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Nebivolol+valsartan

About Nebivolol+valsartan

Nebivolol+valsartan is a prescription medicine used to treat high blood pressure (hypertension). Its primary medical purpose is to lower elevated blood pressure levels, which helps reduce the workload on your heart and protects your blood vessels from long-term damage.

To get the best results from this medication, you should take it consistently every day, preferably at the same time. You can take this medicine with or without food. Making healthy lifestyle choices, such as adopting a low-sodium diet and engaging in regular physical activity, will significantly support the effectiveness of your treatment.

While taking Nebivolol+valsartan, some people may experience mild side effects like dizziness, headache, or tiredness. However, you should talk to your doctor immediately if you experience serious symptoms, such as severe dizziness, fainting, a very slow heartbeat, or signs of an allergic reaction like swelling of your face, lips, or throat.

Do not take this if you have severe liver damage, severe heart block, or if you are pregnant. If you have a history of asthma, diabetes, kidney disease, or blood circulation problems, you should talk to your doctor before starting this medicine to ensure it is safe for you.

This medicine can interact with alcohol, smoking, and certain other medications, which may cause your blood pressure to drop too low or increase your risk of side effects. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to discuss if this treatment is appropriate for you.

Uses of Nebivolol+valsartan

Nebivolol+valsartan is used in the treatment of Hypertension. The detailed uses of Nebivolol+valsartan are as follows: • Treating high blood pressure (hypertension): Nebivolol+valsartan combines two antihypertensive agents to effectively lower blood pressure and reduce the risk of heart attacks, strokes, and kidney problems. • Improving heart function and circulation: Nebivolol in Nebivolol+valsartan is a beta-blocker that slows heart rate and reduces the force of contraction, easing the heart’s workload and improving blood flow. • Relaxing blood vessels for smoother blood flow: Valsartan, an angiotensin II receptor blocker (ARB), prevents blood vessel constriction, allowing vessels to relax and blood to flow more freely. • Enhancing cardiovascular protection: By lowering blood pressure and reducing strain on the heart and arteries, Nebivolol+valsartan supports long-term heart health and helps prevent complications from chronic hypertension.

Medicinal Benefits

Nebivolol+valsartan helps lower and control high blood pressure through the combined action of two complementary medicines. Keeping your blood pressure within the target range helps protect your heart and other vital organs from long-term damage. Key benefits include:

  • Lowers High Blood Pressure: This medication relaxes blood vessels and helps improve blood flow, effectively reducing high blood pressure and making it easier for your heart to pump blood.
  • Protects Vital Organs: Maintaining healthy blood pressure helps reduce the risk of complications such as heart attack, stroke, kidney damage, and other problems associated with uncontrolled hypertension.
  • Provides Effective Combination Therapy: By combining two blood pressure-lowering medicines into a single tablet, this medication offers better blood pressure control for many people while reducing the number of pills needed each day, which may improve treatment adherence.

Directions for Use

  • Nebivolol+valsartan can be taken with or without food.
  • •Nebivolol+valsartan is usually taken once a day, or as prescribed by your doctor.
  • Swallow Nebivolol+valsartan as a whole with a glass of water.
  • Do not crush, break, or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nebivolol+valsartan

Common Side Effects (Usually mild):

  • Dizziness or lightheadedness
  • Headache
  • Feeling unusually tired or weak
  • Mild diarrhea or nausea

 

Serious Side Effects (Call a doctor right away):

  • Signs of a severe allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat
  • Unexplained muscle pain, tenderness, or weakness
  • A very slow, fast, or irregular heartbeat
  • Yellowing of the eyes or skin, or dark urine, which may indicate liver damage
  • Severe dizziness or fainting

