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  3. Adacord 40 mg Pfs Injection 0.8 ml

Adacord 40 mg Pfs Injection 0.8 ml, Pack of 1
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Santoshini Reddy G , M Pharmacy

Adacord 40 mg Pfs Injection 0.8 ml is used to help reduce signs and symptoms of autoimmune disorders such as Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn's disease, Uveitis and Ulcerative colitis. It consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

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Composition :

ADALIMUMAB-40MG

Manufacturer/Marketer :

CONCORD DRUGS LTD

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Adacord 40 mg Pfs Injection 0.8 ml

Adacord 40 mg Pfs Injection 0.8 ml belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors that help reduce signs and symptoms of autoimmune disorders. It is primarily used in the treatment of rheumatoid arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, plaque psoriasis, and psoriatic arthritis. This medicine is also used in the treatment of Crohn’s disease, ulcerative colitis, hidradenitis suppurativa, and uveitis.

Adacord 40 mg Pfs Injection 0.8 ml consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

Adacord 40 mg Pfs Injection 0.8 ml may cause certain side effects such as nausea, headache, back pain, upper respiratory tract infections, vision problems, dizziness, pale skin, numbness, chest pain, rash, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if these side effects persist for longer, please consult your doctor on priority. Adacord 40 mg Pfs Injection 0.8 ml is a parenteral medicine. It will be administered by a trained healthcare doctor. Hence, do not self-administer. Your physician will decide the dose and duration of the medicine based on the type and severity of the condition.

Adacord 40 mg Pfs Injection 0.8 ml should be avoided if you are allergic to any of its components.  Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, hepatitis B virus infection, heart failure, liver, heart, or kidney diseases, or a weak immune system, as it can worsen your health condition. Adacord 40 mg Pfs Injection 0.8 ml may cause dizziness, so drive only if you are alert and focused. Adacord 40 mg Pfs Injection 0.8 ml should not be given to children under two years of age as safety has not been established. Consult the doctor if you are pregnant or breastfeeding.

Uses of Adacord 40 mg Pfs Injection 0.8 ml

Adacord 40 mg Pfs Injection 0.8 ml is used in the treatment of autoimmune inflammatory diseases. The detailed uses of Adacord 40 mg Pfs Injection 0.8 ml are as follows:<br/>• Treatment of Rheumatoid arthritis (RA): Adacord 40 mg Pfs Injection 0.8 ml reduces inflammation, joint pain, and stiffness in adults with moderate to severe RA, improving mobility and quality of life.<br/>• Treatment of Juvenile idiopathic arthritis (JIA): Adacord 40 mg Pfs Injection 0.8 ml is used in children to control inflammation, relieve joint symptoms, and support normal growth and development.<br/>• Treatment of Crohn’s disease: Adacord 40 mg Pfs Injection 0.8 ml treats moderate to severe Crohn’s disease in adults and children by reducing intestinal inflammation when other treatments fail.<br/>• Treatment of Ulcerative colitis: Adacord 40 mg Pfs Injection 0.8 ml is indicated for adults and children with moderate to severe ulcerative colitis who are unresponsive to conventional therapy.<br/>• Treatment of Ankylosing spondylitis: Adacord 40 mg Pfs Injection 0.8 ml helps manage chronic back pain and stiffness by reducing spinal inflammation in adults.<br/>• Treatment of Psoriatic arthritis: Adacord 40 mg Pfs Injection 0.8 ml improves joint and skin symptoms in adults by decreasing swelling, pain, and the formation of psoriatic skin lesions.<br/>• Treatment of Hidradenitis suppurativa: Adacord 40 mg Pfs Injection 0.8 ml is used in adults and adolescents to reduce painful lumps and inflammation in areas like the armpits and groin.<br/>• Treatment of Uveitis: Adacord 40 mg Pfs Injection 0.8 ml treats non-infectious uveitis in adults and children by lowering eye inflammation and helping preserve vision.<br/>• Treatment of Chronic plaque psoriasis: Adacord 40 mg Pfs Injection 0.8 ml is used in adults with moderate to severe plaque psoriasis to reduce red, scaly patches and improve skin appearance.<br/>

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Adacord 40 mg Pfs Injection 0.8 ml will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Adacord 40 mg Pfs Injection 0.8 ml consists of Adalimumab, which belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain, redness, and inflammation (swelling) caused by various autoimmune diseases.

