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AdvaUD Tablet 15's is used to treat primary biliary cholangitis (a liver autoimmune disease), cholestatic liver problems, and fatty liver disease. It contains Nor-Ursodeoxycholic acid (norUDCA), which helps increase healthy bile flow, reduces swelling and irritation in the bile ducts, slows liver scarring (fibrosis), and protects liver cells. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding and about all the medications you are taking and pre-existing medical conditions.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About AdvaUD Tablet 15's

AdvaUD Tablet 15's is an oral medicine prescribed to treat chronic liver conditions, particularly those involving inflamed, damaged, or blocked bile ducts. It works by improving the overall flow of bile and protecting liver cells from damage caused by the buildup of toxic bile acids. Your doctor may prescribe this medicine to help manage inflammation and prevent long-term liver scarring.

For the best results, you must take AdvaUD Tablet 15's regularly and consistently at the same times each day. It is usually taken with food or a light snack to help your body absorb it properly and to prevent stomach upset. Making simple dietary changes, such as reducing your intake of greasy or fatty foods, can also support your treatment and ease the strain on your digestive system.

Most patients tolerate this medicine well, though some may experience mild side effects like loose stools or temporary stomach discomfort. However, you should contact your doctor immediately if you experience severe abdominal pain, persistent yellowing of your skin or eyes, or intense itching. Always consult your healthcare provider if you notice any unusual or worsening symptoms.

Before you begin taking AdvaUD Tablet 15's, tell your doctor if you have other medical issues, especially severe liver failure, gallbladder inflammation, or blockages in your bile ducts. Do not take this medicine if you have a complete obstruction of your bile ducts, as increasing bile flow in a completely blocked system can cause serious complications.

This medicine can interact with certain other products, such as antacids containing aluminum or cholesterol-lowering drugs, which can stop your body from absorbing it. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, discuss the specific risks and benefits with your doctor before starting treatment.

Uses of AdvaUD Tablet 15's

AdvaUD Tablet 15's is used to treat liver disorders. The detailed uses of AdvaUD Tablet 15's are as follows:

  • Primary Sclerosing Cholangitis (PSC): AdvaUD Tablet 15's helps reduce inflammation and scarring in the bile ducts, allowing bile to flow more freely and preventing damage to liver tissues.
  • Nonalcoholic Fatty Liver Disease (NAFLD): In certain cases, this medicine is used to help decrease liver cell inflammation and support overall liver function.
  • Chronic Cholestatic Liver Disorders: AdvaUD Tablet 15's protects liver cells by diluting and flushing out toxic bile acids that build up during chronic liver conditions.

Key Benefits

AdvaUD Tablet 15's provides important benefits to help you manage your chronic liver condition and feel better in your day-to-day life.
Benefits may include:

  • By promoting healthy bile flow, this medicine helps reduce the accumulation of bile salts under the skin, which is a major cause of severe, uncomfortable itching.
  • It replaces toxic, damaging bile acids with safer, protective bile acids, helping to slow down liver damage and preserve long-term liver health.
  • Easing the inflammation in your liver and bile ducts can help reduce the chronic fatigue and right-sided abdominal discomfort often associated with liver issues.

Directions for Use

  • AdvaUD Tablet 15's can be taken with food to prevent stomach upset or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow AdvaUD Tablet 15's as a whole with a glass of water.
  • Do not chew, crush, or break it.

How AdvaUD Tablet 15's Works

AdvaUD Tablet 15's is a modified bile acid that works directly within your liver and bile ducts. Unlike normal bile acids, it resists being quickly broken down or altered by the liver. This unique property allows it to pass repeatedly between the liver and the gallbladder in a process that flushes the bile ducts. As it circulates, AdvaUD Tablet 15's stimulates the secretion of a watery, bicarbonate-rich bile. This dilutes the highly concentrated and toxic bile acids that have built up due to inflammation or blockage. By neutralising these harmful acids and washing them away, the medicine reduces inflammation, prevents cell damage, and protects the delicate tissues of your bile ducts from scarring.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking AdvaUD Tablet 15's as it may cause increased dizziness and liver damage.

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Pregnancy

Consult your doctor

Please consult your doctor if you have any concerns regarding this. AdvaUD Tablet 15's should be used during pregnancy only if absolutely necessary.

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Breast Feeding

Consult your doctor

Consult your doctor before taking AdvaUD Tablet 15's; your doctor will decide whether breastfeeding mothers can take AdvaUD Tablet 15's or not.

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Driving

Consult your doctor

It is unknown whether AdvaUD Tablet 15's affects your ability to drive or operate. Please consult your physician.