Medicines Containing this Salt

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Drug Warnings

  • Do not stop treatment suddenly: Continue taking Nebivolol+valsartan as prescribed. Stopping it abruptly may cause your blood pressure to rise or worsen certain heart conditions. Your doctor will advise you if it needs to be discontinued.
  • Stand up slowly: Rise gradually from a sitting or lying position to help reduce dizziness, lightheadedness, and the risk of falls, especially when starting treatment.
  • Monitor your blood pressure: Check your blood pressure and heart rate regularly as advised by your healthcare provider and keep a record of your readings if recommended.
  • Be careful with activities requiring alertness: Avoid driving or operating machinery until you know how Nebivolol+valsartan affects you, as it may cause dizziness or drowsiness.
  • Inform your healthcare provider: Tell your doctor, dentist, or surgeon that you are taking Nebivolol+valsartan before any medical or dental procedure or before starting any new medication.

Drug Interactions

Inform your doctor about all the medicines you are using before using this, as they may interact with Nebivolol+valsartan and affect your treatment.

  • Other blood pressure medications: Taking Nebivolol+valsartan with other blood pressure-lowering drugs, including ACE inhibitors or aliskiren, can increase the risk of excessively low blood pressure and kidney issues.
  • Potassium supplements or potassium-sparing diuretics: Combining these can lead to dangerously high levels of potassium in your blood.
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Pain relievers like ibuprofen or naproxen can decrease the blood pressure-lowering effect of Nebivolol+valsartan and increase the risk of kidney damage.
  • Lithium: This medicine can increase the levels of lithium in your blood, which may lead to serious side effects.

Drug-Drug Interactions Checker List:

  • ALISKIREN
  • CYCLOSPORINE
  • FLUOXETINE
  • LITHIUM
  • RIFAMPIN
  • RITONAVIR
  • ASPIRIN
  • IBUPROFEN
  • NAPROXEN
  • CELECOXIB
  • DICLOFENAC
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is not advised to consume alcohol while taking Nebivolol+valsartan as it can increase the risk of side-effects.

    • Safety Warning

      Pregnancy

      unsafe

      It is not recommended to take Nebivolol+valsartan while you are pregnant (especially during the second and third trimesters) as it may be harmful to the unborn baby. Consult your doctor before using Nebivolol+valsartan if you are pregnant or planning for pregnancy.

    • Safety Warning

      Breast Feeding

      unsafe

      It is not recommended to take Nebivolol+valsartan while you are breastfeeding as it may cause harmful effects on the nursing baby. Your doctor may prescribe Nebivolol+valsartan if he/she thinks the benefits overweigh the risks.

    • Safety Warning

      Driving

      caution

      Nebivolol+valsartan may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

    • Safety Warning

      Liver

      caution

      Nebivolol+valsartan should be given with caution in patients with a history of liver diseases. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Nebivolol+valsartan should be given with caution in patients with a history of kidney diseases. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      unsafe

      Nebivolol+valsartan is not recommended for use in children and adolescents below 18 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Reduce sodium intake: Eat a low-salt diet to help your medication work more effectively in lowering your blood pressure.
    • Monitor potassium intake: This medication can increase potassium levels in your blood. Avoid using potassium-containing salt substitutes or taking potassium supplements without discussing it with your doctor first.
    • Stay active: Engage in moderate physical activity, such as walking, swimming, or cycling, for at least 30 minutes on most days of the week.
    • Limit alcohol: Avoid or severely limit alcohol consumption, as alcohol can interact with your medicine and cause your blood pressure to drop too low, making you dizzy or faint.
    • Track your blood pressure: Keep a regular log of your blood pressure readings at home and share them with your doctor during your check-ups.

    Special Advise

    • Do not take potassium supplements, a potassium-rich diet, or salt substitutes while using this medicine as it may increase potassium levels in the blood.

    • Your doctor may also monitor blood pressure, kidney function and potassium levels while taking this medicine.

    • Nebivolol+valsartan may cause orthostatic hypotension, so do not stand up too fast when rising from a sitting or lying position.

    • Do not stop taking this medication suddenly, as the abrupt stopping of this medicine may lead to chest pain or heart attack.