How Adacord 40 mg Pfs Injection 0.8 ml Works

Adacord 40 mg Pfs Injection 0.8 ml consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Adacord 40 mg Pfs Injection 0.8 ml out of the sight and reach of children.
• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Adacord 40 mg Pfs Injection 0.8 ml
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

What if I have taken an overdose of Adacord 40 mg Pfs Injection 0.8 ml

Since Adacord 40 mg Pfs Injection 0.8 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Adacord 40 mg Pfs Injection 0.8 ml should be avoided if allergic to it or any other components present. Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, hepatitis B virus infection, heart failure, liver, heart or kidney diseases, weak immune system, multiple sclerosis (nerve and muscle disease), or diabetes as it can worsen your health condition. Do not take live vaccines while being treated with Adacord 40 mg Pfs Injection 0.8 ml to prevent any serious consequences. Adacord 40 mg Pfs Injection 0.8 ml is not recommended for use in children below two years of age as safety and efficacy are not established. This medicine is not recommended for patients suffering from sepsis as it can worsen the condition.

Drug-Drug Interactions

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AdalimumabMitoxantrone
Severe
AdalimumabCapecitabine
Severe

Drug-Drug Interactions

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AdalimumabMitoxantrone
Severe
How does the drug interact with Adacord 40 mg Pfs Injection 0.8 ml:
Using Adacord 40 mg Pfs Injection 0.8 ml together with mitoxantrone may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Mitoxantrone and Adacord 40 mg Pfs Injection 0.8 ml, but it can be taken if prescribed by a doctor. However, if you experience symptoms like stomach pain, ongoing fever, excessive sweating at night, unexplained weight loss, infection, fever, chills, diarrhoea, a sore throat, muscle pain, difficulty breathing, or pain or discomfort when urinating. Do not discontinue any medications without first consulting a doctor.
AdalimumabCapecitabine
Severe
How does the drug interact with Adacord 40 mg Pfs Injection 0.8 ml:
Co-administration of Capecitabine is taken with Adacord 40 mg Pfs Injection 0.8 ml, which may increase the risk or severity of infections.

How to manage the interaction:
There may be a possibility of interaction between Capecitabine and Adacord 40 mg Pfs Injection 0.8 ml, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include an enlarged spleen or liver, stomach pain, ongoing fever, excessive sweating at night, unexplained weight loss, complications, infection, fever, chills, diarrhea, a sore throat, muscle aches, difficulty breathing, or pain or discomfort while urinating. Do not stop using any medications without a doctor's advice.
AdalimumabDexamethasone
Severe
How does the drug interact with Adacord 40 mg Pfs Injection 0.8 ml:
When Dexamethasone and Adacord 40 mg Pfs Injection 0.8 ml are taken together, may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Dexamethasone and Adacord 40 mg Pfs Injection 0.8 ml, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include a serious infection, sepsis, fever, chills, diarrhoea, a sore throat, muscle pain, difficulty breathing, losing weight, or experiencing pain or burning when you urinate. Do not stop using any medications without talking to a doctor.
AdalimumabDasatinib
Severe
How does the drug interact with Adacord 40 mg Pfs Injection 0.8 ml:
Using Adacord 40 mg Pfs Injection 0.8 ml together with Dasatinib may increase the risk of infections.

How to manage the interaction:
There may be a possibility of interaction between Dasatinib and Adacord 40 mg Pfs Injection 0.8 ml, but it can be taken if prescribed by a doctor. If you experience fever, a sore throat, muscle pain, difficulty breathing, pain, or burning when you urinate, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AdalimumabBaricitinib
Severe
How does the drug interact with Adacord 40 mg Pfs Injection 0.8 ml:
Coadministration of baricitinib and Adacord 40 mg Pfs Injection 0.8 ml can raise your risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Adacord 40 mg Pfs Injection 0.8 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
AdalimumabEtanercept
Severe
How does the drug interact with Adacord 40 mg Pfs Injection 0.8 ml:
Using Adacord 40 mg Pfs Injection 0.8 ml together with etanercept may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Etanercept and Adacord 40 mg Pfs Injection 0.8 ml, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AdalimumabGanciclovir
Severe
How does the drug interact with Adacord 40 mg Pfs Injection 0.8 ml:
Using ganciclovir together with Adacord 40 mg Pfs Injection 0.8 ml may increase the risk of serious infections.

How to manage the interaction:
Taking ganciclovir with Adacord 40 mg Pfs Injection 0.8 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AdalimumabMelphalan
Severe
How does the drug interact with Adacord 40 mg Pfs Injection 0.8 ml:
Co-administration of Adacord 40 mg Pfs Injection 0.8 ml with Melphalan together can increase the risk and severity of infection.

