Yes, you can usually take Rifagut 550 (Rifaximin) for IBS-D (irritable bowel syndrome with diarrhoea) while on Apixator 2.5 (Apixaban), as Rifaximin works mainly in the gut and is minimally absorbed into the bloodstream. There is no known interaction between the two medicines. However, since Apixaban is a blood thinner, it is important to use any additional medication under medical supervision. Please consult your doctor before starting Rifaximin to ensure it is appropriate for your condition.