZINE-20MG
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Prescription Medicine
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Apresol Injection 1 ml is an anti-hypertensive medication used to treat very high blood pressure, particularly in pregnancy and in patients with kidney disease. It contains Hydralazine, a vasodilator that works by relaxing and widening the walls of blood vessels. Thus, it increases blood and oxygen supply to the heart and reduces blood pressure. Common side effects of Apresol Injection 1 ml are headaches, abnormal heartbeat, nausea, diarrhoea, chest pain, and muscle or joint pain.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

HYDRALAZINE-20MG

Manufacturer/Marketer :

Ordain Health Care Global Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Apresol Injection 1 ml

Apresol Injection 1 ml is an injectable medicine used to quickly lower dangerously high blood pressure in emergency situations. It helps protect critical organs by reducing the pressure on your heart and blood vessels when blood pressure spikes to unsafe levels. This fast-acting treatment is typically used in clinical settings when oral medications cannot be taken or are not working quickly enough.

Because this medication is usually injected in urgent situations, it is used on a short-term basis as directed by your healthcare team rather than as a daily routine. For long-term blood pressure control, your doctor will likely recommend a combination of regular oral medications and key lifestyle habits. Adopting a low-salt diet, staying physically active, and managing stress are essential steps to keep your heart healthy over time.

While receiving this medicine, you might experience mild side effects like a headache, a fast heartbeat, or mild nausea. These symptoms are common as your body adjusts to the rapid lowering of your blood pressure, but you must tell your medical team immediately if they become severe or if you experience chest pain. Your doctor will closely monitor your vital signs to ensure your safety throughout the process.

Before you receive Apresol Injection 1 ml, tell your doctor if you have a history of heart disease, stroke, or kidney problems. Do not take this if you have coronary artery disease or rheumatic heart disease, as this medicine can worsen these conditions. It is also important to tell your medical team if you have ever had lupus or similar autoimmune conditions.

This medicine can interact with other blood pressure drugs, alcohol, and certain pain relievers, which can cause your blood pressure to drop too low. If you are pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to discuss the risks and benefits of this treatment in your specific situation.

Uses of Apresol Injection 1 ml

Apresol Injection 1 ml helps rapidly lower dangerously high blood pressure in emergency situations. Your doctor may prescribe it for the following conditions:

  • Severe high blood pressure (hypertensive crisis): Apresol Injection 1 ml quickly relaxes the walls of your blood vessels, allowing blood to flow more easily and rapidly lowering dangerously high blood pressure.
  • High blood pressure during pregnancy (preeclampsia or eclampsia): This medicine is used to safely and quickly control severe blood pressure spikes in pregnant women, protecting both the mother and the baby from complications.

Key Benefits

Using Apresol Injection 1 ml as prescribed helps rapidly lower dangerously high blood pressure during medical emergencies. Here are the key benefits you can expect:

  • Rapid blood pressure control: Apresol Injection 1 ml quickly lowers blood pressure to a safer range, helping reduce the immediate risk of serious complications such as stroke, heart attack, or kidney failure.
  • Reduces strain on the heart: By widening the blood vessels, it helps your heart pump blood more efficiently with less effort.
  • Provides fast symptom relief: It can quickly relieve symptoms associated with severe high blood pressure, such as severe headache, chest tightness, and blurred vision, helping you feel more comfortable.
  • Supports emergency stabilisation: By bringing blood pressure under control, Apresol Injection 1 ml gives your body time to stabilise while further medical treatment is provided.
Side effects of Apresol Injection 1 ml
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Apresol Injection 1 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Apresol Injection 1 ml Works

Apresol Injection 1 ml contains hydralazine, a vasodilator that helps lower blood pressure by relaxing and widening blood vessels. Hydralazine works directly on the muscles in the walls of your blood vessels, particularly the arteries, causing them to relax and widen. When these blood vessels relax, they offer less resistance to blood flow, allowing blood to circulate more smoothly throughout your body. As a result, the pressure inside your circulatory system drops quickly and significantly. This reduces the workload on your heart, helping it pump blood more efficiently while preventing long-term damage to your blood vessels and vital organs.
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Alcohol

Unsafe

Avoid alcohol consumption with Apresol Injection 1 ml as it may increase the risk of low blood pressure and cause dizziness, or light-headedness.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before receiving Apresol Injection 1 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Hydralazine may be excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before receiving Apresol Injection 1 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Apresol Injection 1 ml may cause dizziness or light-headedness in some people. Therefore, avoid driving if you feel dizzy or light-headed after receiving Apresol Injection 1 ml.

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Liver

Consult your doctor

If you have a pre-existing history of liver disease, inform your doctor before receiving Apresol Injection 1 ml. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Apresol Injection 1 ml. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Unsafe

Apresol Injection 1 ml is not recommended for children as safety and effectiveness were not established.

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Heart

Caution

Inform your doctor before receiving the Apresol Injection 1 ml if you have a heart disorder. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Elderly patients may require caution and dose adjustments, as Apresol Injection 1 ml may increase the risk of side effects.

What if I have taken an overdose of Apresol Injection 1 ml

If you suspect an overdose, seek emergency medical help right away. An overdose can cause dangerously low blood pressure, a very fast heartbeat, severe headache, or fainting.

