Netarsudil
About Netarsudil
Netarsudil is a specialized ophthalmic solution used to lower high pressure inside the eye in patients with open-angle glaucoma or ocular hypertension. Keeping your eye pressure within a normal range is crucial for preventing progressive damage to your optic nerve and protecting your long-term sight. Your doctor will likely prescribe this medication to help keep your eyes healthy and functional.
To get the best results, you must use Netarsudil consistently, usually once a day in the evening as directed by your eye specialist. Because Netarsudil is administered directly to the eye, it can be used without regard to food or meal times. Alongside your medication, simple lifestyle adjustments—such as avoiding head-down positions and eating a diet rich in eye-supporting nutrients—can support your overall eye health.
While using Netarsudil, some people experience temporary eye redness, a mild burning sensation, or small, harmless deposits on the surface of the eye. Most of these effects are mild, but you must contact your doctor immediately if you experience severe eye pain, sudden vision changes, or signs of an eye infection. Regular monitoring by your eye care professional ensures that these side effects are managed safely.
Do not take this if you are allergic to any of the ingredients in this ophthalmic solution. Before starting Netarsudil, tell your doctor if you have a history of corneal disease, severe dry eyes, or other active eye conditions that might require close monitoring during your treatment.
Inform your doctor about any other eye drops, prescription medications, or over-the-counter products you use to prevent unwanted interactions. If you are pregnant, planning to become pregnant, or breastfeeding, you should consult your doctor to discuss whether this treatment is safe for your baby.
Uses of Netarsudil
Medicinal Benefits
Netarsudil helps lower increased pressure inside the eye, protecting the optic nerve and supporting long-term vision health. By maintaining healthy eye pressure, it helps reduce the risk of vision loss associated with glaucoma and ocular hypertension.
Benefits may include:
- Helps lower and maintain healthy intraocular (eye) pressure.
- Supports protection of the optic nerve from pressure-related damage.
- Reduces the risk of vision loss associated with glaucoma and ocular hypertension.
- Provides consistent eye pressure control with convenient once-daily dosing.
- Supports long-term eye health and preservation of vision.
- Works locally within the eye, helping minimise the risk of body-wide side effects.
Directions for Use
- Netarsudil is for ophthalmic (for eye) use only.
- It is recommended to apply one drop of Netarsudil once daily in the evening or as advised by your doctor.
- Check the label for directions before using this medication.
- Lie down and tilt your head backward. Gently pull your lower eyelid with your index finger to form a pocket. Instil the prescribed number of drops into the pocket. Close your eyes for 1-2 minutes.
- Avoid touching the container tip to the eye or eyelids to prevent contamination.
Storage
Side Effects of Netarsudil
Common Side Effects (Usually mild):
- Redness in the white of the eyes or inner eyelids
- Mild eye irritation, burning, or stinging upon application
- Small broken blood vessels on the surface of the eye
- Temporary blurred vision immediately after applying the drops
Serious Side Effects (Call a doctor right away):
- Severe eye pain, swelling, or extreme sensitivity to light
- Sudden, unexpected changes in your vision or loss of sight
- Signs of an eye infection, such as discharge, crusting, or worsening redness
- Severe allergic reactions, including swelling of the face, tongue, or throat, dizziness, and difficulty breathing
Medicines Containing this Salt
View AllDrug Warnings
- Inspect the solution before use: Check the eye drops before each use. Do not use them if the solution appears cloudy, discolored, or contains visible particles.
- Avoid contaminating the dropper: Never allow the dropper tip to touch your eye, eyelid, fingers, skin, or any other surface to help keep the solution sterile.
- Report eye problems promptly: Contact your doctor immediately if you develop an eye injury, an eye infection, or need to undergo eye surgery, as your treatment may need to be reviewed.
- Remove soft contact lenses before application: Do not wear soft contact lenses while applying these eye drops. Follow your doctor's instructions on when it is safe to reinsert your lenses after use.
- Use caution if vision is blurred: Avoid driving, operating machinery, or performing tasks that require clear vision until your eyesight has returned to normal after applying the drops.
Drug Interactions
- Other eye drops or glaucoma medicines: Using these alongside Netarsudil may increase eye irritation or affect how Netarsudils work. Always leave at least 5 minutes between different eye drops.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is unknown if alcohol interacts with Netarsudil. Please consult a doctor.
Pregnancy
cautionPlease consult your doctor if you have any concerns regarding this. Your doctor will decide if Netarsudil can be used by pregnant women or not.