How to manage the interaction:
Although taking Melphalan and Adacord 40 mg Pfs Injection 0.8 ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
AdalimumabRuxolitinib
Severe
How does the drug interact with Adacord 40 mg Pfs Injection 0.8 ml:
Taking Ruxolitinib together with Adacord 40 mg Pfs Injection 0.8 ml may increase the risk of infections.

How to manage the interaction:
Although taking Ruxolitinib and Adacord 40 mg Pfs Injection 0.8 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
AdalimumabFludrocortisone
Severe
How does the drug interact with Adacord 40 mg Pfs Injection 0.8 ml:
Co-administration of Adacord 40 mg Pfs Injection 0.8 ml with fludrocortisone can increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction between Fludrocortisone and Adacord 40 mg Pfs Injection 0.8 ml, it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, or pain while urinating contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • Stay hydrated; drink plenty of water.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Adacord 40 mg Pfs Injection 0.8 ml Substitute

Substitutes safety advice
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Adacord 40 mg Pfs Injection 0.8 ml. Please consult the doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Adacord 40 mg Pfs Injection 0.8 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Adacord 40 mg Pfs Injection 0.8 ml.

bannner image

Driving

Caution

Adacord 40 mg Pfs Injection 0.8 ml will be administered in the hospital setting. Hence, driving is not recommended.

bannner image

Liver

Caution

Adacord 40 mg Pfs Injection 0.8 ml should be used with caution if you have liver disease. Dose adjustment may be needed in patients with liver impairment.

bannner image

Kidney

Caution

Adacord 40 mg Pfs Injection 0.8 ml should be used with caution if you have kidney disease. Dose adjustment may be needed in patients with liver impairment.

bannner image

Children

Caution

Adacord 40 mg Pfs Injection 0.8 ml is not recommended in children below two years of age as safety and efficacy are not established. In children above two years of age, it will be administered by the pediatrician. Adacord 40 mg Pfs Injection 0.8 ml is used in children only for the treatment of juvenile idiopathic arthritis, paediatric Crohn’s disease, and uveitis.

FAQs

Adacord 40 mg Pfs Injection 0.8 ml is used to treat Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn’s disease, Uveitis and Ulcerative colitis.

Adacord 40 mg Pfs Injection 0.8 ml contains Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive.

Adacord 40 mg Pfs Injection 0.8 ml affects your immune system and makes you more susceptible to infections. Hence, it is not recommended in people with active infections like tuberculosis or abnormal liver enzymes. Adacord 40 mg Pfs Injection 0.8 ml can also increase the risk of developing cancers; hence, informing your doctor if you have a history of any cancer is essential.

Adacord 40 mg Pfs Injection 0.8 ml is an antirheumatic medicine that belongs to the TNF (tumor necrosis factor) inhibitor class. It contains the active ingredient Adalimumab.

Treatment with Adacord 40 mg Pfs Injection 0.8 ml can help reduce inflammation, pain, redness, and swelling associated with various autoimmune disorders.

Adacord 40 mg Pfs Injection 0.8 ml which contains Adalimumab, can weaken your immune system. Since it affects the immune system, it may increase your risk of developing infections. It is important to follow your doctor's advice and inform them if you have any existing infections or health concerns before starting treatment.

Adacord 40 mg Pfs Injection 0.8 ml can be used alongside other arthritis medicines such as methotrexate, prednisolone, naproxen, ibuprofen, and paracetamol. However, Adacord 40 mg Pfs Injection 0.8 ml should not be used with other biological disease-modifying antirheumatic drugs (bDMARDs).

Adacord 40 mg Pfs Injection 0.8 ml should be stopped before surgery. It can be resumed after the operation, once the wound has healed and there is no infection, as determined by your surgeon and rheumatologist.

Adacord 40 mg Pfs Injection 0.8 ml causes side effects such as rash, headache, sinusitis, upper respiratory infections, fever, and application site reactions. Therefore, please contact a doctor if these do not reduce and persist for longer durations.

Country of origin

India

Manufacturer/Marketer address

Survey No: 249, Brahmanapally(V), Hayathnagar (M), R.R.District, Hyderabad, Telangana, India – 501511
Other Info - ADA0074

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Author Details

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 9:22 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/125057s410lbl.pdf
  2. https://medlineplus.gov/druginfo/meds/a603010.html
  3. https://go.drugbank.com/drugs/DB00051
  4. https://reference.medscape.com/drug/amjevita-humira-adalimumab-343187
  5. https://www.nhs.uk/medicines/adalimumab/
  6. https://www.humira.com/

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