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AFF Tablet is used to lower the high cholesterol or increased cholesterol levels and triglycerides in the blood when a low-fat diet and lifestyle modifications have failed. It contains Atorvastatin, Fenofibrate and Folic Acid. Atorvastatin prevents your body from making 'bad' cholesterol (LDL). At the same time, Fenofibrate works by lowering the levels of triglycerides in your blood. Additionally, they raise 'good' cholesterol (HDL) levels. Folic Acid reduces the levels of a harmful substance (homocysteine), thereby decreasing cholesterol synthesis.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ATORVASTATIN-10MG+FENOFIBRATE-160MG+FOLIC ACID-5MG

Manufacturer/Marketer :

Q Check Pharmaceuticals

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About AFF Tablet

AFF Tablet is a combination prescription medicine used to manage high cholesterol and triglyceride levels in the blood while also regulating specific amino acid levels to support blood vessel health. It is prescribed to reduce the risk of heart-related complications in individuals with mixed lipid disorders. By targeting multiple factors that contribute to arterial blockages, this medicine helps maintain healthier blood circulation.

For this medicine to work effectively, you must take it consistently every day, exactly as directed by your doctor. It is typically taken once daily, and taking it with food can help improve how your body absorbs the medication. To achieve the best possible results, you should combine this treatment with a low-fat diet, regular physical exercise, and other healthy lifestyle choices.

While taking this medicine, some people may experience mild side effects like an upset stomach, nausea, or mild muscle aches. However, you must contact your doctor immediately if you experience severe, unexplained muscle pain, dark-coloured urine, or unusual tiredness. These can be early signs of rare but serious muscle or liver issues that require prompt medical attention.

Before you start taking this medicine, discuss your complete medical history with your doctor, especially if you have a history of liver damage, kidney issues, or gallbladder disease. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding, as it can cause harm to a developing baby.

This medicine can interact with other substances, including certain antibiotics, blood thinners, and alcohol, which can increase your risk of liver damage or severe muscle problems. If you are an older adult or have an underactive thyroid, you should consult your doctor to ensure this medicine is safe for you before starting treatment.

Uses of AFF Tablet

Your doctor may prescribe AFF Tablet to help manage the following conditions:

  • Treatment of combined hyperlipidaemia: It helps reduce high levels of 'bad' cholesterol (LDL) and triglycerides while raising 'good' cholesterol (HDL) in the blood.
  • Reduction of cardiovascular risk: By managing lipid levels, it helps lower the risk of heart attacks, strokes, and other serious heart complications.
  • Management of elevated homocysteine: It helps lower homocysteine levels in the blood, an amino acid that, when elevated, can damage the lining of blood vessels.

Key Benefits

AFF Tablet helps manage different types of fats in the blood as part of a cholesterol-lowering treatment plan. When taken regularly alongside the diet and lifestyle changes recommended by your doctor, it may provide the following benefits:

  • Improves the overall lipid profile: Lowering LDL cholesterol and triglycerides while improving other blood lipid levels helps reduce the buildup of fatty deposits in the arteries and supports healthy blood flow.
  • Supports long-term cardiovascular health: Better control of cholesterol and triglycerides can help reduce cardiovascular risk in people who need lipid-lowering treatment. Folic acid also lowers elevated homocysteine levels, although lowering homocysteine itself has not been consistently shown to reduce heart attack or stroke risk.
  • Simplifies treatment: Combining atorvastatin, fenofibrate, and folic acid in one medicine may reduce the number of separate tablets needed, making the prescribed treatment routine easier to follow.
Side effects of AFF Tablet
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Abnormal liver function requires immediate medical attention. Your doctor may recommend lifestyle modifications along with needed medication.
  • Avoid intake of alcohol as it has a direct impact on liver functioning.
  • Prevent medications like paracetamol, over-the-counter painkillers or those mentioned by your doctor, as they may have issues getting metabolised in your body.
  • If you have overweight issues, losing weight can be a good thing to manage abnormal liver function.
  • Cut down the number of fatty foods that are taken daily.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

Directions for Use

  • AFF Tablet can be taken with or without food as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Swallow AFF Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How AFF Tablet Works

AFF Tablet contains atorvastatin, fenofibrate, and folic acid. These ingredients work in different ways to manage blood lipid levels and homocysteine. Atorvastatin reduces cholesterol production in the liver by blocking an enzyme called HMG-CoA reductase. This also helps the liver remove more LDL cholesterol (often called 'bad' cholesterol) from the blood. Fenofibrate activates a protein called PPAR-alpha, which helps the body break down and clear triglyceride-rich particles from the blood. This mainly lowers triglycerides and can also improve other cholesterol levels. Folic acid is a B vitamin that helps the body process homocysteine, an amino acid naturally present in the blood. This can lower elevated homocysteine levels when folate supplementation is appropriate. Together, these ingredients help improve blood lipid levels while folic acid supports normal homocysteine metabolism.
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Alcohol

Caution

Avoid drinking alcohol while taking AFF Tablet . It can raise triglyceride levels and may increase your risk of liver damage.