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Liver

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Children

Consult your doctor

AdvaUD Tablet 15's should be given to children only if prescribed by the doctor/paediatrician.

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Heart

Consult your doctor

Please consult your physician if you have any concerns regarding the use of AdvaUD Tablet 15's in cardiac patients.

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Geriatrics

Consult your doctor

Please consult your physician if you have any concerns regarding the use of AdvaUD Tablet 15's in elderly patients.

What if I have taken an overdose of AdvaUD Tablet 15's

If you take too much of this medicine, seek immediate medical attention or call a poison control centre. Symptoms of an overdose may include severe diarrhoea or stomach pain.

Diet & Lifestyle Advise

  • Follow a low-fat diet: Reducing your intake of saturated fats and fried foods helps ease the workload on your liver and gallbladder, reducing symptoms like bloating and nausea.
  • Stay well-hydrated: Drink plenty of water throughout the day to support your kidneys and help your liver flush out waste products.
  • Avoid alcohol entirely: Alcohol is directly toxic to liver cells and can accelerate liver damage, making your treatment less effective.
  • Eat smaller, more frequent meals: Eating small portions throughout the day makes it easier for your digestive system to process fats and bile.
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How Soon It Starts Working

  • The time required for AdvaUD Tablet 15's to start working: The time required for AdvaUD Tablet 15's to show its effect is unknown.
  • The time for which the effects of AdvaUD Tablet 15's last: The duration of action for AdvaUD Tablet 15's is unknown.

What if you forget to take AdvaUD Tablet 15's

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store AdvaUD Tablet 15's tablets or capsules at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Check the medicine: Inspect your tablets or capsules before taking them; do not take them if the packaging is damaged or if the pills look discoloured.
  • Do not stop suddenly: Do not stop taking AdvaUD Tablet 15's suddenly, even if you feel completely healthy, as your liver enzymes and bile flow can worsen quickly without it.
  • Attend monitoring appointments: Keep all appointments for blood tests so your doctor can monitor liver enzymes such as ALP, GGT, and ALT, assess your response to treatment, and adjust your treatment plan safely.
  • Inform your healthcare providers: Inform your dentist and any other doctors you visit that you are taking this medicine before undergoing any medical procedures.
  • When to see a doctor: Seek prompt medical attention if you develop severe or persistent upper-right abdominal pain, worsening yellowing of the skin or eyes, unusually dark urine, severe or persistent diarrhoea, or any new or rapidly worsening symptoms while taking this medicine.

verifiedApollotooltip
  • Bile acid sequestrants (e.g., cholestyramine or colestipol): These medicines bind to AdvaUD Tablet 15's in your stomach and prevent your body from absorbing it. Take AdvaUD Tablet 15's at least 2 hours before or 4 to 6 hours after taking these medications.
  • Aluminium-containing antacids: These can interfere with how well your body absorbs this medicine. Avoid taking them at the same time.

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verifiedApollotooltip

No clinically significant food interactions are known with AdvaUD Tablet 15's when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[BILE ACID SEQUESTRANTS]

FAQs

Avoid taking aluminium-containing antacids at the same time as AdvaUD Tablet 15's because they may reduce its absorption. If you need to take an aluminium-containing antacid, separate it from AdvaUD Tablet 15's by at least 2 hours. Ask your doctor or pharmacist if you are unsure which antacids are suitable.
No, you should avoid alcohol. Alcohol puts extra stress on your liver and can worsen the liver damage that AdvaUD Tablet 15's is trying to treat. Talk to your doctor if you need help cutting back on alcohol.
It is highly recommended to take this medicine with food or a snack. This helps protect your stomach from irritation and assists your body in absorbing the medicine effectively. Talk to your doctor or pharmacist for specific advice.
It can take several weeks or even months of consistent daily use before your liver enzymes show improvement on blood tests. Continue taking it as prescribed, and talk to your doctor to monitor your progress.
No, you must not stop taking this medicine without your doctor's permission. Stopping the medicine can cause your bile levels to rise again, bringing back symptoms and potential liver damage. Talk to your doctor first.
The safety of this medicine during pregnancy is not fully established. If you are pregnant, planning to become pregnant, or breastfeeding, you must talk to your doctor before starting or continuing this medicine.
Mild loose stools can happen when starting this medicine. However, if you develop severe, persistent, or watery diarrhoea, stop taking the medicine and talk to your doctor or pharmacist immediately to prevent dehydration.
No, you should swallow the tablets or capsules whole with water. Crushing or chewing them can ruin the special coating or release mechanism and cause a very bitter taste. Talk to your pharmacist if you have trouble swallowing pills.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase Iii, New Delhi - 110020.
Other Info - ADV0169
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