    Patients Concern

    Disease/Condition Glossary

    Hypertension: It is a chronic (long-term) condition in which blood pressure is elevated persistently at higher than normal levels. It occurs when the blood’s force against the wall of blood vessels is too high. This condition can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes damage to the brain, kidneys and eyes. The risk of high blood pressure complications increases with the following: obesity, smoking, diabetes, alcohol intake, lack of physical inactivity, stress and kidney diseases.

    FAQs

    Nebivolol+valsartan is used in the treatment of hypertension (high blood pressure).

    Nebivolol+valsartan contains Nebivolol and Valsartan. Nebivolol is a beta-blocker. It works specifically on the heart to reduce heart rate and lower blood pressure making it easier for the heart to pump blood to all parts of the body. Valsartan is an angiotensin-II receptor blocker (ARB). Angiotensin narrows the blood vessels increasing the blood pressure, therefore, blocking angiotensin can result in widening of the narrowed blood vessels. Together, Nebivolol+valsartan can effectively treat hypertension or high blood pressure.

    The common side-effects of Nebivolol+valsartan are nausea, vomiting, bradycardia (slow heartbeats), dizziness, hypotension (low blood pressure), hyperkalemia (increased potassium levels in the blood) and elevated liver enzymes. Inform your doctor immediately if any of these side-effects persist or get worse.

    Please inform your doctor before undergoing surgery or even any dental procedures (that requires taking anesthesia) if you are taking Nebivolol+valsartan as it needs to be stopped. Nebivolol+valsartan might lower the blood pressure further if taken along with general anesthesia.

    Nebivolol+valsartan is usually safe even it is taken for prolonged periods or as long as your doctor has prescribed it to you. However, please discuss with your doctor for further information/advice.

    Nebivolol+valsartan is probably safe when used for hypertension in diabetic patients. However, in cases such as diabetes with end-organ damage (damage to the major organs such as heart, kidney, brain and eyes), Nebivolol+valsartan is not recommended as it can result in kidney failure.

    No, you should not take Nebivolol+valsartan if you are pregnant. This medication can cause serious harm or death to an unborn baby, especially when taken during the second and third trimesters. If you become pregnant while taking this medicine, stop taking it and contact your doctor immediately. Talk to your doctor for safer alternatives.

    It is highly recommended to avoid or limit alcohol while taking this medicine. Alcohol can enhance the blood pressure-lowering effect of the medication, which can cause severe dizziness, lightheadedness, or fainting when you stand up. Talk to your doctor about safe limits.

    Dizziness is a common side effect, especially when you first start taking this medicine. Sit or lie down immediately if you feel lightheaded. To prevent dizziness, rise slowly from a sitting or lying position. If the dizziness is severe or does not go away, talk to your doctor.

    Yes, one of the active ingredients in Nebivolol+valsartan can cause your body to retain potassium, which may lead to high blood potassium levels. Avoid taking potassium supplements or using salt substitutes containing potassium without consulting your healthcare provider. Talk to your doctor to monitor your levels.

    No, you should never stop taking Nebivolol+valsartan suddenly, even if your blood pressure feels normal. High blood pressure often has no symptoms, and stopping the medicine abruptly can cause your blood pressure to spike dangerously. Any changes to your treatment must be supervised by your doctor.

    One of the ingredients in Nebivolol+valsartan may mask the physical warning signs of low blood sugar, such as a rapid heartbeat or palpitations. Sweating, however, is usually not affected. If you have diabetes, monitor your blood sugar closely and talk to your doctor about how to manage your condition safely while on this medicine.

    You should avoid taking non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, diclofenac, or naproxen regularly while taking Nebivolol+valsartan unless advised by your doctor. These medicines may reduce the blood pressure-lowering effect of Nebivolol+valsartan and increase the risk of kidney problems, especially with prolonged use. Consult your doctor or pharmacist before taking any pain relievers.

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