Yes, there are several effective medications that can help improve enlarged pores and reduce pimple marks, though results take time and regular use. Doctors commonly recommend topical treatments like Adapalene or Tretinoin, which help renew the skin, unclog pores, and gradually improve texture, as well as Niacinamide to reduce oiliness and lighten marks, and Azelaic Acid to fade dark spots and control acne. Using sunscreen daily is very important, as sun exposure can worsen marks and slow healing. While these treatments can significantly improve skin appearance, pores cannot be completely closed, but they can look smaller with proper care. For deeper scars or stubborn marks, dermatological procedures may be advised. Consistency, gentle skin care, and medical guidance are key to achieving the best results.