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compositionComposition:ALECTINIB-150MG
prescription
Prescription Medicine
info
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Alecensa 150 Capsule is used to treat Non-small cell lung cancer (NSCLC), a common form of lung cancer. It contains Alectinib, a type of cancer growth blocker called a tyrosine kinase inhibitor. It works by blocking certain chemical messengers that tell cells to grow. Alecensa 150 Capsule may cause side effects such as diarrhoea, swelling of the hands, muscle pain, tiredness, nausea, vomiting, dizziness, and weakness.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ALECTINIB-150MG

Manufacturer/Marketer :

Roche Diagnostics India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Alecensa 150 Capsule

Alecensa 150 Capsule is a prescription medication used to treat a specific type of advanced non-small cell lung cancer that has spread to other parts of the body. It specifically targets cancer cells that have an abnormal gene signal. By blocking this abnormal pathway, this medication helps slow down or stop the growth and spread of cancer cells.

To get the best results, you must take Alecensa 150 Capsule consistently every day exactly as prescribed by your doctor. This medicine should be taken with food to help your body absorb it properly. Your healthcare team may also recommend specific lifestyle changes, such as staying well-hydrated and protecting your skin from direct sunlight during treatment.

While taking this medicine, you may experience some common side effects like tiredness, constipation, or mild swelling in your hands and feet. However, it is crucial to contact your doctor immediately if you notice serious signs such as severe muscle pain, breathing difficulties, or yellowing of your skin or eyes.

Before starting Alecensa 150 Capsule , talk to your doctor if you have a history of liver disease, kidney problems, or a slow heart rate. Do not take this if you are pregnant, as it can cause serious harm to an unborn baby.

This medication can interact with other drugs and certain supplements, which may change how it works or increase your risk of side effects. Avoid drinking alcohol and smoking while on this treatment, as they can put extra stress on your liver and lungs. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor to discuss the risks and benefits of this treatment.

Uses of Alecensa 150 Capsule

Alecensa 150 Capsule is used to treat a specific type of advanced non-small cell lung cancer. The detailed uses of Alecensa 150 Capsule are as follows:

  • ALK-positive non-small cell lung cancer (NSCLC): Alecensa 150 Capsule helps by targeting and blocking abnormal proteins in cancer cells, which stops them from growing and spreading to other parts of the body, including the brain.

Key Benefits

Alecensa 150 Capsule helps treat certain types of cancer by blocking the signals that promote cancer cell growth. With regular use as prescribed, it helps control tumour progression, treat cancer that has spread to the brain, and offers the convenience of oral therapy.

  • Helps Slow Cancer Growth: By blocking specific pathways involved in cancer cell multiplication, this medicine helps slow tumour growth, reduce the spread of cancer, and support effective disease control.
  • Targets Cancer in the Brain: Because this medicine can cross the blood-brain barrier, it helps treat certain cancers that have spread to the brain or central nervous system, where many other treatments may have limited effectiveness.
  • Convenient Oral Treatment: Available in capsule form, this medicine can be taken at home as directed by your healthcare provider, reducing the need for frequent hospital visits for intravenous chemotherapy while supporting consistent long-term treatment.
Side effects of Alecensa 150 mg Capsule
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.

Directions for Use

  • Alecensa 150 Capsule should be taken with meals or as advised by the doctor.
  • It is usually taken twice daily; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow Alecensa 150 Capsule as a whole with a glass of water.
  • Do not break, crush or chew it.

How Alecensa 150 Capsule Works

Alecensa 150 Capsule contains alectinib, which works by targeting a specific genetic change in lung cancer cells known as an ALK fusion. In this type of lung cancer, an abnormal protein is created that constantly signals the cancer cells to grow and divide rapidly. This medication acts as an inhibitor that binds directly to this abnormal protein. By blocking these signals, it effectively cuts off the instructions that the cancer cells need to survive, causing them to stop multiplying and eventually die.
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Alcohol

Consult your doctor

It is unknown whether Alecensa 150 Capsule interacts with alcohol. Consult your doctor.

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Pregnancy

Unsafe

Alecensa 150 Capsule is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Alecensa 150 Capsule . You should not become pregnant while you are taking Alecensa 150 Capsule for at least one week after your last dose of treatment. Using effective birth control methods while on treatment is suggested.

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Breast Feeding

Unsafe

It is not known whether Alecensa 150 Capsule passes into breast milk. You should not breastfeed during and for 1 week after the treatment with Alecensa 150 Capsule .

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Driving

Unsafe

Alecensa 150 Capsule may cause dizziness, lightheadedness, or fainting in some patients. Therefore, avoid driving or operating machines that require mental concentration until you are not alert.

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Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before taking this medicine. Alecensa 150 Capsule is known to cause hepatotoxicity, which may be fatal. If you have any symptoms such as yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea-coloured) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling very tired while taking Alecensa 150 Capsule , inform your doctor immediately.