Diet & Lifestyle Advise

  • Reduce Salt Intake: Limit your sodium (salt) intake, as excess salt can cause your body to retain water and increase your blood pressure.
  • Limit Alcohol: Avoid or limit alcohol consumption, as it may interact with Apresol Injection 1 ml and cause a sudden drop in blood pressure, leading to dizziness or fainting.
  • Stay Hydrated: Drink enough fluids, but follow your doctor's advice on your daily fluid intake, especially if you have heart or kidney disease.
  • Stay Physically Active: Include light, low-impact activities such as walking in your daily routine, but only after your doctor confirms it is safe for you.
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Have a query?

How Soon It Starts Working

The time required for Apresol Injection 1 ml to start to work: Apresol Injection 1 ml ideally shows its action within 10 to 80 minutes after administration. The time for which the effects of Apresol Injection 1 ml last: The effect of Apresol Injection 1 ml lasts for 71 to 4 hours.

What if you forget to take Apresol Injection 1 ml

Since this medication is typically given by a healthcare professional in a hospital or clinic, it is highly unlikely that you will miss a dose. If you are receiving this treatment on a schedule at home and miss a dose, contact your doctor or pharmacist immediately for guidance. Do not inject a double dose to make up for a missed one.

Storage

• Store Apresol Injection 1 ml at room temperature, ideally between 20°C and 25°C.

Drug Warnings

  • Inspect Before Use: Always check the injection vial before use. The solution should be clear and colourless. Do not use it if you notice any discolouration or visible particles.
  • Stand Up Slowly: Rise slowly from a sitting or lying position to help prevent dizziness, light-headedness, or fainting caused by a sudden drop in blood pressure.
  • Use a New Needle and Syringe: If you are injecting this medicine at home, use a new sterile needle and syringe for every injection and dispose of them safely in a puncture-resistant sharps container.
  • Monitor Blood Pressure and Heart Rate: Check your blood pressure and heart rate regularly as directed by your healthcare team to ensure the medicine is working safely.
  • Inform Healthcare Providers: Tell your dentist, surgeon, or any other healthcare professional that you are receiving Apresol Injection 1 ml before undergoing any medical or dental procedure.

Drug-Drug Interactions

verifiedApollotooltip
  • Other blood pressure-lowering medicines: May cause an excessive drop in blood pressure.
  • Diuretics (water tablets): Can increase the blood pressure-lowering effect, raising the risk of dizziness or fainting.
  • Non-steroidal anti-inflammatory drugs (NSAIDs): May reduce the effectiveness of Apresol Injection 1 ml in lowering blood pressure.
HydralazineTizanidine
Severe

Drug-Drug Interactions

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HydralazineTizanidine
Severe
How does the drug interact with Apresol Injection 1 ml:
Co-administration of Tizanidine with Apresol Injection 1 ml can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Tizanidine and Apresol Injection 1 ml, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid drinking alcohol while receiving Apresol Injection 1 ml, as it can enhance the blood pressure-lowering effect and increase the risk of dizziness, light-headedness, or fainting.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Apresol Injection 1 ml is used to treat Very high blood pressure.
Apresol Injection 1 ml contains Hydralazine, a vasodilator that works by relaxing and widening the walls of blood vessels. Thus, it increases blood and oxygen supply to the heart and reduces blood pressure.
Apresol Injection 1 ml is usually used only briefly to quickly bring down very high blood pressure. After that, your doctor may recommend you take blood pressure tablets.
Apresol Injection 1 ml may cause diarrhoea as a common side effect. However, if the condition persists or worsens, please inform your doctor.
Yes, Apresol Injection 1 ml is often used in hospital settings to treat dangerously high blood pressure during pregnancy, particularly for conditions like preeclampsia. If you are pregnant or planning to become pregnant, talk to your doctor to discuss the benefits and risks of this treatment.
In most cases, Apresol Injection 1 ml is injected by healthcare professionals in a hospital or clinic because it requires close monitoring of your blood pressure and heart rate. If home use is prescribed, you will receive specialised training. Talk to your doctor if you have questions about where you will receive your doses.
Feeling dizzy or lightheaded can happen if your blood pressure drops quickly. Sit or lie down immediately to prevent fainting or falling, and inform your nurse or doctor right away. Talk to your doctor or pharmacist for advice on how to manage these symptoms.
You should avoid alcohol while receiving Apresol Injection 1 ml. Alcohol can widen your blood vessels further, which may cause your blood pressure to drop dangerously low, resulting in severe dizziness or fainting. Talk to your doctor or pharmacist if you have questions about lifestyle restrictions.
Yes, especially with high doses or long-term use, Apresol Injection 1 ml can cause symptoms that mimic lupus, such as joint pain, fever, or a skin rash. These symptoms usually go away after the medication is stopped, but you must report them immediately. Talk to your doctor if you experience any unusual joint pain or rashes.
Apresol Injection 1 ml relaxes blood vessels, which can sometimes trigger a natural reflex in your body that makes your heart beat faster to maintain blood flow. Your medical team will closely monitor your heart rate to ensure it stays within a safe range. Talk to your doctor if you feel your heart racing or pounding.
You should never use the injection if it is discoloured, cloudy, or contains any visible particles. Using a compromised injection can be dangerous. Talk to your doctor or pharmacist immediately to get a replacement vial.

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Country of origin

India

Manufacturer/Marketer address

Survey No.532,Uthiramerur Road,Melavalapettai,Karunguzhi,Madurantakam,Chengalpattu District-603303, Tamilnadu
Other Info - APR0182
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