Chest pain that comes and goes may be caused by several conditions, including acid reflux, muscle strain, anxiety, or sometimes heart-related problems. It is important to note whether it occurs during physical activity or is associated with breathlessness, sweating, or pain that spreads to the arm or jaw. Because some causes can be serious, it is best to consult a doctor for a proper evaluation and tests. Seek medical care urgently if the pain becomes severe, persistent, or is associated with difficulty in breathing.