Severe tooth pain can happen because of tooth decay, cavity, gum infection, wisdom tooth problems, sensitivity, or infection around the tooth root. The pain may become worse while eating, drinking hot or cold items, or lying down. Pain medicines may provide temporary relief, but the underlying dental problem usually still needs proper treatment, such as cleaning, filling, root canal treatment, or treatment for gum infection. Medicines commonly used for temporary tooth pain relief may include paracetamol or anti-inflammatory pain medicines, but the right choice depends on your age, stomach health, kidney function, allergies, and other medical conditions. Avoid taking repeated painkillers or antibiotics without proper dental advice because this may only mask the pain without treating the actual cause. Warm saltwater rinses, maintaining oral hygiene, avoiding very cold or sugary foods, and not chewing on the painful side may help reduce irritation. Do not place painkiller tablets directly on the tooth or gums because this may burn the tissues. Consult a dentist soon if swelling develops, fever occurs, pus appears, or the pain becomes severe enough to disturb sleep or eating.