Breast Feeding
cautionPlease consult your doctor if you have any concerns regarding this. Your doctor will decide if Netarsudil can be used by breastfeeding women or not.
Driving
cautionNetarsudil might cause blurred vision. So, avoid driving or operating machinery until your vision is clear.
Liver
cautionPlease consult your doctor if you have any concerns regarding the usage of Netarsudil in patients with liver impairment.
Kidney
cautionPlease consult your doctor if you have any concerns regarding the usage of Netarsudil in patients with kidney impairment.
Children
unsafeNetarsudil is not recommended for children below 18 years as safety and effectiveness have not been established.
Habit Forming
Diet & Lifestyle Advise
- Exercise with caution: Regular, moderate aerobic exercise like walking can help lower eye pressure. However, avoid exercises that require you to be upside down, such as certain yoga poses, as these can increase pressure in the eyes.
- Limit caffeine: Drinking large amounts of caffeine in a short period can temporarily raise your eye pressure. It is best to consume caffeinated beverages in moderation.
- Drink fluids gradually: To prevent sudden spikes in eye pressure, sip water and other fluids slowly throughout the day rather than drinking large quantities all at once.
- Wear protective eyewear: Protect your eyes from physical injury during sports, home repairs, or gardening, as eye trauma can worsen pressure problems. Wear sunglasses with UV protection to shield your eyes from glare.
Patients Concern
Disease/Condition Glossary
Glaucoma: It is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. If it is not treated in time, it may cause blindness. Usually, there are no symptoms of glaucoma initially, except the slow loss of vision gradually. However, some symptoms include visible rainbow-coloured circles around bright lights or blurred vision. Rarely, glaucoma can develop suddenly with intense pain in the eye, visual disturbance, or nausea.
Ocular hypertension: It is a condition caused by poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow). This leads to a build-up of excess fluid in the eye, resulting in increased pressure inside the eye without any damage to the optic nerve. If ocular hypertension is not controlled, it may lead to glaucoma.
FAQs
Netarsudil is used for the treatment of glaucoma and ocular hypertension.
Netarsudil works by increasing the outflow of aqueous humour, thereby helps lower the increased pressure in the eye.
Netarsudil might cause blurred vision for some time immediately after use. So, avoid driving or operating machinery until your vision is clear to prevent any mishappening.
Netarsudil is considered good to lower swelling and pressure within the eye, helping to prevent glaucoma-related complications like blindness and enhancing vision.
Netarsudil may not cure eye infections but, reduce intraocular pressure. If you have an eye infection, it is essential to consult a doctor for proper treatment. Do not self-medicate.
Netarsudil causes side effects such as blurred vision, instillation site pain, eye redness, and conjunctival haemorrhage (bright red patch on the conjunctiva). Please, consult your doctor if these persist longer.
No. Remove your contact lenses before using Netarsudil. The solution contains a preservative that may be absorbed by soft contact lenses and cause discoloration. Wait at least 15 minutes after applying the drops before reinserting your lenses. Consult your doctor if you have any concerns.
Netarsudil may begin lowering eye pressure within the first few hours after use. However, your eye specialist will usually assess its full effect after several weeks of regular daily treatment. Continue using it exactly as prescribed, even if you do not notice any immediate change.
Eye redness is a very common side effect of this medication and is usually mild and temporary. However, if the redness is accompanied by severe pain, discharge, itching, or sudden vision changes, contact your doctor right away.
The safety of this medication during pregnancy has not been fully established. If you are pregnant, planning to become pregnant, or breastfeeding, you should talk to your doctor to evaluate the benefits and risks before using these drops.
Keeping unopened bottles in the refrigerator ensures Netarsudil remains stable and effective until its expiration date. Once opened, the bottle can be kept at room temperature for up to 6 weeks. Talk to your pharmacist for more storage tips.
Do not stop using Netarsudil without consulting your doctor. Stopping treatment can cause your eye pressure to rise again, increasing the risk of optic nerve damage, glaucoma progression, and permanent vision loss. Continue using it exactly as prescribed.
Yes. If you are using other eye drops or eye medications, leave at least 5 minutes between each medication so they can be absorbed properly. Follow your doctor's instructions if a different schedule has been recommended.
Unlike some other glaucoma eye drops, Netarsudil is not widely associated with changing the color of your iris, though it frequently causes temporary redness of the white of the eye. Talk to your doctor if you notice any unusual changes in your eyes.