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Kidney

Caution

Alecensa 150 Capsule is known to cause kidney impairment. Hence, if you have a pre-existing or a history of kidney diseases, inform your doctor before taking Alecensa 150 Capsule . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Alecensa 150 Capsule is not recommended for children below 18 years as the safety and effectiveness were not established.

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Heart

Caution

Alecensa 150 Capsule should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Alecensa 150 Capsule .

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Geriatrics

Safe if prescribed

Alecensa 150 Capsule is generally considered safe for use in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Alecensa 150 Capsule

If you take more than your prescribed dose, seek immediate medical attention or contact a nearby hospital right away.

Diet & Lifestyle Advise

  • Protect your skin from the sun: This medication can make your skin highly sensitive to sunlight. Wear protective clothing, a wide-brimmed hat, and apply a broad-spectrum sunscreen (SPF 50 or higher) daily while taking this medicine and for at least one week after stopping.
  • Stay well-hydrated: Drink plenty of fluids, especially water, throughout the day. This helps support your kidney function and manages the common side effect of constipation.
  • Eat fibre-rich foods: To prevent or manage constipation, include fibre-rich foods like vegetables, fruits, and whole grains in your daily diet, provided your doctor agrees.
  • Avoid heavy physical strain during muscle pain: If you experience muscle aches, avoid strenuous activities and rest to prevent further muscle strain.
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Have a query?

How Soon It Starts Working

The time required for Alecensa 150 Capsule to start to work: Alecensa 150 Capsule ideally shows its action within 4 to 6 hours after administration. The time for which the effects of Alecensa 150 Capsule last: The effect of Alecensa 150 Capsule lasts for 32 hours.

What if you forget to take Alecensa 150 Capsule

If you miss a dose of Alecensa 150 Capsule , take it as soon as you remember if your next scheduled dose is more than 6 hours away. If your next dose is less than 6 hours away, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one. If you vomit after taking a dose, do not take an extra dose; simply take your next scheduled dose at the normal time.

Storage

•Store Alecensa 150 Capsule capsules at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check your pulse regularly as this medicine can cause a slow heart rate. Inform your doctor if you feel unusually dizzy or weak.
  • Get regular blood tests as scheduled by your healthcare team to monitor your liver function and red blood cell levels.
  • Use reliable birth control during treatment and for at least 1 week after your final dose to prevent pregnancy.
  • Do not breastfeed while taking this medication and for at least 1 week after your final dose.
  • If you experience vision changes, such as blurred vision or seeing flashes of light, avoid driving or operating machinery and contact your doctor.

Drug-Drug Interactions

verifiedApollotooltip
  • Taking this medication with other drugs that slow your heart rate (such as beta-blockers) may increase the risk of an abnormally slow heart rate.
AlectinibLeflunomide
Severe

Drug-Drug Interactions

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AlectinibLeflunomide
Severe
How does the drug interact with Alecensa 150 mg Capsule:
Taking Alecensa 150 mg Capsule with leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between leflunomide and Alecensa 150 mg Capsule, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Alecensa 150 Capsule when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Alecensa 150 Capsule is used to treat Non-small cell lung cancer (NSCLC).
Alecensa 150 Capsule contains Alectinib, which works by stopping the action of an ALK-tyrosine kinase enzyme that causes the multiplication of cancerous cells.
Alecensa 150 Capsule is safe to be taken by a diabetic person. However, take Alecensa 150 Capsule only after consulting with a doctor, as they may adjust the dosing according to your condition.
No, you should always take Alecensa 150 Capsule with food. Taking it with a meal or snack helps your body absorb the medication properly so it can work effectively. Talk to your doctor or pharmacist if you have trouble eating.
If you throw up after taking your dose, do not take an additional dose to make up for it. Just wait and take your next dose at your regular scheduled time. Talk to your doctor or pharmacist if you vomit frequently.
Hair thinning or hair loss is not a commonly reported side effect of this medication. However, if you notice significant hair changes, it is best to discuss this with your healthcare team. Talk to your doctor for personalised advice.
This medication increases your skin's sensitivity to sunlight, which can lead to severe sunburns. You should limit your time in direct sunlight, wear protective clothing, and use a high-SPF sunscreen. Talk to your doctor if you experience any skin rash or severe sunburn.
It is highly recommended to avoid or severely limit alcohol consumption while taking this medication. Alcohol can put extra stress on your liver, which is already working hard to process this treatment. Talk to your doctor about safe lifestyle habits.
Yes, this medication can cause your heart rate to slow down. You should monitor your pulse regularly and report any dizziness, lightheadedness, or fainting to your healthcare provider immediately. Talk to your doctor if you have a history of heart conditions.
No, you must not become pregnant while using this medication as it can cause serious harm to an unborn baby. Both male and female patients should use effective birth control during treatment and for a period after stopping. Talk to your doctor about safe contraceptive options.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Roche Diagnostics India Pvt Ltd, 501 B, Silver Utopia, Cardinal Gracious Road, Chakala Road, Andheri East, Mumbai €“ 400069
Other Info - ALE0167
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