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Pregnancy

Caution

Please consult your doctor. There are no well-controlled studies on the effects of AFF Tablet in pregnancy. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

There is no substantial research yet on the use of AFF Tablet in breastfeeding/nursing mothers. Tell your doctor if you are a nursing mother before taking AFF Tablet ; your doctor will decide whether AFF Tablet can be taken by breastfeeding mothers.

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Driving

Not applicable

AFF Tablet usually does not affect your ability to drive or operate machinery. However, do not drive or operate machinery if you feel sleepy or dizzy after taking your medicine.

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Liver

Safe if prescribed

Inform your doctor before taking AFF Tablet if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Safe if prescribed

Inform your doctor before taking AFF Tablet if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

There was limited information about the usage of AFF Tablet in paediatric patients. Please seek medical advice.

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Heart

Caution

AFF Tablet is often prescribed to patients with heart problems to manage high cholesterol and reduce cardiovascular risk. However, it must be taken strictly under medical supervision, as it can affect liver and kidney function and may interact with other heart medications.

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Geriatrics

Caution

Geriatric patients may take AFF Tablet under medical supervision. Age-related liver, kidney, or muscle sensitivity requires regular monitoring and possible dose adjustments.

What if I have taken an overdose of AFF Tablet

If you suspect an overdose or have taken more than your prescribed amount, seek immediate medical attention.

Diet & Lifestyle Advise

  • Eat heart-healthy foods: Eat plenty of vegetables, fruits, whole grains, pulses, nuts, and lean sources of protein while limiting foods high in saturated and trans fats.
  • Reduce added sugars and refined carbohydrates: Limiting sugary drinks, sweets, and highly refined foods can help manage triglyceride levels.
  • Stay physically active: Regular exercise can support cholesterol and triglyceride control. Aim for the type and amount of activity recommended by your doctor based on your health and fitness level.
  • Maintain a healthy weight: If you are overweight, gradual weight loss through balanced eating and regular activity can help improve triglyceride and cholesterol levels.
  • Limit alcohol: Alcohol can raise triglyceride levels, and regular or heavy alcohol intake may also increase the risk of liver-related side effects during treatment. Ask your doctor whether alcohol is appropriate for you.
  • Be cautious with grapefruit: Large amounts of grapefruit or grapefruit juice can increase atorvastatin levels and may increase the risk of side effects. Ask your doctor or pharmacist if grapefruit is a regular part of your diet.
health query

Have a query?

How Soon It Starts Working

The time required for AFF Tablet to start to work: The time required for AFF Tablet to show its action is unknown. The time for which the effects of AFF Tablet last: The duration of action for AFF Tablet is unknown.

