It is quite common for permethrin (the active ingredient in your current lotion) to temporarily cause burning, stinging, or increased itching as the mites die. However, if the irritation is painful, you have alternative options. Crotamiton lotion is an excellent alternative because it kills the mites while actively soothing itchiness. Another highly effective and gentle option is sulfur ointment, which is very mild on sensitive skin. Alternatively, your doctor might suggest oral ivermectin to avoid applying creams entirely. Please consult your healthcare provider before switching so they can advise on the correct application and perhaps prescribe a mild steroid cream to calm your current skin irritation.