What if you forget to take AFF Tablet

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and resume your normal schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store AFF Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Attend regular check-ups: Your doctor may check your cholesterol and triglyceride levels and perform liver function tests to assess how well the treatment is working and monitor for side effects.
  • Report unexplained muscle symptoms: Tell your doctor promptly if you develop unexplained muscle pain, tenderness, weakness, or cramps, particularly if accompanied by fever, unusual tiredness, or dark-coloured urine. The risk of muscle problems can be higher when atorvastatin and fenofibrate are used together.
  • Tell your doctor about kidney or liver problems: Kidney or liver disease can affect whether this medicine is suitable for you and may increase the risk of side effects. Your doctor may perform blood tests before and during treatment.
  • Report symptoms of gallbladder problems: Fenofibrate can increase the risk of gallstones in some people. Tell your doctor if you develop persistent pain in the upper right abdomen, particularly with nausea or vomiting.
  • Check before starting new medicines: Some medicines can interact with atorvastatin or fenofibrate and increase the risk of muscle, liver, or bleeding-related side effects. Tell your doctor or pharmacist about all prescription medicines, over-the-counter medicines, and supplements you take.
  • Pregnancy and breastfeeding: Tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding so your lipid-lowering treatment can be reviewed appropriately.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood-thinning medicines (e.g. warfarin): Fenofibrate may increase the effect of warfarin and raise the risk of bleeding. Your doctor may monitor your blood clotting more closely and adjust the warfarin dose if needed.
  • Other cholesterol-lowering medicines (e.g. gemfibrozil or other fibrates): Using these with AFF Tablet may increase the risk of muscle-related side effects and is generally avoided unless specifically advised by your doctor.
  • Certain antibiotics (e.g. clarithromycin or erythromycin): These medicines can increase atorvastatin levels in the blood and may increase the risk of muscle-related side effects. Your doctor may adjust your treatment while you are taking them.
  • Certain antifungal medicines (e.g. itraconazole, ketoconazole, or posaconazole): These medicines can increase atorvastatin levels and the risk of side effects. Your doctor may adjust or temporarily change your treatment.
  • Certain antiviral medicines used for HIV or hepatitis C: Some antiviral medicines can significantly increase atorvastatin levels. Your doctor will check whether the combination is suitable and may adjust your medicines.
  • Ciclosporin: Taking ciclosporin with atorvastatin and fenofibrate can increase the risk of muscle-related side effects and may require an alternative treatment or close monitoring.
  • Colchicine: Using colchicine with atorvastatin or fenofibrate may increase the risk of muscle problems. Tell your doctor promptly if you develop unexplained muscle pain or weakness.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit or grapefruit juice: Large amounts can increase atorvastatin levels in the blood and may increase the risk of side effects. Ask your doctor or pharmacist about an appropriate amount if you regularly consume grapefruit.
  • Alcohol: Regular or heavy alcohol consumption may increase triglyceride levels and the risk of liver-related side effects. Discuss your alcohol intake with your doctor.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTILIPEMICS]

FAQs

AFF Tablet is used to treat High Cholesterol and High Triglycerides.
AFF Tablet contains Atorvastatin, Fenofibrate and Folic Acid. Atorvastatin prevents your body from making "bad" cholesterol (LDL), while Fenofibrate works by lowering the levels of triglycerides in your blood. Additionally, they raise "good" cholesterol (HDL) levels. Folic Acid reduces the levels of a harmful substance (homocysteine), thereby decreasing cholesterol synthesis.
When you have more than your body requirements, cholesterol can result in plaque to build-up in your blood vessels. This thick, hard plaque can block your arteries like a blocked pipe. Decreased blood flow can cause heart attack and stroke.
Take the missed dose as soon as possible, or skip to the next dose if it's been too late. Never try to take a double dose to make up for the missed dose.
AFF Tablet contains Atorvastatin which can raise your blood sugar a little. If you already have type 2 diabetes, please consult your doctor. Your doctor may adjust the dosage of AFF Tablet .
It is best to avoid or strictly limit alcohol while taking this medicine. Alcohol increases your risk of liver damage and can also raise triglyceride levels, making the treatment less effective. Talk to your doctor about your alcohol consumption.
You can take this medicine at any time of day, but it is best to take it at the same time every day to maintain a steady level in your body. Some doctors recommend taking it with your evening meal to aid absorption. Talk to your doctor for specific advice.
If you experience unexplained muscle pain, tenderness, or weakness, contact your doctor immediately. This is especially urgent if the pain is accompanied by a fever or general tiredness. Talk to your doctor before making any changes to your therapy.
No, you should not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding. It can cause serious harm to a developing baby. Talk to your doctor immediately about alternative options if you suspect you are pregnant.
Yes, this medicine works best when combined with a low-fat, low-cholesterol diet and regular physical activity. Taking the medicine without dietary changes will greatly reduce its effectiveness. Talk to your doctor or a dietitian for personalised dietary advice.
In rare cases, this medicine can affect liver function. Your doctor will perform blood tests to monitor your liver health before and during your treatment. Contact your doctor immediately if you notice yellowing of your skin or eyes, dark urine, or severe stomach pain. Talk to your doctor if you have concerns.
Certain supplements, especially those containing niacin or other lipid-altering ingredients, can interact with this medicine and increase the risk of side effects. Always inform your pharmacist or doctor about all supplements you take. Talk to your doctor before starting any new supplement.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Health Service (NHS). Atorvastatin - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Fenofibrate Patient Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. National Center for Biotechnology Information (NCBI). Nbk430779 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  5. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  6. National Center for Biotechnology Information (NCBI). Atorvastatin + Fenofibrate + Folic Acid Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  7. MIMS Drug Reference Compendium. Atorvastatin Monograph. Singapore: MIMS; 2025. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

No 145 Q Square, Sakthi Nagar, 7th Street Ganesh Avenue, Porur, Chennai - 600116.
Other Info - AFF0007
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